ES2392039T3 - Derivados de sulfonamida hidrófilos farmacéuticamente activos como inhibidores de proteínas JunCinasas - Google Patents
Derivados de sulfonamida hidrófilos farmacéuticamente activos como inhibidores de proteínas JunCinasas Download PDFInfo
- Publication number
- ES2392039T3 ES2392039T3 ES01967621T ES01967621T ES2392039T3 ES 2392039 T3 ES2392039 T3 ES 2392039T3 ES 01967621 T ES01967621 T ES 01967621T ES 01967621 T ES01967621 T ES 01967621T ES 2392039 T3 ES2392039 T3 ES 2392039T3
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- Prior art keywords
- sulfonyl
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- alkyl
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- methyl
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- Expired - Lifetime
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Classifications
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- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00810886A EP1193267A1 (en) | 2000-09-27 | 2000-09-27 | Pharmaceutically active hydrophilic sulfonamide derivatives as inhibitors of protein JunKinases |
| EP00810886 | 2000-09-27 | ||
| PCT/IB2001/001771 WO2002028856A1 (en) | 2000-09-27 | 2001-09-27 | Pharmaceutically active hydrophilic sulfonamide derivatives as inhibitors of protein junkinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2392039T3 true ES2392039T3 (es) | 2012-12-04 |
Family
ID=8174936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES01967621T Expired - Lifetime ES2392039T3 (es) | 2000-09-27 | 2001-09-27 | Derivados de sulfonamida hidrófilos farmacéuticamente activos como inhibidores de proteínas JunCinasas |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040077632A1 (enExample) |
| EP (2) | EP1193267A1 (enExample) |
| JP (1) | JP4927306B2 (enExample) |
| AU (2) | AU8799001A (enExample) |
| CA (1) | CA2421417A1 (enExample) |
| ES (1) | ES2392039T3 (enExample) |
| IL (1) | IL154966A0 (enExample) |
| WO (1) | WO2002028856A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1193268A1 (en) * | 2000-09-27 | 2002-04-03 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein Junkinases |
| EP1193256A1 (en) * | 2000-09-27 | 2002-04-03 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active benzsulfonamide derivatives as inhibitors of JNK proteins |
| ATE419247T1 (de) * | 2001-07-23 | 2009-01-15 | Serono Lab | Arylsulfonamidderivate als hemmer c-jun- terminaler kinasen (jnk) |
| WO2005025558A1 (en) * | 2003-09-12 | 2005-03-24 | Applied Reserach Systems Ars Holding N.V. | Sulfonamide derivatives for the treatment of diabetes |
| KR20060134198A (ko) * | 2004-04-08 | 2006-12-27 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | Ｊｎｋ 저해제 및 시클로스포린을 포함하는 조성물 |
| KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 ｊｎｋ 억제제 |
| BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
| WO2007141224A2 (en) * | 2006-06-02 | 2007-12-13 | Laboratoires Serono Sa | Jnk inhibitors for treatment of skin diseases |
| US20100240720A1 (en) * | 2009-03-20 | 2010-09-23 | Burnham Institute For Medical Research | Allosteric jnk inhibitors |
| US8946197B2 (en) | 2009-11-16 | 2015-02-03 | Chdi Foundation, Inc. | Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof |
| US8889716B2 (en) | 2011-05-10 | 2014-11-18 | Chdi Foundation, Inc. | Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof |
| CN112663077B (zh) * | 2021-01-11 | 2022-07-01 | 陕西师范大学 | 一种苯并磺内酰胺类化合物的电化学制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2553414B1 (fr) * | 1983-10-18 | 1986-08-14 | Choay Sa | Nouveaux benzenesulfonamides n-cyclises, leur procede de preparation et leur utilisation comme substance active de compositions pharmaceutiques |
| EP0594593A1 (en) | 1990-03-15 | 1994-05-04 | PHARMACIA & UPJOHN COMPANY | Therapeutically useful heterocyclic indole compounds |
| US5106983A (en) | 1990-04-30 | 1992-04-21 | The United States Of America As Represented By The Secretary Of The Army | Process of making carfentanil and related analgesics |
| US5238950A (en) * | 1991-12-17 | 1993-08-24 | Schering Corporation | Inhibitors of platelet-derived growth factor |
| US5576313A (en) | 1994-08-29 | 1996-11-19 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US5744320A (en) * | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
| EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION |
| DE19743435A1 (de) * | 1997-10-01 | 1999-04-08 | Merck Patent Gmbh | Benzamidinderivate |
| AR019322A1 (es) * | 1998-06-18 | 2002-02-13 | Smithkline Beecham Corp | Derivados de sulfonilo sustituido por heterociclo-etanodionanilina sustituida por heterociclo, composicion farmaceutica que los contiene y su uso para lamanufactura de un medicamento |
| CZ302691B6 (cs) * | 1998-07-08 | 2011-09-07 | Sanofi - Aventis Deutschland GmbH | N-Arylamidová sloucenina, zpusob její prípravy, farmaceutický prostredek tuto slouceninu obsahující, tato sloucenina pro použití jako aktivátor a pro použití k terapii nebo profylaxi |
| EP1088821A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives |
| EP1193256A1 (en) * | 2000-09-27 | 2002-04-03 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active benzsulfonamide derivatives as inhibitors of JNK proteins |
| EP1193268A1 (en) * | 2000-09-27 | 2002-04-03 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein Junkinases |
-
2000
- 2000-09-27 EP EP00810886A patent/EP1193267A1/en not_active Withdrawn
-
2001
- 2001-09-27 JP JP2002532439A patent/JP4927306B2/ja not_active Expired - Fee Related
- 2001-09-27 IL IL15496601A patent/IL154966A0/xx unknown
- 2001-09-27 WO PCT/IB2001/001771 patent/WO2002028856A1/en not_active Ceased
- 2001-09-27 AU AU8799001A patent/AU8799001A/xx active Pending
- 2001-09-27 CA CA002421417A patent/CA2421417A1/en not_active Abandoned
- 2001-09-27 US US10/381,200 patent/US20040077632A1/en not_active Abandoned
- 2001-09-27 ES ES01967621T patent/ES2392039T3/es not_active Expired - Lifetime
- 2001-09-27 AU AU2001287990A patent/AU2001287990B2/en not_active Ceased
- 2001-09-27 EP EP01967621A patent/EP1322641B1/en not_active Expired - Lifetime
Also Published As
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|---|---|
| AU2001287990B2 (en) | 2006-04-13 |
| WO2002028856A1 (en) | 2002-04-11 |
| EP1322641B1 (en) | 2012-07-25 |
| JP4927306B2 (ja) | 2012-05-09 |
| AU8799001A (en) | 2002-04-15 |
| EP1193267A1 (en) | 2002-04-03 |
| JP2004510772A (ja) | 2004-04-08 |
| US20040077632A1 (en) | 2004-04-22 |
| CA2421417A1 (en) | 2002-04-11 |
| IL154966A0 (en) | 2003-10-31 |
| EP1322641A1 (en) | 2003-07-02 |
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