JP2004530635A - 多成分抗酸化性化合物、該化合物を含有する薬学的組成物、および酸化的ストレスを軽減または防止するためのそれらの使用 - Google Patents
多成分抗酸化性化合物、該化合物を含有する薬学的組成物、および酸化的ストレスを軽減または防止するためのそれらの使用 Download PDFInfo
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| GB0026254A GB2368339B (en) | 2000-10-26 | 2000-10-26 | Complex incorporating a plurality of antioxidants |
| PCT/IL2001/000984 WO2002034202A2 (en) | 2000-10-26 | 2001-10-25 | Multi-component antioxidant compounds, pharmaceutical compositions containing same and their use for reducing or preventing oxidative stress |
Publications (2)
| Publication Number | Publication Date |
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| JP2004530635A true JP2004530635A (ja) | 2004-10-07 |
| JP2004530635A5 JP2004530635A5 (cg-RX-API-DMAC7.html) | 2005-04-21 |
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| JP2002537256A Pending JP2004530635A (ja) | 2000-10-26 | 2001-10-25 | 多成分抗酸化性化合物、該化合物を含有する薬学的組成物、および酸化的ストレスを軽減または防止するためのそれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20070287662A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1333809A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2004530635A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002212661A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2427005A1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB2368339B (cg-RX-API-DMAC7.html) |
| IL (2) | IL155497A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002034202A2 (cg-RX-API-DMAC7.html) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014504598A (ja) * | 2011-01-20 | 2014-02-24 | ワンデイ − バイオテク アンド ファーマ リミテッド | 抗酸化、抗炎症、抗放射線、金属キレート化合物およびその使用 |
| JP2014513098A (ja) * | 2011-04-26 | 2014-05-29 | レトロトップ、 インコーポレイテッド | 神経変性障害および筋疾患に関与するｐｕｆａ |
| US10052299B2 (en) | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| US10058522B2 (en) | 2011-04-26 | 2018-08-28 | Retrotope, Inc. | Oxidative retinal diseases |
| US10058612B2 (en) | 2011-04-26 | 2018-08-28 | Retrotope, Inc. | Impaired energy processing disorders and mitochondrial deficiency |
| US10154978B2 (en) | 2011-04-26 | 2018-12-18 | Retrotope, Inc. | Disorders implicating PUFA oxidation |
| US11447441B2 (en) | 2015-11-23 | 2022-09-20 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| US11779910B2 (en) | 2020-02-21 | 2023-10-10 | Biojiva Llc | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
| US12673037B2 (en) | 2021-02-05 | 2026-07-07 | Biojiva Llc | Methods of treating amyotrophic lateral sclerosis |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2368339B (en) | 2000-10-26 | 2002-09-18 | Yissum Res Dev Co | Complex incorporating a plurality of antioxidants |
| WO2003026684A1 (en) * | 2001-09-27 | 2003-04-03 | The Mental Health Research Institute Of Victoria | Modulation of physiological processes and agents useful for same |
| US20060211628A1 (en) * | 2002-08-02 | 2006-09-21 | Daphne Atlas | Treatment of multiple sclerosis with brain targeted anti oxidant compounds |
| AU2004293477A1 (en) | 2003-11-25 | 2005-06-09 | University Of Rochester | Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof |
| US8895032B2 (en) | 2009-03-27 | 2014-11-25 | Central Michigan University | Dendritic nano-antioxidants |
| WO2014016831A1 (en) | 2012-07-23 | 2014-01-30 | Oneday - Biotech And Pharma Ltd. | Glutathione-elevating compositions and uses thereof |
| EP2877194A4 (en) * | 2012-07-25 | 2016-03-16 | Oneday Biotech And Pharma Ltd | Compositions and methods for increasing carnitine concentration in muscle tissue |
| WO2016009341A1 (en) | 2014-07-14 | 2016-01-21 | Radikal Therapeutics Inc. | Thioredoxin mimetic prodrugs and uses thereof |
| WO2026163188A1 (en) * | 2025-01-31 | 2026-08-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Antiepileptic drugs and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4738841A (en) * | 1985-08-28 | 1988-04-19 | Repligen Corporation | Use of thioredoxin, thioredoxin-derived, or thioredoxin-like dithiol peptides in hair care preparations |
| US4966848A (en) * | 1988-02-08 | 1990-10-30 | The General Hospital Corporation | Isolation, purification, characterization, cloning and sequencing of N α-acetyltransferase |
| KR0141693B1 (ko) * | 1988-08-12 | 1998-06-15 | 나까무라 하루후미 | 펩티드 유도체 및 항치매제 |
| US5223421A (en) * | 1989-10-25 | 1993-06-29 | The General Hospital Corporation | Identification of methionine Nα-acetyltransferase |
| IT1243911B (it) * | 1990-11-19 | 1994-06-28 | Zambon Spa | Composizioni per la terapia mucolitica |
| US5464825A (en) * | 1991-03-14 | 1995-11-07 | Cornell Research Foundation, Inc. | Raising glutathione equivalent levels using N-acyl glutathione monoesters |
| US5272252A (en) * | 1991-11-04 | 1993-12-21 | Merrell Dow Pharmaceuticals Inc. | Synthetic lung surfactant having antioxidant properties |
| US5869615A (en) * | 1994-01-03 | 1999-02-09 | Washington University | Modified complement proteases |
