JP2003267834A - Skin care preparation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a sebum-controlling cosmetic excellent in effect for persistently reducing shininess due to sebum by preventing shininess of the skin and failure of the cosmetic. <P>SOLUTION: The cosmetic contains two or more species of inorganic powder and plant extract. The inorganic powder is one or more species selected from hydroxyapatite, silica, sericite, zinc oxide, titanium oxide, talc and kaolin. The plant extract is the extract of Belamcanda chinensis, Astragalus sinicus, Spindus mukurossi, Camellia sinensis, Crataegus oxyacantha, Glycine max, Phellodendron amurense Rupr., Syzygium aromaticum, Zanthoxylum piper or Rehmannia glutinosa. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention has a persistent and topical sebum-regulating effect on the skin, cosmetics, packs,
The present invention relates to a sebum-controlling cosmetic that can be incorporated into a skin external preparation, shampoo, hair conditioner, hair treatment, hair tonic, hair-growth / hair-nourishing cosmetic, and the like.

[0002]

2. Description of the Related Art Conventionally, the sebum secreted by the sebaceous glands of the skin and scalp keeps the skin soft and smooth, and supplies the necessary and appropriate oil to the hair to maintain its suppleness and beauty. Is necessary for. In addition, sebum plays an important role in preventing various irritants from outside the body from mixing in from the skin and the surface of the scalp, while preventing the loss of water from the skin and the stratum corneum of the scalp.

However, when the activity of the sebaceous glands is excessively increased and the secretion of sebum increases too much, the skin becomes unpleasant, such as shininess, stickiness and makeup loss, and scalp increases dandruff and seborrheic skin. May cause flames and accompanying hair loss. Further, it is known that excessive sebum assists the reproduction of microorganisms and pathogenic bacteria in the skin and scalp, causing various skin troubles.

For the purpose of improving or preventing such cosmetic problems, dermatitis, and skin troubles caused by excessive secretion of sebum, the sebum is removed by washing with soap or the like in order to remove the secreted sebum. Furthermore, it has been practiced to use an inorganic powder having a high sebum absorption effect.
In addition, attempts have been made to use sebum secretion inhibitors to suppress the increase in sebum secretion. As the sebum secretion inhibitor, an antiandrogen agent is known. The anti-androgen agent inhibits either or both of the activity of the 5α-reductase enzyme involved in the reduction of testosterone from dihydrotestosterone and the binding of dihydrotestosterone with the receptor. Vitamin A acid and the like are known as other sebum secretion inhibitors.

However, sebum absorption by hydroxyapatite and zinc oxide, which has been proposed as a method of removing excess sebum by washing the skin and scalp with the above-mentioned soap or the like and using inorganic powder (Japanese Patent Laid-Open No. 2002-20218) However, since the effect is temporary, there is a problem that the excess secretion of sebum cannot be suppressed to fundamentally improve the dermatitis, skin troubles and the like caused by the excess secretion of sebum.

On the other hand, the anti-androgen is a substance involved in hormone metabolism, and the vitamin A acid also has a hormone-like action. Since these act on organs other than the sebaceous glands, there is a problem in that they have systemic side effects rather than local effects.

In order to solve such a problem, it has astringent effect for the purpose of tightening pores as well as a cosmetic (special 2791673) containing isoflavone having a mild anti-androgen-like action. Cosmetics containing a sulfated polysaccharide (JP-A-12-169322) and the like have been proposed, but the effect was not sufficient.

[0008]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a sebum-regulating cosmetic composition which has an excellent effect of suppressing sebum on the skin and maintaining a non-greasy state due to sebum for a long time.

[0009]

[Means for Solving the Problems] The present inventors have found that a cosmetic composition comprising a combination of two or more kinds of inorganic powder and plant extract can suppress sebum and maintain a non-greasy state for sebum for a long time. Then, the present invention has been completed.

