JP2003519164A5 - - Google Patents

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Publication number
JP2003519164A5
JP2003519164A5 JP2001549618A JP2001549618A JP2003519164A5 JP 2003519164 A5 JP2003519164 A5 JP 2003519164A5 JP 2001549618 A JP2001549618 A JP 2001549618A JP 2001549618 A JP2001549618 A JP 2001549618A JP 2003519164 A5 JP2003519164 A5 JP 2003519164A5
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JP
Japan
Prior art keywords
peptide
release
polymer
formulation
dth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001549618A
Other languages
English (en)
Japanese (ja)
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JP2003519164A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/000030 external-priority patent/WO2001049249A2/en
Publication of JP2003519164A publication Critical patent/JP2003519164A/ja
Publication of JP2003519164A5 publication Critical patent/JP2003519164A5/ja
Pending legal-status Critical Current

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JP2001549618A 1999-12-31 2001-01-02 ポリマーマトリクスに基づく生理活性化合物徐放調節用医薬製剤 Pending JP2003519164A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17413799P 1999-12-31 1999-12-31
US60/174,137 1999-12-31
PCT/US2001/000030 WO2001049249A2 (en) 1999-12-31 2001-01-02 Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix

Publications (2)

Publication Number Publication Date
JP2003519164A JP2003519164A (ja) 2003-06-17
JP2003519164A5 true JP2003519164A5 (de) 2011-04-28

Family

ID=22634986

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001549618A Pending JP2003519164A (ja) 1999-12-31 2001-01-02 ポリマーマトリクスに基づく生理活性化合物徐放調節用医薬製剤

Country Status (5)

Country Link
EP (1) EP1263453A4 (de)
JP (1) JP2003519164A (de)
AU (1) AU784226B2 (de)
CA (1) CA2396037A1 (de)
WO (1) WO2001049249A2 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7326425B2 (en) 1999-12-31 2008-02-05 Rutgers, The State University Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CA2544678C (en) 2003-11-05 2013-12-31 Sunesis Pharmaceuticals, Inc. Modulators of cellular adhesion
SI2444079T1 (sl) 2005-05-17 2017-05-31 Sarcode Bioscience Inc. Sestavki in postopki za zdravljenje očesnih motenj
MX2008010126A (es) 2006-02-08 2010-02-22 Tyrx Pharma Inc Protesis de malla temporalmente rigidizadas.
US8315700B2 (en) 2006-02-08 2012-11-20 Tyrx, Inc. Preventing biofilm formation on implantable medical devices
US9265865B2 (en) 2006-06-30 2016-02-23 Boston Scientific Scimed, Inc. Stent having time-release indicator
US9023114B2 (en) 2006-11-06 2015-05-05 Tyrx, Inc. Resorbable pouches for implantable medical devices
WO2008127411A1 (en) 2006-11-06 2008-10-23 Tyrx Pharma, Inc. Mesh pouches for implantable medical devices
CA2682190C (en) 2007-03-29 2015-01-27 Tyrx Pharma, Inc. Biodegradable, polymer coverings for breast implants
EP2150119B1 (de) 2007-05-02 2018-04-11 Tyrx, Inc. Dihydroxybenzoatpolymere und ihre verwendung
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2209371B1 (de) 2007-10-19 2017-01-04 SARcode Bioscience Inc. Zusammensetzungen und verfahren zur behandlung von diabetischer retinopathie
US8080562B2 (en) 2008-04-15 2011-12-20 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
WO2010006046A1 (en) 2008-07-10 2010-01-14 Tyrx Pharma, Inc. Nsaid delivery from polyarylates
EP2321341B1 (de) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
CA2833960C (en) 2008-09-22 2015-12-22 Tyrx, Inc. Linear polyesteramides from aminophenolic esters
US9839628B2 (en) 2009-06-01 2017-12-12 Tyrx, Inc. Compositions and methods for preventing sternal wound infections
EP2437724B1 (de) * 2009-06-01 2015-09-30 Tyrx, Inc. Zusammensetzungen und verfahren zur verhinderung von wundinfektionen im brustbein
EP2459638B1 (de) * 2009-07-31 2017-09-27 Rutgers, The State University of New Jersey Monomere und daraus hergestellte phasengetrennte biokompatible polymerzusammensetzungen zur verwendung in der medizin
US8409279B2 (en) 2009-10-01 2013-04-02 Lipose Corporation Breast implant implantation method and apparatus
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
EP3489313A1 (de) 2010-08-25 2019-05-29 Tyrx, Inc. Neuartige beschichtungen für medizinische vorrichtung
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AU2011326417A1 (en) 2010-11-12 2013-05-09 Tyrx, Inc. Anchorage devices comprising an active pharmaceutical ingredient
AU2012283875B2 (en) 2011-07-20 2016-05-12 Medtronic, Inc. Drug eluting mesh to prevent infection of indwelling transdermal devices
US9085553B2 (en) 2012-07-25 2015-07-21 SARcode Bioscience, Inc. LFA-1 inhibitor and methods of preparation and polymorph thereof
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
WO2014137454A1 (en) 2013-03-07 2014-09-12 Tyrx, Inc. Methods and compositions to inhibit the assemblage of microbial cells irreversibly associated with surfaces of medical devices
EP2970384A1 (de) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonisten der guanylatcyclase und deren verwendungen
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
US20160220630A1 (en) 2013-10-10 2016-08-04 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
EP3065788A1 (de) 2013-11-08 2016-09-14 Tyrx, Inc. Antimikrobielle zusammensetzungen und verfahren zur verhütung von infektionen in chirurgischen einstichstellen
WO2016020308A1 (en) * 2014-08-04 2016-02-11 Janssen Sciences Ireland Uc Compacted solid dosage form
EP3402804A1 (de) 2016-01-11 2018-11-21 Synergy Pharmaceuticals Inc. Formulierungen und verfahren zur behandlung von colitis ulcerosa

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US5587507A (en) * 1995-03-31 1996-12-24 Rutgers, The State University Synthesis of tyrosine derived diphenol monomers
US5658995A (en) * 1995-11-27 1997-08-19 Rutgers, The State University Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide)
US6120491A (en) * 1997-11-07 2000-09-19 The State University Rutgers Biodegradable, anionic polymers derived from the amino acid L-tyrosine
JP4410857B2 (ja) * 1997-02-18 2010-02-03 ラットガーズ ザ ステイト ユニヴァーシティ ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー
DE19719817A1 (de) * 1997-05-13 1998-11-19 Hoechst Ag Substituierte 6- und 7-Aminotetrahydroisochinolincarbonsäuren
US6267987B1 (en) * 1997-12-12 2001-07-31 Samyang Corporation Positively charged poly[alpha-(omega-aminoalkyl) glycolic acid] for the delivery of a bioactive agent via tissue and cellular uptake
US20020151668A1 (en) * 1998-04-13 2002-10-17 Ken James Construction of copolymer libraries
EP1157421A1 (de) * 1999-02-05 2001-11-28 Alien Technology Corporation Verfahren und vorrichtungen zum herstellen von baugruppen

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