JP2003040790A - Hair tonic agent and method of producing the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To effectively utilize the waste stems and roots of Stevia and a Japanese herb, Udo (Aralia cordata), costing too much expense for their disposal as a hair tonic agent instead. SOLUTION: A mixture of Stevia and Udo is heated in a mineral water including >=50% silicic acid and >=10% of alumina to prepare a mixed concentrate whereby the antioxidative actions of Stevia and Udo are synergistically used as an anti-depilatory in a hair tonic agent.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a hair restorer used for activating hair and body hair, and a method for producing the hair restorer.

[0002]

BACKGROUND OF THE INVENTION Stevia is a plant and plant belonging to the Asteraceae family, which originates in Paraguay, South America. It has been known that stevia has sweetness and is used as a sweetness additive for foods such as pickles.

[0003] Udo is an ancient Japanese plant, and is widely used for food, but it is rarely used for medicinal purposes.

[0004]

By the way, the stevia sweetener is an extract from dried stevia leaf, and conventionally, the stem of the stevia has not been used and has been mostly discarded. In recent years, it has been clarified that the concentrated solution of stem has an antibacterial action and a detoxification action against histamine, and thus it has attracted attention.

Further, although it has been known that udo is effective for antipyretic and analgesic actions in addition to being edible, most of its stems and roots are incinerated and discarded in the field.

[0006] According to the national policy, open burning is prohibited in the future, but it is expensive to discard Stevia stems, Udo stems and roots, and it may put pressure on the management of difficult farmers. Therefore, the present invention aims to effectively utilize the stems and roots of the conventional stevia and udo, focusing on the problems in the use situation.

[0007] In the process of earnestly researching and utilizing the effective use of each of stevia and udo in accordance with this purpose, the inventors of the present invention simultaneously concentrate a mixture of stevia and udo, and the antioxidant activity of each of them is increased. We gained the knowledge that they increase synergistically. Based on this finding, the present invention intends to realize a hair-growing agent and a method for producing the same, by utilizing a material obtained by simultaneously concentrating a mixture of stevia and udo for hair growth.

[0008]

In order to solve the above-mentioned problems, the present invention provides a dry ground product of the stem of the plant plant Stevia and a dry ground product of the root of the plant plant Udo in a weight ratio of 6 to 8: 4. Two
A hair-growth agent characterized by using as a hair-growth raw material a steviaud mixed concentrated solution obtained by heating and concentrating with a mineral water having a weight ratio of 10 to 15 times to an equivalent amount of 2 to 5 times after thoroughly stirring and mixing. I will provide a.

The steviaud mixed concentrate is used as a hair-growing raw material for hair packs, soaps, hair shamps, hair lotions and the like.

5 to 30% of the above-mentioned steviaud mixed concentrate
And 95 to 70% of mineral water may be mixed to be used as a hair lotion.

The steviaud mixed concentrate is lactic acid-fermented and aged for 1 month or more to be used as a hair restorer.

In order to solve the above problems, the present invention thoroughly mixes a dry pulverized product of the stem of the plant and plant Stevia and a dry pulverized product of the root of the plant and plant Udo at a weight ratio of 6 to 8: 4 to 2. After mixing, 2 to 10 to 15 times the weight of mineral water
Provided is a method for producing a hair-growth agent, which comprises heating and concentrating to a 5-fold equivalent amount to produce a steviaud mixed concentrate which is a raw material for hair growth.

The mineral water contains 50% or more of silicic acid,
It is preferable to use water containing 10% or more of alumina.

[0014]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of a hair-growth agent and a method for producing the same according to the present invention will be described, and examples thereof will be described.

The characteristic features of the present invention are as follows. (1) The present invention utilizes the synergistic antioxidant activity of what is obtained by simultaneously concentrating a mixture of stevia and udo (hereinafter referred to as “mixed concentrate of stevia aud”) for hair loss prevention and the like. It is a thing. (2) Mineral water containing 50% of silicic acid and 10% or more of alumina is used for the mixed concentration of stevia and udo of the present invention. Hereinafter, the present invention will be described in detail along these (1) and (2).

(Regarding mixed solution of steviaudo and prevention of hair loss) Hydroxy radicals, alkoxyl radicals, superoxide anions, etc. which are active oxygen, and hydrogen peroxide and lipid peroxide, which are the sources of these, cause arteriosclerosis. It has been known that it causes various diseases and interferes with hair growth and metabolism.

