JP2002518102A - 組織修復方法ｉｉ - Google Patents
組織修復方法ｉｉInfo
- Publication number
- JP2002518102A JP2002518102A JP2000554413A JP2000554413A JP2002518102A JP 2002518102 A JP2002518102 A JP 2002518102A JP 2000554413 A JP2000554413 A JP 2000554413A JP 2000554413 A JP2000554413 A JP 2000554413A JP 2002518102 A JP2002518102 A JP 2002518102A
- Authority
- JP
- Japan
- Prior art keywords
- bonding agent
- tube
- tissue
- conjugate
- paragraph
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 101
- 230000017423 tissue regeneration Effects 0.000 title claims description 7
- 239000007767 bonding agent Substances 0.000 claims abstract description 170
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 67
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 67
- 239000000463 material Substances 0.000 claims abstract description 26
- 239000007787 solid Substances 0.000 claims abstract description 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 6
- 229920001184 polypeptide Polymers 0.000 claims abstract description 5
- 210000001519 tissue Anatomy 0.000 claims description 94
- 239000004568 cement Substances 0.000 claims description 56
- 239000011230 binding agent Substances 0.000 claims description 50
- 230000008439 repair process Effects 0.000 claims description 46
- 239000000203 mixture Substances 0.000 claims description 30
- 239000000835 fiber Substances 0.000 claims description 29
- 108010088751 Albumins Proteins 0.000 claims description 28
- 102000009027 Albumins Human genes 0.000 claims description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- 238000004925 denaturation Methods 0.000 claims description 26
- 230000036425 denaturation Effects 0.000 claims description 26
- 210000001367 artery Anatomy 0.000 claims description 23
- 210000004204 blood vessel Anatomy 0.000 claims description 22
- 239000011358 absorbing material Substances 0.000 claims description 20
- 238000005304 joining Methods 0.000 claims description 19
- 210000005036 nerve Anatomy 0.000 claims description 19
- 239000000975 dye Substances 0.000 claims description 18
- 239000000126 substance Substances 0.000 claims description 18
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical group [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 claims description 17
- 229960004657 indocyanine green Drugs 0.000 claims description 17
- 239000000243 solution Substances 0.000 claims description 15
- 239000002904 solvent Substances 0.000 claims description 15
- 102000008186 Collagen Human genes 0.000 claims description 14
- 239000003795 chemical substances by application Substances 0.000 claims description 14
- 229920001436 collagen Polymers 0.000 claims description 14
- 108010035532 Collagen Proteins 0.000 claims description 13
- 241000282414 Homo sapiens Species 0.000 claims description 13
- 241001465754 Metazoa Species 0.000 claims description 13
- 241000283973 Oryctolagus cuniculus Species 0.000 claims description 13
- 238000001035 drying Methods 0.000 claims description 12
- 239000003292 glue Substances 0.000 claims description 12
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims description 10
- 239000002671 adjuvant Substances 0.000 claims description 10
- 239000003125 aqueous solvent Substances 0.000 claims description 10
- 210000004369 blood Anatomy 0.000 claims description 10
- 239000008280 blood Substances 0.000 claims description 10
- 230000006378 damage Effects 0.000 claims description 10
- 239000002657 fibrous material Substances 0.000 claims description 10
- 210000000578 peripheral nerve Anatomy 0.000 claims description 10
- 230000001954 sterilising effect Effects 0.000 claims description 10
- 230000000694 effects Effects 0.000 claims description 9
- 239000000853 adhesive Substances 0.000 claims description 8
- 230000001070 adhesive effect Effects 0.000 claims description 8
- 238000000576 coating method Methods 0.000 claims description 8
