JP2003511550A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003511550A5 JP2003511550A5 JP2001531088A JP2001531088A JP2003511550A5 JP 2003511550 A5 JP2003511550 A5 JP 2003511550A5 JP 2001531088 A JP2001531088 A JP 2001531088A JP 2001531088 A JP2001531088 A JP 2001531088A JP 2003511550 A5 JP2003511550 A5 JP 2003511550A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- polyanhydride
- iii
- formula
- hydroxy acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 description 6
- 229920002732 Polyanhydride Polymers 0.000 description 3
- 150000001280 alpha hydroxy acids Chemical class 0.000 description 2
- 210000003491 Skin Anatomy 0.000 description 1
- 125000002947 alkylene group Chemical group 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 125000004432 carbon atoms Chemical group C* 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/422,294 US6468519B1 (en) | 1997-09-10 | 1999-10-21 | Polyanhydrides with biologically active degradation products |
US09/422,294 | 1999-10-21 | ||
PCT/US2000/027962 WO2001028492A2 (en) | 1999-10-21 | 2000-10-11 | Polyanhydrides with biologically active degradation products |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2003511550A JP2003511550A (ja) | 2003-03-25 |
JP2003511550A5 true JP2003511550A5 (US07794700-20100914-C00152.png) | 2007-11-29 |
Family
ID=23674230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001531088A Pending JP2003511550A (ja) | 1999-10-21 | 2000-10-11 | 生物学的に活性な分解産物を有するポリ酸無水物 |
Country Status (9)
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6486214B1 (en) * | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
US7985415B2 (en) * | 1997-09-10 | 2011-07-26 | Rutgers, The State University Of New Jersey | Medical devices employing novel polymers |
US6468519B1 (en) * | 1997-09-10 | 2002-10-22 | Rutgers, The State University Of New Jersey | Polyanhydrides with biologically active degradation products |
US7122615B1 (en) | 1998-09-10 | 2006-10-17 | Rutgers, The State University Of New Jersey | Polyanhydrides with therapeutically useful degradation products |
EP2095817A1 (en) * | 1999-12-07 | 2009-09-02 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
US20040038948A1 (en) | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
US6527801B1 (en) | 2000-04-13 | 2003-03-04 | Advanced Cardiovascular Systems, Inc. | Biodegradable drug delivery material for stent |
CA2771263A1 (en) * | 2000-07-27 | 2002-02-07 | Rutgers, The State University | Therapeutic polyesters and polyamides |
US6602915B2 (en) | 2000-07-27 | 2003-08-05 | Rutgers, The State University Of New Jersey | Therapeutic azo-compounds for drug delivery |
MXPA04004701A (es) * | 2001-11-23 | 2005-07-01 | Univ Rutgers | Sintesis mejorada de polianhidridos. |
US20040096476A1 (en) * | 2002-07-17 | 2004-05-20 | Uhrich Kathryn E. | Therapeutic devices for patterned cell growth |
US6932930B2 (en) * | 2003-03-10 | 2005-08-23 | Synecor, Llc | Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same |
US9445901B2 (en) * | 2003-03-12 | 2016-09-20 | Deger C. Tunc | Prosthesis with sustained release analgesic |
EP1626748B1 (en) * | 2003-05-13 | 2012-07-11 | Medtronic, Inc. | Moisture curable materials for delivery of agents, methods, and medical devices |
US20050249697A1 (en) * | 2003-09-24 | 2005-11-10 | Uhrich Kathryn E | Compositions and methods for the inhibition of bone growth and resorption |
US8352712B2 (en) * | 2004-05-06 | 2013-01-08 | International Business Machines Corporation | Method and system for specualtively sending processor-issued store operations to a store queue with full signal asserted |
JP5247144B2 (ja) * | 2004-05-14 | 2013-07-24 | インターフェース バイオロジクス インコーポレーティッド | 高分子カップリング剤およびそれらから製造された薬学的に活性のあるポリマー |
