JP2002535994A5 - - Google Patents
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- Publication number
- JP2002535994A5 JP2002535994A5 JP2000597444A JP2000597444A JP2002535994A5 JP 2002535994 A5 JP2002535994 A5 JP 2002535994A5 JP 2000597444 A JP2000597444 A JP 2000597444A JP 2000597444 A JP2000597444 A JP 2000597444A JP 2002535994 A5 JP2002535994 A5 JP 2002535994A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- vector
- restriction endonuclease
- target
- introducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091008146 restriction endonucleases Proteins 0.000 description 41
- 239000013598 vector Substances 0.000 description 41
- 238000000034 method Methods 0.000 description 22
- 239000013611 chromosomal DNA Substances 0.000 description 20
- 108090000623 proteins and genes Proteins 0.000 description 12
- 108020004707 nucleic acids Proteins 0.000 description 9
- 150000007523 nucleic acids Chemical class 0.000 description 9
- 102000039446 nucleic acids Human genes 0.000 description 9
- 230000006798 recombination Effects 0.000 description 9
- 238000005215 recombination Methods 0.000 description 9
- 230000035772 mutation Effects 0.000 description 5
- 230000008439 repair process Effects 0.000 description 4
- 238000013518 transcription Methods 0.000 description 3
- 230000035897 transcription Effects 0.000 description 3
- 239000013603 viral vector Substances 0.000 description 3
- 241000700605 Viruses Species 0.000 description 2
- 239000013612 plasmid Substances 0.000 description 2
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000002715 modification method Methods 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11847299P | 1999-02-03 | 1999-02-03 | |
| US60/118,472 | 1999-02-03 | ||
| PCT/US2000/002949 WO2000046385A1 (en) | 1999-02-03 | 2000-02-03 | Gene repair involving in vivo excision of targeting dna |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002535994A JP2002535994A (ja) | 2002-10-29 |
| JP2002535994A5 true JP2002535994A5 (https=) | 2007-04-05 |
Family
ID=22378818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000597444A Pending JP2002535994A (ja) | 1999-02-03 | 2000-02-03 | 標的ｄｎａのインビボ除去による遺伝子修復 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20020110898A1 (https=) |
| EP (1) | EP1151124A1 (https=) |
| JP (1) | JP2002535994A (https=) |
| AU (1) | AU2982300A (https=) |
| CA (1) | CA2360878A1 (https=) |
| WO (1) | WO2000046385A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7102055B1 (en) * | 1997-11-18 | 2006-09-05 | Pioneer Hi-Bred International, Inc. | Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant |
| US6187994B1 (en) * | 1997-11-18 | 2001-02-13 | Pioneer Hi-Bred International, Inc. | Compositions and methods for genetic modification of plants |
| JP2002535994A (ja) * | 1999-02-03 | 2002-10-29 | ザ チルドレンズ メディカル センター コーポレイション | 標的ｄｎａのインビボ除去による遺伝子修復 |
| WO2000046386A2 (en) | 1999-02-03 | 2000-08-10 | The Children's Medical Center Corporation | Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site |
| AU2002339224B2 (en) | 2001-09-14 | 2008-10-09 | Kuros Us Llc | Packaging of immunostimulatory substances into virus-like particles: method of preparation and use |
| EP1476547B1 (en) | 2002-01-23 | 2006-12-06 | The University of Utah Research Foundation | Targeted chromosomal mutagenesis using zinc finger nucleases |
| US20060078552A1 (en) | 2002-03-15 | 2006-04-13 | Sylvain Arnould | Hybrid and single chain meganucleases and use thereof |
| WO2009095742A1 (en) | 2008-01-31 | 2009-08-06 | Cellectis | New i-crei derived single-chain meganuclease and uses thereof |
| US20030232410A1 (en) * | 2002-03-21 | 2003-12-18 | Monika Liljedahl | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| EP2806025B1 (en) | 2002-09-05 | 2019-04-03 | California Institute of Technology | Use of zinc finger nucleases to stimulate gene targeting |