- 230000021615 conjugation Effects 0.000 claims description 8
- 108091006905 Human Serum Albumin Proteins 0.000 claims description 7
- 241000700159 Rattus Species 0.000 claims description 7
- 229940098773 bovine serum albumin Drugs 0.000 claims description 7
- 230000035876 healing Effects 0.000 claims description 7
- 238000011282 treatment Methods 0.000 claims description 7
- 102000008946 Fibrinogen Human genes 0.000 claims description 6
- 108010049003 Fibrinogen Proteins 0.000 claims description 6
- 241001494479 Pecora Species 0.000 claims description 6
- 230000015572 biosynthetic process Effects 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 6
- 230000001268 conjugating effect Effects 0.000 claims description 6
- 238000000151 deposition Methods 0.000 claims description 6
- 230000008021 deposition Effects 0.000 claims description 6
- 229940012952 fibrinogen Drugs 0.000 claims description 6
- 210000000056 organ Anatomy 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 230000002792 vascular Effects 0.000 claims description 6
- 102000008100 Human Serum Albumin Human genes 0.000 claims description 5
- 101000930455 Ovis aries Albumin Proteins 0.000 claims description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 5
- 239000003146 anticoagulant agent Substances 0.000 claims description 5
- 239000001046 green dye Substances 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 239000005556 hormone Substances 0.000 claims description 5
- 229940088597 hormone Drugs 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 230000004048 modification Effects 0.000 claims description 5
- 238000012986 modification Methods 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 5
- -1 polytetrafluoroethylene Polymers 0.000 claims description 5
- 241000283690 Bos taurus Species 0.000 claims description 4
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 4
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 238000007792 addition Methods 0.000 claims description 4
- 229940127219 anticoagulant drug Drugs 0.000 claims description 4
- 229920000249 biocompatible polymer Polymers 0.000 claims description 4
- 210000004556 brain Anatomy 0.000 claims description 4
- 239000000919 ceramic Substances 0.000 claims description 4
- 238000001125 extrusion Methods 0.000 claims description 4
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000003102 growth factor Substances 0.000 claims description 4
- 229920000669 heparin Polymers 0.000 claims description 4
- 229960002897 heparin Drugs 0.000 claims description 4
- 238000001727 in vivo Methods 0.000 claims description 4
- 238000003780 insertion Methods 0.000 claims description 4
- 230000037431 insertion Effects 0.000 claims description 4
- 210000001640 nerve ending Anatomy 0.000 claims description 4
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 4
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 4
- 230000008929 regeneration Effects 0.000 claims description 4
- 238000011069 regeneration method Methods 0.000 claims description 4
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 4
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 4
- 229920000544 Gore-Tex Polymers 0.000 claims description 3
- 101000930457 Rattus norvegicus Albumin Proteins 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 239000012530 fluid Substances 0.000 claims description 3
- 230000004927 fusion Effects 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims description 3
- 210000004185 liver Anatomy 0.000 claims description 3
- 239000003550 marker Substances 0.000 claims description 3
- 230000001537 neural effect Effects 0.000 claims description 3
- 230000005855 radiation Effects 0.000 claims description 3
- 210000000278 spinal cord Anatomy 0.000 claims description 3
- 238000002604 ultrasonography Methods 0.000 claims description 3
- 108010014258 Elastin Proteins 0.000 claims description 2
