JP2003509468A - 癒着形成を阻害する方法および組成物 - Google Patents
癒着形成を阻害する方法および組成物Info
- Publication number
- JP2003509468A JP2003509468A JP2001524620A JP2001524620A JP2003509468A JP 2003509468 A JP2003509468 A JP 2003509468A JP 2001524620 A JP2001524620 A JP 2001524620A JP 2001524620 A JP2001524620 A JP 2001524620A JP 2003509468 A JP2003509468 A JP 2003509468A
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- antagonist molecule
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- monoclonal antibody
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/045—Gelatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/256—Antibodies, e.g. immunoglobulins, vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/424—Anti-adhesion agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/432—Inhibitors, antagonists
- A61L2300/436—Inhibitors, antagonists of receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40552299A | 1999-09-23 | 1999-09-23 | |
| US09/405,522 | 1999-09-23 | ||
| PCT/US2000/026095 WO2001021196A1 (en) | 1999-09-23 | 2000-09-22 | Method and compositions for inhibiting adhesion formation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003509468A true JP2003509468A (ja) | 2003-03-11 |
| JP2003509468A5 JP2003509468A5 (enExample) | 2007-11-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001524620A Pending JP2003509468A (ja) | 1999-09-23 | 2000-09-22 | 癒着形成を阻害する方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1223962A4 (enExample) |
| JP (1) | JP2003509468A (enExample) |
| KR (1) | KR20020048941A (enExample) |
| CN (1) | CN1399554A (enExample) |
| AU (1) | AU781442B2 (enExample) |
| BR (1) | BR0014222A (enExample) |
| CA (1) | CA2384812A1 (enExample) |
| MX (1) | MXPA02003079A (enExample) |
| WO (1) | WO2001021196A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019138583A1 (ja) * | 2018-01-15 | 2019-07-18 | 持田製薬株式会社 | 癒着防止用組成物 |
| US11464597B2 (en) | 2016-07-13 | 2022-10-11 | The University Of Tokyo | Adhesion-preventing composition |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2025685B1 (en) | 2007-08-15 | 2013-06-19 | Canadian Blood Services | Monoclonal antibodies against BETA3 integrins |
| KR102318958B1 (ko) * | 2019-08-08 | 2021-10-27 | 고려대학교 산학협력단 | 인테그린 α2β1 억제제를 유효성분으로 포함하는 조직 유착 예방 또는 치료용 약제학적 조성물 |
| US20230149503A1 (en) * | 2020-03-31 | 2023-05-18 | The Regents Of The University Of California | Compositions and methods for treating dysregulated wound healing |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE901736L (en) * | 1989-05-17 | 1990-11-17 | Fuller H B Licensing Financ | Polypeptide-antibody conjugate for inhibiting cell adhesion |
| US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| CA2302017C (en) * | 1997-08-25 | 2007-01-30 | Harold Brem | Prevention of adhesions and excessive scar formation using angiogenesis inhibitors |
-
2000
- 2000-09-22 MX MXPA02003079A patent/MXPA02003079A/es unknown
- 2000-09-22 WO PCT/US2000/026095 patent/WO2001021196A1/en not_active Ceased
- 2000-09-22 KR KR1020027003796A patent/KR20020048941A/ko not_active Ceased
- 2000-09-22 BR BR0014222-0A patent/BR0014222A/pt not_active IP Right Cessation
- 2000-09-22 JP JP2001524620A patent/JP2003509468A/ja active Pending
- 2000-09-22 AU AU79850/00A patent/AU781442B2/en not_active Ceased
- 2000-09-22 EP EP00970476A patent/EP1223962A4/en not_active Withdrawn
- 2000-09-22 CA CA002384812A patent/CA2384812A1/en not_active Abandoned
- 2000-09-22 CN CN00816148A patent/CN1399554A/zh active Pending
Non-Patent Citations (1)
| Title |
|---|
| JPN6010045316, Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ, 1987, ｖｏｌ．２６２， ｎｏ．３６, ｐ．１７７０３−１７７１１ * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11464597B2 (en) | 2016-07-13 | 2022-10-11 | The University Of Tokyo | Adhesion-preventing composition |
| US11890145B2 (en) | 2016-07-13 | 2024-02-06 | The University Of Tokyo | Adhesion-preventing composition |
| WO2019138583A1 (ja) * | 2018-01-15 | 2019-07-18 | 持田製薬株式会社 | 癒着防止用組成物 |
| JPWO2019138583A1 (ja) * | 2018-01-15 | 2021-01-28 | 持田製薬株式会社 | 癒着防止用組成物 |
| JP7161496B2 (ja) | 2018-01-15 | 2022-10-26 | 持田製薬株式会社 | 癒着防止用組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU781442B2 (en) | 2005-05-26 |
| WO2001021196A1 (en) | 2001-03-29 |
| CA2384812A1 (en) | 2001-03-29 |
| CN1399554A (zh) | 2003-02-26 |
| KR20020048941A (ko) | 2002-06-24 |
| AU7985000A (en) | 2001-04-24 |
| BR0014222A (pt) | 2003-02-25 |
| EP1223962A1 (en) | 2002-07-24 |
| MXPA02003079A (es) | 2004-04-21 |
| EP1223962A4 (en) | 2004-01-21 |
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