JP2004532198A5 - - Google Patents
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- Publication number
- JP2004532198A5 JP2004532198A5 JP2002571550A JP2002571550A JP2004532198A5 JP 2004532198 A5 JP2004532198 A5 JP 2004532198A5 JP 2002571550 A JP2002571550 A JP 2002571550A JP 2002571550 A JP2002571550 A JP 2002571550A JP 2004532198 A5 JP2004532198 A5 JP 2004532198A5
- Authority
- JP
- Japan
- Prior art keywords
- hiv
- pharmaceutical composition
- human antibody
- infection
- igg fraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004965 antibodies Human genes 0.000 claims 3
- 108090001123 antibodies Proteins 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000005721 HIV Infections Diseases 0.000 claims 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 claims 1
- 210000002966 Serum Anatomy 0.000 claims 1
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 1
- 238000001042 affinity chromatography Methods 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000011347 resin Substances 0.000 claims 1
- 229920005989 resin Polymers 0.000 claims 1
- URRBLVUOXIGNQR-HXUWFJFHSA-N [(1R)-1-phenylethyl] N-(2-aminoethyl)-N-[(3-methoxy-4-phenylmethoxyphenyl)methyl]carbamate Chemical compound C1([C@@H](C)OC(=O)N(CCN)CC=2C=C(C(=CC=2)OCC=2C=CC=CC=2)OC)=CC=CC=C1 URRBLVUOXIGNQR-HXUWFJFHSA-N 0.000 description 1
- 108010093001 anti-IgG Proteins 0.000 description 1
- 201000009910 diseases by infectious agent Diseases 0.000 description 1
- 230000003472 neutralizing Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
Description
この試験において、抗ＩｇＧ抗体のすべての調製物が９２ＨＴ５９３ＢおよびＮＬ-ＨＸ-ＡＤＡによるＰＢＭＣ感染を阻止し得ることが分かった。一方、ＳＦ１６２ＷＴに対する中和活性を観察しなかった。
Claims (2)
- ＨＩＶ−１感染の予防または処置用の医薬組成物であって、ヒトＩｇＧ全フラクションに対するヒト抗体を含み、該ヒト抗体が、ヒトＩｇＧ全フラクションに結合した樹脂を用いて、ＨＩＶ非感染正常人に由来する血清のアフィニティークロマトグラフィーにより得られ、そして、該ヒト抗体がＨＩＶ−１一次単離体を中和することができる、医薬組成物。
- ＨＩＶ−１感染の受動免疫療法のための、請求項１に記載の医薬組成物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI20010500 ITMI20010500A1 (it) | 2001-03-09 | 2001-03-09 | Auto-anticorpi naturali e il loro uso nella terapia di malattie da virus dell'immunodeficienza umana |
| IT2001MI002285A ITMI20012285A1 (it) | 2001-10-31 | 2001-10-31 | Anticorpi naturali attivi contro il virus hiv |
| PCT/EP2002/002454 WO2002072637A1 (en) | 2001-03-09 | 2002-03-06 | Natural antibodie active against hiv virus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004532198A JP2004532198A (ja) | 2004-10-21 |
| JP2004532198A5 true JP2004532198A5 (ja) | 2010-07-01 |
| JP4601252B2 JP4601252B2 (ja) | 2010-12-22 |
Family
ID=26332768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002571550A Expired - Fee Related JP4601252B2 (ja) | 2001-03-09 | 2002-03-06 | Ｈｉｖウイルスに対して活性な自然抗体 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US20040106771A1 (ja) |
| EP (1) | EP1366080B1 (ja) |
| JP (1) | JP4601252B2 (ja) |
| KR (1) | KR100871455B1 (ja) |
| CN (1) | CN1494554A (ja) |
| AP (1) | AP2003002852A0 (ja) |
| AT (1) | ATE346870T1 (ja) |
| AU (1) | AU2002257620B2 (ja) |
| BR (1) | BR0207931A (ja) |
| CA (1) | CA2440131A1 (ja) |
| CY (1) | CY1108852T1 (ja) |
| CZ (1) | CZ20032418A3 (ja) |