- 102000016942 Elastin Human genes 0.000 claims description 2
- 241000283073 Equus caballus Species 0.000 claims description 2
- 230000002411 adverse Effects 0.000 claims description 2
- 230000008878 coupling Effects 0.000 claims description 2
- 238000005520 cutting process Methods 0.000 claims description 2
- 229920002549 elastin Polymers 0.000 claims description 2
- 210000000918 epididymis Anatomy 0.000 claims description 2
- 201000010063 epididymitis Diseases 0.000 claims description 2
- 230000002496 gastric effect Effects 0.000 claims description 2
- 238000003505 heat denaturation Methods 0.000 claims description 2
- 230000028993 immune response Effects 0.000 claims description 2
- 210000003734 kidney Anatomy 0.000 claims description 2
- 239000011159 matrix material Substances 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 229960000907 methylthioninium chloride Drugs 0.000 claims description 2
- 210000004088 microvessel Anatomy 0.000 claims description 2
- 210000003101 oviduct Anatomy 0.000 claims description 2
- 239000004033 plastic Substances 0.000 claims description 2
- 229920003023 plastic Polymers 0.000 claims description 2
- 210000002307 prostate Anatomy 0.000 claims description 2
- 230000000241 respiratory effect Effects 0.000 claims description 2
- 238000007789 sealing Methods 0.000 claims description 2
- 210000000952 spleen Anatomy 0.000 claims description 2
- 229910001220 stainless steel Inorganic materials 0.000 claims description 2
- 239000010935 stainless steel Substances 0.000 claims description 2
- 229920002994 synthetic fiber Polymers 0.000 claims description 2
- 239000012209 synthetic fiber Substances 0.000 claims description 2
- 210000001550 testis Anatomy 0.000 claims description 2
- 230000000451 tissue damage Effects 0.000 claims description 2
- 231100000827 tissue damage Toxicity 0.000 claims description 2
- 210000003708 urethra Anatomy 0.000 claims description 2
- 210000003932 urinary bladder Anatomy 0.000 claims description 2
- 210000004291 uterus Anatomy 0.000 claims description 2
- 239000003351 stiffener Substances 0.000 claims 4
- 210000000232 gallbladder Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical group C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 238000004026 adhesive bonding Methods 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 150000004679 hydroxides Chemical class 0.000 claims 1
- 238000001746 injection moulding Methods 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 230000001788 irregular Effects 0.000 claims 1
- 210000002751 lymph Anatomy 0.000 claims 1
- 230000007514 neuronal growth Effects 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 239000008247 solid mixture Substances 0.000 claims 1
- 210000000626 ureter Anatomy 0.000 claims 1
- 230000003872 anastomosis Effects 0.000 description 45
- 238000003466 welding Methods 0.000 description 18
- 210000003050 axon Anatomy 0.000 description 11
- 238000001356 surgical procedure Methods 0.000 description 11
- 239000007788 liquid Substances 0.000 description 10
- 238000002360 preparation method Methods 0.000 description 8
- 230000006870 function Effects 0.000 description 7
- 238000010521 absorption reaction Methods 0.000 description 6
- 210000000709 aorta Anatomy 0.000 description 6
- 230000008859 change Effects 0.000 description 6
- 208000005422 Foreign-Body reaction Diseases 0.000 description 5
- 210000002808 connective tissue Anatomy 0.000 description 5
- 239000007943 implant Substances 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 231100000241 scar Toxicity 0.000 description 4
- 230000037390 scarring Effects 0.000 description 4
- 238000010025 steaming Methods 0.000 description 4
- 239000003356 suture material Substances 0.000 description 4
- 238000000692 Student's t-test Methods 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000012620 biological material Substances 0.000 description 3
