JP2003530870A5 - - Google Patents
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- Publication number
- JP2003530870A5 JP2003530870A5 JP2001578463A JP2001578463A JP2003530870A5 JP 2003530870 A5 JP2003530870 A5 JP 2003530870A5 JP 2001578463 A JP2001578463 A JP 2001578463A JP 2001578463 A JP2001578463 A JP 2001578463A JP 2003530870 A5 JP2003530870 A5 JP 2003530870A5
- Authority
- JP
- Japan
- Prior art keywords
- material composition
- domain
- formula
- apo
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000463 material Substances 0.000 description 10
- 102000005666 Apolipoprotein A-I Human genes 0.000 description 3
- 108010059886 Apolipoprotein A-I Proteins 0.000 description 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- LVXACIPXSUHNDE-CTNRBZHLSA-N 98805-74-4 Chemical compound C([C@@H](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C(C)C)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(O)C=C1 LVXACIPXSUHNDE-CTNRBZHLSA-N 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19892000P | 2000-04-21 | 2000-04-21 | |
| US60/198,920 | 2000-04-21 | ||
| PCT/US2001/013068 WO2001081376A2 (en) | 2000-04-21 | 2001-04-23 | Apo-ai/aii peptide derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003530870A JP2003530870A (ja) | 2003-10-21 |
| JP2003530870A5 true JP2003530870A5 (cg-RX-API-DMAC10.html) | 2006-01-05 |
Family
ID=22735445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001578463A Withdrawn JP2003530870A (ja) | 2000-04-21 | 2001-04-23 | Ａｐｏ−ＡＩ／ＡＩＩペプチド誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6743778B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP1290013B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2003530870A (cg-RX-API-DMAC10.html) |
| AT (1) | ATE319737T1 (cg-RX-API-DMAC10.html) |
| AU (2) | AU2001257173B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2407083A1 (cg-RX-API-DMAC10.html) |
| DE (1) | DE60117781T2 (cg-RX-API-DMAC10.html) |
| DK (1) | DK1290013T3 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2260219T3 (cg-RX-API-DMAC10.html) |
| MX (1) | MXPA02010324A (cg-RX-API-DMAC10.html) |
| PT (1) | PT1290013E (cg-RX-API-DMAC10.html) |
| WO (1) | WO2001081376A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003530871A (ja) * | 2000-04-21 | 2003-10-21 | アムジエン・インコーポレーテツド | インテグリン／接着因子アンタゴニスト |
| US8116889B2 (en) * | 2002-06-27 | 2012-02-14 | Openpeak Inc. | Method, system, and computer program product for managing controlled residential or non-residential environments |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| US7329725B1 (en) * | 2003-10-29 | 2008-02-12 | Nastech Pharmaceutical Company Inc. | Phage displayed Trp cage ligands |
| BRPI0406605B8 (pt) | 2003-11-13 | 2021-05-25 | Hanmi Holdings Co Ltd | conjugado de proteína, método para a preparação do mesmo e composição farmacêutica para intensificar a duração e estabilidade in vivo de um polipeptídeo fisiologicamente ativo |
| US8110665B2 (en) | 2003-11-13 | 2012-02-07 | Hanmi Holdings Co., Ltd. | Pharmaceutical composition comprising an immunoglobulin FC region as a carrier |
| KR20070089996A (ko) * | 2004-12-06 | 2007-09-04 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 세동맥의 구조 및 기능의 개선 방법 |
| US7704953B2 (en) * | 2006-02-17 | 2010-04-27 | Mdrna, Inc. | Phage displayed cell binding peptides |
| WO2007103775A2 (en) * | 2006-03-03 | 2007-09-13 | Washington University In St. Louis | Biomaterials having nanoscale layers and coatings |
| ES2402823T3 (es) * | 2006-06-01 | 2013-05-09 | Institut De Cardiologie De Montreal | Compuesto para uso en el tratamiento de estenosis valvular |
| MX2011008599A (es) * | 2009-02-16 | 2011-11-18 | Cerenis Therapeutics Sa | Peptidos mimeticos de la apolipoproteina a-i. |
| AU2014268255B2 (en) * | 2009-02-16 | 2016-04-21 | Cerenis Therapeutics Holding Sa | Apolipoprotein a-i mimics |
| RU2016144908A (ru) | 2014-05-02 | 2018-06-05 | Серени Терапеутикс Холдинг Са | Маркеры hdl-терапии |
| AU2016238290B9 (en) | 2015-03-25 | 2019-06-13 | The Regents Of The University Of Michigan | Compositions and methods for delivery of biomacromolecule agents |
| EP3490579B1 (en) | 2016-07-27 | 2025-09-10 | Hartis-Pharma SA | Therapeutic combinations to treat red blood cell disorders |
| KR20260012291A (ko) | 2018-07-12 | 2026-01-26 | 더 리젠츠 오브 더 유니버시티 오브 미시간 | 면역 반응을 조절할 수 있는 금속 함유 제형의 조성물 및 방법 |
| KR20230004605A (ko) | 2020-04-16 | 2023-01-06 | 아비오닉스 파마 에스에이 | 지질 결합 단백질-기반 복합체를 사용하여 급성 상태를 치료하는 방법 |
| CA3197168A1 (en) | 2020-10-01 | 2022-04-07 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| CA3216226A1 (en) | 2021-04-15 | 2022-10-20 | Abionyx Pharma Sa | Use of lipid binding protein-based complexes in organ preservation solutions |
| CN119317440A (zh) | 2022-04-06 | 2025-01-14 | 阿比奥尼克斯制药公司 | 使用基于脂质结合蛋白的复合物治疗白细胞增多、内皮功能障碍和心脏炎的方法 |
| US20250230208A1 (en) | 2022-04-06 | 2025-07-17 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| CA3258787A1 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | METHODS OF TREATMENT OF HYPERINFLAMMATORY DISEASES USING LIPID-BINDING PROTEIN COMPLEXES |
| WO2023237935A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein-based complexes |
| KR20260010675A (ko) | 2023-01-13 | 2026-01-21 | 아비오닉스 파마 에스에이 | 지질 결합 단백질 분자 치료 |
| IL327995A (en) | 2023-10-31 | 2026-06-01 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1023287A (en) | 1972-12-08 | 1977-12-27 | Boehringer Mannheim G.M.B.H. | Process for the preparation of carrier-bound proteins |
| US3941763A (en) | 1975-03-28 | 1976-03-02 | American Home Products Corporation | PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates |
| US4195128A (en) | 1976-05-03 | 1980-03-25 | Bayer Aktiengesellschaft | Polymeric carrier bound ligands |
| US4330440A (en) | 1977-02-08 | 1982-05-18 | Development Finance Corporation Of New Zealand | Activated matrix and method of activation |
| CA1093991A (en) | 1977-02-17 | 1981-01-20 | Hideo Hirohara | Enzyme immobilization with pullulan gel |
| US4229537A (en) | 1978-02-09 | 1980-10-21 | New York University | Preparation of trichloro-s-triazine activated supports for coupling ligands |
| US4289872A (en) | 1979-04-06 | 1981-09-15 | Allied Corporation | Macromolecular highly branched homogeneous compound based on lysine units |
| US4925673A (en) | 1986-08-18 | 1990-05-15 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents encapsulated with proteinoids |
| US5229490A (en) | 1987-05-06 | 1993-07-20 | The Rockefeller University | Multiple antigen peptide system |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
| US5733731A (en) | 1991-10-16 | 1998-03-31 | Affymax Technologies N.V. | Peptide library and screening method |
| US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| SE9103701D0 (sv) * | 1991-12-13 | 1991-12-13 | Kabi Pharmacia Ab | Apolipoprotein |
| ATE156158T1 (de) | 1992-04-14 | 1997-08-15 | Cornell Res Foundation Inc | Makromoleküle auf basis von dendritischen polymeren und verfahren zur herstellung |
| US5792451A (en) | 1994-03-02 | 1998-08-11 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
| US5922545A (en) | 1993-10-29 | 1999-07-13 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| US5739277A (en) | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
| US6127977A (en) | 1996-11-08 | 2000-10-03 | Cohen; Nathan | Microstrip patch antenna with fractal structure |
| CA2249195A1 (en) * | 1996-03-18 | 1997-09-25 | Board Of Regents, The University Of Texas System | Immunoglobin-like domains with increased half lives |
| US6156727A (en) | 1996-09-05 | 2000-12-05 | Uab Research Foundation | Anti-atherosclerotic peptides and a transgenic mouse model of antherosclerosis |
| EP0934526B1 (en) | 1996-10-08 | 2003-01-08 | U-BISys B.V. | Methods and means for selecting peptides and proteins having specific affinity for a target |
| US6046166A (en) | 1997-09-29 | 2000-04-04 | Jean-Louis Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| GB9815505D0 (en) * | 1998-07-16 | 1998-09-16 | Adprotech Plc | Polypeptide derivatives |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
-
2001
- 2001-04-23 DK DK01930664T patent/DK1290013T3/da active
- 2001-04-23 CA CA002407083A patent/CA2407083A1/en not_active Abandoned
- 2001-04-23 WO PCT/US2001/013068 patent/WO2001081376A2/en not_active Ceased
- 2001-04-23 ES ES01930664T patent/ES2260219T3/es not_active Expired - Lifetime
- 2001-04-23 JP JP2001578463A patent/JP2003530870A/ja not_active Withdrawn
- 2001-04-23 AU AU2001257173A patent/AU2001257173B2/en not_active Ceased
- 2001-04-23 PT PT01930664T patent/PT1290013E/pt unknown
- 2001-04-23 AU AU5717301A patent/AU5717301A/xx active Pending
- 2001-04-23 EP EP01930664A patent/EP1290013B1/en not_active Expired - Lifetime
- 2001-04-23 AT AT01930664T patent/ATE319737T1/de not_active IP Right Cessation
- 2001-04-23 DE DE60117781T patent/DE60117781T2/de not_active Expired - Lifetime
- 2001-04-23 MX MXPA02010324A patent/MXPA02010324A/es unknown
- 2001-04-23 US US09/840,669 patent/US6743778B2/en not_active Expired - Fee Related
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