JP2004513631A - ヒト精巣特異的セリン／スレオニンキナーゼ - Google Patents

ヒト精巣特異的セリン／スレオニンキナーゼ Download PDF

Info

Publication number
JP2004513631A
JP2004513631A JP2002542049A JP2002542049A JP2004513631A JP 2004513631 A JP2004513631 A JP 2004513631A JP 2002542049 A JP2002542049 A JP 2002542049A JP 2002542049 A JP2002542049 A JP 2002542049A JP 2004513631 A JP2004513631 A JP 2004513631A
Authority
JP
Japan
Prior art keywords
seq
tssk
kinase
amino acid
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002542049A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004513631A5 (enExample
Inventor
グレゴリー・エス・コーフ
ジョン・シー・ハー
パブロ・ビスコンティ
ハオ・ジョンリン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UVA Licensing and Ventures Group
Original Assignee
University of Virginia Patent Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Virginia Patent Foundation filed Critical University of Virginia Patent Foundation
Publication of JP2004513631A publication Critical patent/JP2004513631A/ja
Publication of JP2004513631A5 publication Critical patent/JP2004513631A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2002542049A 2000-11-09 2001-11-09 ヒト精巣特異的セリン／スレオニンキナーゼ Pending JP2004513631A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24693900P 2000-11-09 2000-11-09
US26492101P 2001-01-30 2001-01-30
PCT/US2001/046803 WO2002038732A2 (en) 2000-11-09 2001-11-09 Human testis specific serine/threonine kinase

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2003184906A Division JP2004135653A (ja) 2000-11-09 2003-06-27 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2009035474A Division JP2009148281A (ja) 2000-11-09 2009-02-18 ヒト精巣特異的セリン／スレオニンキナーゼ

Publications (2)

Publication Number Publication Date
JP2004513631A true JP2004513631A (ja) 2004-05-13
JP2004513631A5 JP2004513631A5 (enExample) 2005-04-21

Family

ID=26938336

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2002542049A Pending JP2004513631A (ja) 2000-11-09 2001-11-09 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2003184906A Withdrawn JP2004135653A (ja) 2000-11-09 2003-06-27 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2007174924A Pending JP2007306930A (ja) 2000-11-09 2007-07-03 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2009035474A Pending JP2009148281A (ja) 2000-11-09 2009-02-18 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2009216891A Pending JP2010029197A (ja) 2000-11-09 2009-09-18 ヒト精巣特異的セリン／スレオニンキナーゼ

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2003184906A Withdrawn JP2004135653A (ja) 2000-11-09 2003-06-27 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2007174924A Pending JP2007306930A (ja) 2000-11-09 2007-07-03 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2009035474A Pending JP2009148281A (ja) 2000-11-09 2009-02-18 ヒト精巣特異的セリン／スレオニンキナーゼ
JP2009216891A Pending JP2010029197A (ja) 2000-11-09 2009-09-18 ヒト精巣特異的セリン／スレオニンキナーゼ

Country Status (8)

Country Link
US (2) US7129057B2 (enExample)
EP (1) EP1339866B1 (enExample)
JP (5) JP2004513631A (enExample)
AT (2) ATE477332T1 (enExample)
AU (4) AU2002237699B9 (enExample)
DE (2) DE60142804D1 (enExample)
IL (4) IL155800A0 (enExample)
WO (1) WO2002038732A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008067649A (ja) * 2006-09-14 2008-03-27 Osaka Univ 妊孕性診断キット、変異検出方法、ポリヌクレオチド、及びポリペプチド

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1278864A2 (en) * 2000-05-12 2003-01-29 MERCK PATENT GmbH Serine-threonine kinase-3
US20050032146A1 (en) * 2003-08-07 2005-02-10 Herr John C. Tssk4: a human testis specific serine/threonine kinase
US20080274117A1 (en) * 2004-09-30 2008-11-06 Herr John C Validation of Tssk Family Members and Tsks as Male Contraceptive Targets
CN115976033B (zh) * 2022-12-14 2024-05-17 西南大学 瓜实蝇tssk1和tssk3基因及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003501038A (ja) * 1999-05-28 2003-01-14 スージェン・インコーポレーテッド 蛋白質キナーゼ
AU2292301A (en) * 1999-12-23 2001-07-03 Incyte Genomics, Inc. Human kinases
US20040048249A1 (en) * 2000-01-21 2004-03-11 Tang Y. Tom Novel nucleic acids and secreted polypeptides
CA2399776A1 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2001083768A2 (en) * 2000-05-05 2001-11-08 Merck Patent Gmbh Serine-threonine kinase
US6482935B1 (en) * 2000-05-24 2002-11-19 Applera Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
WO2002068649A2 (en) * 2001-01-31 2002-09-06 Curagen Corporation Proteins and nucleic acids encoding same
US20030211093A1 (en) * 2001-07-20 2003-11-13 Henry Yue Human kinases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008067649A (ja) * 2006-09-14 2008-03-27 Osaka Univ 妊孕性診断キット、変異検出方法、ポリヌクレオチド、及びポリペプチド