Many studies have been conducted on the search for antioxidants that eliminate active oxygen from the natural world, and there are many applications to health foods. A representative example of active oxygen in such studies is the superoxide anion, which is a type of anion radical in which another electron is added to an oxygen molecule.

The relationship between such radicals and biological functions has been deeply studied, and in vivo, superoxide dismuta
The enzyme se (SOD) decomposes and detoxifies this superoxide anion, but it is known that the stronger this enzyme activity in vivo, the longer the life.

Then, the activation of the hair root is deteriorated due to the influence of active oxygen in the body such as superoxide anion and hydroxy radical, and phenomena such as hair loss and thinning hair occur. Therefore,
By eliminating the active oxygen, it is possible to prevent the hair root from degenerating and prevent hair loss and thinning hair.

On the other hand, as a result of the research and development as described above, the inventors of the present invention each obtained a product obtained by simultaneously concentrating a mixture of stevia and udo (hereinafter, referred to as "mixed concentrate of stevia aud"). It was found that the antioxidative activity possessed is synergistically increased. The antioxidant active substance in this steviaudo mixed concentrate is considered to be a polyphenol group.

Based on this finding, the present inventors applied the idea that the antioxidative activity of steviaud mixed concentrate is applied to detoxification of superoxide anion to prevent degeneration of hair roots, hair loss and thinning hair. Obtained. Furthermore, the present invention provides an active agent that eliminates active oxygen and cleans hair roots, although it causes dandruff and kayumi due to the skin degenerated due to the effect of active oxygen becoming waste products.

The present inventors have used the superoxide anion scavenging activity as an index of the antioxidant activity of the steviauud mixed concentrate. First, an enzyme called xanthine oxidase acts on a substance called xanthine to generate superoxide anion. When this anion reacts with a reagent called NBT, the solution exhibits a blue color (absorption at 560 nm). When a substance (antioxidant) that eliminates this anion is added, the blue color fades. This degree (560 nm absorption reduction degree) is measured, and the antioxidant power is evaluated as superoxide anion scavenging activity.

This activity is called SOD-like activity.
Steviado mixed concentrate has this SOD-like activity,
The concentration required to eliminate about half of the 1.7 × 10 ¹⁷ superoxide anions was 0.096 mg. This numerical value shows that the stevia aud mixed concentrate according to the present invention has an antioxidant activity of 2 to 2 as compared with stevia and udo alone.
It shows that a synergistic effect of 3 times stronger is generated.

(Use of mineral water) By the way,
If a mixture of stevia and udo is concentrated with simple tap or well water, the concentrate will spoil in a few days. In order to solve this, the present inventors have conducted extensive research and development, and have found that spoilage can be prevented when mineral water containing 50% silicic acid and 10% or more alumina is used.

Based on this finding, the method for producing a hair restorer according to the present invention is characterized in that mineral water containing 50% or more of silicic acid and 10% or more of alumina is used to concentrate a mixture of stevia and udo. It is a thing. In the present invention, tap water or well water is contacted with rocks of the Mesozoic or Paleozoic volcanic formation for 24 hours or more to obtain mineral water containing 50% silicic acid and 10% alumina.

(Regarding Hair-Growing Agent and Production Thereof) The following is a summary of the Steviado mixed concentrate according to the present invention and a method for producing the same, on the premise of the above description.

The hair restorer according to the present invention is prepared by concentrating a mixture of stevia and udo using mineral water containing 50% or more of silicic acid and 10% or more of alumina to obtain a stevia aud mixed concentrate and its antioxidant. The activity is used for hair growth including prevention of hair loss.

Then, the method for producing the hair restorer according to the present invention will be described. (1) The stem of the plant plant Stevia is dried and ground to obtain a dry powder. Similarly, the roots of the plant Udo are dried and ground to obtain a dry powder. (2) 6 to 8 dry powder of stevia and dry powder of udo:
Stir and mix well at a ratio of 4 to 2. (3) This mixed powder is put in mineral water having a weight ratio of 10 to 15 times, and heated and concentrated to an equivalent amount of 2 to 5 times to obtain a steviaud mixed concentrated solution. The mineral water used here is rock containing 50% or more silicic acid and 10% or more alumina,
Mineral water obtained by contacting tap water or well water for 24 hours or more. (4) A hair-growth agent is produced by lactic acid-fermenting a steviaud mixed concentrated solution and aging it for one month or more. (5) As a specific hair-growth product, a hair-growth lotion can be obtained by mixing 5 to 30% of steviaudo mixed concentrate with 95 to 70% of mineral water. In addition, hair packs, soaps, hair shampoos, etc. can be produced using the steviaud mixed concentrate as a raw material.

