JP2003532420A - アデニンヌクレオチドトランスロケーター（ａｎｔ）の産生、新規ａｎｔリガンドおよびそのスクリーニングアッセイ - Google Patents

アデニンヌクレオチドトランスロケーター（ａｎｔ）の産生、新規ａｎｔリガンドおよびそのスクリーニングアッセイ

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Publication number
JP2003532420A
JP2003532420A JP2001582533A JP2001582533A JP2003532420A JP 2003532420 A JP2003532420 A JP 2003532420A JP 2001582533 A JP2001582533 A JP 2001582533A JP 2001582533 A JP2001582533 A JP 2001582533A JP 2003532420 A JP2003532420 A JP 2003532420A
Authority
JP
Japan
Prior art keywords
ant
polypeptide
adenine nucleotide
nucleotide translocator
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001582533A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003532420A5 (https=
Inventor
クリステン エム． アンダーソン，
ロバート イー． デイビス，
ウィリアム クレベンガー，
サンドラ エイリーン ウィリー，
スコット ダブリュー． ミラー，
トマス アール． スザボ，
ソウミトラ エス． ゴシュ，
ウォルター エイチ． ムース，
ヤチョン ペイ，
エイミー ケイ． キャロル，
Original Assignee
マイトコー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マイトコー filed Critical マイトコー
Publication of JP2003532420A publication Critical patent/JP2003532420A/ja
Publication of JP2003532420A5 publication Critical patent/JP2003532420A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2001582533A 2000-05-11 2001-05-11 アデニンヌクレオチドトランスロケーター（ａｎｔ）の産生、新規ａｎｔリガンドおよびそのスクリーニングアッセイ Pending JP2003532420A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56932700A 2000-05-11 2000-05-11
US09/569,327 2000-05-11
PCT/US2001/015416 WO2001085944A2 (en) 2000-05-11 2001-05-11 Production of adenine nucleotide translocator (ant), novel ant ligands and screening assays therefor

Publications (2)

Publication Number Publication Date
JP2003532420A true JP2003532420A (ja) 2003-11-05
JP2003532420A5 JP2003532420A5 (https=) 2007-03-08

Family

ID=24274963

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001582533A Pending JP2003532420A (ja) 2000-05-11 2001-05-11 アデニンヌクレオチドトランスロケーター（ａｎｔ）の産生、新規ａｎｔリガンドおよびそのスクリーニングアッセイ

Country Status (5)

Country Link
EP (2) EP1783221A1 (https=)
JP (1) JP2003532420A (https=)
AU (1) AU2001261518A1 (https=)
CA (1) CA2407886A1 (https=)
WO (1) WO2001085944A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011521941A (ja) * 2008-05-30 2011-07-28 ミトロジクス Ａｎｔ−リガンド分子および生物学的アプリケ−ション

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0328048D0 (en) * 2003-12-04 2004-01-07 Univ Sheffield Gene screen
EP2314600B1 (en) * 2008-07-15 2017-07-12 Dalian Zhen-Ao Pharmaceutical Co., Ltd. Myocardial peptide, preparation method and uses thereof
CN104678031B (zh) * 2015-01-23 2016-05-04 四川省中医药科学院 高效液相色谱法检测苍术苷和/或羧基苍术苷的方法
CN116593431B (zh) * 2023-04-09 2025-11-07 湖南科技大学三亚研究院 一种基于亲和传感器法的米酵菌酸毒素便携式检测装置及检测方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE60803T1 (de) * 1983-06-27 1991-02-15 Genentech Inc Uebertragbare induzierbare kontrollsysteme, diese enthaltende expressionsvektoren, mit diesen transformierte mikroorganismen und ihre verwendung bei der expression von exogenem protein.
DE69122016T2 (de) * 1990-09-26 1997-04-30 Sumitomo Chemical Co Mitochondriales P450
US5656495A (en) * 1995-01-20 1997-08-12 Bristol-Myers Squibb Company Expression vector for human topoisomerase I
US5859215A (en) * 1995-10-25 1999-01-12 Wallac Oy Biospecific binding reactants labelled with luminescent lanthanide chelates and their use
US6013858A (en) * 1996-11-01 2000-01-11 Emory University Mouse lacking heart-muscle adenine nucleotide translocator protein and methods
DE19653498C1 (de) * 1996-12-20 1998-07-23 Wolf M Prof Dr Bertling Klonierungsvektor-System mit Fusionssequenz
US20030044776A1 (en) * 1998-09-25 2003-03-06 James A. Dykens Compositions and methods for identifying agents that alter mitochondrial permeability transition pores
CA2349444A1 (en) * 1998-11-03 2000-05-11 Mitokor Production of adenine nucleotide translocator (ant), novel ant ligands and screening assays therefor
WO2001002598A2 (en) * 1999-06-30 2001-01-11 Knoll Gmbh Screening for compounds modulating mitochondrial proton leak
US6562563B1 (en) * 1999-11-03 2003-05-13 Mitokor Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN5002031175, ＣＯＺＥＮＳ， Ａ．Ｌ．, ＪＯＵＲＮＡＬ ＯＦ ＭＯＬＥＣＵＬＡＲ ＢＩＯＬＯＧＹ, 19890305, Ｖ２０６, Ｐ２６１−２８０ *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011521941A (ja) * 2008-05-30 2011-07-28 ミトロジクス Ａｎｔ−リガンド分子および生物学的アプリケ−ション

Also Published As

Publication number Publication date
WO2001085944A2 (en) 2001-11-15
AU2001261518A1 (en) 2001-11-20
WO2001085944A3 (en) 2002-08-29
EP1283884A2 (en) 2003-02-19
EP1783221A1 (en) 2007-05-09
CA2407886A1 (en) 2001-11-15

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