JP2004525079A5 - - Google Patents

Download PDF

Info

Publication number
JP2004525079A5
JP2004525079A5 JP2002531975A JP2002531975A JP2004525079A5 JP 2004525079 A5 JP2004525079 A5 JP 2004525079A5 JP 2002531975 A JP2002531975 A JP 2002531975A JP 2002531975 A JP2002531975 A JP 2002531975A JP 2004525079 A5 JP2004525079 A5 JP 2004525079A5
Authority
JP
Japan
Prior art keywords
cancer
composition
group
anion
metal complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002531975A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004525079A (ja
JP4268801B2 (ja
Filing date
Publication date
Priority claimed from US09/679,932 external-priority patent/US6706759B1/en
Priority claimed from US09/735,205 external-priority patent/US6548540B2/en
Application filed filed Critical
Publication of JP2004525079A publication Critical patent/JP2004525079A/ja
Publication of JP2004525079A5 publication Critical patent/JP2004525079A5/ja
Application granted granted Critical
Publication of JP4268801B2 publication Critical patent/JP4268801B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2002531975A 2000-10-05 2001-10-04 ジチオカルバマート誘導体を使用した癌の治療方法 Expired - Fee Related JP4268801B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/679,932 US6706759B1 (en) 1998-09-08 2000-10-05 Method of treating cancer using dithiocarbamate derivatives
US09/735,205 US6548540B2 (en) 1998-09-08 2000-12-12 Method of treating cancer using dithiocarbamate derivatives
PCT/US2001/031142 WO2002028349A2 (en) 2000-10-05 2001-10-04 Method of treating cancer using dithiocarbamate derivatives

Publications (3)

Publication Number Publication Date
JP2004525079A JP2004525079A (ja) 2004-08-19
JP2004525079A5 true JP2004525079A5 (https=) 2006-01-05
JP4268801B2 JP4268801B2 (ja) 2009-05-27

Family

ID=27102340

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002531975A Expired - Fee Related JP4268801B2 (ja) 2000-10-05 2001-10-04 ジチオカルバマート誘導体を使用した癌の治療方法

Country Status (8)