- 230000035602 clotting Effects 0.000 description 3
- 238000012937 correction Methods 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- BCQZXOMGPXTTIC-UHFFFAOYSA-N halothane Chemical compound FC(F)(F)C(Cl)Br BCQZXOMGPXTTIC-UHFFFAOYSA-N 0.000 description 3
- 229960003132 halothane Drugs 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 210000004379 membrane Anatomy 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 230000002093 peripheral effect Effects 0.000 description 3
- 230000002787 reinforcement Effects 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 206010002091 Anaesthesia Diseases 0.000 description 2
- 208000032544 Cicatrix Diseases 0.000 description 2
- 101710118178 Protein Tube Proteins 0.000 description 2
- 108010071390 Serum Albumin Proteins 0.000 description 2
- 102000007562 Serum Albumin Human genes 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000001493 electron microscopy Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000003176 fibrotic effect Effects 0.000 description 2
- 238000013532 laser treatment Methods 0.000 description 2
- QYSGYZVSCZSLHT-UHFFFAOYSA-N octafluoropropane Chemical compound FC(F)(F)C(F)(F)C(F)(F)F QYSGYZVSCZSLHT-UHFFFAOYSA-N 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000007788 roughening Methods 0.000 description 2
- 238000004626 scanning electron microscopy Methods 0.000 description 2
- 230000037387 scars Effects 0.000 description 2
- 210000004116 schwann cell Anatomy 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 229950003937 tolonium Drugs 0.000 description 2
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 230000003313 weakening effect Effects 0.000 description 2
- 206010002329 Aneurysm Diseases 0.000 description 1
- 206010003178 Arterial thrombosis Diseases 0.000 description 1
- 102100026189 Beta-galactosidase Human genes 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 102100027207 CD27 antigen Human genes 0.000 description 1
- 206010011732 Cyst Diseases 0.000 description 1
- 206010014513 Embolism arterial Diseases 0.000 description 1
- 101000693911 Equus caballus Albumin Proteins 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 101000914511 Homo sapiens CD27 antigen Proteins 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical group [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 206010028851 Necrosis Diseases 0.000 description 1
- 208000005890 Neuroma Diseases 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 101100219325 Phaseolus vulgaris BA13 gene Proteins 0.000 description 1
- 241000700157 Rattus norvegicus Species 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000003881 arterial anastomosis Effects 0.000 description 1
- 230000004219 arterial function Effects 0.000 description 1
- 230000003376 axonal effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000006664 bond formation reaction Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000000349 chromosome Anatomy 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 108091011142 collagen binding proteins Proteins 0.000 description 1
- 238000000748 compression moulding Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 208000031513 cyst Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000002828 effect on organs or tissue Effects 0.000 description 1
- 108010064033 elastin-binding proteins Proteins 0.000 description 1
- 210000004955 epithelial membrane Anatomy 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000012212 insulator Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 238000002350 laparotomy Methods 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 1
- 238000001000 micrograph Methods 0.000 description 1
- 238000007431 microscopic evaluation Methods 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 210000000651 myofibroblast Anatomy 0.000 description 1
