DE50002990D1 - Vorrichtung zum zellfreie synthese von proteine - Google Patents

Vorrichtung zum zellfreie synthese von proteine

Info

Publication number
DE50002990D1
DE50002990D1 DE50002990T DE50002990T DE50002990D1 DE 50002990 D1 DE50002990 D1 DE 50002990D1 DE 50002990 T DE50002990 T DE 50002990T DE 50002990 T DE50002990 T DE 50002990T DE 50002990 D1 DE50002990 D1 DE 50002990D1
Authority
DE
Germany
Prior art keywords
chamber
semi
supply
permeable membrane
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE50002990T
Other languages
German (de)
English (en)
Inventor
Hans Schels
Horst Menzler
Ulrike Fischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of DE50002990D1 publication Critical patent/DE50002990D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE50002990T 1999-01-27 2000-01-21 Vorrichtung zum zellfreie synthese von proteine Expired - Fee Related DE50002990D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99101418 1999-01-27
PCT/DE2000/000190 WO2000044877A1 (de) 1999-01-27 2000-01-21 Vorrichtung zur zellfreien synthese von proteinen

Publications (1)

Publication Number Publication Date
DE50002990D1 true DE50002990D1 (de) 2003-08-28

Family

ID=8237415

Family Applications (2)

Application Number Title Priority Date Filing Date
DE50002990T Expired - Fee Related DE50002990D1 (de) 1999-01-27 2000-01-21 Vorrichtung zum zellfreie synthese von proteine
DE10080164T Ceased DE10080164D2 (de) 1999-01-27 2000-01-21 Vorrichtung zur zellfreien Synthese von Proteinen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10080164T Ceased DE10080164D2 (de) 1999-01-27 2000-01-21 Vorrichtung zur zellfreien Synthese von Proteinen

Country Status (7)

Country Link
US (1) US6670173B1 (https=)
EP (1) EP1144587B1 (https=)
JP (1) JP2002538778A (https=)
AT (1) ATE245693T1 (https=)
CA (1) CA2360077A1 (https=)
DE (2) DE50002990D1 (https=)
WO (1) WO2000044877A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20305570U1 (de) 2003-04-07 2004-05-13 Roche Diagnostics Gmbh Mehrkammer-Mikrodialysevorrichtung
WO2006017274A2 (en) * 2004-07-13 2006-02-16 U.S. Genomics, Inc. Systems and methods for sample modification using fluidic chambers
WO2007021919A1 (en) 2005-08-12 2007-02-22 Clemson University Co-culture bioreactor system
US20070117179A1 (en) * 2005-09-27 2007-05-24 Invitrogen Corporation In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles
US20080248565A1 (en) * 2007-03-01 2008-10-09 Invitrogen Corporation Isolated phospholipid-protein particles
US9057044B2 (en) 2006-08-30 2015-06-16 Meir Israelowitz Laminar flow reactor
US20090215176A1 (en) * 2008-02-25 2009-08-27 Clemson University Differential Pressure Pump System
US8808541B2 (en) * 2008-03-03 2014-08-19 Marwan Nasralla Dialysis cell and tray for dialysis cells
US10774304B2 (en) * 2011-03-08 2020-09-15 University Of Maryland, Baltimore County System and method for production of on-demand proteins in a portable unit for point of care delivery
US12227734B2 (en) 2011-03-08 2025-02-18 University Of Maryland, Baltimore County Microscale bioprocessing system and method for protein manufacturing from human blood
US9388373B2 (en) * 2011-03-08 2016-07-12 University Of Maryland Baltimore County Microscale bioprocessing system and method for protein manufacturing
US9982227B2 (en) 2011-03-08 2018-05-29 University Of Maryland, Baltimore County System and method for production of on-demand proteins in a portable unit for point of care delivery
US11421226B2 (en) * 2018-10-17 2022-08-23 Ramot At Tel-Aviv University Ltd. Programmable artificial cell
US11235997B2 (en) * 2019-04-25 2022-02-01 The Boeing Company Anaerobic waste treatment system for vehicles
CN115279879A (zh) * 2019-11-15 2022-11-01 机器生物公司 生成生物分子的方法和系统
WO2023094884A1 (en) * 2021-11-24 2023-06-01 Liberum Biotech Inc. Methods and apparatuses for scaling up cell-free synthesis reactions
US20240299929A1 (en) * 2023-03-09 2024-09-12 Tamara Krstic Compartamentalizing bioreactor device and separation machinery
EP4516392A1 (en) 2023-09-04 2025-03-05 Vito NV Peptides, peptidic nucleic acids (pna) and oligonucleotides synthesis assisted by membrane extraction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478730A (en) * 1988-12-21 1995-12-26 Institute Of Protein Research Method of preparing polypeptides in cell-free translation system
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
FR2667874B1 (fr) * 1990-10-16 1992-12-31 Rhone Alpes Futur Fondation Reacteur bio-catalyse, et procede de traitement correspondant, applicables notamment a la transformation malolactique du vin.
US5434079A (en) * 1993-02-12 1995-07-18 The United States Of America As Represented By The Department Of Health And Human Services Apparatus and process for continuous in vitro synthesis of proteins
US5599688A (en) * 1993-10-18 1997-02-04 Precision Instrument Design Device and method for circulating fluid over a membrane
US5591636A (en) * 1993-10-18 1997-01-07 Precision Instrument Design Membrane holder
US5688687A (en) * 1995-06-07 1997-11-18 Aastrom Biosciences, Inc. Bioreactor for mammalian cell growth and maintenance
EP0894852B1 (de) * 1997-07-31 2004-01-28 Roche Diagnostics GmbH Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen

