JP2002542820A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002542820A5 JP2002542820A5 JP2000615743A JP2000615743A JP2002542820A5 JP 2002542820 A5 JP2002542820 A5 JP 2002542820A5 JP 2000615743 A JP2000615743 A JP 2000615743A JP 2000615743 A JP2000615743 A JP 2000615743A JP 2002542820 A5 JP2002542820 A5 JP 2002542820A5
- Authority
- JP
- Japan
- Prior art keywords
- psa
- antibody
- sample
- lys145
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 18
- 238000003776 cleavage reaction Methods 0.000 claims 15
- 230000007017 scission Effects 0.000 claims 15
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 239000012634 fragment Substances 0.000 claims 10
- 210000001519 tissue Anatomy 0.000 claims 4
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 3
- 239000004472 Lysine Substances 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 208000004403 Prostatic Hyperplasia Diseases 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 238000004128 high performance liquid chromatography Methods 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 210000000582 semen Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/303,208 US6482599B1 (en) | 1999-04-30 | 1999-04-30 | Forms of prostate specific antigen (PSA) specific for benign prostatic hyperplasia (BPH) and methods of using such |
| US09/303,208 | 1999-04-30 | ||
| PCT/US2000/009415 WO2000066718A1 (en) | 1999-04-30 | 2000-04-07 | Forms of prostate specific antigen (psa) specific for benign prostatic hyperplasia (bph) and methods of using such |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002542820A JP2002542820A (ja) | 2002-12-17 |
| JP2002542820A5 true JP2002542820A5 (enExample) | 2007-06-14 |
Family
ID=23171019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000615743A Pending JP2002542820A (ja) | 1999-04-30 | 2000-04-07 | 良性前立腺過形成に特異的な型の前立腺特異抗原（ｐｓａ）とその利用法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6482599B1 (enExample) |
| EP (1) | EP1173556A1 (enExample) |
| JP (1) | JP2002542820A (enExample) |
| AU (1) | AU780458B2 (enExample) |
| CA (1) | CA2371577A1 (enExample) |
| WO (1) | WO2000066718A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2807438B1 (fr) * | 2000-04-10 | 2004-09-17 | Bio Merieux | Nouveaux anticorps reconnaissant specifiquement le psa libre inactif, et leurs applications |
| FI20002127A0 (fi) * | 2000-09-27 | 2000-09-27 | Artic Partners Oy Ab | Uusi vasta-aine, immunomääritys ja menetelmä eturauhassyövän havaitsemiseksi |
| US20050037447A1 (en) * | 2003-07-08 | 2005-02-17 | Yong-Chuan Wong | Protein markers for human benign prostatic hyperplasia (BPH) |
| CA2593184A1 (en) * | 2005-01-06 | 2006-07-13 | Eastern Virginia Medical School | Apolipoprotein a-ii isoform as a biomarker for prostate cancer |
| EP1864134A4 (en) * | 2005-02-07 | 2010-10-20 | Univ Columbia | METHOD FOR TREATING OR PREVENTING HORMONRESISTENT PROSTATE CANCER USING PROTOCADHERINE PC SPECIFIC SIRNA OR OTHER INHIBITORS OF PROTOCADHERINE PC EXPRESSION OR ACTIVITY |
| US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
| US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
| US8968210B2 (en) | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
| US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
| US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
| CA2853705C (en) * | 2011-10-25 | 2021-10-12 | Memorial Sloan-Kettering Cancer Center | Free psa antibodies as diagnostics, prognostics and therapeutics for prostate cancer |