- 230000007511 neuronal proliferation Effects 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 210000004303 peritoneum Anatomy 0.000 description 1
- 210000001539 phagocyte Anatomy 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000008263 repair mechanism Effects 0.000 description 1
- 230000010410 reperfusion Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical group [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 238000002207 thermal evaporation Methods 0.000 description 1
- 230000009772 tissue formation Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 210000004026 tunica intima Anatomy 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000001177 vas deferen Anatomy 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000003021 water soluble solvent Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
- A61B17/1128—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis of nerves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
- A61B2017/00513—Tissue soldering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
- A61B2017/00513—Tissue soldering
- A61B2017/00517—Tissue soldering using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
- A61B2017/1107—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis for blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30451—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/848—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
- A61F2002/8486—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs provided on at least one of the ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0058—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU4214 | 1995-07-18 | ||
| AUPP4214A AUPP421498A0 (en) | 1998-06-18 | 1998-06-18 | Method of tissue repair |
| PCT/AU1999/000495 WO1999065536A1 (en) | 1998-06-18 | 1999-06-18 | Method of tissue repair ii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002518102A true JP2002518102A (ja) | 2002-06-25 |
| JP2002518102A5 JP2002518102A5 (https=) | 2006-01-05 |
Family
ID=3808460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000554413A Pending JP2002518102A (ja) | 1998-06-18 | 1999-06-18 | 組織修復方法ｉｉ |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7078378B1 (https=) |
| EP (1) | EP1087795A4 (https=) |
| JP (1) | JP2002518102A (https=) |
| CN (2) | CN1935269A (https=) |
| AU (1) | AUPP421498A0 (https=) |
| CA (1) | CA2335323A1 (https=) |
| HK (1) | HK1040939B (https=) |
| IL (2) | IL140368A0 (https=) |
| MX (1) | MXPA00012716A (https=) |
| NZ (1) | NZ509099A (https=) |
| WO (1) | WO1999065536A1 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009099253A1 (ja) * | 2008-02-07 | 2009-08-13 | Riken | 可視光硬化型接着剤 |
| JP2013510186A (ja) * | 2009-11-09 | 2013-03-21 | クルアスパンヌ | 金ナノ粒子と血清アルブミンおよび／またはコラーゲンとを含有するレーザー組織接合のための水性組成物 |
| JP2015061604A (ja) * | 2009-03-10 | 2015-04-02 | ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ | 生物学的組織結合及び修復装置及びその使用方法 |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8215314B2 (en) * | 2000-02-11 | 2012-07-10 | The General Hospital Corporation | Photochemical tissue bonding |
| US7073510B2 (en) | 2000-02-11 | 2006-07-11 | The General Hospital Corporation | Photochemical tissue bonding |
| US7147647B2 (en) | 2002-04-26 | 2006-12-12 | Medtronic, Inc. | Sintered titanium tube for the management of spinal cord injury |
| US7846141B2 (en) | 2002-09-03 | 2010-12-07 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| GB0224986D0 (en) | 2002-10-28 | 2002-12-04 | Smith & Nephew | Apparatus |
| WO2005037108A2 (en) * | 2003-10-21 | 2005-04-28 | Ramot At Tel Aviv University Ltd. | Compositions and devices including same useful for anastomosis |
| WO2005048880A2 (de) * | 2003-11-18 | 2005-06-02 | Medizinische Universität Wien | Gefässprothese |
| WO2005074817A1 (en) * | 2004-02-09 | 2005-08-18 | Avastra Ltd | Instruments for sutureless surgical technique |
