JP2003500010A - 哺乳動物サイトカイン；関連試薬および方法 - Google Patents

哺乳動物サイトカイン；関連試薬および方法

Info

Publication number
JP2003500010A
JP2003500010A JP2000604066A JP2000604066A JP2003500010A JP 2003500010 A JP2003500010 A JP 2003500010A JP 2000604066 A JP2000604066 A JP 2000604066A JP 2000604066 A JP2000604066 A JP 2000604066A JP 2003500010 A JP2003500010 A JP 2003500010A
Authority
JP
Japan
Prior art keywords
amino acids
polypeptide
seq
segment
mature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000604066A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003500010A5 (https=
Inventor
ビルギット・オップマン
ジャクリーン・シー・ティマンズ
ロバート・エイ・カステライン
ジェイ・フェルナンド・バザン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of JP2003500010A publication Critical patent/JP2003500010A/ja
Publication of JP2003500010A5 publication Critical patent/JP2003500010A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000604066A 1999-03-11 2000-03-09 哺乳動物サイトカイン；関連試薬および方法 Pending JP2003500010A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26790199A 1999-03-11 1999-03-11
US09/267,901 1999-03-11
PCT/US2000/006182 WO2000053631A1 (en) 1999-03-11 2000-03-09 Mammalian cytokines; related reagents and methods

Publications (2)

Publication Number Publication Date
JP2003500010A true JP2003500010A (ja) 2003-01-07
JP2003500010A5 JP2003500010A5 (https=) 2007-05-10

Family

ID=23020618

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000604066A Pending JP2003500010A (ja) 1999-03-11 2000-03-09 哺乳動物サイトカイン；関連試薬および方法

Country Status (9)

Country Link
EP (2) EP1159299B1 (https=)
JP (1) JP2003500010A (https=)
AR (1) AR022890A1 (https=)
AT (1) ATE420894T1 (https=)
AU (1) AU3873200A (https=)
CA (1) CA2366706A1 (https=)
DE (1) DE60041393D1 (https=)
ES (1) ES2319958T3 (https=)
WO (1) WO2000053631A1 (https=)

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FR2804435A1 (fr) * 2000-01-27 2001-08-03 Pf Medicament COMPLEXE ISOLE COMPRENANT UNE PROTEINE NNT-1 ET EN OUTRE AU MOINS UNE PROTEINE CLF-1 ET/OU UNE PROTEINE sCNTFRalpha
US7045283B2 (en) * 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
CN101052726A (zh) 2003-05-09 2007-10-10 森托科尔公司 IL－23p40特异性免疫球蛋白衍生蛋白、组合物、方法和用途
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
SI2452694T1 (sl) 2005-06-30 2019-05-31 Janssen Biotech, Inc. Protitelesa proti-IL-23, sestavki in postopki uporabe
PT1931710T (pt) 2005-08-31 2017-03-28 Merck Sharp & Dohme Anticorpos anti-il-23 manipulados
HUE034269T2 (en) 2005-12-29 2018-02-28 Janssen Biotech Inc Human anti-IL-23 antibodies, preparations, methods and applications
ES2708988T3 (es) 2007-02-23 2019-04-12 Merck Sharp & Dohme Anticuerpos anti-IL-23p19 obtenidos por ingeniería genética
JP2010518858A (ja) 2007-02-23 2010-06-03 シェーリング コーポレイション 操作された抗−ｉｌ−２３ｐ１９抗体
CA2679400A1 (en) 2007-02-28 2008-09-04 Schering Corporation Combination therapy for treatment of immune disorders
NZ579251A (en) 2007-02-28 2012-06-29 Schering Corp Engineered anti-il-23r antibodies
ES2729603T3 (es) 2012-06-27 2019-11-05 Merck Sharp & Dohme Anticuerpos IL-23 antihumanos cristalinos
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
JP7382232B2 (ja) 2017-05-02 2023-11-16 メルク・シャープ・アンド・ドーム・エルエルシー 抗ｌａｇ３抗体の製剤および抗ｌａｇ３抗体と抗ｐｄ－１抗体との共製剤
WO2020081408A1 (en) 2018-10-18 2020-04-23 Merck Sharp & Dohme Corp. Formulations of anti-rsv antibodies and methods of use thereof
MX2021004928A (es) 2018-10-31 2021-06-08 Merck Sharp & Dohme Llc Cristales de anticuerpo anti-pd-1 humano y metodos de uso de los mismos.
EP3876990A4 (en) 2018-11-07 2023-09-06 Merck Sharp & Dohme LLC CO-FORMULATIONS OF ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES
IL283192B2 (en) 2018-11-20 2025-10-01 Janssen Biotech Inc A safe and effective method for treating psoriasis with a specific anti-IL-23 antibody
JP7805788B2 (ja) 2019-05-23 2026-01-26 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ－２３及びｔｎｆアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
IL298389A (en) 2020-05-21 2023-01-01 Janssen Biotech Inc Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha

Citations (3)

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WO1998033922A1 (en) * 1997-02-03 1998-08-06 Amgen Inc. The neurotrophic factor nnt-1
WO1999000415A1 (en) * 1997-06-30 1999-01-07 Human Genome Sciences, Inc. Cardiotrophin-like cytokine
JP2001503612A (ja) * 1996-09-11 2001-03-21 アムラド・オペレイションズ・プロプライエタリー・リミテッド 新規ヘモポイエチン受容体およびこれをコードする遺伝子配列

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US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
DE3382317D1 (de) 1982-03-15 1991-07-25 Schering Corp Hybride dns, damit hergestellte bindungszusammensetzung und verfahren dafuer.
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5470952A (en) * 1993-10-20 1995-11-28 Regeneron Pharmaceuticals, Inc. CNTF and IL-6 antagonists
EP0759466B1 (en) * 1995-08-01 2005-12-28 F. Hoffmann-La Roche Ag Low binding affinity interleukin-12 beta receptors
AU5733898A (en) * 1997-01-16 1998-08-07 Genetics Institute Inc. Member of the hematopoietin receptor superfamily
US5741772A (en) * 1997-02-03 1998-04-21 Amgen Inc. Neurotrophic factor NNT-1
WO1998049307A1 (en) * 1997-05-01 1998-11-05 Zymogenetics, Inc. Mammalian cytokine-like receptor
GB9721961D0 (en) * 1997-10-16 1997-12-17 Glaxo Group Ltd Novel molecules
NZ527900A (en) * 1997-12-03 2005-02-25 Genentech Inc PRO361 polypeptides and nucleic acids with homology to mucin and chitinase
AU2454399A (en) * 1998-01-09 1999-07-26 Immunex Corporation H14 dna and polypeptides
WO1999040195A1 (en) * 1998-02-06 1999-08-12 Schering Corporation Mammalian receptor proteins; related reagents and methods
PT1181366E (pt) * 1999-06-01 2009-05-25 Schering Corp Proteínas receptoras de mamífero; reagentes e métodos relacionados
FR2804435A1 (fr) * 2000-01-27 2001-08-03 Pf Medicament COMPLEXE ISOLE COMPRENANT UNE PROTEINE NNT-1 ET EN OUTRE AU MOINS UNE PROTEINE CLF-1 ET/OU UNE PROTEINE sCNTFRalpha

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001503612A (ja) * 1996-09-11 2001-03-21 アムラド・オペレイションズ・プロプライエタリー・リミテッド 新規ヘモポイエチン受容体およびこれをコードする遺伝子配列
WO1998033922A1 (en) * 1997-02-03 1998-08-06 Amgen Inc. The neurotrophic factor nnt-1
WO1999000415A1 (en) * 1997-06-30 1999-01-07 Human Genome Sciences, Inc. Cardiotrophin-like cytokine

Also Published As

Publication number Publication date
EP1159299B1 (en) 2009-01-14
AU3873200A (en) 2000-09-28
ES2319958T3 (es) 2009-05-18
DE60041393D1 (de) 2009-03-05
EP1942114A2 (en) 2008-07-09
EP1159299A1 (en) 2001-12-05
AR022890A1 (es) 2002-09-04
CA2366706A1 (en) 2000-09-14
ATE420894T1 (de) 2009-01-15
EP1942114A3 (en) 2008-08-27
WO2000053631A1 (en) 2000-09-14

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