JP2004532809A5 - - Google Patents

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Publication number
JP2004532809A5
JP2004532809A5 JP2002547531A JP2002547531A JP2004532809A5 JP 2004532809 A5 JP2004532809 A5 JP 2004532809A5 JP 2002547531 A JP2002547531 A JP 2002547531A JP 2002547531 A JP2002547531 A JP 2002547531A JP 2004532809 A5 JP2004532809 A5 JP 2004532809A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002547531A
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JP2004532809A (ja
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Priority claimed from PCT/US2001/046846 external-priority patent/WO2002045749A2/en
Publication of JP2004532809A publication Critical patent/JP2004532809A/ja
Publication of JP2004532809A5 publication Critical patent/JP2004532809A5/ja
Pending legal-status Critical Current

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JP2002547531A 2000-11-02 2001-11-02 ホスホジエステラーゼ4型を阻害することによって、神経系の再生および修復を刺激するための方法 Pending JP2004532809A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24531900P 2000-11-02 2000-11-02
PCT/US2001/046846 WO2002045749A2 (en) 2000-11-02 2001-11-02 Methods for stimulating nervous system regeneration and repair by inhibition phosphodiesterase type 4

Publications (2)

Publication Number Publication Date
JP2004532809A JP2004532809A (ja) 2004-10-28
JP2004532809A5 true JP2004532809A5 (ja) 2005-12-22

Family

ID=22926184

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002547531A Pending JP2004532809A (ja) 2000-11-02 2001-11-02 ホスホジエステラーゼ4型を阻害することによって、神経系の再生および修復を刺激するための方法

Country Status (6)

Country Link
US (2) US20030229134A1 (ja)
EP (1) EP1343528A2 (ja)
JP (1) JP2004532809A (ja)
AU (1) AU2002241596A1 (ja)
CA (1) CA2427430A1 (ja)
WO (1) WO2002045749A2 (ja)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8153646B2 (en) 2000-08-10 2012-04-10 Dart Neuroscience (Cayman) Ltd. Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation
US9931318B2 (en) 2003-04-08 2018-04-03 Dart Neuroscience (Cayman) Ltd. Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation
RU2340600C2 (ru) 2001-10-16 2008-12-10 Мемори Фармасьютиклз Корпорейшн Производные 4-(4-алкокси-3-гидроксифенил)-2-пирролидона в качестве ингибиторов pde-4 для лечения неврологических синдромов
UA80957C2 (en) * 2001-11-01 2007-11-26 Sciclone Pharmaceuticals Inc Method of administering a thymosin alpha 1 peptide
US20030220280A1 (en) * 2002-02-07 2003-11-27 Bunge Mary Bartlett Schwann cell bridge implants and phosphodiesterase inhibitors to stimulate CNS nerve regeneration
US20060153827A1 (en) * 2002-08-15 2006-07-13 Gruskin Elliott A Chimeric protein
EP1613590A2 (en) 2003-04-16 2006-01-11 Memory Pharmaceutical Corporation 4-(3,4-disubstituted phenyl)-pyrrolidin-2-one compounds as phosphodiesterase 4 inhibitors
JP2006523719A (ja) 2003-04-18 2006-10-19 メモリー・ファーマシューティカルズ・コーポレイション ホスホジエステラーゼ4抑制剤としてのピラゾール誘導体
EP2460881B1 (en) * 2003-05-16 2017-05-03 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of CNS
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
US20090111812A1 (en) * 2004-06-14 2009-04-30 Musc Foundation For Research Development Methods for treating inflammatory disorders
WO2006044528A1 (en) 2004-10-15 2006-04-27 Memory Pharmaceuticals Corporation Pyrazole derivatives as phosphodiesterase 4 inhibitors
EP1802615A1 (en) 2004-10-20 2007-07-04 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors
US8309057B2 (en) 2005-06-10 2012-11-13 The Invention Science Fund I, Llc Methods for elevating neurotrophic agents
JP5189985B2 (ja) 2005-09-26 2013-04-24 アコーダ セラピューティクス、インク. コンドロイチナーゼabci変異体を用いた組成物およびその使用方法
WO2007048846A1 (de) * 2005-10-27 2007-05-03 Neuraxo Biopharmaceuticals Gmbh Verwendung von eisen chelatisierenden verbindungen, zyklisches adenosinmonophosphat erhöhende verbindungen oder kombinationen davon zur behandlung von axonalen läsionen im zns
US8927546B2 (en) * 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
EP2026813A2 (en) * 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
SG172602A1 (en) * 2006-05-19 2011-07-28 Helicon Therapeutics Inc Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation
BRPI0814624A2 (pt) 2007-07-11 2015-01-27 Medicinova Inc Tratamento de doença neurodegenerativa progresiva com ibudilaste
US8447409B2 (en) * 2008-10-15 2013-05-21 Cochlear Limited Electroneural interface for a medical implant
US20140038967A1 (en) 2011-03-17 2014-02-06 Algiax Pharmaceuticals Gmbh Novel use for imidazotriazinones
EP2685975A1 (en) 2011-03-17 2014-01-22 Algiax Pharmaceuticals GmbH Novel use of benzofuranylsulfonates
CN106458878B (zh) * 2014-03-18 2018-08-31 艾格埃克斯制药有限公司 2-氰基-3-环丙基-3-羟基-n-芳基-硫代丙烯酰胺衍生物
US20210031012A1 (en) 2018-01-26 2021-02-04 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor
WO2020106757A1 (en) 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
US11707610B2 (en) 2019-12-13 2023-07-25 Biora Therapeutics, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525329A (en) * 1992-05-21 1996-06-11 The Johns Hopkins University Inhibition of phosphodiesterase in olfactory mucosa
EP0755685A4 (en) * 1994-04-15 2000-05-03 Meiji Seika Kaisha PHARMACEUTICAL COMPOSITION FOR TREATING LATE DYSKINESIA
US5672622A (en) * 1994-04-21 1997-09-30 Berlex Laboratories, Inc. Treatment of multiple sclerosis
DE69633336T2 (de) * 1995-06-27 2005-09-22 Research Foundation Of Cuny Zusamenzetzung enthaltend einen inhibitor des myelin assoziierten glycoproteins (mag), welcher einer veränderten oder mutierten form von mag enthält
CA2340180A1 (en) * 1998-08-11 2000-02-24 Pfizer Products Inc. 1-aryl,-3-arylmethyl-1,8-naphthyridn-2(1h)-ones
US6268352B1 (en) * 1998-09-02 2001-07-31 The Regents Of The University Of California Promoters of neural regeneration

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