JP2002523044A - 血液を形成する造血幹細胞を調節する遺伝子およびその使用 - Google Patents

血液を形成する造血幹細胞を調節する遺伝子およびその使用

Info

Publication number
JP2002523044A
JP2002523044A JP2000566422A JP2000566422A JP2002523044A JP 2002523044 A JP2002523044 A JP 2002523044A JP 2000566422 A JP2000566422 A JP 2000566422A JP 2000566422 A JP2000566422 A JP 2000566422A JP 2002523044 A JP2002523044 A JP 2002523044A
Authority
JP
Japan
Prior art keywords
cells
cell
stem
seq
dlk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000566422A
Other languages
English (en)
Japanese (ja)
Inventor
イホール レミシュカ
カテリ ムーア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Princeton University
Original Assignee
Princeton University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Princeton University filed Critical Princeton University
Publication of JP2002523044A publication Critical patent/JP2002523044A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2000566422A 1998-08-21 1999-08-20 血液を形成する造血幹細胞を調節する遺伝子およびその使用 Pending JP2002523044A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13813298A 1998-08-21 1998-08-21
US09/138,132 1998-08-21
PCT/US1999/019052 WO2000011168A2 (fr) 1998-08-21 1999-08-20 Genes regulant les cellules souche hematopoietiques et utilisation de ces genes

Publications (1)

Publication Number Publication Date
JP2002523044A true JP2002523044A (ja) 2002-07-30

Family

ID=22480559

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000566422A Pending JP2002523044A (ja) 1998-08-21 1999-08-20 血液を形成する造血幹細胞を調節する遺伝子およびその使用

Country Status (5)

Country Link
EP (1) EP1105482A2 (fr)
JP (1) JP2002523044A (fr)
AU (1) AU5780999A (fr)
CA (1) CA2340465A1 (fr)
WO (1) WO2000011168A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094545A2 (fr) * 2000-06-02 2001-12-13 Massachusetts Institute Of Technology Chemin suppresseur de tumeurs chez $i(c. elegans)
US20020082191A1 (en) * 2000-12-08 2002-06-27 Karl Guegler Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
JP5791506B2 (ja) 2009-09-29 2015-10-07 国立大学法人九州大学 造血幹細胞または造血前駆細胞の分化を抑制するペプチド及びその用途
WO2016069925A1 (fr) * 2014-10-30 2016-05-06 Acceleron Pharma Inc. Méthodes et compositions utilisant des polypeptides gdf15 pour augmenter le nombre de globules rouges sanguins

Also Published As

Publication number Publication date
AU5780999A (en) 2000-03-14
WO2000011168A2 (fr) 2000-03-02
CA2340465A1 (fr) 2000-03-02
EP1105482A2 (fr) 2001-06-13
WO2000011168A3 (fr) 2000-06-22

Similar Documents

Publication Publication Date Title
Schessl et al. The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice
Laborde Invited Reviews-The role of the epidermal growth factor-like protein dlk in cell differentiation
CN109790213B (zh) 用于鉴定lilrb阻断抗体的方法
Krosl et al. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential
US7906331B2 (en) Methods for identifying stem cells expressing breast cancer resistance protein (BCRP)
KR20210013284A (ko) 증강된 친화성 t　세포 수용체 및 이의 제조 방법
Graham et al. Haemopoietic stem cells: their heterogeneity and regulation
US11566226B2 (en) Natural killer cells
Cuykendall et al. Vegetally localized Xenopus trim36 regulates cortical rotation and dorsal axis formation
Regunathan et al. Differential and nonredundant roles of phospholipase Cγ2 and phospholipase Cγ1 in the terminal maturation of NK cells
US20040072259A1 (en) Methods and products for manipulating hematopoietic stem cells
JP4970948B2 (ja) 癌幹細胞の同定、単離、および除去の方法
JP2001523456A (ja) 転写的に調節されたｇタンパク質−共役受容体
JP2002523044A (ja) 血液を形成する造血幹細胞を調節する遺伝子およびその使用
US20120201792A1 (en) Methods and products for manipulating hematopoietic stem cells
Dawson et al. Functional effects of chimeric antigen receptor co-receptor signaling domains in human Tregs
US20020064855A1 (en) Genes that regulate hematopoietic blood forming stem cells and uses thereof
Zhang et al. Regulation of pDC fate determination by histone deacetylase 3
US20230002732A1 (en) Natural killer cells
Casetti New roles of STAT5 factors in chronic myeloid leukemia cell maintenance
Hills Novel Regulatory Mechanisms of Foxo1-Dependent Transcription, CD8 T Cell Memory and Survival
CN117580856A (zh) 靶向次要组织相容性抗原ha-1的t细胞受体(tcr)
US20040043434A1 (en) Shp-2 tyrosine phosphatase and embryonic stem cell differentiation
CN116783284A (zh) 用于细胞重编程的组合物、构建体和载体
Garrison The characterization of the protein Pactolus and its involvement in neutrophil clearance