According to the hair-growth agent of the present invention thus obtained, the hair root from which the active oxygen has been eliminated is further activated by the stimulation. Specifically, the head can be cleaned by washing, the pores can be expanded with a soap or pack of Steviaudo hair-growth agent, and Stevia Audor lotion can be sprayed or applied to the hair root to eliminate active oxygen and prevent hair loss. If the hair root is stimulated by acupressure, the hair-growth effect is promoted.

(Examples) Concentrated liquid and its production: Several places of Paleozoic volcanic rock formation have been found in Japan. This time we used rocks mined from Mt. Io, Ishikawa Prefecture. 30 kg of well water,
Mineral water was prepared by forced circulation for 4 hours. The composition of the obtained mineral water is as follows.

Silicon oxide SiO ₂ 51.23% Aluminum oxide Al ₂ O ₃ 20.95% Iron oxide Fe ₂ O ₃ 4.22% Calcium oxide CaO 3.25% Sodium oxide Na ₂ O 4.27% Potassium oxide K ₂ O 12.30% Magnesium oxide MgO 0.10% Manganese oxide MnO 1.16% Titanium oxide TiO 0.36%

The present inventors have confirmed that ordinary well water rots in 2 weeks, but the mineral water according to the present invention does not rot for more than 1 year.

Stock solution for hair growth and method for producing the same: 2 kg of dry powder of Stevia stalk and 1 kg of dry powder of udo root were mixed well and stirred. Then, it was poured into 30 liters of the mineral water and concentrated at a temperature of 110 ° C. to 130 ° C. for 4 hours to obtain 8 liters of concentrated liquid. This is 15 for one month
Aging is performed in a room adjusted to a temperature of ℃, and this is used as a hair growth agent stock solution.

The main composition of the hair-growth stock solution is as follows. Vitamin A 0.03 mg Vitamin B ₂ 0.28 mg Vitamin B ₆ 0.36 mg Vitamin E 0.17 mg Niacin 3.90 mg Biotin 17.40 mg Phosphorus 200.00 mg Calcium 120.00 mg Iron 1.30 mg Sodium 22.00 mg Potassium 2200.00 mg Pantothenic acid 1.80 mg Acetic acid 3.70 mg Lactic acid 8.50 mg Yeast 0.001 mg

As an evaluation of the SOD-like activity of the above hair growth stock solution, the above superoxide anion scavenging activity (SOD
IC50 (concentration showing 50% inhibition)
As compared. As a result, SOD of steviaud concentrate
-Like activity was 0.096 mg, which was 7 times that of green tea.

Production of hair-growth products: Hair-growth lotions, hair-growth hair packs, and hair-growth soaps were produced using the above-mentioned stock solution of hair-growth agent (concentrated solution of steviaudo), which will be described below.

(1) Hair Growth Lotion A hair growth lotion was prepared by diluting the above mineral water 5 times. When diluted with ordinary tap water, it rotted in 1 week, but the hair-growth lotion produced with mineral water showed no change for 3 months even in an oxidizing atmosphere.

(2) Hair-Growing Hair Pack A hair pack containing 2% of the above stock solution of hair-growth agent was produced. 2% of hair growth concentrate was added to the specifications of the cosmetics manufacturing application guidebook supervised by the Pharmaceutical Affairs Bureau of the Ministry of Health and Welfare.

(3) Hair-Growing Soap A soap containing 2% of the steviaud concentrate was prepared. 2% of hair growth concentrate was added to the specifications of the cosmetics manufacturing application guidebook supervised by the Pharmaceutical Affairs Bureau of the Ministry of Health and Welfare.

Evaluation Experiment: An evaluation experiment was conducted to confirm the effect of the hair-growth agent of the present invention. In the evaluation experiment, in order to ensure the objectivity of the evaluation, a certain usage pattern was defined as follows. Usage 1 The head is washed thoroughly with ordinary shampoo or soap. After washing, rub the above hair growth hair pack, dry and wash again. After washing away the hair-growth hair pack, the head is pressed from the bottom to the top while spraying the hair-growth lotion 5 to 6 times. Usage Mode 2 The head is thoroughly washed with the above hair-growth soap. After washing, the head is pressed from the bottom to the top while spraying a hair growth lotion 5 to 6 times.

