JP2004510772A5 - - Google Patents

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Publication number
JP2004510772A5
JP2004510772A5 JP2002532439A JP2002532439A JP2004510772A5 JP 2004510772 A5 JP2004510772 A5 JP 2004510772A5 JP 2002532439 A JP2002532439 A JP 2002532439A JP 2002532439 A JP2002532439 A JP 2002532439A JP 2004510772 A5 JP2004510772 A5 JP 2004510772A5
Authority
JP
Japan
Prior art keywords
groups
pyrrolo
thienyl
formula
hydrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002532439A
Other languages
English (en)
Japanese (ja)
Other versions
JP4927306B2 (ja
JP2004510772A (ja
Filing date
Publication date
Priority claimed from EP00810886A external-priority patent/EP1193267A1/en
Application filed filed Critical
Publication of JP2004510772A publication Critical patent/JP2004510772A/ja
Publication of JP2004510772A5 publication Critical patent/JP2004510772A5/ja
Application granted granted Critical
Publication of JP4927306B2 publication Critical patent/JP4927306B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002532439A 2000-09-27 2001-09-27 タンパク質Ｊｕｎ−キナーゼのインヒビターとしての医薬的活性親水性スルホンアミド誘導体 Expired - Fee Related JP4927306B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00810886.2 2000-09-27
EP00810886A EP1193267A1 (en) 2000-09-27 2000-09-27 Pharmaceutically active hydrophilic sulfonamide derivatives as inhibitors of protein JunKinases
PCT/IB2001/001771 WO2002028856A1 (en) 2000-09-27 2001-09-27 Pharmaceutically active hydrophilic sulfonamide derivatives as inhibitors of protein junkinases

Publications (3)

Publication Number Publication Date
JP2004510772A JP2004510772A (ja) 2004-04-08
JP2004510772A5 true JP2004510772A5 (enExample) 2012-01-19
JP4927306B2 JP4927306B2 (ja) 2012-05-09

Family

ID=8174936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002532439A Expired - Fee Related JP4927306B2 (ja) 2000-09-27 2001-09-27 タンパク質Ｊｕｎ−キナーゼのインヒビターとしての医薬的活性親水性スルホンアミド誘導体

Country Status (8)

Country Link
US (1) US20040077632A1 (enExample)
EP (2) EP1193267A1 (enExample)
JP (1) JP4927306B2 (enExample)
AU (2) AU8799001A (enExample)
CA (1) CA2421417A1 (enExample)
ES (1) ES2392039T3 (enExample)
IL (1) IL154966A0 (enExample)
WO (1) WO2002028856A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1193256A1 (en) 2000-09-27 2002-04-03 Applied Research Systems ARS Holding N.V. Pharmaceutically active benzsulfonamide derivatives as inhibitors of JNK proteins
EP1193268A1 (en) * 2000-09-27 2002-04-03 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein Junkinases
WO2003010164A1 (en) * 2001-07-23 2003-02-06 Applied Research Systems Ars Holding N.V. Arylsulfonamide derivatives as c-jun-n-terminal kinases (jnk's) inhibitors
ES2385219T3 (es) 2003-09-12 2012-07-19 Merck Serono Sa Derivados de sulfonamida para el tratamiento de diabetes
JP5080241B2 (ja) * 2004-04-08 2012-11-21 メルク セローノ ソシエテ アノニム Ｊｎｋ阻害剤およびスクロスポリンを含んでなる組成物
BRPI0613042A2 (pt) 2005-07-15 2010-12-14 Serono Lab inibidores de jnk para o tratamento de endometriose
KR20080044836A (ko) 2005-07-15 2008-05-21 라보라뚜와르 세로노 에스. 에이. 자궁내막증 치료용 ｊｎｋ 억제제
EP2026802A2 (en) * 2006-06-02 2009-02-25 Laboratoires Serono SA Jnk inhibitors for treatment of skin diseases
US20100240720A1 (en) * 2009-03-20 2010-09-23 Burnham Institute For Medical Research Allosteric jnk inhibitors
US8946197B2 (en) 2009-11-16 2015-02-03 Chdi Foundation, Inc. Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof
US8889716B2 (en) 2011-05-10 2014-11-18 Chdi Foundation, Inc. Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof
CN112663077B (zh) * 2021-01-11 2022-07-01 陕西师范大学 一种苯并磺内酰胺类化合物的电化学制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2553414B1 (fr) * 1983-10-18 1986-08-14 Choay Sa Nouveaux benzenesulfonamides n-cyclises, leur procede de preparation et leur utilisation comme substance active de compositions pharmaceutiques
AU639536B2 (en) 1990-03-15 1993-07-29 Pharmacia & Upjohn Company Therapeutically useful heterocyclic indole compounds
US5106983A (en) 1990-04-30 1992-04-21 The United States Of America As Represented By The Secretary Of The Army Process of making carfentanil and related analgesics
US5238950A (en) * 1991-12-17 1993-08-24 Schering Corporation Inhibitors of platelet-derived growth factor
US5576313A (en) 1994-08-29 1996-11-19 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5744320A (en) * 1995-06-07 1998-04-28 Promega Corporation Quenching reagents and assays for enzyme-mediated luminescence
EP1001764A4 (en) * 1997-05-29 2005-08-24 Merck & Co Inc HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION
DE19743435A1 (de) * 1997-10-01 1999-04-08 Merck Patent Gmbh Benzamidinderivate
AR019322A1 (es) * 1998-06-18 2002-02-13 Smithkline Beecham Corp Derivados de sulfonilo sustituido por heterociclo-etanodionanilina sustituida por heterociclo, composicion farmaceutica que los contiene y su uso para lamanufactura de un medicamento
CZ302691B6 (cs) * 1998-07-08 2011-09-07 Sanofi - Aventis Deutschland GmbH N-Arylamidová sloucenina, zpusob její prípravy, farmaceutický prostredek tuto slouceninu obsahující, tato sloucenina pro použití jako aktivátor a pro použití k terapii nebo profylaxi
EP1088821A1 (en) * 1999-09-28 2001-04-04 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonamide derivatives
EP1193256A1 (en) * 2000-09-27 2002-04-03 Applied Research Systems ARS Holding N.V. Pharmaceutically active benzsulfonamide derivatives as inhibitors of JNK proteins
EP1193268A1 (en) * 2000-09-27 2002-04-03 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein Junkinases

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