DK1328276T3 - Anvendelse af antiprogestiner til profylakse og behandling af hormonafhængige sygdomme - Google Patents

Anvendelse af antiprogestiner til profylakse og behandling af hormonafhængige sygdomme

Info

Publication number
DK1328276T3
DK1328276T3 DK01987668T DK01987668T DK1328276T3 DK 1328276 T3 DK1328276 T3 DK 1328276T3 DK 01987668 T DK01987668 T DK 01987668T DK 01987668 T DK01987668 T DK 01987668T DK 1328276 T3 DK1328276 T3 DK 1328276T3
Authority
DK
Denmark
Prior art keywords
antiprogestins
hormone
prophylaxis
treatment
dependent diseases
Prior art date
Application number
DK01987668T
Other languages
English (en)
Inventor
Jens Hoffmann
Rosemarie Lichtner
Gerhard Siemeister
Martin Schneider
Ulrike Fuhrmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK1328276T3 publication Critical patent/DK1328276T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
DK01987668T 2000-10-18 2001-10-17 Anvendelse af antiprogestiner til profylakse og behandling af hormonafhængige sygdomme DK1328276T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24099800P 2000-10-18 2000-10-18
EP00250341 2000-10-18

Publications (1)

Publication Number Publication Date
DK1328276T3 true DK1328276T3 (da) 2006-04-03

Family

ID=26072951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01987668T DK1328276T3 (da) 2000-10-18 2001-10-17 Anvendelse af antiprogestiner til profylakse og behandling af hormonafhængige sygdomme

Country Status (26)

Country Link
US (1) US7378406B2 (da)
EP (1) EP1328276B1 (da)
JP (2) JP2004511522A (da)
KR (1) KR100632908B1 (da)
CN (1) CN1512886A (da)
AT (1) ATE310522T1 (da)
AU (2) AU2002218243B2 (da)
BG (1) BG107743A (da)
BR (1) BR0114665A (da)
CA (1) CA2423017C (da)
CY (1) CY1104981T1 (da)
CZ (1) CZ299942B6 (da)
DE (1) DE60115274T2 (da)
DK (1) DK1328276T3 (da)
EE (1) EE05259B1 (da)
ES (1) ES2253443T3 (da)
HR (1) HRP20030387A2 (da)
HU (1) HUP0301460A3 (da)
IL (2) IL154975A0 (da)
MX (1) MXPA03002954A (da)
NO (1) NO20031740L (da)
NZ (1) NZ538346A (da)
PL (1) PL360151A1 (da)
SI (1) SI1328276T1 (da)
SK (1) SK287124B6 (da)
WO (1) WO2002032430A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
DE10159217A1 (de) 2001-11-27 2003-06-05 Schering Ag 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
US9517240B2 (en) * 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
US20080261929A1 (en) * 2007-04-23 2008-10-23 Jens Hoffmann Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases
US20080268041A1 (en) * 2007-04-23 2008-10-30 Jens Hoffmann Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
EP2136796A2 (en) * 2007-04-23 2009-12-30 Bayer Schering Pharma Aktiengesellschaft Progesterone-receptor antagonist for use in brca-mediated cancer alone or as combination with antiestrogen
TWI477276B (zh) * 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
TWI539953B (zh) * 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007719A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
JP5894143B2 (ja) * 2010-03-22 2016-03-23 リプロス セラピューティクス インコーポレイテッド 抗黄体ホルモンの無毒送達のための組成物および方法
NZ702467A (en) 2012-05-31 2016-07-29 Repros Therapeutics Inc Formulations and methods for vaginal delivery of antiprogestins
CA2888377C (en) 2012-11-02 2021-02-02 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

Also Published As

Publication number Publication date
SK287124B6 (sk) 2009-12-07
DE60115274T2 (de) 2006-07-27
KR20030044007A (ko) 2003-06-02
ES2253443T3 (es) 2006-06-01
EP1328276A1 (en) 2003-07-23
IL154975A (en) 2007-05-15
IL154975A0 (en) 2003-10-31
HRP20030387A2 (en) 2005-04-30
EE200300155A (et) 2003-08-15
JP2010077158A (ja) 2010-04-08
HUP0301460A2 (hu) 2003-10-28
CA2423017A1 (en) 2002-04-25
KR100632908B1 (ko) 2006-10-13
NO20031740L (no) 2003-06-17
HUP0301460A3 (en) 2010-01-28
ATE310522T1 (de) 2005-12-15
PL360151A1 (en) 2004-09-06
CZ299942B6 (cs) 2008-12-29
US20040048841A1 (en) 2004-03-11
NO20031740D0 (no) 2003-04-15
EE05259B1 (et) 2010-02-15
CA2423017C (en) 2009-01-06
WO2002032430A1 (en) 2002-04-25
AU1824302A (en) 2002-04-29
US7378406B2 (en) 2008-05-27
AU2002218243B2 (en) 2006-07-13
NZ538346A (en) 2007-03-30
EP1328276B1 (en) 2005-11-23
BG107743A (bg) 2004-01-30
JP2004511522A (ja) 2004-04-15
SK4742003A3 (en) 2004-09-08
DE60115274D1 (de) 2005-12-29
MXPA03002954A (es) 2003-08-07
BR0114665A (pt) 2004-01-13
CY1104981T1 (el) 2010-03-03
CN1512886A (zh) 2004-07-14
SI1328276T1 (sl) 2006-04-30

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