JP2003505409A - 赤血球から薬剤を遊離する方法 - Google Patents

赤血球から薬剤を遊離する方法

Info

Publication number
JP2003505409A
JP2003505409A JP2001511898A JP2001511898A JP2003505409A JP 2003505409 A JP2003505409 A JP 2003505409A JP 2001511898 A JP2001511898 A JP 2001511898A JP 2001511898 A JP2001511898 A JP 2001511898A JP 2003505409 A JP2003505409 A JP 2003505409A
Authority
JP
Japan
Prior art keywords
red blood
blood cells
cells
ultrasound
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001511898A
Other languages
English (en)
Japanese (ja)
Inventor
ロラン・ハロ，アナ・マリア
マクヘイル，アンソニー・パトリック
クレイグ，ロジャー
Original Assignee
ジェンデル・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジェンデル・リミテッド filed Critical ジェンデル・リミテッド
Publication of JP2003505409A publication Critical patent/JP2003505409A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A61K41/0033—Sonodynamic cancer therapy with sonochemically active agents or sonosensitizers, having their cytotoxic effects enhanced through application of ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2001511898A 1999-07-23 2000-07-24 赤血球から薬剤を遊離する方法 Pending JP2003505409A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9917416.1A GB9917416D0 (enExample) 1999-07-23 1999-07-23
GB9917416.1 1999-07-23
US14655699P 1999-07-30 1999-07-30
US60/146,556 1999-07-30
PCT/GB2000/002848 WO2001007011A1 (en) 1999-07-23 2000-07-24 Method for releasing an agent from a red blood cell

Publications (1)

Publication Number Publication Date
JP2003505409A true JP2003505409A (ja) 2003-02-12

Family

ID=10857882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001511898A Pending JP2003505409A (ja) 1999-07-23 2000-07-24 赤血球から薬剤を遊離する方法

Country Status (8)

Country Link
EP (1) EP1196143B1 (enExample)
JP (1) JP2003505409A (enExample)
AT (1) ATE318581T1 (enExample)
AU (1) AU6171000A (enExample)
CA (1) CA2378377A1 (enExample)
GB (1) GB9917416D0 (enExample)
MX (1) MXPA02000792A (enExample)
WO (1) WO2001007011A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017503491A (ja) * 2013-12-20 2017-02-02 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ２以上の疎水性ドメインおよびｐｅｇ部分を含む親水性ドメインを含む化合物の、細胞の安定化のための使用

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0002856D0 (en) * 2000-02-08 2000-03-29 Gendel Limited Ultrasound sensitisation
AU2001272670A1 (en) * 2000-07-24 2002-02-05 Gendel Limited Polypeptide delivery II-2
EP1353723A2 (en) 2000-11-17 2003-10-22 Gendel Limited Ablation of cells using combined electric field and ultrasound therapy
US6821274B2 (en) 2001-03-07 2004-11-23 Gendel Ltd. Ultrasound therapy for selective cell ablation
JP4191998B2 (ja) * 2001-02-19 2008-12-03 ポーラ化成工業株式会社 エレクトロポレーション用の組成物
WO2003099382A1 (en) 2002-05-23 2003-12-04 Gendel Limited Ablation device
ES2708360T3 (es) 2013-12-20 2019-04-09 Hoffmann La Roche Compuestos que comprenden uno o más dominios hidrófobos y un dominio hidrófilo que comprende restos de PEG, útiles para unir células
WO2015091948A1 (en) 2013-12-20 2015-06-25 Roche Diagnostics Gmbh Method of immobilizing a cell on a support using compounds comprising a polyethylene glycol moiety
CN110090309B (zh) * 2019-05-28 2022-05-31 上海大学 功能基化红细胞膜的制备方法
CN113088494B (zh) * 2021-04-13 2022-08-05 武汉大学 一种用于释放被红细胞仿生材料捕获的肿瘤细胞的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2655801C2 (de) * 1976-12-09 1986-06-26 Kernforschungsanlage Jülich GmbH, 5170 Jülich Injizierbare Suspension von Membranvesikeln aus Erythrozyten und Verfahren zur Herstellung der Suspension
US4935223A (en) * 1988-08-04 1990-06-19 Board Of Regents, The University Of Texas System Labeled cells for use in imaging
US5236835A (en) * 1988-10-05 1993-08-17 Hapgood, C.V. Electro insertion of proteins into red cell membranes
JPH02121931A (ja) * 1988-10-29 1990-05-09 Res Inst For Prod Dev 濃縮ヘモグロビンの製造方法
AU725693B2 (en) * 1996-03-12 2000-10-19 Board Of Regents Of The University Of Nebraska, The Targeted site specific drug delivery compositions and method of use
EP0882448B1 (en) * 1997-05-05 2005-01-12 DIDECO S.r.l. Method of encapsulating biologically active agents within erythrocytes and apparatus therefor
DE19735460A1 (de) * 1997-08-16 1999-02-18 Rolf Prof Dr Med Zander Spül- oder Lagerungsflüssigkeit für Blutzellen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017503491A (ja) * 2013-12-20 2017-02-02 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ２以上の疎水性ドメインおよびｐｅｇ部分を含む親水性ドメインを含む化合物の、細胞の安定化のための使用

Also Published As

Publication number Publication date
WO2001007011A1 (en) 2001-02-01
ATE318581T1 (de) 2006-03-15
GB9917416D0 (enExample) 1999-09-22
AU6171000A (en) 2001-02-13
EP1196143B1 (en) 2006-03-01
CA2378377A1 (en) 2001-02-01
EP1196143A1 (en) 2002-04-17
MXPA02000792A (es) 2003-07-14

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