That is, the present invention is: 1. A sebum-regulating cosmetic composition containing two or more kinds of inorganic powder and plant extract, The inorganic powder is one or more selected from hydroxyapatite, silica, sericite, zinc oxide, titanium oxide, talc and kaolin,
2. The sebum-controlling cosmetic according to 1, and 3. 1. The cosmetic composition according to 1 or 2, wherein the plant extract is an extract of Hyogi, Astragalus mexicanus, Scutellariae japonica, Tea tree, Hawthorn, Soybean, Oat, Clove, Hawthorn and Zyou.

[0011]

BEST MODE FOR CARRYING OUT THE INVENTION The inorganic powder used in the present invention is not particularly limited as long as it can be blended in cosmetics and external preparations for skin, and specifically, hydroxyapatite, silica, sericite, Zinc oxide, titanium oxide,
Kaolin and talc are exemplified. Further, the particle shape of these inorganic powders is not particularly limited, and may be, for example, any of granular, spherical, plate-like, needle-like, petal-like, and the average particle diameter is not particularly limited, but 0.001 to 20 μm is preferable. .
The compounding amount is also not particularly limited, but it is suitable to be about 0.0001 to 30% by mass. If it is less than 0.0001% by mass, the amount of sebum adsorbed may be insufficient, which may be insufficient to obtain the expected sebum control effect. Further, even if it exceeds 30% by mass, slippage on the skin may be deteriorated, which may cause a problem that it is not preferable in use. In the sebum control cosmetic of the present invention, it is particularly preferable to use hydroxyapatite as the inorganic powder.

The hydroxyapatite used in the present invention is not particularly limited and is defined as calcium phosphate having an apatite structure at Ca / P = 0.5 to 2.0 (molar ratio) (Fr.
agrance Journal, p144-148, January 1999 issue). Commercially available from Miyoshi Kasei "Powder La Vi
e ”,“ HAP-100 ”commercially available from Taihei Chemical Industry Co., Ltd.,
"HAP-200" etc. can be used.

As the plant extract, various plant extracts to be incorporated into cosmetics and external preparations for skin can be used. Specific examples include extracts of Hyogi, Astragalus japonicus, Saprose, Tea tree, Hawthorn, Soybean, Oat, Clove, Clam, Hawthorn and Dioscorea.

As a plant of the respective extracts, Scutellaria baicalensis (Belamcanda chin) from the family Iridaceae is used.
ensis.), Astragalus sinicus of the leguminous family (Leguminosae) is used for astragalus, and Sapindus mukuros of the Sapindaceae is a
si Gaertn.), Tea tree is the Camellia (Theaceae) tea tree (Thea sinensiss Linne), Hawthorn is the Rosaceae (Rosaceae) Hawthorn (Crataeus
oxyacantha L.) can be used. Soybean is a legume (Leg
uminosae) soybean (Glycine hirsta Maxim.), and psyllium (Rutaceae) rhubarb (Phellodend)
ron amurense Ruprecht), Clove is a clove (Syzygium aromaticum Merr) of the Myrtaceae family.
ill et Perry), the salamander is a citrus family (Rutacea
e) salmon (Zanthoxylum piperitum (L.) DC)
The dio is a red sedge (Rehmannia glutinosa Liboschitz var. Purp of the Scrophulariaceae).
urea Makino or ehmannia glutinosa Liboschitz) can be used.

Regarding the plant in the present invention, one or more of the whole plant or leaves, roots, fruits, seeds and flowers of the plant can be used as it is or after being crushed.

As the extract, various solvent extracts obtained by further extracting the extract at room temperature or under heating or by using an extractor such as a Soxhlet extractor, its diluted solution, Use the concentrate or its dried powder. Here, the extract may be obtained from two or more kinds of plants.

