JP2002540208A5 - - Google Patents

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Publication number
JP2002540208A5
JP2002540208A5 JP2000608013A JP2000608013A JP2002540208A5 JP 2002540208 A5 JP2002540208 A5 JP 2002540208A5 JP 2000608013 A JP2000608013 A JP 2000608013A JP 2000608013 A JP2000608013 A JP 2000608013A JP 2002540208 A5 JP2002540208 A5 JP 2002540208A5
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JP
Japan
Prior art keywords
group
formula
alkyl
alkoxy
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000608013A
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English (en)
Japanese (ja)
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JP2002540208A (ja
JP4500454B2 (ja
Filing date
Publication date
Priority claimed from FR9903934A external-priority patent/FR2791678B1/fr
Application filed filed Critical
Publication of JP2002540208A publication Critical patent/JP2002540208A/ja
Publication of JP2002540208A5 publication Critical patent/JP2002540208A5/ja
Application granted granted Critical
Publication of JP4500454B2 publication Critical patent/JP4500454B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000608013A 1999-03-30 2000-03-21 1,4−ジアザビシクロ[3.2.2]ノナン−4−カルボキシレートおよびカルボキサミド誘導体、治療におけるその製造ならびに使用 Expired - Fee Related JP4500454B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR99/03934 1999-03-30
FR9903934A FR2791678B1 (fr) 1999-03-30 1999-03-30 Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique
PCT/FR2000/000697 WO2000058311A1 (fr) 1999-03-30 2000-03-21 Derives de 1,4-diazabicyclo[3.2.2]nonane-4-carboxylates et carboxamides, leur preparation et leur application en therapeutique

Publications (3)

Publication Number Publication Date
JP2002540208A JP2002540208A (ja) 2002-11-26
JP2002540208A5 true JP2002540208A5 (US20080131398A1-20080605-C00009.png) 2006-09-14
JP4500454B2 JP4500454B2 (ja) 2010-07-14

Family

ID=9543787

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000608013A Expired - Fee Related JP4500454B2 (ja) 1999-03-30 2000-03-21 1,4−ジアザビシクロ[3.2.2]ノナン−4−カルボキシレートおよびカルボキサミド誘導体、治療におけるその製造ならびに使用

Country Status (15)

