CA2375542A1 - Compositions and methods for assaying subcellular conditions and processes energy transfer - Google Patents

Compositions and methods for assaying subcellular conditions and processes energy transfer Download PDF

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Publication number
CA2375542A1
CA2375542A1 CA002375542A CA2375542A CA2375542A1 CA 2375542 A1 CA2375542 A1 CA 2375542A1 CA 002375542 A CA002375542 A CA 002375542A CA 2375542 A CA2375542 A CA 2375542A CA 2375542 A1 CA2375542 A1 CA 2375542A1
Authority
CA
Canada
Prior art keywords
energy transfer
molecule
mitochondria
energy
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002375542A
Other languages
English (en)
French (fr)
Inventor
James A. Dykens
Gonul Velicelebi
Soumitra S. Ghosh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Migenix Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/338,122 external-priority patent/US6323039B1/en
Application filed by Individual filed Critical Individual
Publication of CA2375542A1 publication Critical patent/CA2375542A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
    • G01N33/5079—Mitochondria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CA002375542A 1999-06-22 2000-06-22 Compositions and methods for assaying subcellular conditions and processes energy transfer Abandoned CA2375542A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US14043399P 1999-06-22 1999-06-22
US09/338,122 US6323039B1 (en) 1999-06-22 1999-06-22 Compositions and methods for assaying subcellular conditions and processes using energy transfer
US60/140,433 1999-06-22
US09/338,122 1999-06-22
US17638300P 2000-01-14 2000-01-14
US60/176,383 2000-01-14
PCT/US2000/017380 WO2000079274A2 (en) 1999-06-22 2000-06-22 Methods for assaying subcellular conditions using energy transfer

Publications (1)

Publication Number Publication Date
CA2375542A1 true CA2375542A1 (en) 2000-12-28

Family

ID=27385499

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002375542A Abandoned CA2375542A1 (en) 1999-06-22 2000-06-22 Compositions and methods for assaying subcellular conditions and processes energy transfer

Country Status (5)

Country Link
EP (1) EP1210596A2 (de)
JP (1) JP2003506014A (de)
AU (1) AU5763600A (de)
CA (1) CA2375542A1 (de)
WO (1) WO2000079274A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ296799A0 (en) 1999-09-20 1999-10-14 Unisearch Limited A cell-membrane impermeable trivalent organoarsenical derivative and use thereof
US6287758B1 (en) * 2000-03-23 2001-09-11 Axiom Biotechnologies, Inc. Methods of registering trans-membrane electric potentials
AUPR537101A0 (en) * 2001-05-31 2001-06-28 International Diabetes Institute A method of assessment and treatment
MXPA04001421A (es) * 2001-08-15 2004-06-03 Univ Michigan Composiciones y metodos que se relacionan con compuestos novedosos de benzodiazepina y sus destinos.
CN101863958B (zh) * 2002-11-07 2012-07-18 新南创新私人有限公司 对线粒体通透性转换的诱导
WO2005111228A1 (ja) 2004-05-18 2005-11-24 Mitsubishi Pharma Corporation ミトコンドリアの膜電位を変化させる物質の評価方法
WO2008052279A1 (en) 2006-11-01 2008-05-08 Newsouth Innovations Pty Limited Organo-arsenoxide compounds and use thereof
WO2010090265A1 (ja) 2009-02-06 2010-08-12 国立大学法人北海道大学 蛍光ソルバトクロミック色素
CN102947463B (zh) 2010-03-25 2016-01-20 国立大学法人富山大学 浆细胞鉴定和分离用荧光探针以及使用该探针的浆细胞的鉴定或分离方法
EP2995948A1 (de) * 2014-09-09 2016-03-16 Ecole Polytechnique Federale de Lausanne (EPFL) Verfahren und Verbindungen für hämatopoetische Stammzellenmedizin
JP6958860B2 (ja) 2017-11-07 2021-11-02 学校法人自治医科大学 ミトコンドリアの機能障害の改善剤、及びミトコンドリアの機能障害に起因する疾患又は症状の予防又は治療薬、並びにそれらの用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5661035A (en) * 1995-06-07 1997-08-26 The Regents Of The University Of California Voltage sensing by fluorescence resonance energy transfer

Also Published As

Publication number Publication date
WO2000079274A3 (en) 2002-01-10
WO2000079274A2 (en) 2000-12-28
JP2003506014A (ja) 2003-02-18
AU5763600A (en) 2001-01-09
EP1210596A2 (de) 2002-06-05

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Legal Events

Date Code Title Description
FZDE Discontinued