CA2467321A1 (en) * | 2004-05-14 | 2005-11-14 | Paul J. Santerre | Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
US7858077B2 (en) * | 2005-01-28 | 2010-12-28 | Bezwada Biomedical Llc | Functionalized phenolic esters and amides and polymers therefrom |
US7691364B2 (en) * | 2005-01-28 | 2010-04-06 | Bezwada Biomedical, Llc | Functionalized drugs and polymers derived therefrom |
US20060193891A1 (en) * | 2005-02-25 | 2006-08-31 | Robert Richard | Medical devices and therapeutic delivery devices composed of bioabsorbable polymers produced at room temperature, method of making the devices, and a system for making the devices |
EP1898832A4 (en) * | 2005-05-23 | 2013-01-02 | Univ Rutgers | RAPIDLY DEGRADING POLYMERS |
WO2007053794A2 (en) * | 2005-10-21 | 2007-05-10 | Bezwada Biomedical Llc | Functionalized phenolic compounds and absorbable therefrom |
US8007526B2 (en) | 2005-12-01 | 2011-08-30 | Bezwada Biomedical, Llc | Difunctionalized aromatic compounds and polymers therefrom |
US7935843B2 (en) * | 2005-12-09 | 2011-05-03 | Bezwada Biomedical, Llc | Functionalized diphenolics and absorbable polymers therefrom |
US9603941B2 (en) * | 2006-01-24 | 2017-03-28 | Minghui Chai | Method of preparing dendritic drugs |
US20070225472A1 (en) * | 2006-03-23 | 2007-09-27 | Varshney Sunil K | Polyanhydride polymers and their uses in biomedical devices |
EP2032614A2 (en) * | 2006-06-06 | 2009-03-11 | Rutgers, The State University Of New Jersey | Iodinated polymers |
WO2008034019A2 (en) | 2006-09-13 | 2008-03-20 | Polymerix Corporation | Active agents and their oligomers and polymers |
EP2077861A2 (en) * | 2006-10-23 | 2009-07-15 | Bioabsorbable Therapeutics, Inc. | A drug-release composition having a therapeutic carrier |
EP2066294B9 (en) * | 2006-11-06 | 2013-04-10 | Whitehead Institute | Immunomodulating compositions and methods of use thereof |
US9457047B2 (en) | 2006-11-06 | 2016-10-04 | Whitehead Institute | Immunomodulating compositions and methods of use thereof |
US8747832B2 (en) * | 2007-04-12 | 2014-06-10 | Rutgers, The State University Of New Jersey | Biodegradable polyanhydrides with natural bioactive molecules |
US8217134B2 (en) | 2007-08-30 | 2012-07-10 | Bezwada Biomedical, Llc | Controlled release of biologically active compounds |
US8026285B2 (en) | 2007-09-04 | 2011-09-27 | Bezwada Biomedical, Llc | Control release of biologically active compounds from multi-armed oligomers |
US8048980B2 (en) | 2007-09-17 | 2011-11-01 | Bezwada Biomedical, Llc | Hydrolysable linkers and cross-linkers for absorbable polymers |
WO2010148104A2 (en) * | 2009-06-16 | 2010-12-23 | L'oreal S.A. | Topical compositions containing a polymer for releasing at least one salicylic acid compound |
WO2010148101A2 (en) * | 2009-06-16 | 2010-12-23 | L'oreal S.A. | Topical compositions containing a polymer for releasing at least one salicylic acid compound |
US8741317B2 (en) | 2010-08-19 | 2014-06-03 | Rutgers, The State University Of New Jersey | Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery |
US9144579B2 (en) | 2012-08-17 | 2015-09-29 | Rutgers, The State University Of New Jersey | Polyesters and methods of use thereof |
US20140120057A1 (en) | 2012-10-25 | 2014-05-01 | Rutgers, The State University Of New Jersey | Polymers and methods thereof for wound healing |
US9387250B2 (en) | 2013-03-15 | 2016-07-12 | Rutgers, The State University Of New Jersey | Therapeutic compositions for bone repair |
WO2014194055A1 (en) | 2013-05-29 | 2014-12-04 | Rutgers, The State University Of New Jersey | Antioxidant-based poly(anhydride-esters) |