| DE (1) | DE60216422T2 (ja) |
| DK (1) | DK1366080T3 (ja) |
| EE (1) | EE200300377A (ja) |
| ES (1) | ES2278022T3 (ja) |
| HR (1) | HRP20030701A2 (ja) |
| HU (1) | HUP0303423A3 (ja) |
| IL (2) | IL157753A0 (ja) |
| MX (1) | MXPA03007976A (ja) |
| NO (1) | NO20033934L (ja) |
| PL (1) | PL366785A1 (ja) |
| PT (1) | PT1366080E (ja) |
| RS (1) | RS51011B (ja) |
| RU (1) | RU2003125554A (ja) |
| SI (1) | SI1366080T1 (ja) |
| TN (1) | TNSN03066A1 (ja) |
| WO (1) | WO2002072637A1 (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100330102A1 (en) | 2009-06-26 | 2010-12-30 | Wezen Biopharmaceuticals Srl A Socio Unico | Immunoglobulin preparation for the treatment of hiv-1 infection |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4639513A (en) * | 1984-02-02 | 1987-01-27 | Cuno Inc. | Intravenously injectable immunoglobulin G (IGG) and method for producing same |
| US5788687A (en) * | 1994-02-01 | 1998-08-04 | Caphco, Inc | Compositions and devices for controlled release of active ingredients |
| US5982866A (en) * | 1997-04-25 | 1999-11-09 | At&T Corporation | Method and apparatus for forwarding caller identification for a credit card or calling card call to an automatic number identification system of a telephone network |
| DE19815430B4 (de) * | 1998-04-07 | 2005-12-15 | T-Mobile Deutschland Gmbh | Verfahren zum Verbindungsaufbau von einem Mobilfunknetz zu einer Zielrufnummer eines privaten Kommunikationsnetzes |
| US6281336B1 (en) * | 1998-06-09 | 2001-08-28 | Statens Serum Institut | Process for producing immunoglobulins for intravenous administration and other immunoglobulin products |
| WO2000078018A1 (en) * | 1999-06-14 | 2000-12-21 | Wilshire Cellular, Inc. | Method and apparatus for communicating via virtual office telephone extensions |
| US6818247B1 (en) * | 2000-03-31 | 2004-11-16 | Advanced Cardiovascular Systems, Inc. | Ethylene vinyl alcohol-dimethyl acetamide composition and a method of coating a stent |
| US6970719B1 (en) * | 2000-06-15 | 2005-11-29 | Sprint Spectrum L.P. | Private wireless network integrated with public wireless network |
| US7336668B2 (en) * | 2001-09-24 | 2008-02-26 | Christopher Lyle Adams | Communication management system with line status notification for key switch emulation |
| US8040873B2 (en) * | 2001-11-07 | 2011-10-18 | Alcatel Lucent | Distributed integration of legacy PBX system with SIP networks |
| US20030105799A1 (en) * | 2001-12-03 | 2003-06-05 | Avaz Networks, Inc. | Distributed processing architecture with scalable processing layers |
| US7546143B2 (en) * | 2001-12-18 | 2009-06-09 | Fuji Xerox Co., Ltd. | Multi-channel quiet calls |
| US7146163B2 (en) * | 2002-10-01 | 2006-12-05 | Isp Operator Corporation | Sender-address-based telecommunications operator callback system and method |
| US20040086093A1 (en) * | 2002-10-29 | 2004-05-06 | Schranz Paul Steven | VoIP security monitoring & alarm system |
| US7904068B2 (en) * | 2003-06-06 | 2011-03-08 | At&T Intellectual Property I, L.P. | System and method for providing integrated voice and data services utilizing wired cordless access with unlicensed spectrum and wired access with licensed spectrum |
| US7715413B2 (en) * | 2003-10-23 | 2010-05-11 | Emerj, Inc. | Multi-network exchange system for telephony applications |
| CA2553209C (en) * | 2004-01-14 | 2012-05-01 | Research In Motion Limited | System and method for wirelessly provisioning a mobile communication device |
| US8254989B2 (en) * | 2004-07-29 | 2012-08-28 | Sprint Spectrum L.P. | Method and system for account balance restriction on application of cellular-PBX integration service |
| US20060294245A1 (en) * | 2005-06-22 | 2006-12-28 | Newstep Networks, Inc. | Method and system for a communications session join function to facilitate the provision of enhanced communications services |
| US20070264989A1 (en) * | 2005-10-03 | 2007-11-15 | Rajesh Palakkal | Rendezvous calling systems and methods therefor |
-
2002
- 2002-03-06 IL IL15775302A patent/IL157753A0/xx unknown
- 2002-03-06 EE EEP200300377A patent/EE200300377A/xx unknown
- 2002-03-06 KR KR1020037011648A patent/KR100871455B1/ko not_active IP Right Cessation
- 2002-03-06 AT AT02727364T patent/ATE346870T1/de not_active IP Right Cessation
- 2002-03-06 BR BR0207931-3A patent/BR0207931A/pt not_active IP Right Cessation
- 2002-03-06 ES ES02727364T patent/ES2278022T3/es not_active Expired - Lifetime
- 2002-03-06 US US10/469,870 patent/US20040106771A1/en not_active Abandoned
- 2002-03-06 JP JP2002571550A patent/JP4601252B2/ja not_active Expired - Fee Related
- 2002-03-06 PT PT02727364T patent/PT1366080E/pt unknown
- 2002-03-06 CN CNA028060636A patent/CN1494554A/zh active Pending
- 2002-03-06 EP EP02727364A patent/EP1366080B1/en not_active Expired - Lifetime
- 2002-03-06 AU AU2002257620A patent/AU2002257620B2/en not_active Ceased
- 2002-03-06 CZ CZ20032418A patent/CZ20032418A3/cs unknown
- 2002-03-06 RS YUP-701/03A patent/RS51011B/sr unknown
- 2002-03-06 MX MXPA03007976A patent/MXPA03007976A/es unknown
- 2002-03-06 HU HU0303423A patent/HUP0303423A3/hu unknown
- 2002-03-06 AP APAP/P/2003/002852A patent/AP2003002852A0/en unknown
- 2002-03-06 DE DE60216422T patent/DE60216422T2/de not_active Expired - Lifetime
- 2002-03-06 WO PCT/EP2002/002454 patent/WO2002072637A1/en active IP Right Grant
- 2002-03-06 RU RU2003125554/15A patent/RU2003125554A/ru not_active Application Discontinuation
- 2002-03-06 PL PL02366785A patent/PL366785A1/xx not_active IP Right Cessation
- 2002-03-06 DK DK02727364T patent/DK1366080T3/da active
- 2002-03-06 SI SI200230478T patent/SI1366080T1/sl unknown
- 2002-03-06 CA CA002440131A patent/CA2440131A1/en not_active Abandoned
-
2003
- 2003-07-08 TN TNPCT/EP2002/002454A patent/TNSN03066A1/en unknown
- 2003-09-02 HR HR20030701A patent/HRP20030701A2/xx not_active Application Discontinuation
- 2003-09-04 IL IL157753A patent/IL157753A/en not_active IP Right Cessation
- 2003-09-05 NO NO20033934A patent/NO20033934L/no not_active Application Discontinuation
-
2006
- 2006-08-22 US US11/507,450 patent/US20070020290A1/en not_active Abandoned
-
2007
- 2007-02-15 CY CY20071100205T patent/CY1108852T1/el unknown
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