Also Published As

Publication number Publication date
AU2006202059A2 (en) 2006-06-15
DE60142804D1 (de) 2010-09-23
ATE479771T1 (de) 2010-09-15
DE60142984D1 (de) 2010-10-14
JP2004135653A (ja) 2004-05-13
JP2007306930A (ja) 2007-11-29
AU3769902A (en) 2002-05-21
AU2006202059B2 (en) 2009-01-08
US7129057B2 (en) 2006-10-31
JP2009148281A (ja) 2009-07-09
JP2010029197A (ja) 2010-02-12
EP1339866B1 (en) 2010-09-01
AU2006202059A1 (en) 2006-06-15
EP1339866A2 (en) 2003-09-03
US6946275B2 (en) 2005-09-20
IL155801A (en) 2009-12-24
EP1339866A4 (en) 2006-10-25
IL155801A0 (en) 2003-12-23
AU2002237699B2 (en) 2006-05-25
US20040030112A1 (en) 2004-02-12
IL155800A (en) 2009-09-01
WO2002038732A2 (en) 2002-05-16
AU2006202059C1 (en) 2009-06-11
ATE477332T1 (de) 2010-08-15
US20030211563A1 (en) 2003-11-13
IL155800A0 (en) 2003-12-23
AU2002237699B9 (en) 2006-06-29
AU2003204266B2 (en) 2006-06-15
WO2002038732A3 (en) 2002-12-05

Similar Documents

Publication Publication Date Title
JP2010029197A (ja) ヒト精巣特異的セリン／スレオニンキナーゼ
CA2270911A1 (en) Mammalian chk1 effector cell-cycle checkpoint protein kinase materials and methods
US20020064849A1 (en) Human soluble testicular adenylyl cyclase
Osada et al. Subcellular localization and protein interaction of the human LIMK2 gene expressing alternative transcripts with tissue-specific regulation
US6511825B1 (en) Cell signaling polypeptides and nucleic acids
AU2002237699A1 (en) Human testis specific serine/threonine kinase
EP1443117B1 (en) Human testis specific serine/threonine kinase
AU2006218336B2 (en) Human testis specific serine/threonine kinase
US20050032146A1 (en) Tssk4: a human testis specific serine/threonine kinase
JPH10117788A (ja) ヒト・ｍｙｔ−１キナーゼクローン
WO1998048020A2 (en) Mammalian ubiquitin-isopeptidases that control cell proliferation
US20080274117A1 (en) Validation of Tssk Family Members and Tsks as Male Contraceptive Targets
EP1162460A1 (en) Mammalian Suv39h2 proteins and isolated DNA molecules encoding them
JP2001503994A (ja) チロシンリン酸化切断溝関連タンパク質（ｐｓｔｐｉｐ）
JP2003524379A (ja) 環状ヌクレオチド関連タンパク質
US20030054385A1 (en) Human ubiquitin-conjugating enzymes
JP2001518794A (ja) ヒトｇｔｐ結合タンパク質
US20030045699A1 (en) Membrane receptors for steroids and sterols
Nayak A segment of mouse 16 contains a cluster of genes expressed in the developing brain and reproductive system
JPWO1999033961A1 (ja) 新規な燐酸化酵素
WO2001070779A1 (fr) Nouveau polypeptide, proteine humaine 12 de type cdc4, et polynucleotide codant pour ce polypeptide
JPH11225775A (ja) アダプタータンパク質ファミリーのメンバーであるヒトｐ１０１

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060207

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20060508

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20060515

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060807

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060926

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20061215

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20061222

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070326

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20070326

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20081021