Also Published As

Publication number Publication date
US6670173B1 (en) 2003-12-30
EP1144587A1 (de) 2001-10-17
DE10080164D2 (de) 2001-12-13
JP2002538778A (ja) 2002-11-19
WO2000044877A1 (de) 2000-08-03
CA2360077A1 (en) 2000-08-03
EP1144587B1 (de) 2003-07-23
ATE245693T1 (de) 2003-08-15

Similar Documents

Publication Publication Date Title
ATE245693T1 (de) Vorrichtung zum zellfreie synthese von proteine
FR2772789B1 (fr) Procede de preparation enzymatique d'homogentisate
ATE66072T1 (de) Quantitatives analysesystem ohne instrumente.
PT990047E (pt) Metodos e composicoes para a analise de acidos nucleicos por espectroscopia de massa.
DK0859848T3 (da) Fremgangsmåde til fremstilling af D-pantoinsyre og D-pantothensyre eller salte deraf
DK0832097T3 (da) System og fremgangsmåde til modifikation og rensning af peptider
TR200200757T2 (tr) Hücrelerin proteinsiz veya serumsuz yerleştirilmesi için ortam
GB9907813D0 (en) Synthesis
DE69833450D1 (de) Sensor zur erfassung von biologischem komplex
DK0785986T3 (da) Fremgangsmåde til fremstilling af hydrofobe produkter og dertil egnet indretning
ATE272436T1 (de) Mikrofiltration unter verwendung von aktivkohle
DK0701603T3 (da) Antiskumindretning til en bioreaktor
AU2001289614A1 (en) Microreactor device for solid-phase supported synthesis and microreactor system comprising individual microreactor devices
JPH11127889A5 (https=)
AU2003210413A1 (en) Device for applying liquid media and corresponding method
ATE322336T1 (de) Kit zur durchführung biochemischer reaktionen mit hohem durchsatz
DK1049794T3 (da) Fremgangsmåde til fremstilling af L-carnitin af crotonobetain
IT1216083B (it) Dispositivo perfezionato perl'esecuzione di esami microbiologici colturali.
DK0999997T3 (da) Fremgangsmåde til affarvning af væsker
IS5469A (is) Aðferð til efnasmíða á pýrról amíðum
DK0730412T3 (da) Fremgangsmåde til fremstilling af proteiner ud fra et proteinholdigt stof
TR200000150T2 (tr) Amidlerin elde edilmesine mahsus usul.
DK0924195T3 (da) Fremgangsmåde til fremstilling af aminocyanacetamid
DE59804958D1 (de) Anordnung zur Freisetzung von Reagenzien
DE69722852D1 (de) Fermentative Herstellung von Biotin

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee