JP2004511522A5 - - Google Patents
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- Publication number
- JP2004511522A5 JP2004511522A5 JP2002535668A JP2002535668A JP2004511522A5 JP 2004511522 A5 JP2004511522 A5 JP 2004511522A5 JP 2002535668 A JP2002535668 A JP 2002535668A JP 2002535668 A JP2002535668 A JP 2002535668A JP 2004511522 A5 JP2004511522 A5 JP 2004511522A5
- Authority
- JP
- Japan
- Prior art keywords
- hormone
- cancer
- dependent
- antiprogestin
- meningioma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000001419 dependent effect Effects 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010014733 Endometrial cancer Diseases 0.000 description 1
- 206010014759 Endometrial neoplasm Diseases 0.000 description 1
- 206010033128 Ovarian cancer Diseases 0.000 description 1
- 206010061535 Ovarian neoplasm Diseases 0.000 description 1
- 206010035226 Plasma cell myeloma Diseases 0.000 description 1
- 230000002513 anti-ovulatory effect Effects 0.000 description 1
- 230000000708 anti-progestin effect Effects 0.000 description 1
- 239000003418 antiprogestin Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 108091008039 hormone receptors Proteins 0.000 description 1
- 208000000509 infertility Diseases 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 206010027191 meningioma Diseases 0.000 description 1
- 201000000050 myeloid neoplasm Diseases 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
Description
本発明のおける抗黄体ホルモン（I）の医薬的に許容できる誘導体又は類似体は、例えばWO98/34947号に開示される発明の化合物のいずれか１つを包含することができる。
本発明における用語“ホルモン−依存性疾病”とは、乳癌、卵巣癌、子宮内膜癌、骨髄腫、無排卵不妊症、髄膜腫、すなわちホルモン受容体及び/又はホルモン−依存性経路の存在に実質的に起因するか又はその存在により影響される疾病を包含するが、但しそれらだけには限定されない。
本発明における用語“ホルモン−依存性疾病”とは、乳癌、卵巣癌、子宮内膜癌、骨髄腫、無排卵不妊症、髄膜腫、すなわちホルモン受容体及び/又はホルモン−依存性経路の存在に実質的に起因するか又はその存在により影響される疾病を包含するが、但しそれらだけには限定されない。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24099800P | 2000-10-18 | 2000-10-18 | |
| EP00250341 | 2000-10-18 | ||
| PCT/EP2001/012005 WO2002032430A1 (en) | 2000-10-18 | 2001-10-17 | Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009284779A Division JP2010077158A (ja) | 2000-10-18 | 2009-12-16 | ホルモン−依存性疾病の予防及び処理のための抗黄体ホルモンの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004511522A JP2004511522A (ja) | 2004-04-15 |
| JP2004511522A5 true JP2004511522A5 (ja) | 2009-02-19 |
Family
ID=26072951
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002535668A Ceased JP2004511522A (ja) | 2000-10-18 | 2001-10-17 | ホルモン−依存性疾病の予防及び処理のための抗黄体ホルモンの使用 |
| JP2009284779A Ceased JP2010077158A (ja) | 2000-10-18 | 2009-12-16 | ホルモン−依存性疾病の予防及び処理のための抗黄体ホルモンの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009284779A Ceased JP2010077158A (ja) | 2000-10-18 | 2009-12-16 | ホルモン−依存性疾病の予防及び処理のための抗黄体ホルモンの使用 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7378406B2 (ja) |
| EP (1) | EP1328276B1 (ja) |
| JP (2) | JP2004511522A (ja) |
| KR (1) | KR100632908B1 (ja) |
| CN (1) | CN1512886A (ja) |
| AT (1) | ATE310522T1 (ja) |
| AU (2) | AU1824302A (ja) |
| BG (1) | BG107743A (ja) |
| BR (1) | BR0114665A (ja) |
| CA (1) | CA2423017C (ja) |
| CY (1) | CY1104981T1 (ja) |
| CZ (1) | CZ299942B6 (ja) |
| DE (1) | DE60115274T2 (ja) |
| DK (1) | DK1328276T3 (ja) |
| EE (1) | EE05259B1 (ja) |
| ES (1) | ES2253443T3 (ja) |
| HR (1) | HRP20030387A2 (ja) |
| HU (1) | HUP0301460A3 (ja) |
| IL (2) | IL154975A0 (ja) |
| MX (1) | MXPA03002954A (ja) |
| NO (1) | NO20031740L (ja) |
| NZ (1) | NZ538346A (ja) |
| PL (1) | PL360151A1 (ja) |
| SI (1) | SI1328276T1 (ja) |
| SK (1) | SK287124B6 (ja) |
| WO (1) | WO2002032430A1 (ja) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY27301A1 (es) * | 2001-05-25 | 2003-02-28 | Schering Ag | Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata |
| DE10159217A1 (de) | 2001-11-27 | 2003-06-05 | Schering Ag | 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate |
| US20040242551A1 (en) * | 2003-05-28 | 2004-12-02 | Schering Ag | Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases |
| US9517240B2 (en) * | 2006-09-26 | 2016-12-13 | The Regents Of The University Of California | Methods and compositions for cancer prevention and treatment |