| US5688489A (en) * | 1995-09-15 | 1997-11-18 | Resolution Pharmaceuticals, Inc. | Non-receptor mediated imaging agents |
| SE9503679D0 (sv) * | 1995-10-20 | 1995-10-20 | Pharmacia Ab | Antioxidants |
| US5744593A (en) * | 1996-02-15 | 1998-04-28 | Heska Corporation | Parasitic helminth larval thiol specific antioxidant proteins and nucleic acid molecules |
| AU3643497A (en) * | 1996-06-28 | 1998-01-21 | National Jewish Center For Immunology And Respiratory Medicine | Use of thioredoxin-like molecules for induction of mnsod to treat oxidative damage |
| US5874468A (en) * | 1996-12-26 | 1999-02-23 | Yissum | Brain targeted low molecular weight hydrophobic antioxidant compounds |
| US5906811A (en) * | 1997-06-27 | 1999-05-25 | Thione International, Inc. | Intra-oral antioxidant preparations |
| WO1999050286A2 (en) | 1998-03-31 | 1999-10-07 | University Of Cincinnati | Antioxidant peptides derived from apolipoprotein a-iv |
| US6686443B1 (en) * | 2000-05-26 | 2004-02-03 | The Regents Of The University Of California | Chemical reagents for formation of disulfide bonds in peptides |
| SV2003000617A (es) | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
| GB2368339B (en) | 2000-10-26 | 2002-09-18 | Yissum Res Dev Co | Complex incorporating a plurality of antioxidants |
| US20030109457A1 (en) * | 2001-10-25 | 2003-06-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Multi-component antioxidant compounds, pharmaceutical compositions containing same and their use for reducing or preventing oxidative stress |
-
2000
- 2000-10-26 GB GB0026254A patent/GB2368339B/en not_active Expired - Fee Related
-
2001
- 2001-10-25 IL IL15549701A patent/IL155497A0/xx unknown
- 2001-10-25 EP EP01980877A patent/EP1333809A4/en not_active Withdrawn
- 2001-10-25 WO PCT/IL2001/000984 patent/WO2002034202A2/en not_active Ceased
- 2001-10-25 JP JP2002537256A patent/JP2004530635A/ja active Pending
- 2001-10-25 CA CA002427005A patent/CA2427005A1/en not_active Abandoned
- 2001-10-25 AU AU2002212661A patent/AU2002212661A1/en not_active Abandoned
-
2003
- 2003-04-15 IL IL155497A patent/IL155497A/en not_active IP Right Cessation
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2007
- 2007-05-04 US US11/797,590 patent/US20070287662A1/en not_active Abandoned
-
2011
- 2011-04-14 US US13/086,429 patent/US20110190195A1/en not_active Abandoned
-
2012
- 2012-04-25 US US13/455,155 patent/US8530407B2/en not_active Expired - Fee Related
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11510888B2 (en) | 2009-10-30 | 2022-11-29 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| US10052299B2 (en) | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| USRE49238E1 (en) | 2009-10-30 | 2022-10-11 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| JP2014504598A (ja) * | 2011-01-20 | 2014-02-24 | ワンデイ − バイオテク アンド ファーマ リミテッド | 抗酸化、抗炎症、抗放射線、金属キレート化合物およびその使用 |
| US10058612B2 (en) | 2011-04-26 | 2018-08-28 | Retrotope, Inc. | Impaired energy processing disorders and mitochondrial deficiency |
| US10058522B2 (en) | 2011-04-26 | 2018-08-28 | Retrotope, Inc. | Oxidative retinal diseases |
| US10154983B2 (en) | 2011-04-26 | 2018-12-18 | Retrotope, Inc. | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| US11241409B2 (en) | 2011-04-26 | 2022-02-08 | Retrotope, Inc. | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| US11285125B2 (en) | 2011-04-26 | 2022-03-29 | Retrotope, Inc. | Oxidative retinal diseases |
| US12156860B2 (en) | 2011-04-26 | 2024-12-03 | Biojiva Llc | Disorders implicating PUFA oxidation |
| JP2014513098A (ja) * | 2011-04-26 | 2014-05-29 | レトロトップ、 インコーポレイテッド | 神経変性障害および筋疾患に関与するｐｕｆａ |
| US10154978B2 (en) | 2011-04-26 | 2018-12-18 | Retrotope, Inc. | Disorders implicating PUFA oxidation |
| US11453637B2 (en) | 2015-11-23 | 2022-09-27 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| US12060324B2 (en) | 2015-11-23 | 2024-08-13 | Biojiva Llc | Site-specific isotopic labeling of 1,4-diene systems |
| US11447441B2 (en) | 2015-11-23 | 2022-09-20 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| US11779910B2 (en) | 2020-02-21 | 2023-10-10 | Biojiva Llc | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
| US12673037B2 (en) | 2021-02-05 | 2026-07-07 | Biojiva Llc | Methods of treating amyotrophic lateral sclerosis |
Also Published As
| Publication number | Publication date |
|---|---|
| US20120264676A1 (en) | 2012-10-18 |
| GB2368339B (en) | 2002-09-18 |
| CA2427005A1 (en) | 2002-05-02 |
| GB2368339A (en) | 2002-05-01 |
| EP1333809A2 (en) | 2003-08-13 |
| EP1333809A4 (en) | 2007-09-26 |
| US8530407B2 (en) | 2013-09-10 |
| IL155497A (en) | 2009-11-18 |
| WO2002034202A3 (en) | 2002-07-18 |
| AU2002212661A1 (en) | 2002-05-06 |
| IL155497A0 (en) | 2003-11-23 |
| WO2002034202A2 (en) | 2002-05-02 |
| US20070287662A1 (en) | 2007-12-13 |
| US20110190195A1 (en) | 2011-08-04 |
| GB0026254D0 (en) | 2000-12-13 |
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