JP2004530642A - 障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用 - Google Patents

障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用 Download PDF

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JP2004530642A
JP2004530642A JP2002554120A JP2002554120A JP2004530642A JP 2004530642 A JP2004530642 A JP 2004530642A JP 2002554120 A JP2002554120 A JP 2002554120A JP 2002554120 A JP2002554120 A JP 2002554120A JP 2004530642 A JP2004530642 A JP 2004530642A
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alkyl
formula
phenyl
hydrogen
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JP2004530642A5 (enExample
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ゴッペルト,アンドレアス
アルツハイマー,クリスティアン
ケーゲル,ハイディ
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スウィッチ・バイオテック・アクチェンゲゼルシャフト
ルートヴィヒ−マクシミリアーンズ−ウニヴェルズィテート
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
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    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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    • G01N2800/205Scaling palpular diseases, e.g. psoriasis, pytiriasis

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JP2002554120A 2000-12-28 2001-12-27 障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用 Pending JP2004530642A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10065475A DE10065475A1 (de) 2000-12-28 2000-12-28 Verwendung von "intermediate-conductance" Kaliumkanälen und Modulatoren zur Diagnose und Behandlung von Krankheiten mit gestörter Keratinozytenfunktion
US27745301P 2001-03-20 2001-03-20
PCT/EP2001/015317 WO2002053171A2 (de) 2000-12-28 2001-12-27 Verwendung von 'intermediate-conductance kaliumkanälen und modulatoren zur diagnose und behandlung von krankheiten mit gestörter keratinozytenaktivität

Publications (2)

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JP2004530642A true JP2004530642A (ja) 2004-10-07
JP2004530642A5 JP2004530642A5 (enExample) 2005-12-22

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JP2002554120A Pending JP2004530642A (ja) 2000-12-28 2001-12-27 障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用

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EP (1) EP1345618B1 (enExample)
JP (1) JP2004530642A (enExample)
AT (1) ATE291435T1 (enExample)
CA (1) CA2433041A1 (enExample)
WO (1) WO2002053171A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10250870A1 (de) * 2002-10-31 2004-05-13 Switch Biotech Ag Zusammensetzung enthaltend Aktivatoren von IK-Kaliumkanälen und Calcineurin-Antagonisten und deren Verwendung
WO2004064835A1 (en) * 2003-01-17 2004-08-05 Neurosearch A/S Use of ion channel modulating agents for treating pain
US7851431B2 (en) * 2005-07-27 2010-12-14 Prescription Dispensing Laboratories Treatment of actinic keratoses with calcium channel blockers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569935A (en) * 1983-03-17 1986-02-11 University Of Tennessee Research Corp. Topical treatment of psoriasis with imidazole antibiotics
DE3563964D1 (en) * 1984-10-16 1988-09-01 Synthelabo Piperidine derivatives, their preparation and their therapeutical application
GB2273873A (en) * 1992-12-23 1994-07-06 Univ Sheffield Treatment of psoriasis
WO1997018332A1 (en) * 1995-11-13 1997-05-22 Brandeis University Regulation of cancer-causing tyrosine kinases by potassium ion conductance
US6797486B2 (en) * 1996-09-11 2004-09-28 Icagen, Incorporated Small and intermediate conductance, calcium-activated potassium channels and uses thereof
AU1224599A (en) * 1997-11-14 1999-06-07 Neurosearch A/S Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
JPH11209302A (ja) * 1998-01-21 1999-08-03 Pola Chem Ind Inc 抗掻痒剤
WO2000033834A1 (en) * 1998-12-04 2000-06-15 Neurosearch A/S Use of isatin derivatives as ion channel activating agents
AU760250B2 (en) * 1998-12-04 2003-05-08 Neurosearch A/S New benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents
JP2002531539A (ja) * 1998-12-04 2002-09-24 ニューロサーチ、アクティーゼルスカブ イオンチャネル調節剤
JP2002533318A (ja) * 1998-12-22 2002-10-08 ニューロサーチ、アクティーゼルスカブ イオンチャネル調節剤

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EP1345618A2 (de) 2003-09-24
ATE291435T1 (de) 2005-04-15
EP1345618B1 (de) 2005-03-23
WO2002053171A2 (de) 2002-07-11
CA2433041A1 (en) 2002-07-11
WO2002053171A3 (de) 2003-03-20

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