JP2003027083A - Lubricant for condom and condom - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an aqueous lubricant for a condom containing a polyphenol and to provide a condom coated with the aqueous lubricant, where the aqueous lubricant has an inhibiting effect on viruses, and at the same time, can avoid an underwear from getting dirty even when the aqueous lubricant is adhered to it. SOLUTION: This lubricant for condom is an aqueous lubricant containing a tea polyphenol, and has a virus inhibiting function due to an appropriate amount of the tea polyphenol in the aqueous lubricant, and coloring of an underwear when the lubricant adheres to it is avoided by setting the caffeine content in the tea polyphenol within a definite range.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an aqueous lubricant for condoms and a condom coated with this aqueous lubricant. More specifically, it is an aqueous condom aqueous solution for controlling viruses such as AIDS and Condyloma acuminata. The present invention relates to a lubricant and a condom coated with the water-based lubricant.

[0002]

2. Description of the Related Art Conventionally, silicone oil has been widely used as a lubricant for condoms, but some users find silicone oil unnatural in terms of sliminess and wettability because it is oily. Further, when the lubricant made of silicone oil adheres to the body or underwear, it is difficult to wash it off. In view of the above-mentioned circumstances, the applicant of the present invention has developed an aqueous lubricant for condoms and a condom coated with this aqueous lubricant (Japanese Patent Laid-Open No. 10-298060). This water-based lubricant is a solution of glycerin in a sodium lactate solution (penetrating agent)
Among propylene glycols (wetting agents), an aqueous solution obtained by mixing one or two kinds is used as a main ingredient, and pullulan (a slimming agent) is added thereto. An appropriate amount of the above-mentioned water-based lubricant is dripped into the rolled-up condom to be infiltrated into the package.

The above-mentioned water-based lubricant has a good penetrability, and when it is dropped on a rolled-up condom, it can be penetrated deeply into the condom winding part. Further, this water-based lubricant has an advantage that it can prevent whitening of the condom due to water absorption. When applied to a condom, the above-mentioned water-based humectant gives a moist feel, and also reduces the discomfort during use due to the slimy feeling close to body fluid, forming a condom with a pleasant feel. Further, since the above-mentioned water-based lubricant is water-soluble even when it adheres to the body or underwear, it can be washed off relatively easily and is very convenient to use.

[0004]

By the way, recently,
Virus infections such as AIDS and Condyloma acuminata have become a social problem. It is known as one of the effective preventive measures to use a condom as a contraceptive against these viral infections. On the other hand, it has been proposed to more effectively prevent the above-mentioned virus infection by using a jelly solution in which a virus inhibitor such as tannin is mixed with an aqueous lubricant to be applied to a condom (JP-A-6-
189997, JP-A-6-189998). The above-mentioned water-based lubricant has a virus-inhibiting effect by applying tannin or the like to the surface of the condom. However, since it contains tea polyphenol (tannin) extracted from plants, it is a water-soluble lubricant. Even if it is an agent, there is a problem that it will stain and stain if it adheres to underwear,
It could not be washed off easily.

An object of the present invention is to provide an aqueous condom lubricant containing tea polyphenol (tannin) extracted from a plant, and a condom coated with this aqueous lubricant.
The purpose is to provide the above-mentioned water-based lubricant with a virus suppressing effect.

[0006]

In order to solve the above-mentioned problems, the water-based lubricant for condoms of the present invention is a water-based lubricant containing tea polyphenol and is used by applying it to both inner and outer surfaces of a condom. The tea polyphenol contained in the above-mentioned water-based lubricant is the inner and outer surfaces of the condom,
That is, the male or female side suppresses the virus and suppresses the virus infection from the carrier.
Further, tea polyphenol has a bactericidal effect against various bacteria in addition to viruses, and can prevent deodorization due to sterilization. The water-based lubricant for condoms according to claims 2 to 5 and the condom coated with this water-based lubricant will be described together in the section of the embodiment of the invention.

In the present invention, the tea polyphenol means tea (Camellia sinensis O).
Kuntze (Thea sinensis L.))
A polyphenol contained in leaves and stems.

