JP2002538818A - 前立腺腫瘍組織におけるヒトカリクレイン２とプロテアーゼインヒビター−６の新規な複合体および該複合体の利用方法 - Google Patents

前立腺腫瘍組織におけるヒトカリクレイン２とプロテアーゼインヒビター−６の新規な複合体および該複合体の利用方法

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Publication number
JP2002538818A
JP2002538818A JP2000605726A JP2000605726A JP2002538818A JP 2002538818 A JP2002538818 A JP 2002538818A JP 2000605726 A JP2000605726 A JP 2000605726A JP 2000605726 A JP2000605726 A JP 2000605726A JP 2002538818 A JP2002538818 A JP 2002538818A
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JP
Japan
Prior art keywords
complex
antibody
sample
reagent
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000605726A
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English (en)
Japanese (ja)
Other versions
JP2002538818A5 (enExample
Inventor
スティーブン ミコライクジク、
モハマド サエディ、
Original Assignee
ハイブリテック インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by ハイブリテック インコーポレイテッド filed Critical ハイブリテック インコーポレイテッド
Publication of JP2002538818A publication Critical patent/JP2002538818A/ja
Publication of JP2002538818A5 publication Critical patent/JP2002538818A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/803—Stabe free radicals, e.g. spin immunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2000605726A 1999-03-12 2000-01-26 前立腺腫瘍組織におけるヒトカリクレイン２とプロテアーゼインヒビター−６の新規な複合体および該複合体の利用方法 Pending JP2002538818A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/266,957 US6284873B1 (en) 1999-03-12 1999-03-12 Complex of human kallikrein 2 (hK2) and protease inhibitor-6 (PI-6) in prostate tumor tissue and methods of using the complex
US09/266,957 1999-03-12
PCT/US2000/001937 WO2000055308A1 (en) 1999-03-12 2000-01-26 A NOVEL COMPLEX OF HUMAN KALLIKREIN 2 (hK2) AND PROTEASE INHIBITOR-6 (PI-6) IN PROSTATE TUMOR TISSUE AND METHODS OF USING THE COMPLEX

Publications (2)

Publication Number Publication Date
JP2002538818A true JP2002538818A (ja) 2002-11-19
JP2002538818A5 JP2002538818A5 (enExample) 2007-03-08

Family

ID=23016693

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000605726A Pending JP2002538818A (ja) 1999-03-12 2000-01-26 前立腺腫瘍組織におけるヒトカリクレイン２とプロテアーゼインヒビター−６の新規な複合体および該複合体の利用方法

Country Status (6)

Country Link
US (3) US6284873B1 (enExample)
EP (1) EP1159411A1 (enExample)
JP (1) JP2002538818A (enExample)
AU (1) AU778038B2 (enExample)
CA (1) CA2365540A1 (enExample)
WO (1) WO2000055308A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009509169A (ja) * 2005-09-19 2009-03-05 ザ・ジョンズ・ホプキンス・ユニバーシティ 前立腺癌のためのバイオマーカー
JP2023125474A (ja) * 2022-02-28 2023-09-07 住友ベークライト株式会社 セリンプロテアーゼの検出用または測定用試薬

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1798838B (zh) 2003-04-04 2012-01-04 洛桑大学 一种蛋白酶的抑制剂蛋白及其用途
US20040242461A1 (en) * 2003-04-08 2004-12-02 Schneider Michael D. Modulators of telomere stability
ATE403448T1 (de) * 2003-04-28 2008-08-15 Johnson & Johnson Medical Ltd Schmerz-empfindliche therapeutische wundverbände
GB2408207A (en) 2003-11-24 2005-05-25 Johnson & Johnson Medical Ltd Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme
US9347946B2 (en) * 2010-09-23 2016-05-24 Biocept, Inc. Methods and reagents for signal amplification

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4731326A (en) * 1984-06-04 1988-03-15 Ortho Diagnostic Systems Inc. Disease diagnosis by detection of shed normal tissue antigens
US5730968A (en) * 1994-03-31 1998-03-24 Sterling Winthrop Inc. Segmented chelating polymers as imaging and therapeutic agents

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009509169A (ja) * 2005-09-19 2009-03-05 ザ・ジョンズ・ホプキンス・ユニバーシティ 前立腺癌のためのバイオマーカー
JP2023125474A (ja) * 2022-02-28 2023-09-07 住友ベークライト株式会社 セリンプロテアーゼの検出用または測定用試薬
JP7355140B2 (ja) 2022-02-28 2023-10-03 住友ベークライト株式会社 セリンプロテアーゼの検出用または測定用試薬

Also Published As

Publication number Publication date
AU2737600A (en) 2000-10-04
US6284873B1 (en) 2001-09-04
AU778038B2 (en) 2004-11-11
EP1159411A1 (en) 2001-12-05
US6472143B1 (en) 2002-10-29
CA2365540A1 (en) 2000-09-21
WO2000055308A1 (en) 2000-09-21
US20010031860A1 (en) 2001-10-18

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