JP2004527206A - Rykタンパク質を使用する新脈管形成の調節方法 - Google Patents

Rykタンパク質を使用する新脈管形成の調節方法 Download PDF

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Publication number
JP2004527206A
JP2004527206A JP2001582388A JP2001582388A JP2004527206A JP 2004527206 A JP2004527206 A JP 2004527206A JP 2001582388 A JP2001582388 A JP 2001582388A JP 2001582388 A JP2001582388 A JP 2001582388A JP 2004527206 A JP2004527206 A JP 2004527206A
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Japan
Prior art keywords
seq
protein
ryk
variant
amino acid
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Pending
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JP2001582388A
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English (en)
Japanese (ja)
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JP2004527206A5 (es
Inventor
ロツニアク,ステイーブ
ドウボワ−ストリングフエロー,ナタリー・エイ
ゾロトレブ,アルヤ
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Bayer Corp
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Miles Inc
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Application filed by Miles Inc filed Critical Miles Inc
Publication of JP2004527206A publication Critical patent/JP2004527206A/ja
Publication of JP2004527206A5 publication Critical patent/JP2004527206A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2001582388A 2000-05-10 2001-05-09 Rykタンパク質を使用する新脈管形成の調節方法 Pending JP2004527206A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56878300A 2000-05-10 2000-05-10
PCT/US2001/015043 WO2001085789A2 (en) 2000-05-10 2001-05-09 Extracellular domain of ryk protein for regulating angiogenesis

Publications (2)

Publication Number Publication Date
JP2004527206A true JP2004527206A (ja) 2004-09-09
JP2004527206A5 JP2004527206A5 (es) 2008-06-26

Family

ID=24272718

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001582388A Pending JP2004527206A (ja) 2000-05-10 2001-05-09 Rykタンパク質を使用する新脈管形成の調節方法

Country Status (13)

Country Link
EP (1) EP1287121A2 (es)
JP (1) JP2004527206A (es)
AR (1) AR028424A1 (es)
AU (1) AU2001261343A1 (es)
CA (1) CA2408349A1 (es)
CO (1) CO5300464A1 (es)
DO (1) DOP2001000164A (es)
EC (1) ECSP014068A (es)
GT (1) GT200100079A (es)
PE (1) PE20011218A1 (es)
SV (1) SV2002000442A (es)
UY (1) UY26696A1 (es)
WO (1) WO2001085789A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066087A2 (en) * 2002-02-06 2003-08-14 Developgen Aktiengesellschaft Für Entwicklungsbiologische Forschung Kinases involved in the regulation of energy homeostasis
JO3283B1 (ar) 2011-04-26 2018-09-16 Sanofi Sa تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI)
DK3170005T3 (da) 2014-07-18 2019-07-08 Sanofi Sa Fremgangsmåde til forudsigelse af resultatet af en behandling med aflibercept hos en patient, der mistænkes for at lide af cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07506969A (ja) * 1992-05-11 1995-08-03 ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ レセプタ型チロシンキナーゼ類似の分子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19980701950A (ko) * 1994-12-23 1998-06-25 에드워드 에이. 맥더모 2세, 로이드 제이. 오울드 분석, 리셉터 단백질 및 리간드
DE69930662T2 (de) * 1998-06-11 2006-12-28 Astrazeneca Ab Humane rezeptortyrosinkinase
ATE406907T1 (de) * 1998-10-28 2008-09-15 Cornell Res Foundation Inc Methoden zur regulierung der angiogenese und vaskuläre integrität mittels trk rezeptor liganden bdnf, nt-3 und nt-4

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07506969A (ja) * 1992-05-11 1995-08-03 ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ レセプタ型チロシンキナーゼ類似の分子

Also Published As

Publication number Publication date
AU2001261343A1 (en) 2001-11-20
GT200100079A (es) 2001-12-31
CO5300464A1 (es) 2003-07-31
SV2002000442A (es) 2002-07-03
ECSP014068A (es) 2002-02-25
AR028424A1 (es) 2003-05-07
WO2001085789A2 (en) 2001-11-15
WO2001085789A3 (en) 2002-05-16
PE20011218A1 (es) 2002-02-01
CA2408349A1 (en) 2001-11-15
EP1287121A2 (en) 2003-03-05
UY26696A1 (es) 2001-12-28
DOP2001000164A (es) 2002-05-15

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