JP2002538778A - 蛋白質を無細胞合成するための装置 - Google Patents

蛋白質を無細胞合成するための装置

Info

Publication number
JP2002538778A
JP2002538778A JP2000596122A JP2000596122A JP2002538778A JP 2002538778 A JP2002538778 A JP 2002538778A JP 2000596122 A JP2000596122 A JP 2000596122A JP 2000596122 A JP2000596122 A JP 2000596122A JP 2002538778 A JP2002538778 A JP 2002538778A
Authority
JP
Japan
Prior art keywords
chamber
supply
module
membrane
supply chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000596122A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002538778A5 (https=
Inventor
シュルス、ハンス
メンツレル、ホルスト
フィシェル、ウルリケ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of JP2002538778A publication Critical patent/JP2002538778A/ja
Publication of JP2002538778A5 publication Critical patent/JP2002538778A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2000596122A 1999-01-27 2000-01-21 蛋白質を無細胞合成するための装置 Pending JP2002538778A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99101418.4 1999-01-27
EP99101418 1999-01-27
PCT/DE2000/000190 WO2000044877A1 (de) 1999-01-27 2000-01-21 Vorrichtung zur zellfreien synthese von proteinen

Publications (2)

Publication Number Publication Date
JP2002538778A true JP2002538778A (ja) 2002-11-19
JP2002538778A5 JP2002538778A5 (https=) 2006-11-02

Family

ID=8237415

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000596122A Pending JP2002538778A (ja) 1999-01-27 2000-01-21 蛋白質を無細胞合成するための装置

Country Status (7)

Country Link
US (1) US6670173B1 (https=)
EP (1) EP1144587B1 (https=)
JP (1) JP2002538778A (https=)
AT (1) ATE245693T1 (https=)
CA (1) CA2360077A1 (https=)
DE (2) DE50002990D1 (https=)
WO (1) WO2000044877A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20305570U1 (de) 2003-04-07 2004-05-13 Roche Diagnostics Gmbh Mehrkammer-Mikrodialysevorrichtung
WO2006017274A2 (en) * 2004-07-13 2006-02-16 U.S. Genomics, Inc. Systems and methods for sample modification using fluidic chambers
WO2007021919A1 (en) 2005-08-12 2007-02-22 Clemson University Co-culture bioreactor system
US20070117179A1 (en) * 2005-09-27 2007-05-24 Invitrogen Corporation In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles
US20080248565A1 (en) * 2007-03-01 2008-10-09 Invitrogen Corporation Isolated phospholipid-protein particles
US9057044B2 (en) 2006-08-30 2015-06-16 Meir Israelowitz Laminar flow reactor
US20090215176A1 (en) * 2008-02-25 2009-08-27 Clemson University Differential Pressure Pump System
US8808541B2 (en) * 2008-03-03 2014-08-19 Marwan Nasralla Dialysis cell and tray for dialysis cells
US10774304B2 (en) * 2011-03-08 2020-09-15 University Of Maryland, Baltimore County System and method for production of on-demand proteins in a portable unit for point of care delivery
US12227734B2 (en) 2011-03-08 2025-02-18 University Of Maryland, Baltimore County Microscale bioprocessing system and method for protein manufacturing from human blood
US9388373B2 (en) * 2011-03-08 2016-07-12 University Of Maryland Baltimore County Microscale bioprocessing system and method for protein manufacturing
US9982227B2 (en) 2011-03-08 2018-05-29 University Of Maryland, Baltimore County System and method for production of on-demand proteins in a portable unit for point of care delivery
US11421226B2 (en) * 2018-10-17 2022-08-23 Ramot At Tel-Aviv University Ltd. Programmable artificial cell
US11235997B2 (en) * 2019-04-25 2022-02-01 The Boeing Company Anaerobic waste treatment system for vehicles
CN115279879A (zh) * 2019-11-15 2022-11-01 机器生物公司 生成生物分子的方法和系统
WO2023094884A1 (en) * 2021-11-24 2023-06-01 Liberum Biotech Inc. Methods and apparatuses for scaling up cell-free synthesis reactions
US20240299929A1 (en) * 2023-03-09 2024-09-12 Tamara Krstic Compartamentalizing bioreactor device and separation machinery
EP4516392A1 (en) 2023-09-04 2025-03-05 Vito NV Peptides, peptidic nucleic acids (pna) and oligonucleotides synthesis assisted by membrane extraction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478730A (en) * 1988-12-21 1995-12-26 Institute Of Protein Research Method of preparing polypeptides in cell-free translation system
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
FR2667874B1 (fr) * 1990-10-16 1992-12-31 Rhone Alpes Futur Fondation Reacteur bio-catalyse, et procede de traitement correspondant, applicables notamment a la transformation malolactique du vin.
US5434079A (en) * 1993-02-12 1995-07-18 The United States Of America As Represented By The Department Of Health And Human Services Apparatus and process for continuous in vitro synthesis of proteins
US5599688A (en) * 1993-10-18 1997-02-04 Precision Instrument Design Device and method for circulating fluid over a membrane
US5591636A (en) * 1993-10-18 1997-01-07 Precision Instrument Design Membrane holder
US5688687A (en) * 1995-06-07 1997-11-18 Aastrom Biosciences, Inc. Bioreactor for mammalian cell growth and maintenance
EP0894852B1 (de) * 1997-07-31 2004-01-28 Roche Diagnostics GmbH Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen

Also Published As

Publication number Publication date
US6670173B1 (en) 2003-12-30
EP1144587A1 (de) 2001-10-17
DE10080164D2 (de) 2001-12-13
WO2000044877A1 (de) 2000-08-03
CA2360077A1 (en) 2000-08-03
EP1144587B1 (de) 2003-07-23
ATE245693T1 (de) 2003-08-15
DE50002990D1 (de) 2003-08-28

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