JP2003511399A - 女性避妊薬の成分としてのメソプロゲスチン（プロゲステロン受容体モジュレーター） - Google Patents

女性避妊薬の成分としてのメソプロゲスチン（プロゲステロン受容体モジュレーター）

Info

Publication number
JP2003511399A
JP2003511399A JP2001529395A JP2001529395A JP2003511399A JP 2003511399 A JP2003511399 A JP 2003511399A JP 2001529395 A JP2001529395 A JP 2001529395A JP 2001529395 A JP2001529395 A JP 2001529395A JP 2003511399 A JP2003511399 A JP 2003511399A
Authority
JP
Japan
Prior art keywords
mesoprogestin
estrogen
days
estradiol
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001529395A
Other languages
English (en)
Japanese (ja)
Inventor
シュバリツ，クリストフ
エルガー，バルター
シューベルト，ゲルト
Original Assignee
イエナファルム ゲゼルシャフト ミット ベシュレクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by イエナファルム ゲゼルシャフト ミット ベシュレクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト filed Critical イエナファルム ゲゼルシャフト ミット ベシュレクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト
Publication of JP2003511399A publication Critical patent/JP2003511399A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2001529395A 1999-08-31 2000-08-31 女性避妊薬の成分としてのメソプロゲスチン（プロゲステロン受容体モジュレーター） Pending JP2003511399A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38613399A 1999-08-31 1999-08-31
US09/386,133 1999-08-31
PCT/IB2000/002053 WO2001026603A2 (en) 1999-08-31 2000-08-31 Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives

Publications (1)

Publication Number Publication Date
JP2003511399A true JP2003511399A (ja) 2003-03-25

Family

ID=23524305

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001529395A Pending JP2003511399A (ja) 1999-08-31 2000-08-31 女性避妊薬の成分としてのメソプロゲスチン（プロゲステロン受容体モジュレーター）

Country Status (28)

Country Link
EP (1) EP1605949A2 (no)
JP (1) JP2003511399A (no)
KR (1) KR20020038745A (no)
CN (1) CN1384748A (no)
AR (1) AR025455A1 (no)
AU (1) AU781835B2 (no)
BG (1) BG106441A (no)
BR (1) BR0013711A (no)
CA (1) CA2383650A1 (no)
CO (1) CO5190694A1 (no)
CZ (1) CZ2002707A3 (no)
EA (1) EA006805B1 (no)
EE (1) EE200200103A (no)
HR (1) HRP20020265A2 (no)
HU (1) HUP0202515A3 (no)
IL (1) IL148415A0 (no)
LT (1) LT5001B (no)
LV (1) LV12940B (no)
MX (1) MXPA02002186A (no)
NO (1) NO20020998L (no)
NZ (1) NZ517470A (no)
PE (1) PE20010579A1 (no)
PL (1) PL353994A1 (no)
SI (1) SI20853A (no)
SK (1) SK2982002A3 (no)
UA (1) UA77150C2 (no)
WO (1) WO2001026603A2 (no)
YU (1) YU13902A (no)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006525358A (ja) * 2003-05-02 2006-11-09 ドゥラメド ファーマシューティカルズ， インコーポレイテッド 長期周期避妊養生法を利用するホルモン治療の方法
JP2007530552A (ja) * 2004-03-24 2007-11-01 タツプ・フアーマシユーテイカル・プロダクツ・インコーポレイテツド 逐次ｓｐｒｍ／プロゲスチン治療
JP2009512658A (ja) * 2005-10-19 2009-03-26 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 予防用要求次第ホルモン避妊方法
JP2012523446A (ja) * 2009-04-14 2012-10-04 ラボラトワール・アシュエールア−ファルマ オンデマンド避妊方法
JP2013040181A (ja) * 2004-07-07 2013-02-28 Wyeth Llc 周期的プロゲスチンレジメン及びキット