The polyphenol in the present invention means a group of substances having two or more hydroxyl groups on the same benzene ring, and generally has the same structure as resorcinol, catechol, hydroquinone, pyrogallol, phloroglucinol and their compounds. Examples thereof include compounds having

There are various kinds of polyphenol compounds in tea, and most of them are polyoxy derivatives of flavan-3-ol (Flavan-3-ol) represented by the following general formula (I) or related compounds thereof. Exist as flavan-3-ols.

[0010]

[Chemical 1]

Typical flavan-3-ols contained in tea are, for example, THEHANDBOOK.
OF NATURAL FLAVONOIDS (Vo
lume1, 2) Copyright 1999 by
Listed in JOHN WILEY & SONS, LTD. As the tea polyphenol in the present invention, the above flavan-3-ols are preferable, and among them, the compound represented by the following general formula (II) is most preferable.

[0012]

[Chemical 2]

In the formula (II), R1, R2 and R3 each represent a hydrogen atom or a hydroxyl group, and R4 represents a hydrogen atom or a galloyl group represented by the following general formula (III). )

[0014]

[Chemical 3]

The compound represented by the above general formula (II) has asymmetric carbon atoms at the 2- and 3-positions of the benzopyran ring. In the present invention, the isomers derived from these asymmetric carbon atoms are not limited. Absent.

