JP2004517075A5 - - Google Patents
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- Publication number
- JP2004517075A5 JP2004517075A5 JP2002544437A JP2002544437A JP2004517075A5 JP 2004517075 A5 JP2004517075 A5 JP 2004517075A5 JP 2002544437 A JP2002544437 A JP 2002544437A JP 2002544437 A JP2002544437 A JP 2002544437A JP 2004517075 A5 JP2004517075 A5 JP 2004517075A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24456700P | 2000-10-31 | 2000-10-31 | |
| GBGB0117075.2A GB0117075D0 (en) | 2000-10-31 | 2001-07-13 | Acyl and sulfonyl derivatives of 6, 9-distributed 2-(trans-1, 4-diaminocyclohexyl)-purines and their use as antiproliferative agents |
| PCT/US2001/044835 WO2002042303A2 (en) | 2000-10-31 | 2001-10-31 | Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004517075A JP2004517075A (ja) | 2004-06-10 |
| JP2004517075A5 true JP2004517075A5 (ja) | 2005-12-22 |
| JP4348081B2 JP4348081B2 (ja) | 2009-10-21 |
Family
ID=26246308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002544437A Expired - Lifetime JP4348081B2 (ja) | 2000-10-31 | 2001-10-31 | ６，９−二置換２−（トランス−１，４−ジアミノシクロヘキシル）−プリンのアシル及びスルホニル誘導体及び抗増殖剤としてのその使用 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1377579B1 (ja) |
| JP (1) | JP4348081B2 (ja) |
| AT (1) | ATE426603T1 (ja) |
| AU (2) | AU3938802A (ja) |
| BR (1) | BR0115080A (ja) |
| CA (1) | CA2427338C (ja) |
| DE (1) | DE60138140D1 (ja) |
| DK (1) | DK1377579T3 (ja) |
| ES (1) | ES2324763T3 (ja) |
| IL (1) | IL155590A0 (ja) |
| MX (1) | MXPA03003774A (ja) |
| NO (1) | NO20031939L (ja) |
| NZ (1) | NZ525264A (ja) |
| WO (1) | WO2002042303A2 (ja) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7563810B2 (en) * | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| FR2851248B1 (fr) * | 2003-02-18 | 2005-04-08 | Aventis Pharma Sa | Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation |
| CA2525207A1 (en) * | 2003-06-12 | 2004-12-23 | Novo Nordisk A/S | Substituted piperidine carbamates for use as inhibitors of hormone sensitive lipase |
| US8389533B2 (en) * | 2008-04-07 | 2013-03-05 | Amgen Inc. | Gem-disubstituted and spirocyclic amino pyridines/pyrimidines as cell cycle inhibitors |
| US9180127B2 (en) | 2009-12-29 | 2015-11-10 | Dana-Farber Cancer Institute, Inc. | Type II Raf kinase inhibitors |
| AU2012340200B2 (en) | 2011-11-17 | 2017-10-12 | Dana-Farber Cancer Institute, Inc. | Inhibitors of c-Jun-N-Terminal Kinase (JNK) |
| JP6491202B2 (ja) | 2013-10-18 | 2019-03-27 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | サイクリン依存性キナーゼ７（ｃｄｋ７）の多環阻害剤 |
| EP3236959A4 (en) | 2014-12-23 | 2018-04-25 | Dana Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 7 (cdk7) |
| CA2978518C (en) * | 2015-03-27 | 2023-11-21 | Nathanael S. Gray | Inhibitors of cyclin-dependent kinases |
| CA2996978A1 (en) | 2015-09-09 | 2017-03-16 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinases |
| US11066404B2 (en) | 2018-10-11 | 2021-07-20 | Incyte Corporation | Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors |
| US11384083B2 (en) | 2019-02-15 | 2022-07-12 | Incyte Corporation | Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors |
| WO2020180959A1 (en) | 2019-03-05 | 2020-09-10 | Incyte Corporation | Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors |
| WO2020205560A1 (en) | 2019-03-29 | 2020-10-08 | Incyte Corporation | Sulfonylamide compounds as cdk2 inhibitors |
| WO2020223469A1 (en) | 2019-05-01 | 2020-11-05 | Incyte Corporation | N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer |
| US11447494B2 (en) | 2019-05-01 | 2022-09-20 | Incyte Corporation | Tricyclic amine compounds as CDK2 inhibitors |
| AR119765A1 (es) | 2019-08-14 | 2022-01-12 | Incyte Corp | Compuestos de imidazolil pirimidinilamina como inhibidores de cdk2 |
| MX2022004390A (es) | 2019-10-11 | 2022-08-08 | Incyte Corp | Aminas biciclicas como inhibidores de la cinasa dependiente de ciclina 2 (cdk2). |
| US11981671B2 (en) | 2021-06-21 | 2024-05-14 | Incyte Corporation | Bicyclic pyrazolyl amines as CDK2 inhibitors |
| US11976073B2 (en) | 2021-12-10 | 2024-05-07 | Incyte Corporation | Bicyclic amines as CDK2 inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6479487B1 (en) * | 1998-02-26 | 2002-11-12 | Aventis Pharmaceuticals Inc. | 6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines |
| HUP0100931A3 (en) * | 1998-02-26 | 2002-08-28 | Aventis Pharma Inc | 6,9-disubstituted 2-[trans-(-aminocyclohexyl)amino]purines and pharmaceutical compositions containing them |
| FR2793794B1 (fr) * | 1999-05-21 | 2001-07-27 | Hoechst Marion Roussel Inc | Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation |
| WO2001044260A2 (en) * | 1999-12-17 | 2001-06-21 | Ariad Pharmaceuticals, Inc. | Novel purines |
| EP1244668B1 (en) * | 2000-01-07 | 2006-04-05 | Universitaire Instelling Antwerpen | Purine derivatives, process for their preparation and use thereof |
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2001
- 2001-10-31 ES ES01987144T patent/ES2324763T3/es not_active Expired - Lifetime
- 2001-10-31 BR BR0115080-4A patent/BR0115080A/pt not_active Application Discontinuation
- 2001-10-31 AT AT01987144T patent/ATE426603T1/de active
- 2001-10-31 AU AU3938802A patent/AU3938802A/xx active Pending
- 2001-10-31 IL IL15559001A patent/IL155590A0/xx unknown
- 2001-10-31 EP EP01987144A patent/EP1377579B1/en not_active Expired - Lifetime
- 2001-10-31 DK DK01987144T patent/DK1377579T3/da active
- 2001-10-31 AU AU2002239388A patent/AU2002239388B2/en not_active Expired
- 2001-10-31 NZ NZ525264A patent/NZ525264A/en not_active IP Right Cessation
- 2001-10-31 DE DE60138140T patent/DE60138140D1/de not_active Expired - Lifetime
- 2001-10-31 JP JP2002544437A patent/JP4348081B2/ja not_active Expired - Lifetime
- 2001-10-31 MX MXPA03003774A patent/MXPA03003774A/es active IP Right Grant
- 2001-10-31 WO PCT/US2001/044835 patent/WO2002042303A2/en active Application Filing
- 2001-10-31 CA CA002427338A patent/CA2427338C/en not_active Expired - Lifetime
-
2003
- 2003-04-29 NO NO20031939A patent/NO20031939L/no not_active Application Discontinuation