| US20060153826A1 (en) | 2003-01-28 | 2006-07-13 | Sylvain Arnould | Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof |
| US11311574B2 (en) | 2003-08-08 | 2022-04-26 | Sangamo Therapeutics, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US20120196370A1 (en) | 2010-12-03 | 2012-08-02 | Fyodor Urnov | Methods and compositions for targeted genomic deletion |
| US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| BRPI0612862A2 (pt) * | 2005-07-18 | 2010-11-30 | Pioneer Hi Bred Int | polinucleotìdeo isolado, método para obtenção de uma célula transformada, método para obtenção de uma planta transformada, método de produção de recombinação de dna de sìtio especìfico, biblioteca isolada, método de geração de biblioteca de moléculas e método para selecionar sìtio de recombinação frt modificado |
| CA2891996A1 (en) | 2005-10-18 | 2007-04-26 | Duke University | Rationally-designed meganucleases with altered sequence specificity and dna-binding affinity |
| US7852247B2 (en) * | 2006-12-05 | 2010-12-14 | Texas Instruments Incorporated | Mixed-signal filter |
| CN101849010A (zh) * | 2007-06-29 | 2010-09-29 | 先锋高级育种国际公司 | 用于改变单子叶植物细胞的基因组的方法 |
| EP2215252A4 (en) * | 2007-12-07 | 2011-01-26 | Prec Biosciences Inc | RATIONAL-DESIGNED MEGANUCLEASES WITH DETECTION SEQUENCES FROM DNASE-HYPERSENSITIVE REGIONS OF THE HUMAN GENOME |
| WO2009114321A2 (en) * | 2008-03-11 | 2009-09-17 | Precision Biosciencs, Inc. | Rationally-designed meganucleases for maize genome engineering |
| US20100071083A1 (en) * | 2008-03-12 | 2010-03-18 | Smith James J | Temperature-dependent meganuclease activity |
| EP2279250A4 (en) * | 2008-04-28 | 2011-10-12 | Prec Biosciences Inc | Fusion Molecules of DNA Binding Proteins with Rational Design and Effects Domain |
| DK3211075T3 (en) | 2008-07-14 | 2019-01-21 | Prec Biosciences Inc | RECOGNITION SEQUENCES FOR I-CREI-DERIVED MECHANUCLEASES AND APPLICATIONS THEREOF |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US285538A (en) * | 1883-09-25 | Ore-crusher | ||
| US5436150A (en) | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5792632A (en) * | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| US5474896A (en) | 1992-05-05 | 1995-12-12 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| ES2132330T3 (es) | 1993-12-20 | 1999-08-16 | Akzo Nobel Nv | Vacuna para la proteccion de caballos frente a la infeccion por el virus del herpes equino. |
| US5830729A (en) * | 1996-04-18 | 1998-11-03 | Institut Pasteur | I Sce I-induced gene replacement and gene conversion in embryonic stem cells |
| WO2000046386A2 (en) | 1999-02-03 | 2000-08-10 | The Children's Medical Center Corporation | Gene repair involving the induction of double-stranded dna cleavage at a chromosomal target site |
| JP2002535994A (ja) | 1999-02-03 | 2002-10-29 | ザ チルドレンズ メディカル センター コーポレイション | 標的ｄｎａのインビボ除去による遺伝子修復 |
| ATE466088T1 (de) * | 2001-09-14 | 2010-05-15 | Cellectis | Zufällige integration von polynukleotide nach in vivo linearisierung |
| JP3915752B2 (ja) * | 2003-07-25 | 2007-05-16 | 船井電機株式会社 | デジタル情報記録装置およびそれを備える映像記録再生装置 |
-
2000
- 2000-02-03 JP JP2000597444A patent/JP2002535994A/ja active Pending
- 2000-02-03 EP EP00908491A patent/EP1151124A1/en not_active Ceased
- 2000-02-03 WO PCT/US2000/002949 patent/WO2000046385A1/en not_active Ceased
- 2000-02-03 CA CA002360878A patent/CA2360878A1/en not_active Abandoned
- 2000-02-03 AU AU29823/00A patent/AU2982300A/en not_active Abandoned
-
2001
- 2001-08-03 US US09/922,495 patent/US20020110898A1/en not_active Abandoned
-
2003
- 2003-01-02 US US10/336,069 patent/US7285538B2/en not_active Expired - Lifetime
-
2007
- 2007-09-25 US US11/904,034 patent/US7960525B2/en not_active Expired - Fee Related
-
2011
- 2011-05-05 US US13/101,463 patent/US20120165400A1/en not_active Abandoned
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