| CA2683809A1 (en) * | 2007-04-23 | 2008-10-30 | Bayer Schering Pharma Aktiengesellschaft | Progesterone-receptor antagonist for use in brca alone or as combination with antiestrogen |
| US20080268041A1 (en) * | 2007-04-23 | 2008-10-30 | Jens Hoffmann | Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases |
| US20080261929A1 (en) * | 2007-04-23 | 2008-10-23 | Jens Hoffmann | Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases |
| TWI539953B (zh) * | 2008-04-28 | 2016-07-01 | 瑞波若斯治療學公司 | 用於治療乳癌之組成物和方法 |
| TWI477276B (zh) * | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
| DE102009034368A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102009034362A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102009034367A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
| DE102009034366A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102009034526A1 (de) | 2009-07-21 | 2011-02-10 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
| DE102009034525A1 (de) | 2009-07-21 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102010007719A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
| DE102010007722A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
| UA110030C2 (uk) * | 2010-03-22 | 2015-11-10 | Спосіб лікування ендометріозу або міоми матки і лікарська форма для щоденного введення на слизову піхви жінки | |
| BR112014029131B1 (pt) | 2012-05-31 | 2021-03-09 | Allergan Pharmaceuticals International Limited | cápsula de mucoadesivo |
| CN104755087A (zh) | 2012-11-02 | 2015-07-01 | 利普生物药剂公司 | 治疗孕酮依赖性病况的方法和组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3733478A1 (de) * | 1987-10-01 | 1989-04-13 | Schering Ag | Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore |
| DE19706061A1 (de) * | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
-
2001
- 2001-10-17 AT AT01987668T patent/ATE310522T1/de not_active IP Right Cessation
- 2001-10-17 SK SK474-2003A patent/SK287124B6/sk not_active IP Right Cessation
- 2001-10-17 US US10/399,320 patent/US7378406B2/en not_active Expired - Fee Related
- 2001-10-17 EP EP01987668A patent/EP1328276B1/en not_active Expired - Lifetime
- 2001-10-17 JP JP2002535668A patent/JP2004511522A/ja not_active Ceased
- 2001-10-17 BR BR0114665-3A patent/BR0114665A/pt not_active Application Discontinuation
- 2001-10-17 EE EEP200300155A patent/EE05259B1/xx not_active IP Right Cessation
- 2001-10-17 PL PL36015101A patent/PL360151A1/xx not_active Application Discontinuation
- 2001-10-17 NZ NZ538346A patent/NZ538346A/en unknown
- 2001-10-17 DE DE60115274T patent/DE60115274T2/de not_active Expired - Lifetime
- 2001-10-17 ES ES01987668T patent/ES2253443T3/es not_active Expired - Lifetime
- 2001-10-17 CZ CZ20031072A patent/CZ299942B6/cs not_active IP Right Cessation
- 2001-10-17 CN CNA018175686A patent/CN1512886A/zh active Pending
- 2001-10-17 HU HU0301460A patent/HUP0301460A3/hu unknown
- 2001-10-17 IL IL15497501A patent/IL154975A0/xx active IP Right Grant
- 2001-10-17 SI SI200130486T patent/SI1328276T1/sl unknown
- 2001-10-17 AU AU1824302A patent/AU1824302A/xx active Pending
- 2001-10-17 WO PCT/EP2001/012005 patent/WO2002032430A1/en active IP Right Grant
- 2001-10-17 AU AU2002218243A patent/AU2002218243B2/en not_active Ceased
- 2001-10-17 DK DK01987668T patent/DK1328276T3/da active
- 2001-10-17 CA CA002423017A patent/CA2423017C/en not_active Expired - Fee Related
- 2001-10-17 KR KR1020037005359A patent/KR100632908B1/ko not_active IP Right Cessation
- 2001-10-17 MX MXPA03002954A patent/MXPA03002954A/es active IP Right Grant
-
2003
- 2003-03-18 IL IL154975A patent/IL154975A/en not_active IP Right Cessation
- 2003-04-15 NO NO20031740A patent/NO20031740L/no not_active Application Discontinuation
- 2003-04-18 BG BG107743A patent/BG107743A/bg unknown
- 2003-05-14 HR HR20030387A patent/HRP20030387A2/xx not_active Application Discontinuation
-
2006
- 2006-02-22 CY CY20061100251T patent/CY1104981T1/el unknown
-
2009
- 2009-12-16 JP JP2009284779A patent/JP2010077158A/ja not_active Ceased
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