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE50304970D1 (de) * 2002-08-02 2006-10-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper aktivität für die weibliche fertilitätskontrolle und hormonersatztherapie
DE10236405A1 (de) 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
CN110548034A (zh) * 2019-07-12 2019-12-10 广州莎蔓生物科技有限公司 一种怀孕阻断药物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2054271A (en) 1932-05-17 1936-09-15 Schering Kahlbaum Ag Production of crystallized hormone esters
DE699310C (de) 1936-11-20 1940-11-27 Chemische Ind Ges Verfahren zur Herstellung von in 3-Stellung veresterten Verbindungen vom Typus des Oestradiols
US2225419A (en) 1937-03-01 1940-12-17 Schering Corp Process for the conversion of 17-cisalcohols of the cyclopentanopolyhydrophenanthrene series into the corresponding 17-trans-alcohols
US2611773A (en) 1951-08-21 1952-09-23 Upjohn Co Estradiol 17-cyclopenetanepropionate
US2990414A (en) 1957-03-26 1961-06-27 Syntex Sa 17-undecenoate of estradiol
DE3337450A1 (de) 1983-10-12 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandine und antigestagene fuer den schwangerschaftsabbruch
FI101601B (fi) * 1987-09-24 1998-07-31 Jencap Res Ltd Ehkäisyvalmiste sekä estrogeenin ja progestiinin käyttö ehkäisyvalmist een valmistusmenetelmässä
US5439913A (en) 1992-05-12 1995-08-08 Schering Aktiengesellschaft Contraception method using competitive progesterone antagonists and novel compounds useful therein
US5516769A (en) 1993-02-19 1996-05-14 The Medical College Of Hampton Roads Method of inhibiting fertilization
DE4332284C2 (de) * 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4447715C2 (de) 1994-08-09 1998-02-05 Jenapharm Gmbh Verwendung von Estra-1,3,5(10)-trien-Derivaten zur hormonalen Behandlung von Prostatakarzinomen
DE4429397C2 (de) 1994-08-09 2003-11-20 Jenapharm Gmbh Estra-1,3,5(10)-trien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
AU707235B2 (en) * 1994-10-24 1999-07-08 Schering Aktiengesellschaft Competitive progesterone antagonists for demand-oriented female birth control
US6040340A (en) * 1996-05-07 2000-03-21 Schering Aktiengesellschaft Implantation rates after in vitro fertilization, treatment of infertility and early pregnancy loss with a nitric oxide donor alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors
KR20000022189A (ko) * 1996-06-25 2000-04-25 에프.지.엠. 헤르만스;이.에이치. 리링크 프로제스토젠-항프로제스토젠 섭생
WO1998005679A2 (en) * 1996-08-05 1998-02-12 Duke University Mixed agonists of the progesterone receptor and assays therefor
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
CN1353717A (zh) * 1999-05-04 2002-06-12 莱加制药公司 四环黄体酮受体调节剂化合物及其方法

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006525358A (ja) * 2003-05-02 2006-11-09 ドゥラメド ファーマシューティカルズ， インコーポレイテッド 長期周期避妊養生法を利用するホルモン治療の方法
JP2007530552A (ja) * 2004-03-24 2007-11-01 タツプ・フアーマシユーテイカル・プロダクツ・インコーポレイテツド 逐次ｓｐｒｍ／プロゲスチン治療
JP2013040181A (ja) * 2004-07-07 2013-02-28 Wyeth Llc 周期的プロゲスチンレジメン及びキット
JP2009512658A (ja) * 2005-10-19 2009-03-26 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 予防用要求次第ホルモン避妊方法
JP2012523446A (ja) * 2009-04-14 2012-10-04 ラボラトワール・アシュエールア−ファルマ オンデマンド避妊方法
JP2016188232A (ja) * 2009-04-14 2016-11-04 ラボラトワール・アシュエールア−ファルマＬａｂｏｒａｔｏｉｒｅ Ｈｒａ−Ｐｈａｒｍａ オンデマンド避妊方法

Also Published As

Publication number Publication date
CZ2002707A3 (cs) 2002-11-13
BR0013711A (pt) 2002-05-07
SI20853A (sl) 2002-10-31
WO2001026603A2 (en) 2001-04-19
BG106441A (bg) 2002-09-30
EA006805B1 (ru) 2006-04-28
CN1384748A (zh) 2002-12-11
YU13902A (sh) 2006-01-16
HUP0202515A3 (en) 2004-06-28
HUP0202515A2 (hu) 2002-12-28
EE200200103A (et) 2003-04-15
PE20010579A1 (es) 2001-06-04
AR025455A1 (es) 2002-11-27
LT2002035A (lt) 2002-10-25
UA77150C2 (en) 2006-11-15
NO20020998L (no) 2002-03-14
WO2001026603A3 (en) 2002-01-17
MXPA02002186A (es) 2002-09-02
PL353994A1 (en) 2003-12-15
CO5190694A1 (es) 2002-08-29
LV12940B (en) 2003-06-20
EA200200284A1 (ru) 2002-10-31
LT5001B (lt) 2003-03-25
AU781835B2 (en) 2005-06-16
NZ517470A (en) 2004-03-26
EP1605949A2 (en) 2005-12-21
CA2383650A1 (en) 2001-04-19
NO20020998D0 (no) 2002-02-28
HRP20020265A2 (en) 2004-02-29
IL148415A0 (en) 2002-09-12
AU3215001A (en) 2001-04-23
KR20020038745A (ko) 2002-05-23
SK2982002A3 (en) 2002-07-02

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