JP2004502130A5 - - Google Patents
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- Publication number
- JP2004502130A5 JP2004502130A5 JP2001547549A JP2001547549A JP2004502130A5 JP 2004502130 A5 JP2004502130 A5 JP 2004502130A5 JP 2001547549 A JP2001547549 A JP 2001547549A JP 2001547549 A JP2001547549 A JP 2001547549A JP 2004502130 A5 JP2004502130 A5 JP 2004502130A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/458,171 US6376180B1 (en) | 1999-12-09 | 1999-12-09 | Methods of identifying compounds that bind to target species under isothermal denaturing conditions |
| PCT/US2000/042677 WO2001046693A2 (en) | 1999-12-09 | 2000-12-07 | Screening under isothermal denaturing conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004502130A JP2004502130A (ja) | 2004-01-22 |
| JP2004502130A5 true JP2004502130A5 (enExample) | 2005-12-22 |
Family
ID=23819666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001547549A Pending JP2004502130A (ja) | 1999-12-09 | 2000-12-07 | 等温変性下で標的種に結合する化合物の同定方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6376180B1 (enExample) |
| EP (1) | EP1364213A2 (enExample) |
| JP (1) | JP2004502130A (enExample) |
| AU (1) | AU775000B2 (enExample) |
| CA (1) | CA2392777A1 (enExample) |
| TW (1) | TWI240073B (enExample) |
| WO (1) | WO2001046693A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2203832A1 (en) * | 1995-09-08 | 1997-03-13 | Jaime E. Arenas | Screen for compounds with affinity for rna |
| WO1999024050A1 (en) | 1997-11-12 | 1999-05-20 | 3-Dimensional Pharmaceuticals, Inc. | High throughput method for functionally classifying proteins identified using a genomics approach |
| US6569631B1 (en) * | 1998-11-12 | 2003-05-27 | 3-Dimensional Pharmaceuticals, Inc. | Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes |
| US6582907B1 (en) * | 1999-12-09 | 2003-06-24 | Pharmacia & Upjohn Company | Use of fluorescence correlation spectroscopy to identify compounds that bind to target species under isothermal denaturing conditions |
| EP1274983B1 (en) * | 2000-03-21 | 2012-02-01 | The Board Of Trustees Of The University Of Illinois | Colorimetric artificial nose having an array of dyes and method for artificial olfaction |
| WO2002103321A2 (en) * | 2001-06-14 | 2002-12-27 | Anadys Pharmaceuticals, Inc. | Methods of screening for ligands of target molecules |
| US7672786B2 (en) * | 2003-07-02 | 2010-03-02 | Sergey Krylov | Non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM)—based methods for drug and diagnostic development |
| JP2006010491A (ja) * | 2004-06-25 | 2006-01-12 | Mitsubishi Kagaku Bio-Clinical Laboratories Inc | 体液分析方法及び分注良否判定装置 |
| GB201106548D0 (en) * | 2011-04-18 | 2011-06-01 | Evitraproteoma Ab | A method for determining ligand binding to a target protein using a thermal shift assahy |
| US9523693B2 (en) | 2011-04-18 | 2016-12-20 | Biotarget Engagement Interest Group Ab | Methods for determining ligand binding to a target protein using a thermal shift assay |
| EP3183580B1 (en) * | 2014-08-21 | 2025-03-26 | Eurofins DiscoverX Corporation | Homogenous thermal shift ligand binding assay |
| EP4455668A3 (en) | 2015-02-05 | 2025-02-19 | Promega Corporation | Luciferase-based thermal shift assays |
| CN109444209A (zh) * | 2018-10-26 | 2019-03-08 | 北京食品科学研究院 | 一种测量蛋清粉玻璃化转变温度的方法 |
| CN110095421B (zh) * | 2019-05-17 | 2022-02-08 | 淮海工学院 | 一种胶原蛋白变性温度的测定方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3939350A (en) * | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US5585277A (en) | 1993-06-21 | 1996-12-17 | Scriptgen Pharmaceuticals, Inc. | Screening method for identifying ligands for target proteins |
| US5679582A (en) | 1993-06-21 | 1997-10-21 | Scriptgen Pharmaceuticals, Inc. | Screening method for identifying ligands for target proteins |
| CA2184195C (en) * | 1995-10-25 | 2002-04-16 | Andrew Pakula | Screening method for identifying ligands for target proteins |
| WO1997020952A1 (en) * | 1995-12-07 | 1997-06-12 | Scriptgen Pharmaceuticals, Inc. | A fluorescence-based screening method for identifying ligands |
| US6036920A (en) | 1996-05-09 | 2000-03-14 | 3-Dimensional Pharmaceuticals, Inc. | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization |
| EP0836090A1 (en) | 1996-10-12 | 1998-04-15 | Evotec BioSystems GmbH | Method of analysis of samples by determination of the distribution of specific brightnesses of particles |
| PT1036192E (pt) * | 1997-12-05 | 2003-06-30 | Upjohn Co | Ensaios de pesquisa de alto rendimento a base de fluorescencia para proteina-quinases e -fosfatases |
| US6242190B1 (en) * | 1999-12-01 | 2001-06-05 | John Hopkins University | Method for high throughput thermodynamic screening of ligands |
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1999
- 1999-12-09 US US09/458,171 patent/US6376180B1/en not_active Expired - Fee Related
-
2000
- 2000-12-04 TW TW089125804A patent/TWI240073B/zh not_active IP Right Cessation
- 2000-12-07 CA CA002392777A patent/CA2392777A1/en not_active Abandoned
- 2000-12-07 EP EP00992870A patent/EP1364213A2/en not_active Withdrawn
- 2000-12-07 AU AU47137/01A patent/AU775000B2/en not_active Ceased
- 2000-12-07 JP JP2001547549A patent/JP2004502130A/ja active Pending
- 2000-12-07 WO PCT/US2000/042677 patent/WO2001046693A2/en not_active Ceased
-
2001
- 2001-11-13 US US10/008,090 patent/US6713260B2/en not_active Expired - Fee Related