Country Link
US (1) US6987106B1 (US20080131398A1-20080605-C00009.png)
EP (1) EP1165559B1 (US20080131398A1-20080605-C00009.png)
JP (1) JP4500454B2 (US20080131398A1-20080605-C00009.png)
AR (1) AR023188A1 (US20080131398A1-20080605-C00009.png)
AT (1) ATE232865T1 (US20080131398A1-20080605-C00009.png)
AU (1) AU3301800A (US20080131398A1-20080605-C00009.png)
CO (1) CO5180557A1 (US20080131398A1-20080605-C00009.png)
DE (1) DE60001451T2 (US20080131398A1-20080605-C00009.png)
DK (1) DK1165559T3 (US20080131398A1-20080605-C00009.png)
ES (1) ES2192520T3 (US20080131398A1-20080605-C00009.png)
FR (1) FR2791678B1 (US20080131398A1-20080605-C00009.png)
PE (1) PE20001600A1 (US20080131398A1-20080605-C00009.png)
TW (1) TWI221843B (US20080131398A1-20080605-C00009.png)
UY (1) UY26082A1 (US20080131398A1-20080605-C00009.png)
WO (1) WO2000058311A1 (US20080131398A1-20080605-C00009.png)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852721B2 (en) 2000-05-25 2005-02-08 Targacept, Inc. Pharmaceutical compositions and methods for use
US6624167B1 (en) 2000-08-04 2003-09-23 Targacept, Inc. Pharmaceutical compositions and methods for use
EP1231212B1 (en) * 2001-02-06 2006-12-20 Pfizer Products Inc. Pharmaceutical compositions for the treatment of disorders of the CNS and other disorders
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
SE0202430D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
SE0202465D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
SK288115B6 (sk) 2002-09-25 2013-09-03 Memory Pharmaceuticals Corporation Indazoles, pharmaceutical compositions comprising them and their use
EP1599476B1 (en) * 2003-02-27 2009-10-14 Neurosearch A/S Novel diazabicyclic aryl derivatives
CN100445285C (zh) * 2003-12-22 2008-12-24 阿斯利康(瑞典)有限公司 烟碱性乙酰胆碱受体配体
TW200529860A (en) * 2003-12-22 2005-09-16 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
WO2005063767A2 (en) 2003-12-22 2005-07-14 Memory Pharmaceuticals Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof
EP1713810B1 (en) * 2004-02-04 2010-12-29 NeuroSearch A/S Diazabicyclic aryl derivatives as nicotinic acetylcholine receptor ligands
BRPI0508771A (pt) 2004-03-25 2007-08-14 Memory Pharm Corp indazóis, benzotiazóis, benzoisotiazóis, benzisoxazóis, e a preparação e usos dos mesmos
EP1742944B1 (en) 2004-04-22 2010-11-10 Memory Pharmaceuticals Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
US7632831B2 (en) * 2004-05-07 2009-12-15 Memory Pharmaceuticals Corporation 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
US7652010B2 (en) 2004-10-15 2010-01-26 Neurosearch A/S Azabicyclic aryl derivatives and their medical use
WO2006069097A2 (en) 2004-12-22 2006-06-29 Memory Pharmaceuticals Corporation Nicotinic alpha-7 receptor ligands and preparation and uses thereof
US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
JP2009526776A (ja) * 2006-02-14 2009-07-23 ノイロサーチ アクティーゼルスカブ 新規なジアザビシクロアルカン誘導体及びその医療上の使用
JP2007217370A (ja) * 2006-02-17 2007-08-30 Nard Inst Ltd ポジトロン断層撮影法および該方法に用いるポジトロン放出化合物
JP2009537598A (ja) 2006-05-23 2009-10-29 ノイロサーチ アクティーゼルスカブ 新規1,4−ジアザ−ビシクロ[3.2.2]ノナン誘導体及びそれらの医学的使用
US20100234349A1 (en) 2006-09-04 2010-09-16 Olsen Gunnar M Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer
WO2008119710A1 (en) * 2007-03-30 2008-10-09 Neurosearch A/S Two-phase test method for characterizing the effect of a chemical compound on a test animal and maze for carrying out the method
SA08290475B1 (ar) 2007-08-02 2013-06-22 Targacept Inc (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
FR2931677B1 (fr) * 2008-06-02 2010-08-20 Sanofi Aventis Association d'un agoniste partiel des recepteurs nicotiniques et d'un inhibiteur d'acetylcholinesterase, composition la contenant et son utilisation dans le traitement des troubles cognitifs
FR2931823B1 (fr) 2008-06-02 2012-08-17 Sanofi Aventis Sel de fumarate du 1,4-diazabicyclo°3.2.2!nonane-carboxylate de 4-bromophenyle, ses formes cristallines, leur preparation et leur utilisation en therapeutique
WO2010059844A1 (en) 2008-11-19 2010-05-27 Envivo Pharmaceuticals, Inc. Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
CN102802620A (zh) * 2009-05-11 2012-11-28 英维沃医药有限公司 使用某种α-7烟酸受体与乙酰胆碱酯酶抑制剂结合治疗认知障碍
PT3029039T (pt) 2010-05-17 2017-11-28 Forum Pharmaceuticals Inc Formulações farmacêuticas que compreendem formas cristalinas de cloridrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo(b)tiofeno-2-carboxamida mono-hidratado
MX365245B (es) * 2011-03-18 2019-05-28 Genzyme Corp Inhibidores de glucosilceramida sintasa.
AU2013259871A1 (en) 2012-05-08 2014-11-20 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function
MA37975B2 (fr) 2012-09-11 2021-03-31 Genzyme Corp Inhibiteurs de synthase de glucosylcéramide
MX2023001014A (es) 2020-07-24 2023-03-01 Genzyme Corp Composiciones farmaceuticas que comprenden venglustat.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235878A3 (en) * 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
JP2668670B2 (ja) * 1995-03-24 1997-10-27 日本たばこ産業株式会社 ジアザビシクロ[3.3.1]ノナン誘導体、その中間体及びその医薬用途
JP2002511090A (ja) * 1997-06-30 2002-04-09 アール・ジェイ・レイノルズ・タバコ・カンパニー Cns疾患の予防と治療用3−ピリジル−1−アザ−ビシクロ−アルカン誘導体

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