JP2002523094A - アタキシン−２結合タンパク質をコードする核酸、それらに関する産物、およびそれらを使用する方法 - Google Patents
アタキシン−２結合タンパク質をコードする核酸、それらに関する産物、およびそれらを使用する方法Info
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/145,391 | 1998-09-01 | ||
| US09/145,391 US6194171B1 (en) | 1998-09-01 | 1998-09-01 | Nucleic acids encoding ataxin-2 binding proteins |
| PCT/US1999/020156 WO2000012710A1 (en) | 1998-09-01 | 1999-09-01 | Nucleic acids encoding ataxin-2 binding proteins, products related thereto and methods of using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002523094A true JP2002523094A (ja) | 2002-07-30 |
| JP2002523094A5 JP2002523094A5 (enExample) | 2006-10-12 |
Family
ID=22512899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000567697A Pending JP2002523094A (ja) | 1998-09-01 | 1999-09-01 | アタキシン−２結合タンパク質をコードする核酸、それらに関する産物、およびそれらを使用する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US6194171B1 (enExample) |
| EP (1) | EP1108026B1 (enExample) |
| JP (1) | JP2002523094A (enExample) |
| DE (1) | DE69924120T2 (enExample) |
| WO (1) | WO2000012710A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6515197B1 (en) | 2000-08-24 | 2003-02-04 | Cedars-Sinai Medical Center | Transgenic mouse expressing a polynucleotide encoding a human ataxin-2 polypeptide |
| US7446239B2 (en) * | 2001-05-07 | 2008-11-04 | Cedars-Sinai Medical Center | SCA2 knockout animal and methods of use |
| US20020166924A1 (en) * | 2001-05-08 | 2002-11-14 | Wm. David Fahey | Methods and apparatus for canopy fragilization |
| US20040214166A1 (en) * | 2001-06-08 | 2004-10-28 | Xianqiang Li | Method for identifying a disease state based on a detected mixture of activated transcription factors |
| US6696256B1 (en) * | 2001-06-08 | 2004-02-24 | Pandmics, Inc. | Method, array and kit for detecting activated transcription factors by hybridization array |
| US7981842B2 (en) | 2001-06-08 | 2011-07-19 | Panomics, Inc. | Method for detecting transcription factor-protein interactions |
| US6924113B2 (en) | 2001-06-08 | 2005-08-02 | Panomics, Inc. | Method and kit for isolating DNA probes that bind to activated transcription factors |
| US6821737B2 (en) | 2001-06-08 | 2004-11-23 | Panomics, Inc. | Method for screening for drug candidates for modulating transcription factor activity |
| JP7379387B2 (ja) | 2018-06-05 | 2023-11-14 | エフ． ホフマン－ラ ロシュ アーゲー | Ａｔｘｎ２発現を制御するためのオリゴヌクレオチド |
| US11286485B2 (en) | 2019-04-04 | 2022-03-29 | Hoffmann-La Roche Inc. | Oligonucleotides for modulating ATXN2 expression |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5714594A (en) | 1994-10-18 | 1998-02-03 | Mayo Foundation For Medical Education And Research | cDNA cloning and expression of human liver estrogen sulfotransferase |
| WO1997042314A1 (en) | 1996-05-08 | 1997-11-13 | Cedars-Sinai Medical Center | Nucleic acid encoding spinocerebellar ataxia-2 and products related thereto |
-
1998
- 1998-09-01 US US09/145,391 patent/US6194171B1/en not_active Expired - Lifetime
-
1999
- 1999-09-01 WO PCT/US1999/020156 patent/WO2000012710A1/en not_active Ceased
- 1999-09-01 EP EP99946729A patent/EP1108026B1/en not_active Expired - Lifetime
- 1999-09-01 JP JP2000567697A patent/JP2002523094A/ja active Pending
- 1999-09-01 DE DE69924120T patent/DE69924120T2/de not_active Expired - Fee Related
-
2001
- 2001-02-26 US US09/794,591 patent/US6617430B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1108026A1 (en) | 2001-06-20 |
| WO2000012710A1 (en) | 2000-03-09 |
| DE69924120D1 (de) | 2005-04-14 |
| WO2000012710A8 (en) | 2000-05-11 |
| EP1108026B1 (en) | 2005-03-09 |
| US20010018198A1 (en) | 2001-08-30 |
| US6617430B2 (en) | 2003-09-09 |
| DE69924120T2 (de) | 2006-04-13 |
| US6194171B1 (en) | 2001-02-27 |
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