JP5000807B2 - 体細胞導入遺伝子免疫および関連方法 - Google Patents

体細胞導入遺伝子免疫および関連方法 Download PDF

Info

Publication number
JP5000807B2
JP5000807B2 JP2000613478A JP2000613478A JP5000807B2 JP 5000807 B2 JP5000807 B2 JP 5000807B2 JP 2000613478 A JP2000613478 A JP 2000613478A JP 2000613478 A JP2000613478 A JP 2000613478A JP 5000807 B2 JP5000807 B2 JP 5000807B2
Authority
JP
Japan
Prior art keywords
cell
cells
composition
nucleic acid
mice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000613478A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002542305A5 (enExample
JP2002542305A (ja
Inventor
マウリジオ ザネッティ,
Original Assignee
ネバジェン エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23161331&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP5000807(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/300,959 external-priority patent/US7279462B1/en
Application filed by ネバジェン エルエルシー filed Critical ネバジェン エルエルシー
Publication of JP2002542305A publication Critical patent/JP2002542305A/ja
Publication of JP2002542305A5 publication Critical patent/JP2002542305A5/ja
Application granted granted Critical
Publication of JP5000807B2 publication Critical patent/JP5000807B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70517—CD8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Biological Depolymerization Polymers (AREA)
JP2000613478A 1999-04-27 2000-04-27 体細胞導入遺伝子免疫および関連方法 Expired - Fee Related JP5000807B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/300,959 US7279462B1 (en) 1998-04-27 1999-04-27 Somatic transgene immunization and related methods
US09/300,959 1999-04-27
PCT/US2000/011372 WO2000064488A2 (en) 1999-04-27 2000-04-27 Somatic transgene immunization and related methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008328814A Division JP2009102369A (ja) 1999-04-27 2008-12-24 体細胞導入遺伝子免疫および関連方法

Publications (3)

Publication Number Publication Date
JP2002542305A JP2002542305A (ja) 2002-12-10
JP2002542305A5 JP2002542305A5 (enExample) 2008-02-14
JP5000807B2 true JP5000807B2 (ja) 2012-08-15

Family

ID=23161331

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000613478A Expired - Fee Related JP5000807B2 (ja) 1999-04-27 2000-04-27 体細胞導入遺伝子免疫および関連方法
JP2008328814A Pending JP2009102369A (ja) 1999-04-27 2008-12-24 体細胞導入遺伝子免疫および関連方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008328814A Pending JP2009102369A (ja) 1999-04-27 2008-12-24 体細胞導入遺伝子免疫および関連方法

Country Status (7)

Country Link
US (1) US20080076175A1 (enExample)
EP (1) EP1181320B1 (enExample)
JP (2) JP5000807B2 (enExample)
AT (1) ATE501175T1 (enExample)
CA (1) CA2369616C (enExample)
DE (1) DE60045707D1 (enExample)
WO (1) WO2000064488A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7279462B1 (en) 1998-04-27 2007-10-09 Nevagen Llc Somatic transgene immunization and related methods
GB0102145D0 (en) 2001-01-26 2001-03-14 Scancell Ltd Substances
EP1887084A1 (en) * 2006-08-10 2008-02-13 International Investment and Patents SA Plasmids with immunological action
GB0706070D0 (en) 2007-03-28 2007-05-09 Scancell Ltd Nucleic acids
JOP20190271A1 (ar) * 2017-05-24 2019-11-21 Novartis Ag بروتينات مطعّمة بسيتوكين- الجسم المضاد وطرق الاستخدام للاضطرابات المتعلقة بالمناعة

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69023900D1 (de) * 1989-02-24 1996-01-11 Univ California Gentechnologisch veränderte immunglobuline.
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5969109A (en) * 1990-02-28 1999-10-19 Bona; Constantin Chimeric antibodies comprising antigen binding sites and B and T cell epitopes
US6977074B2 (en) * 1997-07-10 2005-12-20 Mannkind Corporation Method of inducing a CTL response
US5891432A (en) * 1997-07-29 1999-04-06 The Immune Response Corporation Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same
US7279462B1 (en) * 1998-04-27 2007-10-09 Nevagen Llc Somatic transgene immunization and related methods
US6306640B1 (en) * 1998-10-05 2001-10-23 Genzyme Corporation Melanoma antigenic peptides

Also Published As

Publication number Publication date
WO2000064488A2 (en) 2000-11-02
JP2002542305A (ja) 2002-12-10
DE60045707D1 (de) 2011-04-21
EP1181320B1 (en) 2011-03-09
WO2000064488A3 (en) 2001-05-10
CA2369616C (en) 2009-09-15
ATE501175T1 (de) 2011-03-15
US20080076175A1 (en) 2008-03-27
WO2000064488A9 (en) 2002-07-11
JP2009102369A (ja) 2009-05-14
CA2369616A1 (en) 2000-11-02
EP1181320A2 (en) 2002-02-27

Similar Documents

Publication Publication Date Title
JP4764585B2 (ja) タンパク質抗原およびペプチド抗原の免疫原性を増強するためのfc融合タンパク質
US7118751B1 (en) DNA vaccines encoding antigen linked to a domain that binds CD40
US7067110B1 (en) Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
CN114404584B (zh) 一种新型冠状病毒mRNA疫苗及其制备方法和用途
TW201938793A (zh) 一種新型疫苗佐劑
US20130183347A1 (en) Somatic Transgene Immunization and Related Methods
JP2009102369A (ja) 体細胞導入遺伝子免疫および関連方法
JP2023550004A (ja) 融合遺伝子、組換え新型コロナウイルス高効率免疫dnaワクチン、それらの構築方法及び使用
US11666649B2 (en) Vectors and vaccine cells for immunity against Zika virus
US20130236456A1 (en) IMMUNOGLOBULIN Fc FRAGMENT TAGGING ACTIVATION OF ENDOGENOUS CD4 AND CD8 T CELLS AND ENHANCEMENT OF ANTITUMOR EFFECTS OF LENTIVECTOR IMMUNIZATION
MX2007004734A (es) Combinacion de una micobateria recombinante y un agente biologicamente activo como una vacuna.
US20090074814A1 (en) DNA Vaccines Encoding Antigen Linked to a Domain That Binds CD40
EP1355946B1 (en) Dna vaccines expressing hypervariable vh-cdr3 idiotipic determinants
Klein et al. Applications of immunochemistry in human health: advances in vaccinology and antibody design (IUPAC Technical Report)
KR20220041080A (ko) B형 간염 바이러스(hbv) 백신 및 항-pd-1 또는 항-pc-l1 항체의 조합
WO2023215560A1 (en) Tumor cell/immune cell multivalent receptor engager – bio-nanoparticle (timre-bnp)
Mažeikė Generation of anticancer vaccine based on virus-like particles

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20061229

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20070109

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20070314

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20070608

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20070608

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20070608

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20070710

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20070808

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20070913

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20071116

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20080104

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20080825

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20081224

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20090312

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20090501

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110523

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110526

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110721

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110726

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111221

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111227

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120327

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20120517

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20150525

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees