JP2002542305A5 - - Google Patents
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- Publication number
- JP2002542305A5 JP2002542305A5 JP2000613478A JP2000613478A JP2002542305A5 JP 2002542305 A5 JP2002542305 A5 JP 2002542305A5 JP 2000613478 A JP2000613478 A JP 2000613478A JP 2000613478 A JP2000613478 A JP 2000613478A JP 2002542305 A5 JP2002542305 A5 JP 2002542305A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- epitope
- cell
- nucleic acid
- interleukin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 description 49
- 150000007523 nucleic acids Chemical group 0.000 description 27
- 108020004707 nucleic acids Proteins 0.000 description 20
- 102000039446 nucleic acids Human genes 0.000 description 20
- 210000001744 T-lymphocyte Anatomy 0.000 description 14
- 108060003951 Immunoglobulin Proteins 0.000 description 12
- 230000005867 T cell response Effects 0.000 description 12
- 102000018358 immunoglobulin Human genes 0.000 description 12
- 102000004127 Cytokines Human genes 0.000 description 8
- 108090000695 Cytokines Proteins 0.000 description 8
- 210000003563 lymphoid tissue Anatomy 0.000 description 8
- 108091028043 Nucleic acid sequence Proteins 0.000 description 7
- 210000003719 b-lymphocyte Anatomy 0.000 description 7
- 229920001184 polypeptide Polymers 0.000 description 7
- 102000004196 processed proteins & peptides Human genes 0.000 description 7
- 108090000765 processed proteins & peptides Proteins 0.000 description 7
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 6
- 102000003814 Interleukin-10 Human genes 0.000 description 5
- 108090000174 Interleukin-10 Proteins 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 229940076144 interleukin-10 Drugs 0.000 description 5
- 108010047041 Complementarity Determining Regions Proteins 0.000 description 4
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 description 4
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 description 4
- 108010074328 Interferon-gamma Proteins 0.000 description 4
- 102000008070 Interferon-gamma Human genes 0.000 description 4
- 108010002350 Interleukin-2 Proteins 0.000 description 4
- 102000000588 Interleukin-2 Human genes 0.000 description 4
- 102000004388 Interleukin-4 Human genes 0.000 description 4
- 108090000978 Interleukin-4 Proteins 0.000 description 4
- 108010002616 Interleukin-5 Proteins 0.000 description 4
- 102000000743 Interleukin-5 Human genes 0.000 description 4
- 102000004889 Interleukin-6 Human genes 0.000 description 4
- 108090001005 Interleukin-6 Proteins 0.000 description 4
- 230000005875 antibody response Effects 0.000 description 4
- 230000004927 fusion Effects 0.000 description 4
- 229960003130 interferon gamma Drugs 0.000 description 4
- 229940028885 interleukin-4 Drugs 0.000 description 4
- 229940100602 interleukin-5 Drugs 0.000 description 4
- 229940100601 interleukin-6 Drugs 0.000 description 4
- 210000004698 lymphocyte Anatomy 0.000 description 4
- 230000004936 stimulating effect Effects 0.000 description 3
- 102000015696 Interleukins Human genes 0.000 description 2
- 108010063738 Interleukins Proteins 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 210000001165 lymph node Anatomy 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 210000002741 palatine tonsil Anatomy 0.000 description 2
- 210000001986 peyer's patch Anatomy 0.000 description 2
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 description 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 description 1
- 108010066979 Interleukin-27 Proteins 0.000 description 1
- 102100036678 Interleukin-27 subunit alpha Human genes 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/300,959 US7279462B1 (en) | 1998-04-27 | 1999-04-27 | Somatic transgene immunization and related methods |
| US09/300,959 | 1999-04-27 | ||
| PCT/US2000/011372 WO2000064488A2 (en) | 1999-04-27 | 2000-04-27 | Somatic transgene immunization and related methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008328814A Division JP2009102369A (ja) | 1999-04-27 | 2008-12-24 | 体細胞導入遺伝子免疫および関連方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002542305A JP2002542305A (ja) | 2002-12-10 |
| JP2002542305A5 true JP2002542305A5 (enExample) | 2008-02-14 |
| JP5000807B2 JP5000807B2 (ja) | 2012-08-15 |
Family
ID=23161331
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000613478A Expired - Fee Related JP5000807B2 (ja) | 1999-04-27 | 2000-04-27 | 体細胞導入遺伝子免疫および関連方法 |
| JP2008328814A Pending JP2009102369A (ja) | 1999-04-27 | 2008-12-24 | 体細胞導入遺伝子免疫および関連方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008328814A Pending JP2009102369A (ja) | 1999-04-27 | 2008-12-24 | 体細胞導入遺伝子免疫および関連方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080076175A1 (enExample) |
| EP (1) | EP1181320B1 (enExample) |
| JP (2) | JP5000807B2 (enExample) |
| AT (1) | ATE501175T1 (enExample) |
| CA (1) | CA2369616C (enExample) |
| DE (1) | DE60045707D1 (enExample) |
| WO (1) | WO2000064488A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7279462B1 (en) | 1998-04-27 | 2007-10-09 | Nevagen Llc | Somatic transgene immunization and related methods |
| GB0102145D0 (en) | 2001-01-26 | 2001-03-14 | Scancell Ltd | Substances |
| EP1887084A1 (en) * | 2006-08-10 | 2008-02-13 | International Investment and Patents SA | Plasmids with immunological action |
| GB0706070D0 (en) | 2007-03-28 | 2007-05-09 | Scancell Ltd | Nucleic acids |
| JOP20190271A1 (ar) * | 2017-05-24 | 2019-11-21 | Novartis Ag | بروتينات مطعّمة بسيتوكين- الجسم المضاد وطرق الاستخدام للاضطرابات المتعلقة بالمناعة |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69023900D1 (de) * | 1989-02-24 | 1996-01-11 | Univ California | Gentechnologisch veränderte immunglobuline. |
| US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5969109A (en) * | 1990-02-28 | 1999-10-19 | Bona; Constantin | Chimeric antibodies comprising antigen binding sites and B and T cell epitopes |
| US6977074B2 (en) * | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
| US5891432A (en) * | 1997-07-29 | 1999-04-06 | The Immune Response Corporation | Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same |
| US7279462B1 (en) * | 1998-04-27 | 2007-10-09 | Nevagen Llc | Somatic transgene immunization and related methods |
| US6306640B1 (en) * | 1998-10-05 | 2001-10-23 | Genzyme Corporation | Melanoma antigenic peptides |
-
2000
- 2000-04-27 WO PCT/US2000/011372 patent/WO2000064488A2/en not_active Ceased
- 2000-04-27 AT AT00930184T patent/ATE501175T1/de not_active IP Right Cessation
- 2000-04-27 JP JP2000613478A patent/JP5000807B2/ja not_active Expired - Fee Related
- 2000-04-27 EP EP00930184A patent/EP1181320B1/en not_active Expired - Lifetime
- 2000-04-27 CA CA002369616A patent/CA2369616C/en not_active Expired - Fee Related
- 2000-04-27 DE DE60045707T patent/DE60045707D1/de not_active Expired - Lifetime
-
2007
- 2007-03-01 US US11/713,477 patent/US20080076175A1/en not_active Abandoned
-
2008
- 2008-12-24 JP JP2008328814A patent/JP2009102369A/ja active Pending
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