JP2004530648A - 炎症により促進される咳の治療のためのｐ３８阻害剤の使用 - Google Patents
炎症により促進される咳の治療のためのｐ３８阻害剤の使用 Download PDFInfo
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24156400P | 2000-10-19 | 2000-10-19 | |
| PCT/US2001/050629 WO2002060869A2 (en) | 2000-10-19 | 2001-10-19 | Use of p38 inhibitors for the treatment of inflammation-enhanced cough |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2004530648A true JP2004530648A (ja) | 2004-10-07 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2002561020A Pending JP2004530648A (ja) | 2000-10-19 | 2001-10-19 | 炎症により促進される咳の治療のためのｐ３８阻害剤の使用 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1337255A4 (de) |
| JP (1) | JP2004530648A (de) |
| AU (1) | AU2002248269A1 (de) |
| WO (1) | WO2002060869A2 (de) |
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| US7235551B2 (en) | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
| DK1333833T3 (da) | 2000-10-23 | 2011-12-12 | Glaxosmithkline Llc | Ny trisubstitueret 8H-pyridol[2,3-d]pyrimidin-7-on-forbindelse til behandling af CSBP/RK/p38-kinnasemedierede sygdomme |
| CA2482022A1 (en) | 2002-04-19 | 2003-10-30 | Smithkline Beecham Corporation | Novel compounds |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| CA2603163A1 (en) | 2005-03-25 | 2006-10-05 | Glaxo Group Limited | Process for preparing pyrido[2,3-d]pyrimidin-7-one and 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one derivatives |
| AR053450A1 (es) | 2005-03-25 | 2007-05-09 | Glaxo Group Ltd | Derivados de 3,4-dihidro-pirimido(4,5-d)pirimidin-2-(1h)-ona 1,5,7 trisustituidos como inhibidores de la quinasa p38 |
| WO2006110298A2 (en) | 2005-03-25 | 2006-10-19 | Glaxo Group Limited | 8-alkyl/aryl-4-aryl-2-n- (alkylamino)-n'-substituted-n'-cyanoguanidino-8h-pyrido[2,3-d]pyrimidin-7-one compounds and use thereof |
| MY145281A (en) | 2005-03-25 | 2012-01-13 | Glaxo Group Ltd | Novel compounds |
| WO2006137421A1 (ja) * | 2005-06-21 | 2006-12-28 | Kyowa Hakko Kogyo Co., Ltd. | 局所投与剤 |
| US8461179B1 (en) | 2012-06-07 | 2013-06-11 | Deciphera Pharmaceuticals, Llc | Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| WO2019071147A1 (en) | 2017-10-05 | 2019-04-11 | Fulcrum Therapeutics, Inc. | INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD |
| SG11202007198WA (en) | 2018-01-31 | 2020-08-28 | Deciphera Pharmaceuticals Llc | Combination therapy for the treatment of gastrointestinal stromal tumors |
| CA3089630A1 (en) | 2018-01-31 | 2019-08-08 | Deciphera Pharmaceuticals, Llc | Combination therapy for the treatment of mastocytosis |
| TW202122082A (zh) | 2019-08-12 | 2021-06-16 | 美商迪賽孚爾製藥有限公司 | 治療胃腸道基質瘤方法 |
| EP4013412A1 (de) | 2019-08-12 | 2022-06-22 | Deciphera Pharmaceuticals, LLC | Ripretinib zur behandlung gastrointestinaler stromakarzinome |
| EP4084778B1 (de) | 2019-12-30 | 2023-11-01 | Deciphera Pharmaceuticals, LLC | Formulierungen eines amorphen kinase-inhibitors und verwendungsverfahren dafür |
| EP4084779B1 (de) | 2019-12-30 | 2024-10-09 | Deciphera Pharmaceuticals, LLC | Zusammensetzungen von 1-(4-brom-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorphenyl)-3-phenylharnstoff |
| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716972A (en) * | 1993-01-13 | 1998-02-10 | Smithkline Beecham Corporation | Pyridyl substituted imidazoles |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| ZA97175B (en) * | 1996-01-11 | 1997-11-04 | Smithkline Beecham Corp | Novel substituted imidazole compounds. |
| US5945418A (en) * | 1996-12-18 | 1999-08-31 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| NZ502702A (en) * | 1997-09-23 | 2002-10-25 | Astrazeneca Ab | Amide derivatives for the treatment of diseases mediated by TNF, IL-1, IL-6 or IL-8 |
| BR0014041A (pt) * | 1999-09-17 | 2003-07-15 | Smithkline Beecham Corp | Utilização de csaids em infecção por rinovìrus |
| WO2001038313A1 (en) * | 1999-11-23 | 2001-05-31 | Smithkline Beecham Corporation | 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p39 kINASE INHIBITORS |
-
2001
- 2001-10-19 WO PCT/US2001/050629 patent/WO2002060869A2/en not_active Application Discontinuation
- 2001-10-19 AU AU2002248269A patent/AU2002248269A1/en not_active Abandoned
- 2001-10-19 EP EP01997150A patent/EP1337255A4/de not_active Withdrawn
- 2001-10-19 JP JP2002561020A patent/JP2004530648A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1337255A4 (de) | 2006-01-25 |
| WO2002060869A3 (en) | 2003-01-03 |
| WO2002060869A2 (en) | 2002-08-08 |
| AU2002248269A1 (en) | 2002-08-12 |
| EP1337255A2 (de) | 2003-08-27 |
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