The extraction solvent used to obtain the plant extract of the present invention may be either a polar solvent or a non-polar solvent. For example, water; methanol,
Alcohols such as ethanol, propanol and butanol; polyhydric alcohols such as propylene glycol and butylene glycol; ketones such as acetone and methyl ethyl ketone; esters such as methyl acetate and ethyl acetate; chain and cyclics such as tetrahydrofuran and diethyl ether Ethers; polyethers such as polyethylene glycol; halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride; hydrocarbons such as hexane, cyclohexane, petroleum ether; aromatic hydrocarbons such as benzene and toluene; pyridine And the like. These can be used as a mixture of two or more kinds.

The above-mentioned extract can be used as it is, but it can also be used by diluting, concentrating or freeze-drying the extract, and then preparing it in the form of powder or paste. The blending amount of the plant extract is not particularly limited, but it is suitable to set the dry weight of the plant to about 0.0001 to 10% by mass.

The composition of the present invention includes oils and fats such as vegetable oils, higher fatty acids, higher alcohols, silicones, anionic surfactants, cationic surfactants, amphoteric surfactants,
Nonionic surfactants, preservatives, sugars, sequestering agents, polymers such as water-soluble polymers, thickeners, powder components,
An ultraviolet absorber, an ultraviolet blocker, a moisturizing agent such as hyaluronic acid, a fragrance, a pH adjusting agent, a desiccant and the like can be contained. Vitamins, skin stimulants, blood circulation promoters, indigenous bacteria control agents, active oxygen scavengers, anti-inflammatory agents, anti-cancer agents,
Other medicinal and physiologically active ingredients such as a whitening agent and a bactericidal agent may be contained.

Examples of the oils and fats include camellia oil, evening primrose oil, macadamia nut oil, olive oil, rapeseed oil, corn oil, sesame oil, jojoba oil, germ oil, wheat germ oil,
Liquid oils and fats such as glycerin trioctanoate, cocoa butter,
Solid oils such as coconut oil, hardened coconut oil, palm oil, palm kernel oil, sorghum, sorghum kernel oil, hardened oil, and hardened castor oil, beeswax, candelilla wax, cotton wax, nuka wax,
Waxes such as lanolin, lanolin acetate, liquid lanolin, and sugar cane wax are mentioned.

Examples of hydrocarbons include liquid paraffin, squalene, squalane, and microcrystalline wax.

As the higher fatty acid, for example, lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid, docosahexaenoic acid (D
HA), eicosapentaenoic acid (EPA) and the like.

Examples of higher alcohols include straight chain alcohols such as lauryl alcohol, stearyl alcohol, cetyl alcohol and cetostearyl alcohol, and branched chain alcohols such as monostearyl glycerin ether, lanolin alcohol, cholesterol, phytosterols and octyldodecanol. Can be mentioned.

Examples of silicones include chain polysiloxanes such as dimethylpolysiloxane and methylphenylpolysiloxane, and cyclic polysiloxanes such as decamethylcyclopentasiloxane.

As the anionic surfactant, for example, fatty acid salt such as sodium laurate, higher alkyl sulfate ester salt such as sodium lauryl sulfate, alkyl ether sulfate ester salt such as POE lauryl sulfate triethanolamine, N-acyl sarcosinic acid, Sulfosuccinate,
Examples thereof include N-acyl amino acid salts.

Examples of the cationic surfactant include alkyltrimethylammonium salts such as stearyltrimethylammonium chloride, benzalkonium chloride and benzethonium chloride.

Examples of the amphoteric surfactant include betaine-based surfactants such as alkyl betaine and amidobetaine.

Examples of the nonionic surfactant include sorbitan fatty acid esters such as sorbitan monooleate and hydrogenated castor oil derivatives.

Examples of preservatives include methylparaben and ethylparaben.

Examples of the sequestering agent include edetate salts such as disodium ethylenediaminetetraacetate, edetic acid and sodium edetate.

Examples of the polymer include gum arabic, tragacanth gum, galactan, guar gum, carrageenan, pectin, agar, quince seed, dextran,
Examples thereof include pullulan carboxymethyl starch, collagen, casein, gelatin methyl cellulose, methyl hydroxypropyl cellulose, hydroxyethyl cellulose, sodium carboxymethyl cellulose (CMC), sodium alginate and the like.

