BR0210976A - Composição farmacêutica de liberação oral controlada para a terapia de uma vez ao dia e método para a obtenção de um controle desejado sobre os nìveis plasmáticos de carvedilol em seres humanos para a terapia de uma vez ao dia - Google Patents

Composição farmacêutica de liberação oral controlada para a terapia de uma vez ao dia e método para a obtenção de um controle desejado sobre os nìveis plasmáticos de carvedilol em seres humanos para a terapia de uma vez ao dia

Info

Publication number
BR0210976A
BR0210976A BR0210976-0A BR0210976A BR0210976A BR 0210976 A BR0210976 A BR 0210976A BR 0210976 A BR0210976 A BR 0210976A BR 0210976 A BR0210976 A BR 0210976A
Authority
BR
Brazil
Prior art keywords
once daily
therapy
carvedilol
daily therapy
pharmaceutical composition
Prior art date
Application number
BR0210976-0A
Other languages
English (en)
Inventor
Dilip Shantilal Shanghvi
R Bala Ramesha Chary
Z Ziauddin Tyebji
Original Assignee
Sun Pharmaceutical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Ind Ltd filed Critical Sun Pharmaceutical Ind Ltd
Publication of BR0210976A publication Critical patent/BR0210976A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Packaging Frangible Articles (AREA)
  • Indole Compounds (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA DE LIBERAçãO ORAL CONTROLADA PARA A TERAPIA DE UMA VEZ AO DIA E MéTODO PARA A OBTENçãO DE UM CONTROLE DESEJADO SOBRE OS NìVEIS PLASMáTICOS DE CARVEDILOL EM SERES HUMANOS PARA A TERAPIA DE UMA VEZ AO DIA". A presente invenção refere-se a uma composição farmacêutica de liberação oral controlada, para a terapia de uma vez ao dia, pra o tratamento e profilaxia de doenças cardíacas e circulatórias, que compreendem carvedilol ou seu sal ou éster farmaceuticamente aceitável, e excipientes de coeficiente de liberação controlada, onde a referida composição é adaptada para liberar o carvedilol de maneira controlada, de modo a proporcionar controle sobre níveis plasmáticos de carvedilol, de modo que a proporção dos níveis de pique plasmático com relação aos níveis plasmáticos em 24 horas após a administração, e o tempo de estadia media do carvedilol, estejam dentro da faixa desejável para a referida terapia de uma vez ao dia para o tratamento e a profilaxia de doenças cardíacas e circulatórias.
BR0210976-0A 2001-05-17 2002-05-10 Composição farmacêutica de liberação oral controlada para a terapia de uma vez ao dia e método para a obtenção de um controle desejado sobre os nìveis plasmáticos de carvedilol em seres humanos para a terapia de uma vez ao dia BR0210976A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN464MU2001 IN191028B (pt) 2001-05-17 2001-05-17
PCT/IN2002/000118 WO2002092078A1 (en) 2001-05-17 2002-05-10 Oral controlled release pharmaceutical composition for one-a-day therapy for the treatment and prophylaxis of cardiac and circulatory diseases

Publications (1)

Publication Number Publication Date
BR0210976A true BR0210976A (pt) 2004-10-05

Family

ID=11097247

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0210976-0A BR0210976A (pt) 2001-05-17 2002-05-10 Composição farmacêutica de liberação oral controlada para a terapia de uma vez ao dia e método para a obtenção de um controle desejado sobre os nìveis plasmáticos de carvedilol em seres humanos para a terapia de uma vez ao dia

Country Status (16)

Country Link
US (1) US20030035836A1 (pt)
EP (1) EP1395258A1 (pt)
JP (1) JP2004534031A (pt)
KR (1) KR20040037026A (pt)
CN (1) CN1525855A (pt)
AU (1) AU2002314515B2 (pt)
BE (1) BE1014328A7 (pt)
BR (1) BR0210976A (pt)
CA (1) CA2447005A1 (pt)
HU (1) HUP0400607A3 (pt)
IN (1) IN191028B (pt)
MX (1) MXPA03010501A (pt)
PL (1) PL370589A1 (pt)
RU (1) RU2003133446A (pt)
WO (1) WO2002092078A1 (pt)
ZA (1) ZA200309724B (pt)

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Also Published As

Publication number Publication date
WO2002092078A1 (en) 2002-11-21
AU2002314515B2 (en) 2007-08-16
US20030035836A1 (en) 2003-02-20
JP2004534031A (ja) 2004-11-11
HUP0400607A3 (en) 2005-07-28
PL370589A1 (en) 2005-05-30
BE1014328A7 (fr) 2003-08-05
EP1395258A1 (en) 2004-03-10
CA2447005A1 (en) 2002-11-21
ZA200309724B (en) 2005-05-25
MXPA03010501A (es) 2004-03-02
IN191028B (pt) 2003-09-13
HUP0400607A2 (hu) 2004-07-28
RU2003133446A (ru) 2005-03-10
KR20040037026A (ko) 2004-05-04
CN1525855A (zh) 2004-09-01

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010.