CA2424761A1 - Method of treating cancer using dithiocarbamate derivatives - Google Patents
Method of treating cancer using dithiocarbamate derivatives Download PDFInfo
- Publication number
- CA2424761A1 CA2424761A1 CA002424761A CA2424761A CA2424761A1 CA 2424761 A1 CA2424761 A1 CA 2424761A1 CA 002424761 A CA002424761 A CA 002424761A CA 2424761 A CA2424761 A CA 2424761A CA 2424761 A1 CA2424761 A1 CA 2424761A1
- Authority
- CA
- Canada
- Prior art keywords
- administered
- anion
- dithiocarbamate
- disulfiram
- dithiocarbamate thiolate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Animal Behavior & Ethology (AREA)
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- General Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/679,932 US6706759B1 (en) | 1998-09-08 | 2000-10-05 | Method of treating cancer using dithiocarbamate derivatives |
| US09/679,932 | 2000-10-05 | ||
| US09/735,205 US6548540B2 (en) | 1998-09-08 | 2000-12-12 | Method of treating cancer using dithiocarbamate derivatives |
| US09/735,205 | 2000-12-12 | ||
| PCT/US2001/031142 WO2002028349A2 (en) | 2000-10-05 | 2001-10-04 | Method of treating cancer using dithiocarbamate derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2424761A1 true CA2424761A1 (en) | 2002-04-11 |
Family
ID=27102340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002424761A Abandoned CA2424761A1 (en) | 2000-10-05 | 2001-10-04 | Method of treating cancer using dithiocarbamate derivatives |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6548540B2 (https=) |
| EP (1) | EP1328267B1 (https=) |
| JP (1) | JP4268801B2 (https=) |
| AT (1) | ATE415158T1 (https=) |
| AU (2) | AU9661001A (https=) |
| CA (1) | CA2424761A1 (https=) |
| DE (1) | DE60136730D1 (https=) |
| WO (1) | WO2002028349A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7816403B2 (en) | 1998-09-08 | 2010-10-19 | University Of Utah Research Foundation | Method of inhibiting ATF/CREB and cancer cell growth and pharmaceutical compositions for same |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6706759B1 (en) * | 1998-09-08 | 2004-03-16 | Charlotte-Mecklenburg Hospital Authority | Method of treating cancer using dithiocarbamate derivatives |
| US20050096304A1 (en) * | 1998-09-08 | 2005-05-05 | David White | Method of treating cancer using dithiocarbamate derivatives |
| US20060142621A1 (en) * | 2003-01-29 | 2006-06-29 | Tiekink Edward R T | Bismuth dithiocarbamate compounds and uses thereof |
| US7638331B2 (en) | 2004-01-02 | 2009-12-29 | The Administration of the Tulane Rducation Fund | Directed apoptosis in COX-2 overexpressing cancer cells through expression targeted gene delivery |
| WO2005090299A2 (en) * | 2004-03-12 | 2005-09-29 | Wyeth | Carbamates as hiv anti-viral agents |
| IL161899A0 (en) * | 2004-05-10 | 2005-11-20 | Hoffman Arnold | Kit for treatment of cancer |
| WO2007139961A1 (en) * | 2006-05-25 | 2007-12-06 | The University Of Chicago | Methods of reducing cell death following hypoxia / reoxygenation |
| EP2101567A4 (en) | 2007-01-18 | 2010-04-21 | Univ Utah Res Found | COMPOSITIONS AND METHODS FOR DETECTING, TREATING OR PREVENTING REDUCED STRESS |
| JP2011515405A (ja) * | 2008-03-17 | 2011-05-19 | ユニバーシティ オブ ユタ リサーチ ファンデーション | ジチオカルバメート金属キレートならびにその作製および使用方法 |
| US20100227920A1 (en) * | 2008-09-29 | 2010-09-09 | The Regents Of The University Of California | Aldehyde dehydrogenase inhibitors as novel depigmenting agents |
| US8529873B2 (en) | 2011-08-24 | 2013-09-10 | Los Alamos National Security, Llc | SE-72/AS-72 generator system based on Se extraction/ As reextraction |