Examples of the thickener include carrageenan, tragacanth gum, quince seed, casein, dextrin, gelatin, CMC, hydroxyethyl cellulose, hydroxypropyl cellulose, guar gum, xanthan gum and bentonite.

As the powder component, talc, kaolin, mica, silica, zeolite, polyethylene powder, polystyrene powder, cellulose powder, inorganic white pigment, inorganic red pigment, titanium oxide coated mica, titanium oxide coated talc, colored titanium oxide coated. Examples thereof include pearl pigments such as mica, and organic pigments such as Red No. 201 and Red No. 202.

Examples of ultraviolet absorbers include paraaminobenzoic acid, phenyl salicylate, isopropyl paramethoxycinnamate, octyl paramethoxycinnamate, and 2,4-dihydroxybenzophenone.

Examples of ultraviolet blocking agents include titanium oxide, talc, carmine, bentonite, kaolin, zinc oxide and the like.

As a moisturizer, polyethylene glycol,
Propylene glycol, dipropylene glycol, 1,
3-butylene glycol, 1,2-pentanediol,
Glycerin, diglycerin, polyglycerin, xylitol, maltitol, maltose, sorbitol, glucose, fructose, sodium chondroitin sulfate, sodium hyaluronate, sodium lactate, pyrrolidonecarboxylic acid, cyclodextrin and the like can be mentioned.

As the medicinal component, vitamin A oil, vitamin A such as retinol, vitamin B ₂ such as riboflavin, etc.
S, _{B 6} such as pyridoxine hydrochloride, L- ascorbic acid, L- ascorbic acid phosphoric acid ester, L- ascorbic acid monopalmitate, L- ascorbic acid dipalmitate ester, L- ascorbic acid 2-glucoside C, pantothenic acid such as calcium pantothenate, vitamin D ₂ such as vitamin D ₂ and cholecalciferol; vitamin E such as α-tocopherol, tocopherol acetate, DL-α-tocopherol nicotinate Can be mentioned.

Whitening agents such as placenta extract, glutathione and Yukinoshita extract, skin activating agents such as royal jelly and beech tree extract, capsaicin, zingerone, cantharisin tincture, ictamol, caffeine, tannic acid γ
-A blood circulation promoting agent such as oryzanol, a glycyrrhizic acid derivative, a glycyrrhetinic acid derivative, an anti-inflammatory agent such as azulene, arginine, serine, leucine, amino acids such as tryptophan, a maltose sucrose condensate of an indigenous bacterial control agent, lysozyme chloride, etc. Can be mentioned.

Furthermore, chamomile extract, parsley extract,
Beech tree extract, wine yeast extract, grapefruit extract, honeysuckle extract, rice extract, grape extract, hop extract, rice bran extract, loquat extract, yokuinin extract, assembly extract, melilot extract, birch extract, licorice extract, peony extract, soapless extract, loofah extract. Extracts, capsicum extract, lemon extract, gentian extract, perilla extract, aloe extract, rosemary extract, sage extract, thyme extract, seaweed extract, cucumber extract, carrot extract, horse chestnut extract, hamamelis extract, mulberry extract, etc. You can

The composition of the present invention is, for example, an aqueous solution, an oil solution,
The present invention can be applied in the form of liquid agents such as emulsion and kendaku, semisolid agents such as gels and creams, powders, granules, capsules, microcapsules, and solid agents such as solids. Prepared in these forms by conventionally known methods, lotions, emulsions, gels, creams, ointments, plasters, poultices, aerosols,
It can be made into various dosage forms such as suppositories, powders, granules and tablets. These can be applied to the body by applying, sticking, spraying or the like. Especially among these dosage forms, lotions, emulsions, creams, ointments, plasters, poultices,
Aerosol and the like are suitable for external preparations for skin. As cosmetics, skin cosmetics such as lotion, emulsion, cream and pack,
Make-up base lotion, make-up cream, milky or creamy or ointment-type foundation, make-up cosmetics such as lipstick, eye color, cheek color, body cosmetics such as hand cream, leg cream, body lotion, etc. Agent, oral cosmetics, and hair cosmetics.