Country Link
US (3) US6548540B2 (https=)
EP (1) EP1328267B1 (https=)
JP (1) JP4268801B2 (https=)
AT (1) ATE415158T1 (https=)
AU (2) AU9661001A (https=)
CA (1) CA2424761A1 (https=)
DE (1) DE60136730D1 (https=)
WO (1) WO2002028349A2 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7816403B2 (en) * 1998-09-08 2010-10-19 University Of Utah Research Foundation Method of inhibiting ATF/CREB and cancer cell growth and pharmaceutical compositions for same
US6706759B1 (en) * 1998-09-08 2004-03-16 Charlotte-Mecklenburg Hospital Authority Method of treating cancer using dithiocarbamate derivatives
US20050096304A1 (en) * 1998-09-08 2005-05-05 David White Method of treating cancer using dithiocarbamate derivatives
US20060142621A1 (en) * 2003-01-29 2006-06-29 Tiekink Edward R T Bismuth dithiocarbamate compounds and uses thereof
US7638331B2 (en) 2004-01-02 2009-12-29 The Administration of the Tulane Rducation Fund Directed apoptosis in COX-2 overexpressing cancer cells through expression targeted gene delivery
WO2005090299A2 (en) * 2004-03-12 2005-09-29 Wyeth Carbamates as hiv anti-viral agents
IL161899A0 (en) * 2004-05-10 2005-11-20 Hoffman Arnold Kit for treatment of cancer
WO2007139961A1 (en) * 2006-05-25 2007-12-06 The University Of Chicago Methods of reducing cell death following hypoxia / reoxygenation
EP2101567A4 (en) 2007-01-18 2010-04-21 Univ Utah Res Found COMPOSITIONS AND METHODS FOR DETECTING, TREATING OR PREVENTING REDUCED STRESS
JP2011515405A (ja) * 2008-03-17 2011-05-19 ユニバーシティ オブ ユタ リサーチ ファンデーション ジチオカルバメート金属キレートならびにその作製および使用方法
US20100227920A1 (en) * 2008-09-29 2010-09-09 The Regents Of The University Of California Aldehyde dehydrogenase inhibitors as novel depigmenting agents
US8529873B2 (en) 2011-08-24 2013-09-10 Los Alamos National Security, Llc SE-72/AS-72 generator system based on Se extraction/ As reextraction
GB201117051D0 (en) * 2011-10-04 2011-11-16 Uni I Oslo Carbonic anhydrase inhibitors
CN103588687B (zh) * 2012-11-21 2016-07-06 复旦大学附属肿瘤医院 一种一价铜金属配合物及其制备方法和用途
WO2014152207A1 (en) 2013-03-15 2014-09-25 Mylan Laboratories, Inc. Hot melt granulation formulations of poorly water-soluble active agents
US20150266909A1 (en) 2014-03-19 2015-09-24 King Abdulaziz City For Science And Technology Gold(i) complexes with t-butyl phosphine and dialkyl dithiocarbamate ligands
CN103992289B (zh) * 2014-05-22 2016-04-06 河南全宇制药股份有限公司 取代噻唑烷氨荒酸铋配合物及其用途
US10722480B2 (en) 2015-01-06 2020-07-28 Tokyo University Of Science Foundation Agent for controlling cells constituting cancer microenvironment or inflammatory microenvironment
EP3311843A1 (en) * 2016-10-13 2018-04-25 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Compositions comprising dithiocarbamate and cyclodextrin
US10322096B2 (en) 2016-10-26 2019-06-18 Cantex Pharmaceuticals, Inc. Disulfiram and metal salt staggered oral dosing regimen and staggered-release oral unit dosage forms
WO2019010231A1 (en) * 2017-07-05 2019-01-10 Duke University APPARATUS AS TARGETED PRODRUGS FOR PROSTATE CANCER AND METHODS OF MAKING AND USING THE SAME
DK3459526T3 (da) * 2017-09-26 2021-05-25 Palacky Univ In Olomouc Biotilgængelige dithiocarbamat-metalkompleks-nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf
CN108295091A (zh) * 2018-02-26 2018-07-20 广州医科大学 AgDT化合物的应用
WO2019241873A1 (en) * 2018-06-22 2019-12-26 Cuprous Pharmaceuticals Inc. Metal containing products and compositions to induce immunogenic cell death and uses thereof
CA3103432A1 (en) * 2018-06-27 2020-01-02 Children's Medical Center Corporation Compounds for inhibition of inflammation
EP3636285A1 (en) 2018-10-08 2020-04-15 Palacky University, Olomouc Molecular complex assembly particles comprising bis-r1,r2-dithiocarbamate-metal complex and a ligand, method of preparation and use thereof
US10494394B1 (en) 2018-11-29 2019-12-03 King Fahd University Of Petroleum And Minerals Synthesis, x-ray structures and cytotoxic behavior of platinum (II) complexes of dithiocarbamates
CN111349033A (zh) * 2018-12-20 2020-06-30 杜剑平 基于双硫仑结构的衍生物广谱抗肿瘤药物及其制备方法
CN109432072A (zh) * 2018-12-29 2019-03-08 广州中医药大学(广州中医药研究院) 一种双硫仑-金属有机框架复合物及其制备方法和应用
CN110917182A (zh) * 2019-12-30 2020-03-27 广州医科大学 双硫仑在制备防治nlrp3炎症小体相关疾病的药物中的应用
CN112022815B (zh) * 2020-08-19 2022-05-10 四川大学 一种水相制备高Cu(DTC)2载药量抗肿瘤蛋白纳米药物的方法
KR102837369B1 (ko) * 2021-06-18 2025-07-24 고려대학교 산학협력단 타이람과 구리를 유효성분으로 하는 암 예방 또는 치료를 위한 병용 투여용 약학 조성물