| GB201117051D0 (en) * | 2011-10-04 | 2011-11-16 | Uni I Oslo | Carbonic anhydrase inhibitors |
| CN103588687B (zh) * | 2012-11-21 | 2016-07-06 | 复旦大学附属肿瘤医院 | 一种一价铜金属配合物及其制备方法和用途 |
| WO2014152207A1 (en) | 2013-03-15 | 2014-09-25 | Mylan Laboratories, Inc. | Hot melt granulation formulations of poorly water-soluble active agents |
| US20150266909A1 (en) | 2014-03-19 | 2015-09-24 | King Abdulaziz City For Science And Technology | Gold(i) complexes with t-butyl phosphine and dialkyl dithiocarbamate ligands |
| CN103992289B (zh) * | 2014-05-22 | 2016-04-06 | 河南全宇制药股份有限公司 | 取代噻唑烷氨荒酸铋配合物及其用途 |
| US10722480B2 (en) | 2015-01-06 | 2020-07-28 | Tokyo University Of Science Foundation | Agent for controlling cells constituting cancer microenvironment or inflammatory microenvironment |
| EP3311843A1 (en) * | 2016-10-13 | 2018-04-25 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Compositions comprising dithiocarbamate and cyclodextrin |
| US10322096B2 (en) | 2016-10-26 | 2019-06-18 | Cantex Pharmaceuticals, Inc. | Disulfiram and metal salt staggered oral dosing regimen and staggered-release oral unit dosage forms |
| WO2019010231A1 (en) * | 2017-07-05 | 2019-01-10 | Duke University | APPARATUS AS TARGETED PRODRUGS FOR PROSTATE CANCER AND METHODS OF MAKING AND USING THE SAME |
| DK3459526T3 (da) * | 2017-09-26 | 2021-05-25 | Palacky Univ In Olomouc | Biotilgængelige dithiocarbamat-metalkompleks-nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf |
| CN108295091A (zh) * | 2018-02-26 | 2018-07-20 | 广州医科大学 | AgDT化合物的应用 |
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| CA3103432A1 (en) * | 2018-06-27 | 2020-01-02 | Children's Medical Center Corporation | Compounds for inhibition of inflammation |
| EP3636285A1 (en) | 2018-10-08 | 2020-04-15 | Palacky University, Olomouc | Molecular complex assembly particles comprising bis-r1,r2-dithiocarbamate-metal complex and a ligand, method of preparation and use thereof |
| US10494394B1 (en) | 2018-11-29 | 2019-12-03 | King Fahd University Of Petroleum And Minerals | Synthesis, x-ray structures and cytotoxic behavior of platinum (II) complexes of dithiocarbamates |
| CN111349033A (zh) * | 2018-12-20 | 2020-06-30 | 杜剑平 | 基于双硫仑结构的衍生物广谱抗肿瘤药物及其制备方法 |
| CN109432072A (zh) * | 2018-12-29 | 2019-03-08 | 广州中医药大学(广州中医药研究院) | 一种双硫仑-金属有机框架复合物及其制备方法和应用 |
| CN110917182A (zh) * | 2019-12-30 | 2020-03-27 | 广州医科大学 | 双硫仑在制备防治nlrp3炎症小体相关疾病的药物中的应用 |
| CN112022815B (zh) * | 2020-08-19 | 2022-05-10 | 四川大学 | 一种水相制备高Cu(DTC)2载药量抗肿瘤蛋白纳米药物的方法 |
| KR102837369B1 (ko) * | 2021-06-18 | 2025-07-24 | 고려대학교 산학협력단 | 타이람과 구리를 유효성분으로 하는 암 예방 또는 치료를 위한 병용 투여용 약학 조성물 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7816403B2 (en) | 1998-09-08 | 2010-10-19 | University Of Utah Research Foundation | Method of inhibiting ATF/CREB and cancer cell growth and pharmaceutical compositions for same |
Also Published As
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| EP1328267A4 (en) | 2006-03-22 |
| US20070232692A1 (en) | 2007-10-04 |
| EP1328267B1 (en) | 2008-11-26 |
| US20030229064A1 (en) | 2003-12-11 |
| AU9661001A (en) | 2002-04-15 |
| DE60136730D1 (de) | 2009-01-08 |
| US20010016600A1 (en) | 2001-08-23 |
| EP1328267A2 (en) | 2003-07-23 |
| AU2001296610B2 (en) | 2006-06-29 |
| WO2002028349A2 (en) | 2002-04-11 |
| US6548540B2 (en) | 2003-04-15 |
| WO2002028349A3 (en) | 2002-07-11 |
| ATE415158T1 (de) | 2008-12-15 |
| JP2004525079A (ja) | 2004-08-19 |
| JP4268801B2 (ja) | 2009-05-27 |
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| FZDE | Discontinued |