WO2015191742A1 (en) | 2014-06-13 | 2015-12-17 | Rutgers, The State University Of New Jersey | Process and intermediates for preparing poly(anhydride-esters) |
WO2016164898A1 (en) | 2015-04-10 | 2016-10-13 | Rutgers, The State University Of New Jersey | Kojic acid polymers |
CA3087898A1 (en) | 2018-02-02 | 2019-08-08 | Ripple Therapeutics Corporation | Glass formulations comprising steroid dimers and uses thereof |
CA3176134A1 (en) | 2020-05-01 | 2021-11-04 | Ripple Therapeutics Corporation | Heterodimer compositions and methods for the treatment of ocular disorders |
Family Cites Families (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE288387C (US07794700-20100914-C00152.png) | ||||
DE288311C (US07794700-20100914-C00152.png) | 1915-10-27 | |||
US4062855A (en) | 1971-09-27 | 1977-12-13 | University Of Washington | Synthetic polymers furnishing controlled release of a biologically active component during degradation |
US4363815A (en) * | 1975-07-23 | 1982-12-14 | Yu Ruey J | Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions |
US4287174A (en) * | 1978-03-31 | 1981-09-01 | The Proctor & Gamble Company | Anti-ulcer composition |
US4298595A (en) * | 1978-12-20 | 1981-11-03 | Dynapol | Pharmaceutical preparations containing a polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract |
US4757128A (en) | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
US4906474A (en) | 1983-03-22 | 1990-03-06 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
US4888176A (en) | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
US4483854A (en) * | 1983-04-12 | 1984-11-20 | Key Pharmaceuticals, Inc. | Systemic treatment of psoriasis using certain salicylates |
IL68965A (en) * | 1983-06-13 | 1987-02-27 | Rafa Labor Ltd | Topical pharmaceutical preparation comprising acetylsalicylic acid for the treatment of dermatological disorders |
US4612302A (en) | 1983-11-14 | 1986-09-16 | Brigham And Women's Hospital | Clinical use of somatostatin analogues |
US4886870A (en) * | 1984-05-21 | 1989-12-12 | Massachusetts Institute Of Technology | Bioerodible articles useful as implants and prostheses having predictable degradation rates |
US4891225A (en) | 1984-05-21 | 1990-01-02 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
US4684620A (en) | 1984-09-04 | 1987-08-04 | Gibson-Stephens Neuropharmaceuticals, Inc. | Cyclic polypeptides having mu-receptor specificity |
CH666185A5 (en) * | 1985-09-16 | 1988-07-15 | Dieter Dr Russmann | Salicylic acid or sodium salt - used for treating inflammatory intestinal disorders |
CH671402A5 (US07794700-20100914-C00152.png) | 1985-10-02 | 1989-08-31 | Sandoz Ag | |
DE3670206D1 (de) | 1986-05-20 | 1990-05-17 | Massachusetts Inst Technology | Bioerodierbare erzeugnisse zur verwendung als implantate oder prothese mit einem voraussehbaren resorbierungsgrad. |
US6024983A (en) | 1986-10-24 | 2000-02-15 | Southern Research Institute | Composition for delivering bioactive agents for immune response and its preparation |
US5055524A (en) * | 1987-07-16 | 1991-10-08 | Ppg Industries, Inc. | Polyol-modified polyanhydride curing agent for polyepoxide powder coatings |
US4916204A (en) * | 1987-07-31 | 1990-04-10 | Massachusetts Institute Of Technology | Pure polyanhydride from dicarboxylic acid and coupling agent |
US4857311A (en) | 1987-07-31 | 1989-08-15 | Massachusetts Institute Of Technology | Polyanhydrides with improved hydrolytic degradation properties |
US5259968A (en) | 1988-02-29 | 1993-11-09 | Exxon Chemical Patents Inc. | Dispersant additive comprising the reaction product of a polyanhydride and a mannich condensation product |
US4868274A (en) | 1988-05-23 | 1989-09-19 | Hoechst Celanese Corp. | Polyanhydride from carboxy aryloxy alkanoic acid |