Specific examples of the compound represented by the above general formula (II) include (-)-epicatechin ((-)
-Epicatechin: R1 and R in formula (II)
2 represents a hydroxyl group, R3 and R4 represent hydrogen atoms, and the configurations at the 2-position and 3-position represent 2R and 3R. ), (-)
-Catechin ((-)-catechin: In the formula (II), R1 and R2 each represent a hydroxyl group, R3 and R4 each represent a hydrogen atom, and the configurations at the 2- and 3-positions represent 2S and 3R), (+ ) -Catechin ((+)-catechi
n: In the formula (II), R1 and R2 represent a hydroxyl group, and R
3, R4 represents a hydrogen atom, and the configurations at the 2- and 3-positions represent 2R and 3S. ), (+)-Epicatechin ((+)-epicatechin: In the formula (II), R1 and R2 represent a hydroxyl group, R3 and R4 represent a hydrogen atom, and the configurations at the 2- and 3-positions are 2S and 3S. ), (−)-Epicatechin gallate ((−)-ep
icatechinglate: In the formula (II), R1 and R2 represent a hydroxyl group, R3 represents a hydrogen atom, and R
4 represents a galloyl group, and the configurations of 2- and 3-positions are 2
Represents R and 3R. ), (-)-Catechin gallate ((-)-catechin gallate: formula (I
In I), R1 and R2 represent a hydroxyl group, R3 represents a hydrogen atom, R4 represents a galloyl group, and the configurations at the 2- and 3-positions represent 2S and 3R. ), (+)-Catechin gallate:
In the formula (II), R1 and R2 represent a hydroxyl group, R3 represents a hydrogen atom, R4 represents a galloyl group, and 2-position and 3-position
The configuration of position represents 2R, 3S. ), (+)-Epicatechin gallate ((+)-epicateching
allate: In the formula (II), R1 and R2 represent a hydroxyl group, R3 represents a hydrogen atom, R4 represents a galloyl group, and the configurations at the 2- and 3-positions represent 2S and 3S. ), (−)-Epigallocatechin ((−)-epig
allocatechin: R1 and R in formula (II)
2, R3 represents a hydroxyl group, R4 represents a hydrogen atom, and the configurations at the 2- and 3-positions represent 2R and 3R. ), (-)
-Gallocatechin ((-)-gallocatechi
n: In the formula (II), R1, R2, and R3 each represent a hydroxyl group, R4 represents a hydrogen atom, and the configurations at the 2- and 3-positions represent 2S and 3R. ), (+)-Gallocatechin ((+)-gallocatechin: In formula (II), R1, R2, and R3 represent a hydroxyl group, R4 represents a hydrogen atom, and the configurations at the 2- and 3-positions represent 2R and 3S. .), (+)-Epigallocatechin ((+)-epig.
allocatechin: R1 and R in formula (II)
2, R3 represents a hydroxyl group, R4 represents a hydrogen atom, and the configurations at the 2- and 3-positions represent 2S and 3S. ), (-)
-Epigallocatechin gallate ((-)-epigal)
Octachin gallate: In the formula (II), R1, R2, and R3 represent a hydroxyl group, R4 represents a galloyl group, and the configurations at the 2- and 3-positions represent 2R and 3R. ), (-)-Gallocatechin gallate ((-)-ga
Llocatechin gallate: In the formula (II), R1, R2, and R3 represent a hydroxyl group, R4 represents a galloyl group, and the configurations at the 2- and 3-positions represent 2S and 3R. ), (+)-Gallocatechin gallate ((+)-g
allocatechin gallery: Formula (II)
In, R1, R2, and R3 represent a hydroxyl group, R4 represents a galloyl group, and the configurations at the 2- and 3-positions are 2R and 3S.
Represents ), (+)-Epigallocatechin gallate ((+)-epigallocatechin gal
late: In the formula (II), R1, R2, and R3 represent a hydroxyl group, R4 represents a galloyl group, and the configurations at the 2- and 3-positions represent 2S and 3S. ), (-)-Epiafzelechin ((-)-epiafzelechin: Formula (II)
In, R1, R3, and R4 represent a hydrogen atom, R2 represents a hydroxyl group, and the configurations at the 2- and 3-positions represent 2R and 3R. ), (-)-Afzelequin ((-)-afzel
echin: In the formula (II), R1, R3, and R4 represent hydrogen atoms, R2 represents a hydroxyl group, and the configurations at the 2- and 3-positions represent 2S and 3R. ), (+)-Afzelechin ((+)-afzelechin: R in formula (II)
1, R3 and R4 each represent a hydrogen atom, R2 represents a hydroxyl group, and the configurations at the 2- and 3-positions represent 2R and 3S. ), (+)-Epiafzerekin ((+)-epia
fzelechin: R1, R3, R in formula (II)
4 represents a hydrogen atom, R2 represents a hydroxyl group, and the configurations at the 2- and 3-positions represent 2S and 3S. ), (-)-Epiafzelequingallate ((-)-epiafzelec
Hinglate: In the formula (II), R1 and R3 are hydrogen atoms, R2 is a hydroxyl group, R4 is a galloyl group, and the configurations at the 2- and 3-positions are 2R and 3R. ), (-)-Afzelequin gallate ((-)-af
zelechinglate: R in formula (II)
1, R3 is a hydrogen atom, R2 is a hydroxyl group, R4 is a galloyl group, and the configurations at the 2- and 3-positions are 2S and 3R.
Represents ), (+)-Afzelequin gallate ((+)-
afzelechinglate: In the formula (II), R1 and R3 are hydrogen atoms, R2 is a hydroxyl group, R4 is a galloyl group, and the configurations at the 2- and 3-positions are 2R,
Represents 3S. ), (+)-Epiafzelequingallate ((+)-epiafzelechingingallat)
e: In the formula (II), R1 and R3 are hydrogen atoms, R2 is a hydroxyl group, R4 is a galloyl group, and the configurations at the 2- and 3-positions are 2S and 3S. )and so on.

In the present invention, tea leaves, stems, xylem, bark, roots, fruits and seeds, or processed products thereof can be appropriately selected and used as the raw material for the polyphenol compound. Examples of the processed product include green tea, oolong tea, and black tea obtained by processing tea leaves and stems for drinking. These raw materials can be used as they are in the present invention by adjusting the particle size to an appropriate size, but usually, the polyphenol compound is further extracted from these raw materials with water, hot water, a water-containing organic solvent and an organic solvent. To use. The final form of the extract used in the present invention may be liquid or solid (including powder). In the present invention, not only these extracts, but also polyphenol compounds purified from these extracts to a desired purity can be used.

As a method for obtaining a polyphenol compound from tea, for example, Japanese Patent Publication No. 1-44232 and 2-1.
No. 2474, No. 2-22755, and Japanese Unexamined Patent Publication (Kokai) No. 4-
No. 20589, No. 5-260907, No. 8-
Specific examples are described in Japanese Patent No. 109178 and the like.