The results of the evaluation experiments in the above-mentioned usage modes 1 and 2 are as follows. (1) Experimental Example Performed in Use Mode 1 An experiment was carried out in a male in his thirties with a bald top of the head. Hair grew on the bald area of about 40% in 3 weeks. The experiment was conducted in a man in his 40s with a bald head. Hair grew on the bald area of about 50% in 2 weeks. The experiment was conducted in a man in his 50s with a bald head. Hair grew in about 30% of the bald areas in 4 weeks. The experiment was conducted in a woman in her 40s with a bald top of her head. Hair grew in about 30% of the bald areas in 4 weeks. I experimented with a woman in her 50s with a bald upper part of her forehead. After 4 weeks, hair regrowth started and the hair gradually became thicker and blacker.

(2) Example of Experiment Performed in Use Mode 2 An experiment was conducted in a man in his 40s with a bald upper part of the forehead. After 4 weeks, hair regrowth started and the hair gradually became thicker and blacker. I experimented with a man in his 50s with a bald upper part of his forehead. After 5 weeks, hair regrowth started and the hair gradually became thicker and blacker. I experimented with a woman in her 40s with a bald upper part of her forehead. Hair regrowth occurred within 3 weeks and the hair gradually became thicker and blacker. The experiment was conducted in a woman in her 40s with a bald top of her head. After 4 weeks, hair regrowth started and the hair gradually became thicker and blacker. The experiment was conducted in a woman in her fifties with a bald head. After 5 weeks, hair regrowth started and the hair gradually became thicker and blacker.

Although the embodiments of the hair-growing agent and the method for producing the same according to the present invention have been described above with reference to the examples, the present invention is not particularly limited to such embodiments and examples. It goes without saying that there are various embodiments and examples within the scope of the technical matters described in the range.

[0044]

EFFECTS OF THE INVENTION Since the hair restorer and the method for producing the same according to the present invention are configured as described above, the following effects are exhibited. (1) The stems and roots of Stevia and Udo, which had been forced to be disposed of conventionally, can be effectively utilized, which is not only a source of income but also the cost required for disposal can be reduced and the economical effect is extremely large.

(2) The stevia-udd concentrated mixture obtained by simultaneously concentrating the mixture of stevia and udo synergistically enhances the antioxidative activity of each, and the use of mineral water also synergistically prevents spoilage. Since it is added in a natural manner, it is possible to exert the effects of hair loss prevention, hair growth effect, and dandruff occurrence prevention at low cost with a naturally derived material.

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61P 17/14 A61P 17/14 F term (reference) 4C083 AA032 AA111 AA112 AB171 AB172 AB212 AB221 AB222 AB232 AB242 AC232 AC302 AC642 AC852 AC862 AD622 AD632 AD662 CC33 CC37 CC38 DD21 DD23 4C088 AB17 AB26 AC05 AC11 CA28 MA07 MA17 MA34 MA63 NA14 ZA92 ZC75

Claims (7)

[Claims] 1. A dry ground product of the stem of the plant plant Stevia and a dry ground product of the root of the plant plant Udo are used in a weight ratio of 6 to 8: 4.
It is characterized in that a steviaud mixed concentrate obtained by stirring and mixing well at a ratio of 2 to 2 and then heating and concentrating it in mineral water at a weight ratio of 10 to 15 to an equivalent amount of 2 to 5 is used as a hair-growing material. Hair restorer. 2. The hair restorer according to claim 1, wherein the steviaudo mixed concentrate is used as a hair restorer for a hair pack, soap, hair shampoo or hair lotion. 3. The steviaud mixed concentrate as 5 to 3
The hair restorer according to claim 1 or 2, which is used as a hair lotion by mixing 0% and 95 to 70% of mineral water. 4. The hair-growing agent according to claim 1, which is obtained by lactic acid-fermenting the steviaud-mixed concentrated solution and aging it for 1 month or more. 5. The hair restorer according to claim 1, wherein the mineral water is water containing 50% or more of silicic acid and 10% or more of alumina. 6. A dry ground product of the stem of the plant plant Stevia and a dry ground product of the root of the plant plant Udo are contained in a weight ratio of 6 to 8: 4.
After stirring and mixing well at a ratio of ~ 2, the mixture is heated and concentrated to a ratio of 2 to 5 times with mineral water having a weight ratio of 10 to 15 to produce a steviaud mixed concentrate which is a raw material for hair growth. Method of manufacturing agent. 7. The method for producing a hair restorer according to claim 6, wherein the mineral water is water containing 50% or more of silicic acid and 10% or more of alumina.