US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
US5356630A (en) | 1989-02-22 | 1994-10-18 | Massachusetts Institute Of Technology | Delivery system for controlled release of bioactive factors |
AU5287090A (en) | 1989-02-28 | 1990-09-26 | Marc N. Benhuri | Method and composition for treatment of periodontal disease |
US4999417A (en) | 1989-03-30 | 1991-03-12 | Nova Pharmaceutical Corporation | Biodegradable polymer compositions |
DK339289D0 (da) * | 1989-07-07 | 1989-07-07 | Dak Lab As | Farmaceutisk praeparat |
US5487897A (en) | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
US4997904A (en) | 1989-08-25 | 1991-03-05 | Nova Pharmaceutical Corporation | Aromatic polyanhydride compositions |
AU655762B2 (en) | 1989-12-26 | 1995-01-12 | Nova Pharmaceutical Corporation | Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use |
US5660851A (en) * | 1989-12-26 | 1997-08-26 | Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem | Ocular inserts |
US5175235A (en) | 1990-06-04 | 1992-12-29 | Nova Pharmaceutical Corporation | Branched polyanhydrides |
US5317079A (en) * | 1990-01-19 | 1994-05-31 | Nova Pharmaceutical Corporation | Fatty acid terminated polyanhydride |
NL9000237A (nl) | 1990-01-31 | 1991-08-16 | Re Novative Drugs For Dermatol | Topicale farmaceutische composities voor de mondholte en vagina. |
US5082925A (en) | 1990-08-16 | 1992-01-21 | Ethicon, Inc. | Homopolymers and copolymers of salicylate lactones |
ATE152147T1 (de) | 1990-11-19 | 1997-05-15 | Cornell Res Foundation Inc | Hyperverzweigte polyester |
US5198572A (en) * | 1991-02-04 | 1993-03-30 | General Electric Company | Copolymers of dicarboxylic acids and salicylic acids |
US5151415A (en) * | 1991-05-23 | 1992-09-29 | Dallas Sirany | Method of treating a papova-type viral infection |
US5264540A (en) | 1992-07-20 | 1993-11-23 | Ethicon, Inc. | Aromatic polyanhydrides |
US5516793A (en) * | 1993-04-26 | 1996-05-14 | Avon Products, Inc. | Use of ascorbic acid to reduce irritation of topically applied active ingredients |
GB9400163D0 (en) | 1994-01-06 | 1994-03-02 | Geistlich Soehne Ag | Membrane |
KR100481565B1 (ko) * | 1994-07-22 | 2005-09-30 | 꼴레띠까 | 친유성히드록시산,그의화장제및약제학적용도및그의제조방법 |
US5902110A (en) | 1995-12-18 | 1999-05-11 | The Block Drug Company | Bone regeneration |
WO1997029778A2 (en) * | 1996-02-15 | 1997-08-21 | Santerre J Paul | Bioresponsive pharmacologically-active polymers and articles made therefrom |
US5837680A (en) * | 1996-02-16 | 1998-11-17 | Children's Medical Center Corporation | Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis |
US5902599A (en) | 1996-02-20 | 1999-05-11 | Massachusetts Institute Of Technology | Biodegradable polymer networks for use in orthopedic and dental applications |
IE960308A1 (en) | 1996-04-23 | 1997-11-05 | Kinerton Ltd | Sustained release ionic conjugate |
US5955096A (en) * | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
JP4410857B2 (ja) | 1997-02-18 | 2010-02-03 | ラットガーズ ザ ステイト ユニヴァーシティ | ヒドロキシ酸から誘導されたモノマー及びそれから調製されたポリマー |
WO1999007382A1 (en) * | 1997-08-06 | 1999-02-18 | Smithkline Beecham Corporation | Macrophage scavenger receptor antagonists for use in the treatment of cardiovascular diseases |
US6486214B1 (en) * | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
US6468519B1 (en) * | 1997-09-10 | 2002-10-22 | Rutgers, The State University Of New Jersey | Polyanhydrides with biologically active degradation products |
ATE378364T1 (de) | 1997-09-10 | 2007-11-15 | Univ Rutgers | Polyamhydride mit therapeutisch verwendbaren abbauprodukten |
US5882665A (en) * | 1997-11-18 | 1999-03-16 | Elizabeth Arden Co., Division Of Conopco, Inc. | Phytosphingosine salicylates in cosmetic compositions |
