AU2001278804A1 - 5'-deoxy-n-(substituted oxycarbonyl)-5-fluorocytosine and derivatives thereof, method of preparing same, and anticancer composition comprising same as active ingredients - Google Patents

5'-deoxy-n-(substituted oxycarbonyl)-5-fluorocytosine and derivatives thereof, method of preparing same, and anticancer composition comprising same as active ingredients

Info

Publication number
AU2001278804A1
AU2001278804A1 AU2001278804A AU7880401A AU2001278804A1 AU 2001278804 A1 AU2001278804 A1 AU 2001278804A1 AU 2001278804 A AU2001278804 A AU 2001278804A AU 7880401 A AU7880401 A AU 7880401A AU 2001278804 A1 AU2001278804 A1 AU 2001278804A1
Authority
AU
Australia
Prior art keywords
same
fluorocytosine
deoxy
derivatives
active ingredients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001278804A
Inventor
Sung-Min Cho
Ji-Young Kim
Kwan-Hee Kim
Youn-Chul Kim
Kyeongho Lee
Moon-Jong Noh
Ho-Jin Park
Young-Seok Park
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kolon Industries Inc
Original Assignee
Kolon Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020000046179A external-priority patent/KR100730768B1/en
Priority claimed from KR1020010044193A external-priority patent/KR20030009649A/en
Application filed by Kolon Industries Inc filed Critical Kolon Industries Inc
Publication of AU2001278804A1 publication Critical patent/AU2001278804A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU2001278804A 2000-08-09 2001-08-08 5'-deoxy-n-(substituted oxycarbonyl)-5-fluorocytosine and derivatives thereof, method of preparing same, and anticancer composition comprising same as active ingredients Abandoned AU2001278804A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR1020000046179A KR100730768B1 (en) 2000-08-09 2000-08-09 5'-deoxy-N-alkyloxycarbonyl-5-fluorocytosine-5'-carboxylic acid and its derivatives, and process for preparing thereof
KR0046179 2000-08-09
KR1020010044193A KR20030009649A (en) 2001-07-23 2001-07-23 N-alkynyloxycarbonyl-5-fluorocytosine derivatives, their preparation method, and anticancer agent comprising the same
KR0144193 2001-07-23
PCT/KR2001/001351 WO2002011668A2 (en) 2000-08-09 2001-08-08 5'-deoxy-n-(substituted oxycarbonyl)-5-fluorocytosine and derivatives thereof, method of preparing same, and anticancer composition comprising same as active ingredients

Publications (1)

Publication Number Publication Date
AU2001278804A1 true AU2001278804A1 (en) 2002-02-18

Family

ID=26638291

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001278804A Abandoned AU2001278804A1 (en) 2000-08-09 2001-08-08 5'-deoxy-n-(substituted oxycarbonyl)-5-fluorocytosine and derivatives thereof, method of preparing same, and anticancer composition comprising same as active ingredients

Country Status (5)

Country Link
EP (1) EP1311524A2 (en)
JP (1) JP2004505899A (en)
CN (1) CN1446225A (en)
AU (1) AU2001278804A1 (en)
WO (1) WO2002011668A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2045256A4 (en) * 2006-07-21 2009-09-02 Taiho Pharmaceutical Co Ltd 2'-cyanopyrimidine nucleoside compound
CN101993464B (en) * 2009-08-19 2014-07-23 成都弘达药业有限公司 Preparation method of capecitabine
CN103897004B (en) * 2012-12-27 2017-05-31 鲁南制药集团股份有限公司 A kind of synthetic method of capecitabine
WO2018002739A1 (en) * 2016-06-28 2018-01-04 Cellix Bio Private Limited Compositions and methods for the treatment of cancer
JP7173613B2 (en) * 2017-04-26 2022-11-16 カールマン，トーマス，アイ． Multi-targeted nucleoside derivatives
SG11202100411TA (en) * 2018-08-03 2021-02-25 Cellix Bio Private Ltd Compositions and methods for the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968914A (en) * 1987-10-28 1999-10-19 Pro-Neuron, Inc. Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
US6642245B1 (en) * 1990-02-01 2003-11-04 Emory University Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane

Also Published As

Publication number Publication date
CN1446225A (en) 2003-10-01
WO2002011668A3 (en) 2002-04-18
JP2004505899A (en) 2004-02-26
EP1311524A2 (en) 2003-05-21
WO2002011668A2 (en) 2002-02-14

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