JP2002536413A - 末梢ニューロパシーの治療における4−アミノピリジンの使用 - Google Patents

末梢ニューロパシーの治療における4−アミノピリジンの使用

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Publication number
JP2002536413A
JP2002536413A JP2000598162A JP2000598162A JP2002536413A JP 2002536413 A JP2002536413 A JP 2002536413A JP 2000598162 A JP2000598162 A JP 2000598162A JP 2000598162 A JP2000598162 A JP 2000598162A JP 2002536413 A JP2002536413 A JP 2002536413A
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JP
Japan
Prior art keywords
aminopyridine
nervous system
peripheral nervous
subject
compound
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000598162A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002536413A5 (https=
Inventor
ジェイ エム メイサラー
Original Assignee
ユーエイビー リサーチ ファンデーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユーエイビー リサーチ ファンデーション filed Critical ユーエイビー リサーチ ファンデーション
Publication of JP2002536413A publication Critical patent/JP2002536413A/ja
Publication of JP2002536413A5 publication Critical patent/JP2002536413A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP2000598162A 1999-02-09 2000-02-09 末梢ニューロパシーの治療における4−アミノピリジンの使用 Pending JP2002536413A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11927399P 1999-02-09 1999-02-09
US60/119,273 1999-02-09
PCT/US2000/003396 WO2000047210A1 (en) 1999-02-09 2000-02-09 Use of 4-amino pyridine for treatment of peripheral neuropathies

Publications (2)

Publication Number Publication Date
JP2002536413A true JP2002536413A (ja) 2002-10-29
JP2002536413A5 JP2002536413A5 (https=) 2007-04-05

Family

ID=22383494

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000598162A Pending JP2002536413A (ja) 1999-02-09 2000-02-09 末梢ニューロパシーの治療における4−アミノピリジンの使用

Country Status (10)

Country Link
US (1) US6503931B1 (https=)
EP (1) EP1152760B1 (https=)
JP (1) JP2002536413A (https=)
AT (1) ATE357914T1 (https=)
AU (1) AU3360000A (https=)
CA (1) CA2360326C (https=)
DE (1) DE60034110T2 (https=)
DK (1) DK1152760T3 (https=)
ES (1) ES2284485T3 (https=)
WO (1) WO2000047210A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2820423B1 (fr) * 2001-02-05 2005-12-02 Assist Publ Hopitaux De Paris Tartrate et phosphate de 3,4-diaminopyridine, compositions pharmaceutiques et utilisations
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
US10793893B2 (en) 2011-06-30 2020-10-06 Serb Sa Methods of administering 3,4-diaminopyridine
TWI592156B (zh) * 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法
WO2014151752A1 (en) 2013-03-15 2014-09-25 University Of Rochester Composition and methods for the treatment of peripheral nerve injury
MA35698B1 (fr) * 2013-05-16 2014-12-01 Univ Mohammed V Souissi Nouvelle composition du 3,4-diaminopyridin pour le traitement de la fatigabilité musculaire associée à des troubles neurovégétatifs.
WO2024011220A1 (en) 2022-07-08 2024-01-11 University Of Rochester Potassium channel blockers or derivatives thereof for preventing, alleviating, and/or treating tissue dysfunction caused by toxic insults

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221683A (en) * 1984-03-19 1993-06-22 The Rockefeller University Diaminopyridine compounds and methods of use
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
US5668117A (en) * 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
CA2085785C (en) * 1992-12-18 2005-03-15 Robert R. Hansebout The use of 4-aminopyridine in the treatment of a neurological condition

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CSNC200900212021, 馬場 正之, "Lewis—Sumner症候群", 医学のあゆみ IGAKU NO AYUMI, 第154巻, 三浦 裕士 医歯薬出版株式会社 *
CSNC200900542017, 結城 伸泰 Nobuhiro YUUKI, "変貌を遂げたGuillain−Barre症候群の疾患概念 Changing concept of Guillain−Barre syndrom", 医学のあゆみ IGAKU NO AYUMI, 第181巻, 三浦 裕士 医歯薬出版株式会社 *
CSNC200900625071, 堀田 饒 Nigishi HOTTA, "糖尿病性神経障害の病態と治療 Pathophysiology and treatment of diabetic neuropathy", 医学のあゆみ IGAKU NO AYUMI, 第188巻, 三浦 裕士 医歯薬出版株式会社 *

Also Published As

Publication number Publication date
DE60034110T2 (de) 2007-12-06
WO2000047210A1 (en) 2000-08-17
CA2360326A1 (en) 2000-08-17
EP1152760A4 (en) 2005-03-23
US6503931B1 (en) 2003-01-07
ATE357914T1 (de) 2007-04-15
DE60034110D1 (de) 2007-05-10
CA2360326C (en) 2011-04-05
EP1152760B1 (en) 2007-03-28
AU3360000A (en) 2000-08-29
DK1152760T3 (da) 2007-07-30
EP1152760A1 (en) 2001-11-14
ES2284485T3 (es) 2007-11-16

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