JP2003506014A - エネルギー移動を使用する亜細胞条件およびプロセスをアッセイするための組成物および方法 - Google Patents

エネルギー移動を使用する亜細胞条件およびプロセスをアッセイするための組成物および方法

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Publication number
JP2003506014A
JP2003506014A JP2001505191A JP2001505191A JP2003506014A JP 2003506014 A JP2003506014 A JP 2003506014A JP 2001505191 A JP2001505191 A JP 2001505191A JP 2001505191 A JP2001505191 A JP 2001505191A JP 2003506014 A JP2003506014 A JP 2003506014A
Authority
JP
Japan
Prior art keywords
energy transfer
molecule
mitochondrial
energy
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001505191A
Other languages
English (en)
Japanese (ja)
Inventor
ジェイムス エイ． ディケンズ，
ゴーナル ヴェリセレビ，
サミトラ エス． ゴーシュ，
Original Assignee
マイトコー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/338,122 external-priority patent/US6323039B1/en
Application filed by マイトコー filed Critical マイトコー
Publication of JP2003506014A publication Critical patent/JP2003506014A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
    • G01N33/5079—Mitochondria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2001505191A 1999-06-22 2000-06-22 エネルギー移動を使用する亜細胞条件およびプロセスをアッセイするための組成物および方法 Withdrawn JP2003506014A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US14043399P 1999-06-22 1999-06-22
US60/140,433 1999-06-22
US09/338,122 US6323039B1 (en) 1999-06-22 1999-06-22 Compositions and methods for assaying subcellular conditions and processes using energy transfer
US09/338,122 1999-06-22
US17638300P 2000-01-14 2000-01-14
US60/176,383 2000-01-14
PCT/US2000/017380 WO2000079274A2 (en) 1999-06-22 2000-06-22 Methods for assaying subcellular conditions using energy transfer

Publications (1)

Publication Number Publication Date
JP2003506014A true JP2003506014A (ja) 2003-02-18

Family

ID=27385499

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001505191A Withdrawn JP2003506014A (ja) 1999-06-22 2000-06-22 エネルギー移動を使用する亜細胞条件およびプロセスをアッセイするための組成物および方法

Country Status (5)

Country Link
EP (1) EP1210596A2 (de)
JP (1) JP2003506014A (de)
AU (1) AU5763600A (de)
CA (1) CA2375542A1 (de)
WO (1) WO2000079274A2 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010090265A1 (ja) 2009-02-06 2010-08-12 国立大学法人北海道大学 蛍光ソルバトクロミック色素
WO2019093379A1 (ja) * 2017-11-07 2019-05-16 学校法人自治医科大学 ミトコンドリアの機能障害の改善剤、及びミトコンドリアの機能障害に起因する疾患又は症状の予防又は治療薬、並びにそれらの用途

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ296799A0 (en) 1999-09-20 1999-10-14 Unisearch Limited A cell-membrane impermeable trivalent organoarsenical derivative and use thereof
US6287758B1 (en) * 2000-03-23 2001-09-11 Axiom Biotechnologies, Inc. Methods of registering trans-membrane electric potentials
AUPR537101A0 (en) * 2001-05-31 2001-06-28 International Diabetes Institute A method of assessment and treatment
WO2003015703A2 (en) * 2001-08-15 2003-02-27 The Regents Of The University Of Michigan Compositions and methods relating to novel benzodiazepine compounds and targets thereof
ES2330519T3 (es) 2002-11-07 2009-12-11 Newsouth Innovations Pty Limited Inducion de la transicion de permeabilidad mitocondrial.
EP1760158B1 (de) * 2004-05-18 2013-07-17 Mitsubishi Tanabe Pharma Corporation Verfahren zum testen einer zur änderung des mitochondrialen membranpotentials fähigen substanz
EP2069371B1 (de) 2006-11-01 2013-03-13 NewSouth Innovations Pty Limited Organo-arsenoxid-verbindungen und deren verwendung
EP2551352B1 (de) * 2010-03-25 2016-09-14 National University Corporation University Of Toyama Fluoreszierende sonde zur identifikation und isolation von plasmazellen sowie verfahren zur identifikation und isolation von plasmazellen mithilfe dieser sonde
EP2995948A1 (de) * 2014-09-09 2016-03-16 Ecole Polytechnique Federale de Lausanne (EPFL) Verfahren und Verbindungen für hämatopoetische Stammzellenmedizin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5661035A (en) * 1995-06-07 1997-08-26 The Regents Of The University Of California Voltage sensing by fluorescence resonance energy transfer

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010090265A1 (ja) 2009-02-06 2010-08-12 国立大学法人北海道大学 蛍光ソルバトクロミック色素
WO2019093379A1 (ja) * 2017-11-07 2019-05-16 学校法人自治医科大学 ミトコンドリアの機能障害の改善剤、及びミトコンドリアの機能障害に起因する疾患又は症状の予防又は治療薬、並びにそれらの用途
US11369615B2 (en) 2017-11-07 2022-06-28 Jichi Medical University Agent for improving mitochondrial dysfunction, preventative or therapeutic agent for diseases or symptoms caused by mitochondrial dysfunction, and applications therefor

Also Published As

Publication number Publication date
AU5763600A (en) 2001-01-09
WO2000079274A2 (en) 2000-12-28
EP1210596A2 (de) 2002-06-05
WO2000079274A3 (en) 2002-01-10
CA2375542A1 (en) 2000-12-28

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Legal Events

Date Code Title Description
A300 Withdrawal of application because of no request for examination

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 20070904