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148885A (en) 1973-09-25 1979-04-10 Institut Merieux Immunostimulant medicine
US4581224A (en) 1980-08-08 1986-04-08 Regents Of The University Of Minnesota Inhibition of undesired effect of platinum compounds
US4594238A (en) 1980-08-08 1986-06-10 Regents Of University Of Minnesota Inhibition of undesired effect of platinum compounds
US4426372A (en) 1980-08-08 1984-01-17 Regents Of The University Of Minnesota Inhibition of undesired effects of platinum(II) compounds
US4368223A (en) * 1981-06-01 1983-01-11 Asahi Glass Company, Ltd. Process for preparing nickel layer
US4762705A (en) 1981-11-10 1988-08-09 Adolf W. Schwimmer Cancer therapy with interferon
US4645661A (en) 1984-06-29 1987-02-24 St. Jude Children's Research Hospital Method for alleviating cisplatin-induced nephrotoxicity and dithiocarbamate compounds for effecting same
GB8425006D0 (en) * 1984-10-03 1984-11-07 Efamol Ltd Composition of copper/fatty acids
US4599152A (en) * 1985-05-24 1986-07-08 Albion Laboratories Pure amino acid chelates
US4999347A (en) * 1986-08-28 1991-03-12 Sorenson John R J Analgesic method
EP0348507A4 (en) * 1987-12-23 1990-12-27 Poltav Med Stomatolog Inst Pharmaceutical preparation for individual prophylaxis of venereal diseases and curing urogenital trichomoniasis
US5002755A (en) * 1988-02-18 1991-03-26 Vanderbilt University Method of controlling nephrotoxicity of anti-tumor plaintum compounds
US5035878A (en) 1988-09-12 1991-07-30 University Of Rochester Use of dithiocarbamates to counteract myelosuppression
US5294430A (en) * 1988-09-12 1994-03-15 University Of Rochester Use of dithiocarbamates to treat myelosuppression
US5187193A (en) 1988-09-12 1993-02-16 University Of Rochester Method for stimulating transplanted bone marrow cells
JPH04202139A (ja) 1990-11-30 1992-07-22 Tosoh Corp 血管新生抑制剤
US5206264A (en) * 1991-11-04 1993-04-27 Cypros Pharmaceutical Corporation Use of disulfiram to prevent cardiovascular damage
EP0611306B1 (en) 1991-11-08 1998-07-08 Somatogen, Inc. Hemoglobins as drug delivery agents
US5240914A (en) * 1992-02-03 1993-08-31 Adolph Schwimmer Method and compositions for inhibiting tumor cell metabolism
US5373025A (en) * 1992-02-24 1994-12-13 Olin Corporation Sanitizer for swimming pools, spas, and hot tubs
US5380747A (en) * 1992-10-30 1995-01-10 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5783596A (en) 1992-10-30 1998-07-21 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5807884A (en) 1992-10-30 1998-09-15 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
US5786344A (en) 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
US6469057B1 (en) * 1995-06-02 2002-10-22 Mcw Research Foundation, Inc. Methods for in vivo reduction of free radical levels and compositions useful therefor
US5792787A (en) 1995-06-07 1998-08-11 Emory University Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
GB9515930D0 (en) * 1995-08-03 1995-10-04 Ackers John P Anti-trichomonal compounds
CA2265877A1 (en) * 1996-09-10 1998-03-19 Medinox, Inc. Polydithiocarbamate-containing macromolecules and the use thereof for therapeutic and diagnostic applications
WO1998019676A1 (en) 1996-11-06 1998-05-14 Faiman Morris D Method for treatment of glutamate related disorders
IL122891A0 (en) 1998-01-11 1998-08-16 Yeda Res & Dev Pharmaceutical compositions comprising a thiocarbamate
IL122892A0 (en) * 1998-01-11 1998-08-16 Yeda Res & Dev Pharmaceutical compositions comprising a thiocarbamate
US6589987B2 (en) * 1998-09-08 2003-07-08 Charlotte-Mecklenburg Hospital Authority Method of treating cancer using tetraethyl thiuram disulfide
ES2306595B1 (es) * 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.

Similar Documents

Publication Publication Date Title
JP2004525079A5 (https=)
Alessio Bioinorganic medicinal chemistry
JP2005525345A5 (https=)
CY1109607T1 (el) Παραγωγο εποθιλονης για τη θεραπευτικη αντιμετωπιση του ηπατωματος και αλλων κακοηθων νοσων
JP2010528026A5 (https=)
CA2268321C (en) Use of metal complexes to treat gastrointestinal infections
JP2012509279A5 (https=)
Fricker Medicinal chemistry and pharmacology of gold compounds
FI4225297T3 (fi) Yhdistelmälääkehoito syövän hoidossa
Zhang et al. Synthesis, structure, and in vitro antiproliferative activity of cyclic hypervalent organobismuth (III) chlorides and their triphenylgermylpropionate derivatives
JP2023088996A5 (https=)
JP2021105005A5 (https=)
JP2003508543A5 (https=)
Gaffney et al. Efficacy and patterns of failure for locally advanced cancer of the cervix treated with celebrex (celecoxib) and chemoradiotherapy in RTOG 0128
JP2003505513A5 (https=)
JP2005527487A5 (https=)
CN107184600B (zh) 一种含有无机砷化合物的药物组合物及其应用
CN110960676A (zh) 一种铁取代的二聚硒钨酸纳米团簇及其制备方法和应用
JP2002506855A (ja) 細胞毒性金属キレート剤とその製法及びその使用方法
CA2481602A1 (en) Pharmaceutical composition comprising arsenite for the treatment of malignancy
JP2009525987A (ja) 黒色腫の治療のためのガリウム（ｉｉｉ）錯体の使用
CN117986320A (zh) 一种靶向降解细胞内bcl-3的protac化合物及其制备方法与应用
Deshmukh et al. Therapeutic approaches of nanostructure metallic materials in management of colorectal cancer: Recent advancement
CN113713110B (zh) 一种药物组合物及其应用
Young et al. Adenocarcinoma of the fallopian tube: report of a case with an unusual pattern of metastasis and response to combination chemotherapy