[0019]

BEST MODE FOR CARRYING OUT THE INVENTION An embodiment of the present invention will be described below with reference to the drawings. As shown in FIG. 1, a condom a
Forms a semen reservoir 2 at the tip of the condom body 1,
Moreover, a mouthpiece 3 is formed on the opening edge of the condom body 1 on the base end side. The condom a shown in FIGS. 2 to 4 shows a state in which the mouthpiece 3 is raised to be housed in the package b. The condom a wound with the roll 3 is placed on the sheet b1 constituting one side of the package b (FIG. 3), and a predetermined amount of the water-based lubricant c is dropped immediately before covering the other sheet b2. . After that, the sheet b2 is superposed on the sheet b1 on which the condom a is placed as described above, and the four sides of the sheet b2 are thermocompression-bonded to be housed in the package b in a sealed state (FIG. 4).

As described above, in the condom a to which the water-based lubricant c has been dropped, the water-based lubricant c penetrates into the rolled-in portion in the state of being housed in the package, whereby the water-based lubricant c is evenly applied to both the inner and outer surfaces. It will be in the state (FIG. 3, FIG. 4).

The water-based lubricant c applied to the condom a as described above is composed of the following components.・ Trimethylglycine (glycine derivative) ・ ・ ・ 200-450g ・ Glycerin ・ ・ ・ 100-200g ・ Water ・ ・ ・ 300-700g ・ Pullulan (natural polysaccharide) ・ ・ ・ ・ ・ 5-40g -Tea polyphenol: 0.01 to 1 g In this example, (tea polyphenon 70S manufactured by Tokyo Food Techno Co., Ltd.) was used as tea phenol.
The amount of the water-based lubricant compounded as described above is preferably in the range of 50 mg to 800 mg per condom.

The polyphenon 70 used in the present invention is described below.
The composition of S is shown.

[Table 1]

Aqueous lubricant c blended in the above proportion
By properly mixing trimethylglycine (glycine derivative), glycerin, water, and pullulan, it has appropriate sliminess and moisturizing feeling, and becomes close to body fluid.

The above-mentioned water-based lubricant c will not be whitened by being absorbed by the condom a. Also, since the same water-based lubricant has excellent penetrability, when it is dropped on a rolled up condom, it quickly penetrates into the inside of the rolled up part,
When stored in the package, it will spread evenly on both the inside and outside of the condom.

The tea polyphenol contained in the aqueous lubricant has a function of suppressing viruses such as Condyloma acuminata and AIDS, and therefore can prevent viral infection due to sexual intercourse. Further, tea polyphenol has a bactericidal effect against various bacteria in addition to viruses, and also has a deodorizing effect by sterilization.

As described above, by using the tea polyphenol added to the water-based lubricant c in a necessary minimum amount of 0.001% to 0.5% by weight, a good bactericidal effect can be obtained and an aqueous solution containing the tea polyphenol can be obtained. Even if the lubricant c adheres to underwear or the like, it is not colored because the addition amount is suppressed, and even if it is colored, it can be easily washed off. Further, since pullulan is added as a natural polysaccharide, the strong astringency of tannin contained in tea polyphenol can be alleviated by the sweetness of the pullulan. Therefore, even when the water-based lubricant enters the mouth, the astringent taste of tannin does not cause an unpleasant feeling.

[0027]

EFFECTS OF THE INVENTION The water-based lubricant for condoms of the present invention is a water-based water-based lubricant for condoms containing tea polyphenol. On the inner and outer surfaces of the condom, that is, on the male side or the female side, viruses such as AIDS and Condyloma acuminata can be suppressed, and viral infection from carriers can be prevented by sexual intercourse. Further, tea polyphenol has a bactericidal effect against various bacteria in addition to viruses, and also has a deodorizing effect by sterilization.

