JP2004534031A - 心臓および循環器疾患の治療および予防を目的とする一日一回の治療のための経口制御放出医薬組成物 - Google Patents

心臓および循環器疾患の治療および予防を目的とする一日一回の治療のための経口制御放出医薬組成物 Download PDF

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Publication number
JP2004534031A
JP2004534031A JP2002588995A JP2002588995A JP2004534031A JP 2004534031 A JP2004534031 A JP 2004534031A JP 2002588995 A JP2002588995 A JP 2002588995A JP 2002588995 A JP2002588995 A JP 2002588995A JP 2004534031 A JP2004534031 A JP 2004534031A
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Prior art keywords
carvedilol
hours
released
pharmaceutical composition
controlled release
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Pending
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JP2002588995A
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English (en)
Japanese (ja)
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JP2004534031A5 (en:Method
Inventor
ディリプ、シャンティラル、シャングビ
バーラ、ラメシャ、アール．チャリー
ツィアウディン、ゼット．ティエブジ
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Sun Pharmaceutical Industries Ltd
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Sun Pharmaceutical Industries Ltd
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Publication of JP2004534031A publication Critical patent/JP2004534031A/ja
Publication of JP2004534031A5 publication Critical patent/JP2004534031A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Packaging Frangible Articles (AREA)
JP2002588995A 2001-05-17 2002-05-10 心臓および循環器疾患の治療および予防を目的とする一日一回の治療のための経口制御放出医薬組成物 Pending JP2004534031A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN464MU2001 IN191028B (en:Method) 2001-05-17 2001-05-17
PCT/IN2002/000118 WO2002092078A1 (en) 2001-05-17 2002-05-10 Oral controlled release pharmaceutical composition for one-a-day therapy for the treatment and prophylaxis of cardiac and circulatory diseases

Publications (2)

Publication Number Publication Date
JP2004534031A true JP2004534031A (ja) 2004-11-11
JP2004534031A5 JP2004534031A5 (en:Method) 2005-09-29

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ID=11097247

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002588995A Pending JP2004534031A (ja) 2001-05-17 2002-05-10 心臓および循環器疾患の治療および予防を目的とする一日一回の治療のための経口制御放出医薬組成物

Country Status (16)

Country Link
US (1) US20030035836A1 (en:Method)
EP (1) EP1395258A1 (en:Method)
JP (1) JP2004534031A (en:Method)
KR (1) KR20040037026A (en:Method)
CN (1) CN1525855A (en:Method)
AU (1) AU2002314515B2 (en:Method)
BE (1) BE1014328A7 (en:Method)
BR (1) BR0210976A (en:Method)
CA (1) CA2447005A1 (en:Method)
HU (1) HUP0400607A3 (en:Method)
IN (1) IN191028B (en:Method)
MX (1) MXPA03010501A (en:Method)
PL (1) PL370589A1 (en:Method)
RU (1) RU2003133446A (en:Method)
WO (1) WO2002092078A1 (en:Method)
ZA (1) ZA200309724B (en:Method)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013505970A (ja) * 2009-09-29 2013-02-21 ティーエスエイチ バイオファーム コーポレーション リミテッド 徐放性カルベジロール製剤
JPWO2011102506A1 (ja) * 2010-02-22 2013-06-17 第一三共株式会社 経口用徐放性固形製剤