These dosage forms can be manufactured according to the formulation method usually used in cosmetics. The sebum-regulating cosmetic composition of the present invention prevents excess skin oil from drying out and retains the function of protecting the skin from external stimuli, while suppressing excess sebum, suppressing so-called skin stickiness, and reducing shine. In particular, it is suitable for cosmetics applied to the T zone of the face where excessive secretion of sebum is a problem. Further, it is useful for preventing makeup loss and maintaining makeup.

[0042]

EXAMPLES The present invention will now be described in detail with reference to examples, but the present invention is not limited thereto. With the formulation shown in Table 1, the sebum control cosmetics of Examples 1 to 8 and Comparative Examples 1 to 7 were prepared according to a conventional method, and evaluated by the following methods. The results are shown in Table 1. [Effect of preventing shininess after use, effect of preventing makeup collapse after 2 hours of use] (Test method) Female subject in their twenties 10 who has a feeling of being in the forehead
The cosmetics of the prescription shown in Table 1 are used after washing the face,
The effect was evaluated. That is, about 0.5 g was applied to the subject's forehead, and the state of shine after 30 minutes was visually determined. Further, 0.5 g was applied to the forehead after washing the face again, and about 1.0 g of commercially available liquid foundation was applied to the forehead, and the state of makeup loss after 2 hours was visually judged.

(Criteria for judging the effect of preventing shininess) Effectiveness: a condition in which there is no shininess Effective: a condition in which there is almost no shininess: Some effect: a condition in which shininess is a little Ineffective: a condition in which shininess is present (judgment) ◎: Among subjects When there are 8 or more subjects showing marked efficacy and efficacy ○: 5 to 7 subjects showing significant efficacy and efficacy
In the case of first name Δ: 2 to 4 subjects exhibiting excellent response and efficacy
In the case of first name x: 0 to 1 of the subjects exhibiting a marked effect or efficacy
In case of first name

(Judgment Criteria for Preventing Makeup Damage) Effectiveness: No makeup damage Effectiveness: Some makeup damage is observed. Slightly effective: About half of the makeup is damaged. Ineffective: The makeup is discolored as a whole. (Judgment) ⊚: When there are 8 or more subjects showing excellent response and efficacy among the subjects ○: 5 to 7 subjects showing excellent response and efficacy among the subjects
In the case of first name Δ: 2 to 4 subjects exhibiting excellent response and efficacy
In the case of first name x: 0 to 1 of the subjects exhibiting a marked effect or efficacy
In case of first name

[Effect of reducing shine after two weeks of use] Examples 1, 2, 3 and Comparative Examples 1, 2, 5 shown in Table 1 were applied to 10 female subjects in their twenties who had a feeling of being in the forehead. , 6, 7
The cosmetic was used for 2 weeks and the effect was evaluated. That is,
The test subject's forehead was used once a day in the morning, and the condition of shine after 2 hours of face washing was evaluated by self-report. (Criteria for determining the effect of reducing shine) Effectiveness: The amount of shine was significantly reduced. Effective: Shine was moderately reduced. Slightly effective: The shine was slightly reduced. Ineffective: No change or increase in shine. (Judgment) ⊚: When there are 8 or more subjects showing excellent response and efficacy among the subjects ○: 5 to 7 subjects showing excellent response and efficacy among the subjects
In the case of first name Δ: 2 to 4 subjects exhibiting excellent response and efficacy
In the case of first name x: 0 to 1 of the subjects exhibiting a marked effect or efficacy
In case of first name

The extract of Hyougi used in this example was prepared by immersing 100 g of Hyogi in a mixed solution of ethanol, 1,3-butylene glycol and water (1: 1: 3), extracting at room temperature for 5 days and then filtering. Extract (dry solid content 0.5-
1.5% by mass), and the extract of Astragalus sinensis is 10
0 g was soaked in a mixed solution of ethanol, 1,3-butylene glycol and water (3: 3: 4) and extracted at room temperature for 5 days and night, and then filtered (dry solid content 0.5 to 1.5% by mass). ) Was used.

