JP2003246735A5 - - Google Patents
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- Publication number
- JP2003246735A5 JP2003246735A5 JP2002366375A JP2002366375A JP2003246735A5 JP 2003246735 A5 JP2003246735 A5 JP 2003246735A5 JP 2002366375 A JP2002366375 A JP 2002366375A JP 2002366375 A JP2002366375 A JP 2002366375A JP 2003246735 A5 JP2003246735 A5 JP 2003246735A5
- Authority
- JP
- Japan
- Prior art keywords
- active ingredient
- tetrahydrothieno
- cyclopropylcarbonyl
- fluorobenzyl
- acetoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000004480 active ingredient Substances 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 5
- 208000005189 Embolism Diseases 0.000 claims 2
- VZCYOOQTPOCHFL-UPHRSURJSA-L maleate(2-) Chemical compound [O-]C(=O)\C=C/C([O-])=O VZCYOOQTPOCHFL-UPHRSURJSA-L 0.000 claims 2
- DTGLZDAWLRGWQN-UHFFFAOYSA-N prasugrel Chemical compound C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 DTGLZDAWLRGWQN-UHFFFAOYSA-N 0.000 claims 2
- 101700019104 3SPM Proteins 0.000 claims 1
- 101700016269 3SPT Proteins 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 208000007536 Thrombosis Diseases 0.000 claims 1
- JALHGCPDPSNJNY-UHFFFAOYSA-N [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate;hydron;chloride Chemical compound Cl.C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 JALHGCPDPSNJNY-UHFFFAOYSA-N 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002366375A JP4029974B2 (ja) | 2001-12-21 | 2002-12-18 | ヒドロピリジン誘導体酸付加塩を含有する医薬 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001-388757 | 2001-12-21 | ||
| JP2001388757 | 2001-12-21 | ||
| JP2002366375A JP4029974B2 (ja) | 2001-12-21 | 2002-12-18 | ヒドロピリジン誘導体酸付加塩を含有する医薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003246735A JP2003246735A (ja) | 2003-09-02 |
| JP2003246735A5 true JP2003246735A5 (no) | 2005-06-09 |
| JP4029974B2 JP4029974B2 (ja) | 2008-01-09 |
Family
ID=28676969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002366375A Expired - Lifetime JP4029974B2 (ja) | 2001-12-21 | 2002-12-18 | ヒドロピリジン誘導体酸付加塩を含有する医薬 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4029974B2 (no) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2100608A4 (en) * | 2006-12-07 | 2009-12-09 | Daiichi Sankyo Co Ltd | METHOD FOR PRODUCING A SOLID PREPARATION |
| TWI442947B (zh) * | 2006-12-07 | 2014-07-01 | Daiichi Sankyo Co Ltd | 安定性經改善之薄膜塗覆製劑 |
| CA2672154C (en) | 2006-12-07 | 2014-11-18 | Daiichi Sankyo Company, Limited | Pharmaceutical composition having improved storage stability |
| KR101442862B1 (ko) | 2006-12-07 | 2014-09-22 | 다이이찌 산쿄 가부시키가이샤 | 만니톨 또는 유당을 함유하는 고형 제제 |
| JP5274261B2 (ja) * | 2006-12-07 | 2013-08-28 | 第一三共株式会社 | 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物 |
| MX2009009413A (es) * | 2007-03-02 | 2009-09-11 | Daiichi Sankyo Co Ltd | Metodo para la produccion de clorhidrato de prasugrel de alta pureza. |
| WO2009062044A2 (en) * | 2007-11-09 | 2009-05-14 | Dr. Reddy's Laboratories Ltd. | Processes for the preparation of prasugrel, and its salts and polymorphs |
| WO2011158931A1 (ja) * | 2010-06-17 | 2011-12-22 | 協和発酵キリン株式会社 | インダゾール誘導体の有用な塩 |
| TR201007926A1 (tr) * | 2010-07-19 | 2012-02-21 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Prasugrel tablet formülasyonları. |
| EP2409685A3 (en) * | 2010-07-19 | 2012-02-01 | Sanovel Ilac Sanayi ve Ticaret A.S. | Orally-disintegrating formulations of prasugrel |
| TR201006802A1 (tr) * | 2010-08-17 | 2012-03-21 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Prasugrelin oral yolla dağılan formülasyonları. |
| CN102775422B (zh) * | 2012-03-13 | 2014-12-31 | 山东新华制药股份有限公司 | 普拉格雷中间体的一种晶型 |
| CN104592250B (zh) * | 2015-01-15 | 2016-05-11 | 新发药业有限公司 | 一种低成本的普拉格雷的环保制备方法 |
-
2002
- 2002-12-18 JP JP2002366375A patent/JP4029974B2/ja not_active Expired - Lifetime
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