JP2004518624A - Ｈｉｖ−１感染を阻害する組成物および方法 - Google Patents

Ｈｉｖ−１感染を阻害する組成物および方法 Download PDF

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JP2004518624A
JP2004518624A JP2002526332A JP2002526332A JP2004518624A JP 2004518624 A JP2004518624 A JP 2004518624A JP 2002526332 A JP2002526332 A JP 2002526332A JP 2002526332 A JP2002526332 A JP 2002526332A JP 2004518624 A JP2004518624 A JP 2004518624A
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hiv
composition
cells
fusion
antibody
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JP2004518624A5 (enExample
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オルソン、ウィリアム・シー
マドン、ポール・ジェイ
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プロジェニクス・ファーマスーティカルズ・インコーポレイテッド
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Priority claimed from PCT/US2001/002633 external-priority patent/WO2001055439A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2002526332A 2000-09-15 2001-09-14 Ｈｉｖ−１感染を阻害する組成物および方法 Withdrawn JP2004518624A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66321900A 2000-09-15 2000-09-15
PCT/US2001/002633 WO2001055439A1 (en) 2000-01-28 2001-01-26 Compositions and methods for inhibition of hiv-1 infection
US26673801P 2001-02-06 2001-02-06
US09/912,824 US7138119B2 (en) 2000-09-15 2001-07-25 Compositions and methods for inhibition of HIV-1 infection
PCT/US2001/028756 WO2002022077A2 (en) 2000-09-15 2001-09-14 Compositions and methods for inhibition of hiv-1 infection

Publications (2)

Publication Number Publication Date
JP2004518624A true JP2004518624A (ja) 2004-06-24
JP2004518624A5 JP2004518624A5 (enExample) 2008-11-06

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JP2002526332A Withdrawn JP2004518624A (ja) 2000-09-15 2001-09-14 Ｈｉｖ−１感染を阻害する組成物および方法

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US (2) US7138119B2 (enExample)
EP (1) EP1322332A4 (enExample)
JP (1) JP2004518624A (enExample)
AU (2) AU2001290925C1 (enExample)
CA (1) CA2422275A1 (enExample)
WO (1) WO2002022077A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012065055A3 (en) * 2010-11-12 2012-07-12 The Rockefeller University Fusion proteins for hiv therapy
JP2017501986A (ja) * 2013-12-02 2017-01-19 アーロン ダイアモンド エイズ リサーチ センター ネイティブな構成を有する二重特異性抗体を使用した細胞レセプターアンカリングによる改善されたｈｉｖ−１中和抗体の効力及び幅
JP2019521639A (ja) * 2015-11-21 2019-08-08 フンダシオ プリバダ インスティトゥト デ レセルカ デラ シダ−カイサＦｕｎｄａｃｉｏ Ｐｒｉｖａｄａ Ｉｎｓｔｉｔｕｔ Ｄｅ Ｒｅｃｅｒｃａ Ｄｅ Ｌａ Ｓｉｄａ−Ｃａｉｘａ 抗ウイルスおよび免疫調節の二重活性を有するｈｉｖ抗体誘導体
JP2020519309A (ja) * 2017-05-10 2020-07-02 アルバジュナ・セラピューティクス・エセ・エレ 高い二重のＨＩＶ抗ウイルス及び免疫調節活性を有するＦｃ融合タンパク質誘導体
US12098187B2 (en) 2013-12-02 2024-09-24 The Trustees Of Columbia University In The City Of New York Bispecific HIV-1-neutralizing antibodies

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012065055A3 (en) * 2010-11-12 2012-07-12 The Rockefeller University Fusion proteins for hiv therapy
US8637024B2 (en) 2010-11-12 2014-01-28 The Rockefeller University Fusion antibodies for HIV therapy
JP2017501986A (ja) * 2013-12-02 2017-01-19 アーロン ダイアモンド エイズ リサーチ センター ネイティブな構成を有する二重特異性抗体を使用した細胞レセプターアンカリングによる改善されたｈｉｖ−１中和抗体の効力及び幅
JP2020002174A (ja) * 2013-12-02 2020-01-09 アーロン ダイアモンド エイズ リサーチ センター 二重特異性ｈｉｖ−１中和抗体
US12098187B2 (en) 2013-12-02 2024-09-24 The Trustees Of Columbia University In The City Of New York Bispecific HIV-1-neutralizing antibodies
JP2019521639A (ja) * 2015-11-21 2019-08-08 フンダシオ プリバダ インスティトゥト デ レセルカ デラ シダ−カイサＦｕｎｄａｃｉｏ Ｐｒｉｖａｄａ Ｉｎｓｔｉｔｕｔ Ｄｅ Ｒｅｃｅｒｃａ Ｄｅ Ｌａ Ｓｉｄａ−Ｃａｉｘａ 抗ウイルスおよび免疫調節の二重活性を有するｈｉｖ抗体誘導体
JP2022008978A (ja) * 2015-11-21 2022-01-14 フンダシオ プリバダ インスティトゥト デ レセルカ デラ シダ－カイサ 抗ウイルスおよび免疫調節の二重活性を有するｈｉｖ抗体誘導体
JP6991138B2 (ja) 2015-11-21 2022-02-03 フンダシオ プリバダ インスティトゥト デ レセルカ デラ シダ－カイサ 抗ウイルスおよび免疫調節の二重活性を有するｈｉｖ抗体誘導体
US11866479B2 (en) 2015-11-21 2024-01-09 Fundació Privada Institute De Recera De La Sida-Caixa HIV antibody derivatives with dual antiviral and immunomodulatory activities from CD4 and GP41
JP2020519309A (ja) * 2017-05-10 2020-07-02 アルバジュナ・セラピューティクス・エセ・エレ 高い二重のＨＩＶ抗ウイルス及び免疫調節活性を有するＦｃ融合タンパク質誘導体
JP2023078339A (ja) * 2017-05-10 2023-06-06 アルバジュナ・セラピューティクス・エセ・エレ 高い二重のＨＩＶ抗ウイルス及び免疫調節活性を有するＦｃ融合タンパク質誘導体

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AU9092501A (en) 2002-03-26
EP1322332A4 (en) 2006-06-21
WO2002022077A3 (en) 2002-06-20
EP1322332A2 (en) 2003-07-02
WO2002022077A2 (en) 2002-03-21
US7736649B2 (en) 2010-06-15
US20020106374A1 (en) 2002-08-08
CA2422275A1 (en) 2002-03-21
US20070020280A1 (en) 2007-01-25
AU2001290925C1 (en) 2009-01-22
US7138119B2 (en) 2006-11-21
AU2001290925B2 (en) 2006-07-13

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