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US20040253310A1 (en) 2001-09-21 2004-12-16 Gina Fischer Morphine polymer release system
EP2957281A1 (en) 2001-09-21 2015-12-23 Egalet Ltd. Polymer release system
DK1429734T3 (da) * 2001-09-21 2008-05-13 Egalet As Faste dispersioner af carvedilol til kontrolleret afgivelse
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
WO2003092622A2 (en) * 2002-04-30 2003-11-13 Sb Pharmco Puerto Rico Inc. Carvedilol monocitrate monohydrate
MXPA04012923A (es) 2002-06-27 2005-03-31 Sb Pharmco Inc Sales de fosfato de carvedilol y/o solvatos de las mismas, composiciones correspondientes y/o metodos de tratamiento.
CA2492084A1 (en) 2002-06-27 2004-01-08 Sb Pharmco Puerto Rico Inc. Carvedilol hydobromide
EP1562552A1 (en) 2002-11-08 2005-08-17 Egalet A/S Controlled release carvedilol compositions
AU2003283789A1 (en) * 2002-11-22 2004-06-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Beta-blockers having antioxidant and nitric oxide-donor activity
EP2301526B1 (en) 2003-03-26 2016-03-23 Egalet Ltd. Morphine controlled release system
DK1610768T3 (da) 2003-03-26 2008-09-22 Egalet As Matrikskompositioner til styret afgivelse af lægemiddelsubstanser
ATE445393T1 (de) * 2003-04-24 2009-10-15 Jagotec Ag Tablette mit gefärbtem kern
US7260685B2 (en) 2003-06-20 2007-08-21 Micron Technology, Inc. Memory hub and access method having internal prefetch buffers
HUE043958T2 (hu) * 2003-09-12 2019-09-30 Amgen Inc Cinakalcet HCl-t tartalmazó, gyors feloldódású készítmény
US7120743B2 (en) 2003-10-20 2006-10-10 Micron Technology, Inc. Arbitration system and method for memory responses in a hub-based memory system
US20050169994A1 (en) * 2003-11-25 2005-08-04 Burke Matthew D. Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
CA2547137A1 (en) * 2003-11-25 2005-06-09 Sb Pharmco Puerto Rico Inc. Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
WO2005051383A1 (en) 2003-11-25 2005-06-09 Sb Pharmco Puerto Rico Inc. Carvedilol salts, corresponding compositions, methods of delivery and/or treatment
US20070196396A1 (en) * 2004-02-11 2007-08-23 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
JP5161075B2 (ja) * 2005-06-03 2013-03-13 エガレット エイ／エス 分散媒体の第１フラクションとマトリックスの第２フラクションを有し、第２フラクションが胃腸の液体に少なくとも部分的に最初に曝される固形の医薬組成物
US8367112B2 (en) * 2006-02-28 2013-02-05 Alkermes Pharma Ireland Limited Nanoparticulate carverdilol formulations
US8703804B2 (en) 2006-03-26 2014-04-22 Uti Limited Partnership Ryanodine receptor inhibitors and methods relating thereto
EA015304B1 (ru) 2006-08-03 2011-06-30 Нитек Фарма Аг Лечение ревматоидного заболевания глюкокортикоидами с отсроченным высвобождением
US20080292695A1 (en) * 2006-12-01 2008-11-27 Kristin Arnold Carvedilol forms, compositions, and methods of preparation thereof
US20090028935A1 (en) * 2006-12-01 2009-01-29 Kristin Arnold Carvedilol forms, compositions, and methods of preparation thereof
US20100291205A1 (en) * 2007-01-16 2010-11-18 Egalet A/S Pharmaceutical compositions and methods for mitigating risk of alcohol induced dose dumping or drug abuse
WO2008114276A1 (en) * 2007-03-16 2008-09-25 Lupin Limited Novel oral controlled release composition of carvedilol
BRPI0701904A2 (pt) * 2007-04-27 2008-12-09 Libbs Farmaceutica Ltda forma farmacÊutica de liberaÇço controlada de princÍpios ativos com solubilidade dependente do baixo ph do meio e processo para preparar a forma farmacÊutica
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JP5749247B2 (ja) 2010-02-22 2015-07-15 第一三共株式会社 経口用徐放性固形製剤
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BR112015004190A2 (pt) 2012-09-03 2017-07-04 Daiichi Sankyo Co Ltd composição farmacêutica de liberação sustentada, e, método para produzir uma composição farmacêutica de liberação sustentada
KR102241487B1 (ko) 2013-02-20 2021-04-16 주식회사 종근당 제어방출 펠릿으로 된 약제학적 조성물
KR102158339B1 (ko) 2016-02-05 2020-09-21 삼진제약주식회사 인습성이 개선된 카르베딜롤 속방성 제제

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
JP2013505970A (ja) * 2009-09-29 2013-02-21 ティーエスエイチ バイオファーム コーポレーション リミテッド 徐放性カルベジロール製剤
US8883207B2 (en) 2009-09-29 2014-11-11 Tsh Biopharm Corporation Ltd. Controlled release carvedilol formulation
JPWO2011102506A1 (ja) * 2010-02-22 2013-06-17 第一三共株式会社 経口用徐放性固形製剤

Also Published As

Publication number Publication date
EP1395258A1 (en) 2004-03-10
AU2002314515B2 (en) 2007-08-16
MXPA03010501A (es) 2004-03-02
KR20040037026A (ko) 2004-05-04
BR0210976A (pt) 2004-10-05
CA2447005A1 (en) 2002-11-21
HUP0400607A2 (hu) 2004-07-28
CN1525855A (zh) 2004-09-01
US20030035836A1 (en) 2003-02-20
RU2003133446A (ru) 2005-03-10
IN191028B (en:Method) 2003-09-13
PL370589A1 (en) 2005-05-30
WO2002092078A1 (en) 2002-11-21
HUP0400607A3 (en) 2005-07-28
BE1014328A7 (fr) 2003-08-05
ZA200309724B (en) 2005-05-25

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