| US7909805B2 (en) | 2004-04-05 | 2011-03-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| US10058642B2 (en) | 2004-04-05 | 2018-08-28 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| US8062272B2 (en) | 2004-05-21 | 2011-11-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| GB0409446D0 (en) | 2004-04-28 | 2004-06-02 | Smith & Nephew | Apparatus |
| US9079762B2 (en) | 2006-09-22 | 2015-07-14 | Ethicon Endo-Surgery, Inc. | Micro-electromechanical device |
| US20080078411A1 (en) * | 2006-10-03 | 2008-04-03 | Restore Medical, Inc. | Tongue implant for sleep apnea |
| US20080078412A1 (en) * | 2006-10-03 | 2008-04-03 | Restore Medical, Inc. | Tongue implant |
| US7561317B2 (en) | 2006-11-03 | 2009-07-14 | Ethicon Endo-Surgery, Inc. | Resonant Fourier scanning |
| US7914552B2 (en) * | 2006-11-09 | 2011-03-29 | Ethicon Endo-Surgery, Inc. | Method of performing an end-to-end anastomosis using a stent and an adhesive |
| WO2008065464A2 (en) * | 2006-11-28 | 2008-06-05 | Universita' Degli Studi Di Padova | A method for the pulmonary aerostasis and a device for its application |
| US7713265B2 (en) | 2006-12-22 | 2010-05-11 | Ethicon Endo-Surgery, Inc. | Apparatus and method for medically treating a tattoo |
| US8273015B2 (en) | 2007-01-09 | 2012-09-25 | Ethicon Endo-Surgery, Inc. | Methods for imaging the anatomy with an anatomically secured scanner assembly |
| US8801606B2 (en) | 2007-01-09 | 2014-08-12 | Ethicon Endo-Surgery, Inc. | Method of in vivo monitoring using an imaging system including scanned beam imaging unit |
| US7589316B2 (en) | 2007-01-18 | 2009-09-15 | Ethicon Endo-Surgery, Inc. | Scanning beam imaging with adjustable detector sensitivity or gain |
| US8216214B2 (en) | 2007-03-12 | 2012-07-10 | Ethicon Endo-Surgery, Inc. | Power modulation of a scanning beam for imaging, therapy, and/or diagnosis |
| US8626271B2 (en) | 2007-04-13 | 2014-01-07 | Ethicon Endo-Surgery, Inc. | System and method using fluorescence to examine within a patient's anatomy |
| US7995045B2 (en) | 2007-04-13 | 2011-08-09 | Ethicon Endo-Surgery, Inc. | Combined SBI and conventional image processor |
| WO2008143955A2 (en) * | 2007-05-14 | 2008-11-27 | The Regents Of The University Of Colorado | Laser fusion of tissue layers |
| US8160678B2 (en) | 2007-06-18 | 2012-04-17 | Ethicon Endo-Surgery, Inc. | Methods and devices for repairing damaged or diseased tissue using a scanning beam assembly |
| US20100174300A1 (en) * | 2007-06-22 | 2010-07-08 | Phillip Nicolas Blondeel | Sutureless vessel anastomosis method and apparatus |
| US20080319461A1 (en) * | 2007-06-22 | 2008-12-25 | Ghent University | Sutureless vessel anastomosis method and apparatus |
| US7982776B2 (en) | 2007-07-13 | 2011-07-19 | Ethicon Endo-Surgery, Inc. | SBI motion artifact removal apparatus and method |
| US9125552B2 (en) | 2007-07-31 | 2015-09-08 | Ethicon Endo-Surgery, Inc. | Optical scanning module and means for attaching the module to medical instruments for introducing the module into the anatomy |
| US7983739B2 (en) | 2007-08-27 | 2011-07-19 | Ethicon Endo-Surgery, Inc. | Position tracking and control for a scanning assembly |
| US7925333B2 (en) | 2007-08-28 | 2011-04-12 | Ethicon Endo-Surgery, Inc. | Medical device including scanned beam unit with operational control features |
| EP2987510B1 (en) | 2007-11-21 | 2020-10-28 | T.J. Smith & Nephew Limited | Suction device and dressing |
| GB0722820D0 (en) | 2007-11-21 | 2008-01-02 | Smith & Nephew | Vacuum assisted wound dressing |
| HUE043133T2 (hu) | 2007-11-21 | 2019-07-29 | Smith & Nephew | Sebkötözés |
| US20130096518A1 (en) | 2007-12-06 | 2013-04-18 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| US11253399B2 (en) | 2007-12-06 | 2022-02-22 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| GB0723875D0 (en) | 2007-12-06 | 2008-01-16 | Smith & Nephew | Wound management |
| GB0803564D0 (en) | 2008-02-27 | 2008-04-02 | Smith & Nephew | Fluid collection |
