JP2004503233A - デング熱ウイルスエンベロープ糖タンパク質のプロ−アポトーシスフラグメント - Google Patents

デング熱ウイルスエンベロープ糖タンパク質のプロ−アポトーシスフラグメント Download PDF

Info

Publication number
JP2004503233A
JP2004503233A JP2002510516A JP2002510516A JP2004503233A JP 2004503233 A JP2004503233 A JP 2004503233A JP 2002510516 A JP2002510516 A JP 2002510516A JP 2002510516 A JP2002510516 A JP 2002510516A JP 2004503233 A JP2004503233 A JP 2004503233A
Authority
JP
Japan
Prior art keywords
polypeptide
polynucleotide
cell
den
egfp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002510516A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004503233A5 (cg-RX-API-DMAC7.html
Inventor
デスプレ,フィリップ
クラージョ,マリ−ピエール
ドベル,ヴァンサン
カトー,アデリーヌ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur filed Critical Institut Pasteur
Publication of JP2004503233A publication Critical patent/JP2004503233A/ja
Publication of JP2004503233A5 publication Critical patent/JP2004503233A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2002510516A 2000-06-16 2001-06-18 デング熱ウイルスエンベロープ糖タンパク質のプロ−アポトーシスフラグメント Pending JP2004503233A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21212900P 2000-06-16 2000-06-16
PCT/IB2001/001570 WO2001096376A2 (en) 2000-06-16 2001-06-18 Pro-apoptotic fragments of the dengue virus envelope glycoproteins

Publications (2)

Publication Number Publication Date
JP2004503233A true JP2004503233A (ja) 2004-02-05
JP2004503233A5 JP2004503233A5 (cg-RX-API-DMAC7.html) 2005-02-03

Family

ID=22789669

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002510516A Pending JP2004503233A (ja) 2000-06-16 2001-06-18 デング熱ウイルスエンベロープ糖タンパク質のプロ−アポトーシスフラグメント

Country Status (6)

Country Link
US (2) US6673895B2 (cg-RX-API-DMAC7.html)
EP (1) EP1311539A2 (cg-RX-API-DMAC7.html)
JP (1) JP2004503233A (cg-RX-API-DMAC7.html)
AU (1) AU2001282388A1 (cg-RX-API-DMAC7.html)
CA (1) CA2412257A1 (cg-RX-API-DMAC7.html)
WO (1) WO2001096376A2 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002211490A1 (en) * 2000-10-04 2002-04-15 The Trustees Of The University Of Pennsylvania Compositions and methods of using capsid protein from flaviviruses and pestiviruses
US7189403B2 (en) * 2003-06-30 2007-03-13 Institut Pasteur Attenuated flavivirus strains containing a mutated M-ectodomain and their applications
CA2508266A1 (fr) 2005-06-20 2006-12-20 Institut Pasteur Polypeptides chimeriques et leurs applications therapeutiques contre une infection a flaviviridae
DK1939214T3 (da) 2006-12-22 2013-10-14 Pasteur Institut Celler og metodik til at generere ikke-segmenterede negativstrengede RNA-vira

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136561A (en) * 1995-05-24 2000-10-24 Hawaii Biotechnology Group, Inc. Methods of preparing carboxy-terminally truncated recombinant flavivirus envelope glycoproteins employing drosophila melanogaster expression systems
CA2290090A1 (fr) * 1999-12-07 2001-06-07 Marie-Pierre Courageot Lignee cellulaire stable inductible n2aprm+e incluant l'adnc codant pour les glycoproteines prm et e du virus den-1: un systeme modele pour tester les proprietes inhibitrices des agents anti-viraux cibles pour les glycoproteines de l'enveloppe des flaviviridae

Also Published As

Publication number Publication date
AU2001282388A1 (en) 2001-12-24
WO2001096376A3 (en) 2003-03-13
WO2001096376A9 (en) 2003-10-23
CA2412257A1 (en) 2001-12-20
US20040049016A1 (en) 2004-03-11
EP1311539A2 (en) 2003-05-21
US6673895B2 (en) 2004-01-06
WO2001096376A2 (en) 2001-12-20
US20020086403A1 (en) 2002-07-04

Similar Documents

Publication Publication Date Title
Echeverri et al. Amino terminal regions of poliovirus 2C protein mediate membrane binding
DE3886363T2 (de) NANBV-Diagnostika und Vakzine.
US7326536B2 (en) Agents for treatment of HCV and methods of use
AU669843B2 (en) Repressors of the trans-activating function of papillomavirus E2 proteins
Satoh et al. Cleavage of hepatitis C virus nonstructural protein 5A by a caspase-like protease (s) in mammalian cells
DE60318954T2 (de) Inhibitor-resistente hcv-ns3-protease
DE69310734T2 (de) Peptid für die stimulierung von für hepatitis c virus spesifischen cytotoischen t lymphozyten
US7825085B2 (en) Fragments of NKp44 and NKp46 for targeting viral-infected and tumor cells
TWI450724B (zh) 新的融合蛋白質及其用於製備抗c型肝炎疫苗的用途
KR20180016410A (ko) 항바이러스 활성 효능을 가지는 펩티드 및 이를 포함하는 조성물
US20070184469A1 (en) Attenuated flavivirus strains containing a mutated m-ectodomain and their applications
Keil et al. Epitope mapping by deletion mutants and chimeras of two vesicular stomatitis virus glycoprotein genes expressed by a vaccinia virus vector
Syzdykova et al. Fluorescent tagging the NS1 protein in yellow fever virus: Replication-capable viruses which produce the secretory GFP-NS1 fusion protein
CA2070952A1 (en) Gene of hepatitis c virus or fragment thereof, polypeptide encoded by the same
US6673895B2 (en) Pro-apoptotic fragments of the dengue virus envelope glycoproteins
CA2221313A1 (en) Nucleotide and amino acid sequences of hypervariable region 1 of the envelope 2 gene of hepatitis c virus
Gething et al. Fusion activity of the hemagglutinin of influenza virus
FI117974B (fi) Parannettu rokote immunisointiin TBE-virusinfektioita vastaan ja menetelmä sen valmistamiseksi
US20030148265A1 (en) Anti-viral conjugate comprising a factor allowing the translocation of a protein across a cell membrane and comprising a single-chain antibody fragment directed against a viral protein
KR100209095B1 (ko) C형 간염 바이러스의 프로테아제의 활성을 측정할 수 있는 c형 간염 대체 바이러스, 그 재조합 유전자 및 그 용도
Mohan et al. Mutations selected in rotavirus enterotoxin NSP4 depend on the context of its expression
US20040101862A1 (en) Pro-apoptoic fragments of the dengue virus envelope glycoproteins
EP1976866A2 (en) Fusion protein comprising a hiv nef double mutant and its use therapy
KR101588332B1 (ko) 초파리 발현 시스템에서 황열바이러스 유사 입자 생산 방법
CN111778279B (zh) 一种HTLV-1 Env介导的细胞-细胞融合模型、制备方法及应用