The sucrose extract used in this example was immersed in 100 g of sucrose pericarp in a 50% by mass ethanol solution,
After the extract was kept at 50 ° C. for 8 hours, it was filtered, and the freeze-dried part in which ethanol was distilled off by concentration under reduced pressure was dipped in 100 g of soybean soybean extract into a 50% by mass ethanol solution. After extraction, a filtered extract (dry solid content 0.3 to 1.5% by weight) was used.

[0048]

[Table 1]

The sebum control cosmetics of Examples 1 to 8 are the same as Comparative Example 1.
As compared with the cosmetics of Nos. 6 to 6, the excellent sebum-suppressing effect was obtained with less shininess after use and less cosmetic damage. And, it was possible to maintain a non-sticky state for a long time. It reduces the amount of shininess on the skin after 2 weeks of use,
A sebum suppressing effect was continuously observed.

Examples 9 to 10 will be described below. Example 9 Emulsion mass% (A) Purified water Residual 1.3-Butylene glycol 8.0 Carboxyvinyl polymer 0.12 Glycerin 3.0 Hirugi extract 0.5 Astragalus extract 0.1 (B) Jojoba oil 1. 5 Squalane 1.5 Polyoxyethylene hydrogenated castor oil 1.0 (C) Hydroxyapatite 0.1 Mica 3.0 Potassium hydroxide 0.05 [Production Method] A water phase component belonging to A and an oil phase component belonging to B are respectively Dissolve by heating, mix the oil phase component with the water phase component, and emulsify with a milking machine. After cooling, the components belonging to C were mixed and obtained.

Example 10 Beauty Serum Mass% (A) Purified Water Residual 1.3-Butylene Glycol 8.0 Trimethylglycine 2.0 Glycerin 5.0 Carboxyvinyl Polymer 0.15 Hydroxyapatite 2.0 Zinc Oxide 1.0 Sucrose extract 0.01 Soybean extract 0.1 (B) Potassium hydroxide 0.0
4 Sodium hyaluronate (1% aqueous solution) 0.1 [Production method] The components belonging to A were mixed and dissolved, and then the components belonging to B were mixed to obtain.

The milky lotion and the beauty essence obtained in Examples 9 to 10 each had a high shine-preventing effect and an excellent preventive effect on makeup makeup, and did not feel sticky over time. Furthermore, after two weeks of use, the skin had reduced shine and a sebum suppressing effect was continuously observed.

[0053]

Industrial Applicability According to the present invention, a sebum-controlling cosmetic composition containing two or more kinds of inorganic powder and plant extract can be obtained. The sebum-regulating cosmetic composition of the present invention has the effect of preventing the skin from having dryness and maintaining the function of protecting the skin from external irritation, suppressing excess sebum, suppressing so-called skin stickiness, and reducing shine. Have

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61K 7/48 A61K 7/48 F term (reference) 4C083 AA111 AA112 AB032 AB171 AB172 AB211 AB212 AB241 AB242 AB291 AB292 AB431 AB432 AB441 AB442 AC022 AC102 AC122 AC402 AC662 AD042 AD332 BB23 EE01 EE06 EE07 EE11 EE12

Claims (3)

[Claims] 1. A sebum-regulating cosmetic composition comprising two or more kinds of inorganic powder and plant extract. 2. The sebum-controlling makeup according to claim 1, wherein the inorganic powder is one or more selected from hydroxyapatite, silica, sericite, zinc oxide, titanium oxide, talc and kaolin. Fee. 3. The sebum control according to claim 1 or 2, characterized in that the plant extract is an extract of Hyogi, Astragalus radix, Saprose, Tea tree, Hawthorn, Soybean, Oat, Clove, Hawthorn and Zhio. Cosmetics.