JP2004525922A5 - - Google Patents
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- Publication number
- JP2004525922A5 JP2004525922A5 JP2002573034A JP2002573034A JP2004525922A5 JP 2004525922 A5 JP2004525922 A5 JP 2004525922A5 JP 2002573034 A JP2002573034 A JP 2002573034A JP 2002573034 A JP2002573034 A JP 2002573034A JP 2004525922 A5 JP2004525922 A5 JP 2004525922A5
- Authority
- JP
- Japan
- Prior art keywords
- component
- light chain
- agent
- amino acid
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/810,601 US6831059B2 (en) | 2000-10-20 | 2001-03-15 | Compositions and methods for treating gonadotrophin related illnesses |
| PCT/US2002/007379 WO2002074327A2 (en) | 2001-03-15 | 2002-03-11 | Compositions and methods for treating gonadotrophin related illnesses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010106073A Division JP2010174037A (ja) | 2001-03-15 | 2010-05-06 | ゴナドトロピン関連疾患を治療するための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004525922A JP2004525922A (ja) | 2004-08-26 |
| JP2004525922A5 true JP2004525922A5 (https=) | 2005-12-22 |
Family
ID=25204201
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002573034A Withdrawn JP2004525922A (ja) | 2001-03-15 | 2002-03-11 | ゴナドトロピン関連疾患を治療するための組成物および方法 |
| JP2010106073A Withdrawn JP2010174037A (ja) | 2001-03-15 | 2010-05-06 | ゴナドトロピン関連疾患を治療するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010106073A Withdrawn JP2010174037A (ja) | 2001-03-15 | 2010-05-06 | ゴナドトロピン関連疾患を治療するための組成物および方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US6831059B2 (https=) |
| EP (1) | EP1368053A4 (https=) |
| JP (2) | JP2004525922A (https=) |
| WO (1) | WO2002074327A2 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7227010B2 (en) * | 1993-09-21 | 2007-06-05 | United States Of America As Represented By The Secretary Of The Army | Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy |
| US7192596B2 (en) * | 1996-08-23 | 2007-03-20 | The Health Protection Agency Ipsen Limited | Recombinant toxin fragments |
| HK1046020B (en) | 1999-08-25 | 2007-05-11 | Allergan, Inc. | Activatable recombinant neurotoxins |
| US7838007B2 (en) | 1999-12-07 | 2010-11-23 | Allergan, Inc. | Methods for treating mammary gland disorders |
| US7838008B2 (en) * | 1999-12-07 | 2010-11-23 | Allergan, Inc. | Methods for treating diverse cancers |
| EP1301213B1 (en) * | 2000-07-21 | 2017-01-18 | ReVance Therapeutics, Inc. | Multi-component biological transport systems |
| US7273722B2 (en) * | 2000-11-29 | 2007-09-25 | Allergan, Inc. | Neurotoxins with enhanced target specificity |
| CZ303658B6 (cs) * | 2001-02-01 | 2013-02-06 | F. Hoffmann-La Roche Ag | Zpusob rekombinantní produkce trypsinu |
| US8071550B2 (en) * | 2003-03-03 | 2011-12-06 | Allergan, Inc. | Methods for treating uterine disorders |
| CN1946431B (zh) | 2004-03-03 | 2011-12-07 | 雷文斯治疗公司 | 用于肉毒毒素的局部施用和透皮递送的组合物和方法 |
| CA2558676C (en) | 2004-03-03 | 2019-04-16 | Essentia Biosystems, Inc. | Compositions and methods for topical diagnostic and therapeutic transport |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| EP1570855A1 (fr) * | 2004-03-04 | 2005-09-07 | Claude Le Louarn | Utilisation de toxine botulique pour préparer un médicament destiné à prévenir la pousse de poils |
| US7514088B2 (en) * | 2005-03-15 | 2009-04-07 | Allergan, Inc. | Multivalent Clostridial toxin derivatives and methods of their use |
| US7811584B2 (en) | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
| US7897147B2 (en) * | 2004-10-20 | 2011-03-01 | Allergan, Inc. | Treatment of premenstrual disorders |
| JP4994241B2 (ja) * | 2004-11-22 | 2012-08-08 | ニューヨーク・ユニバーシティ | 遺伝子操作されたクロストリジウム遺伝子、操作された遺伝子によりコードされるタンパク質、およびその使用 |
| GB0426397D0 (en) | 2004-12-01 | 2005-01-05 | Health Prot Agency | Fusion proteins |
| CN101160318A (zh) | 2005-03-03 | 2008-04-09 | 雷文斯治疗公司 | 用于局部施用和经皮肤递送寡肽的组合物和方法 |
| SG160357A1 (en) | 2005-03-03 | 2010-04-29 | Revance Therapeutics Inc | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| US7419675B2 (en) * | 2005-05-26 | 2008-09-02 | Allergan, Inc. | Method for treating peritoneal adhesions |