In the aqueous lubricant for a condom according to claim 2, at least one of a glycine derivative and a saccharide is added to an aqueous lubricant containing tea polyphenol, and the addition amount is 20% by weight in the aqueous lubricant. %, The glycine derivative can produce an appropriate slimy feel and a moist feel. Further, since the water-based lubricant is improved in the penetrability, when it is dropped on the rolled-up condom, it penetrates both inside and outside of the condom and is coated on the entire surface. Furthermore, in the glycine derivative, the condom absorbs the water content of the water-based lubricant and becomes white,
It is possible to prevent problems that the physical properties are deteriorated. Also, by adding an appropriate amount of sugar, the astringency of tea polyphenol can be canceled by the sweetness of the glycine derivative.
Therefore, even if the above-mentioned water-based lubricant gets into the mouth due to any result, the astringency of tannin does not cause any unpleasant feeling.

The water-based lubricant for a condom according to claim 3 is the water-based lubricant for a condom according to claim 2,
Since trimethylglycine is used as a glycine derivative and 20% by weight of this is contained in an aqueous lubricant containing tea polyphenol, the sweetness of trimethylglycine naturally suppresses the astringency of tea polyphenol (tannin). , Can effectively relieve unpleasant taste.

Since the condom according to claim 4 is formed by applying the water-based lubricant for a condom according to any one of claims 1 to 4, the effect of the above-mentioned water-based lubricant during use, that is, It has the effect of suppressing viruses, natural sliminess, sterilization, deodorization and moisturizing effects.

The condom according to claim 5 is an aqueous condom-containing aqueous lubricant for a tea condom, wherein caffeine is added in an amount of 0.625% by weight or less to 100% by weight of the tea polyphenol. The tea polyphenol in the lubricant was made 0.001 to 0.5% by weight, and 50 mg to 800 mg of this aqueous lubricant was applied. Therefore, it is excellent in suppressing viruses contained in tea polyphenol. Further, by setting caffeine at 0.625% by weight or less, even when the water-based lubricant adheres to underwear or the like, it is not colored, and even if it is colored, it can be easily washed off.

[Brief description of drawings]

FIG. 1 is a front view showing a condom of the present invention.

FIG. 2 is a perspective view showing the condom in a rolled-up state.

FIG. 3 is a vertical sectional view showing the condom in a rolled-up state.

FIG. 4 is a sub-sectional view showing the condom stored in a package.

[Explanation of symbols]

a ... condom b ... Package c ... Water-based lubricant 1 ... Condom body 2 semen reservoir 3 ...

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61K 31/522 A61K 35/78 C 4H104 35/78 47/18 47/18 47/22 47/22 A61P 31 / 12 A61P 31/12 31/18 31/18 C10M 129/20 C10M 129/20 129/24 129/24 133/06 133/06 145/40 145/40 159/02 159/02 C10N 30:16 // C10N 30:16 40:00 Z 40:00 A61F 5/43 (72) Inventor Masahiko Hara, 1-26, Kanda Sakumacho, Chiyoda-ku, Tokyo Tokyo Food Techno Co., Ltd. F-term (reference) 4C076 AA12 BB31 CC35 DD19 DD51 EE30 FF11 4C086 AA01 AA02 BA08 MA01 MA02 MA04 MA05 MA63 NA08 ZB33 ZC55 4C088 AB45 BA32 CA03 MA02 MA04 MA17 MA63 NA08 ZB33 ZC55 4C098 AA06 EE11 4C206 AA01 AA02 A01 AA02 CA19 MA01 MA02 MA04 MA05 A10 A02 A08 A33 A08 0 QA01

Claims (5)

[Claims] 1. A water-based condom lubricant containing tea polyphenols. 2. A lubricant for a condom, comprising at least one of a glycine derivative and a saccharide added to an aqueous lubricant containing tea polyphenol, and the addition amount of 20% by weight or more of the aqueous lubricant. 3. The lubricant for a condom according to claim 2, wherein the glycine derivative is trimethylglycine, and 20% by weight or more of the glycine derivative is contained in an aqueous lubricant containing tea polyphenol. 4. A condom formed by applying the condom lubricant according to claim 1. 5. A water-based condom lubricant containing tea polyphenol, comprising 100 parts of the tea polyphenol.
The amount of caffeine added is controlled to 0.625% by weight or less, and the tea polyphenol content in the aqueous lubricant is set to 0.001 to 0.5% by weight based on the weight%.
Condom made by applying mg to 800 mg.