DE19754063A1 (de) | 1997-12-05 | 1999-06-10 | Bayer Ag | Abbau von biologisch abbaubaren Polymeren |
US6060212A (en) * | 1998-06-11 | 2000-05-09 | Clariant Finance (Bvi) Limited | 193 nm positive-working photoresist composition |
US6153212A (en) * | 1998-10-02 | 2000-11-28 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same |
US20040038948A1 (en) * | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
US6685928B2 (en) * | 1999-12-07 | 2004-02-03 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
US6602915B2 (en) * | 2000-07-27 | 2003-08-05 | Rutgers, The State University Of New Jersey | Therapeutic azo-compounds for drug delivery |
CA2771263A1 (en) * | 2000-07-27 | 2002-02-07 | Rutgers, The State University | Therapeutic polyesters and polyamides |
US20040096476A1 (en) * | 2002-07-17 | 2004-05-20 | Uhrich Kathryn E. | Therapeutic devices for patterned cell growth |
-
1999
- 1999-10-21 US US09/422,294 patent/US6468519B1/en not_active Expired - Fee Related
-
2000
- 2000-10-11 AU AU78771/00A patent/AU7877100A/en not_active Abandoned
- 2000-10-11 WO PCT/US2000/027962 patent/WO2001028492A2/en active IP Right Grant
- 2000-10-11 DE DE60025272T patent/DE60025272D1/de not_active Expired - Lifetime
- 2000-10-11 CA CA002387558A patent/CA2387558A1/en not_active Abandoned
- 2000-10-11 JP JP2001531088A patent/JP2003511550A/ja active Pending
- 2000-10-11 MX MXPA02003890A patent/MXPA02003890A/es active IP Right Grant
- 2000-10-11 EP EP00968928A patent/EP1246627B1/en not_active Expired - Lifetime
- 2000-10-11 AT AT00968928T patent/ATE314078T1/de not_active IP Right Cessation
- 2000-10-11 EP EP04007101A patent/EP1464673A3/en not_active Withdrawn
-
2002
- 2002-09-24 US US10/254,191 patent/US20030035787A1/en not_active Abandoned
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2003511550A5 (US07794700-20100914-C00152.png) | ||
JP2002533472A5 (US07794700-20100914-C00152.png) | ||
EP1702597A3 (en) | Drug delivery of phase changing formulation | |
ES2189874T3 (es) | Dinucleotidos utiles para el tratamiento de enfermedades pulmonares. | |
EP1428821A8 (en) | Piperidin-4-yl amines with analgesic effect | |
JP2002519434A5 (US07794700-20100914-C00152.png) | ||
EP1153924A3 (en) | Substituted 1,3-oxathiolanes with antiviral properties | |
ATE390414T1 (de) | Arzneimittelwirkstoffe mit zwei kovalent verknüpften wirkstoffgruppen (natriumkanalblocker/p2y2 rezeptor agonist) zur behandlung von schleimhäuten | |
CY2575B1 (en) | Improved denture adhesive composition | |
EP2289521A3 (en) | Compositions and methods for use in tergeting vascular destruction | |
JP2003530368A5 (US07794700-20100914-C00152.png) | ||
JP2005519985A5 (US07794700-20100914-C00152.png) | ||
PL362208A1 (en) | Rhinological agents | |
JP2002518170A5 (US07794700-20100914-C00152.png) | ||
JP2003532640A5 (US07794700-20100914-C00152.png) | ||
JP2003509360A5 (US07794700-20100914-C00152.png) | ||
JP2002506864A5 (US07794700-20100914-C00152.png) | ||
JP2003520208A5 (US07794700-20100914-C00152.png) | ||
TW367326B (en) | Pyrimidine derivative, process for the preparation thereof and a pharmaceutical composition containing same | |
JP2002540119A5 (US07794700-20100914-C00152.png) | ||
JP2003521457A5 (US07794700-20100914-C00152.png) | ||
EP1149826A3 (en) | Ester compounds having alicyclic structure, and methods for preparing the same | |
EP0308983A3 (en) | Nmr imaging with mn(ii) coordination compositions | |
NZ332497A (en) | Pharmaceutical composition having a carrier system containing a combination of an alkylene glycol and unsaturated fatty acid alcohol as the solvent and a stiffening agent | |
JPH0597697A (ja) | 歯槽骨再生剤 |