| ES2369558T3 (es) * | 2005-09-19 | 2011-12-01 | Allergan, Inc. | Toxinas clostridiales y toxinas clostridiales activables. |
| NZ568216A (en) | 2005-11-17 | 2012-09-28 | Revance Therapeutics Inc | Compositions and methods of topical application and transdermal delivery of botulinum toxins with reduced non-toxin proteins |
| EP2604284A1 (en) * | 2007-02-16 | 2013-06-19 | KTB Tumorforschungsgesellschaft mbH | Receptor And Antigen Targeted Prodrug |
| CA2727082C (en) * | 2008-06-12 | 2019-02-26 | Syntaxin Limited | Fusion proteins for use in suppression of acromegaly |
| US8796216B2 (en) | 2008-06-12 | 2014-08-05 | Syntaxin Limited | Suppression of neuroendocrine diseases |
| ES2426667T3 (es) * | 2008-09-09 | 2013-10-24 | Susanne Grafe | Toxina botulínica para introducir infertilidad temporal en un vertebrado (por ejemplo, un ser humano) |
| US8968210B2 (en) | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
| US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
| US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
| US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
| US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
| GB0820970D0 (en) * | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
| EP2649985A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (III) |
| EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
| EP2836193B1 (en) | 2012-04-13 | 2018-01-31 | Lubrizol Advanced Materials, Inc. | Compounds which inhibit neuronal exocytosis (ii) |
| EP2649983A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (II) |
| WO2014117148A1 (en) | 2013-01-28 | 2014-07-31 | New York University | Treatment methods using atoxic neurotoxin derivatives |
| EP3230457B1 (en) | 2014-12-09 | 2021-06-30 | New York University | Clostridial neurotoxin fusion proteins, propeptide fusions, their expression, and use |
| WO2020220085A1 (en) * | 2019-05-02 | 2020-11-05 | The University Of Sydney | Peptide derivatives and conjugates thereof for treating cancer |
| US11338016B2 (en) | 2020-05-20 | 2022-05-24 | Howard University | C-terminal fragment of tetanus toxin (Hc) for treatment of depression |
| KR102942184B1 (ko) | 2020-07-23 | 2026-03-20 | (주)메디톡스 | 암 치료제 |
| WO2022019583A1 (ko) * | 2020-07-23 | 2022-01-27 | (주)메디톡스 | 엑소좀-매개된 질환 치료제 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5186090A (en) | 1989-02-23 | 1990-09-26 | Colorado State University Research Foundation | Gnrh analogs for destroying gonadotrophs |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| US6005086A (en) | 1995-01-13 | 1999-12-21 | The Salk Institute For Biological Studies | Farnesoid activated receptor polypeptides, and nucleic acid encoding the same |
| GB9508204D0 (en) | 1995-04-21 | 1995-06-07 | Speywood Lab Ltd | A novel agent able to modify peripheral afferent function |
| GB9617671D0 (en) * | 1996-08-23 | 1996-10-02 | Microbiological Res Authority | Recombinant toxin fragments |
| US5939070A (en) | 1996-10-28 | 1999-08-17 | Wisconsin Alumni Research Foundation | Hybrid botulinal neurotoxins |
| GB9721189D0 (en) | 1997-10-08 | 1997-12-03 | Speywood Lab The Limited | Analgesic conjugates |
| GB9907429D0 (en) | 1999-03-31 | 1999-05-26 | Microbiological Res Authority | Modulation of C-fibre activity |
| US6139845A (en) * | 1999-12-07 | 2000-10-31 | Allergan Sales, Inc. | Method for treating cancer with a neurotoxin |
| US6827931B1 (en) | 2000-10-20 | 2004-12-07 | Allergan, Inc. | Method for treating endocrine disorders |
-
2001
- 2001-03-15 US US09/810,601 patent/US6831059B2/en not_active Expired - Lifetime
-
2002
- 2002-03-11 JP JP2002573034A patent/JP2004525922A/ja not_active Withdrawn
- 2002-03-11 WO PCT/US2002/007379 patent/WO2002074327A2/en not_active Ceased
- 2002-03-11 EP EP02721347A patent/EP1368053A4/en not_active Ceased
-
2010
- 2010-05-06 JP JP2010106073A patent/JP2010174037A/ja not_active Withdrawn
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