| US11433260B2 (en) | 2015-12-21 | 2022-09-06 | Gholam A. Peyman | Cancer treatment methods using thermotherapy and/or enhanced immunotherapy |
| US10136820B2 (en) * | 2015-12-21 | 2018-11-27 | Gholam A. Peyman | Method to visualize very early stage neoplasm or other lesions |
| AU2019301756A1 (en) * | 2018-07-12 | 2021-01-28 | Berg Llc | Methods for differentiating benign prostatic hyperplasia from prostate cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998010292A1 (en) * | 1996-09-06 | 1998-03-12 | Centocor, Inc. | Monoclonal antibodies specific for prostate specific antigen and methods of detecting prostate specific antigen |
| US5858685A (en) | 1997-03-21 | 1999-01-12 | The Board Of Trustees Of The Leland Stanford Junior University | Prostate specific antigen from benign prostatic hyperplasia and its use in diagnosis |
-
1999
- 1999-04-30 US US09/303,208 patent/US6482599B1/en not_active Expired - Lifetime
-
2000
- 2000-04-07 JP JP2000615743A patent/JP2002542820A/ja active Pending
- 2000-04-07 AU AU42187/00A patent/AU780458B2/en not_active Expired
- 2000-04-07 WO PCT/US2000/009415 patent/WO2000066718A1/en not_active Ceased
- 2000-04-07 CA CA002371577A patent/CA2371577A1/en not_active Abandoned
- 2000-04-07 EP EP00921930A patent/EP1173556A1/en not_active Withdrawn
-
2002
- 2002-09-24 US US10/252,862 patent/US20030119033A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0540573B1 (en) | Assay of free and complexed prostate-specific antigen (psa) | |
| JP4274330B2 (ja) | ｃＰＳＡの測定方法 | |
| ES2238678T3 (es) | Inmunodosificados relativos al antigeno especifico de la prostata. | |
| Liu et al. | Analysis of serum total and free PSA using immunoaffinity depletion coupled to SRM: correlation with clinical immunoassay tests | |
| JP2002542820A5 (enExample) | ||
| US5840501A (en) | Determination of cPSA | |
| EP0104527A1 (en) | Digoxigenin immunogens, antibodies, labeled conjugates, and related derivatives | |
| CA2193323C (en) | Process for preparing a synthetic calibrator for use in sandwich immunoassays, which calibrator consists of an antibody against one of the antibodies used in the assay and of a sequence of the analyte | |
| JPH05504481A (ja) | 改良された抗体―酵素直接接合体及びその製造方法 | |
| US20070254317A1 (en) | Method for Detecting the Activatable Free Form of Psa and the Use Thereof for Diagnosing Benign Pathologies of the Prostate and Adenocarcinoma of the Prostate | |
| US6379550B1 (en) | Method for detecting PSA and its molecular forms using thiophilic gel | |
| JP4447796B2 (ja) | 前立腺癌と良性前立腺肥大とを識別する方法 | |
| JP2000095799A (ja) | 抗体のフレ―ムワ―ク領域から誘導される物質によるイムノアッセイの干渉の減少 | |
| Jung et al. | Different stability of free and complexed prostate-specific antigen in serum in relation to specimen handling and storage conditions | |
| US6686167B2 (en) | Test device for detecting semen and method of use | |
| KR910700463A (ko) | 암과 관련된 헵토글로빈 | |
| Torrente-Rodríguez et al. | Rapid endoglin determination in serum samples using an amperometric magneto-actuated disposable immunosensing platform | |
| EP1007570A4 (en) | Monospecific antibody reactive with fibrinogen and fibrinopeptide b | |
| JPH05295000A (ja) | 共有結合的交雑種抗体、その調製法およびこれを使用する均質的免疫検定法 | |
| EP0095089A1 (en) | Improved homogeneous binding assay method and reagent system, test kit and test device therefor | |
| JPH07191027A (ja) | 糖蛋白質の分別測定法 | |
| JP2002538818A5 (enExample) | ||
| JPH0566223A (ja) | 高分量分析物の測定法 | |
| JP2702616B2 (ja) | Ｐｉｖｋａ−ｉｉの測定試薬 | |
| JPS583671B2 (ja) | アポグルコ−スオキシダ−ゼの、フラビンアデニンジヌクレオチド及びその誘導体と結合する能力を増大する方法、複合体並びに液体媒体中のリガンドを測定するための均一系特異的結合分析法、均一系免疫分析法、試薬及 |