| US8050520B2 (en) | 2008-03-27 | 2011-11-01 | Ethicon Endo-Surgery, Inc. | Method for creating a pixel image from sampled data of a scanned beam imager |
| US8332014B2 (en) | 2008-04-25 | 2012-12-11 | Ethicon Endo-Surgery, Inc. | Scanned beam device and method using same which measures the reflectance of patient tissue |
| CN102238971A (zh) * | 2008-09-19 | 2011-11-09 | 宾夕法尼亚大学董事会 | 焊接制剂及其在组织焊接中的应用 |
| GB0902816D0 (en) | 2009-02-19 | 2009-04-08 | Smith & Nephew | Fluid communication path |
| US9433700B2 (en) | 2009-04-27 | 2016-09-06 | Medibeacon Inc. | Tissue sealant compositions, vascular closure devices, and uses thereof |
| US9061095B2 (en) | 2010-04-27 | 2015-06-23 | Smith & Nephew Plc | Wound dressing and method of use |
| GB201011173D0 (en) | 2010-07-02 | 2010-08-18 | Smith & Nephew | Provision of wound filler |
| GB201020005D0 (en) | 2010-11-25 | 2011-01-12 | Smith & Nephew | Composition 1-1 |
| EP2643412B1 (en) | 2010-11-25 | 2016-08-17 | Smith & Nephew PLC | Composition i-ii and products and uses thereof |
| US20150159066A1 (en) | 2011-11-25 | 2015-06-11 | Smith & Nephew Plc | Composition, apparatus, kit and method and uses thereof |
| WO2014015274A1 (en) | 2012-07-20 | 2014-01-23 | The General Hospital Corporation | Methods for tissue passivation |
| US10549112B2 (en) | 2012-07-20 | 2020-02-04 | The General Hospital Corporation | Apparatus for tissue irradiation and methods and kits utilizing the same |
| US9629997B2 (en) * | 2012-09-25 | 2017-04-25 | Axogen Corporation | Materials and methods for protecting against neuromas |
| EP2968647B1 (en) | 2013-03-15 | 2022-06-29 | Smith & Nephew plc | Wound dressing sealant and use thereof |
| US20160120706A1 (en) | 2013-03-15 | 2016-05-05 | Smith & Nephew Plc | Wound dressing sealant and use thereof |
| AU2014290513B2 (en) | 2013-07-18 | 2017-07-27 | The General Hospital Corporation | Vessel treatment systems, methods, and kits |
| CN105288720B (zh) * | 2015-10-19 | 2018-07-27 | 中国科学院苏州生物医学工程技术研究所 | 用于血管吻合的粘合型材 |
| CN108114314A (zh) * | 2017-05-03 | 2018-06-05 | 曲平波 | 一种可降解胸膜补片及其制备方法 |
| ES2947713T3 (es) | 2019-06-13 | 2023-08-17 | Hollister Inc | Productos de catéter urinario reutilizables |
| WO2020263859A1 (en) | 2019-06-25 | 2020-12-30 | Hollister Incorporated | Reusable urinary catheter products |
| CN112336910B (zh) * | 2019-08-08 | 2022-05-13 | 南京理工大学 | 一种含icg染料的激光生物组织焊接助焊剂 |
| US20220273365A1 (en) * | 2019-08-30 | 2022-09-01 | Arizona Board Of Regents On Behalf Of Arizona State University | Nerve Repair Using Laser Sealing |
| CN112294381A (zh) * | 2020-10-27 | 2021-02-02 | 中南大学湘雅医院 | 一种用于显微外科血管及淋巴管吻合的套管装置 |
| CN119867851A (zh) * | 2025-01-21 | 2025-04-25 | 徐州市彭康电子设备有限公司 | 一种神经内科用血管连接器 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996022054A1 (en) * | 1995-01-20 | 1996-07-25 | The Microsearch Foundation Of Australia | Method of tissue repair |
| WO1998016165A1 (en) * | 1996-10-16 | 1998-04-23 | Fusion Medical Technologies, Inc. | Films having improved characteristics and methods for their preparation and use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1205013A (en) * | 1984-03-19 | 1986-05-27 | Adolf Lindner | Method of producing a tissue adhesive |
| JPH05502386A (ja) * | 1989-09-12 | 1993-04-28 | ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニュー ヨーク | 色素で強化した接着剤をもつレーザーによる組織接合法 |
| US5156613A (en) * | 1991-02-13 | 1992-10-20 | Interface Biomedical Laboratories Corp. | Collagen welding rod material for use in tissue welding |
| US5749895A (en) * | 1991-02-13 | 1998-05-12 | Fusion Medical Technologies, Inc. | Method for bonding or fusion of biological tissue and material |
| CH681693A5 (https=) * | 1991-02-28 | 1993-05-14 | Pentapharm Ag | |
| US5713891A (en) * | 1995-06-02 | 1998-02-03 | Children's Medical Center Corporation | Modified solder for delivery of bioactive substances and methods of use thereof |
| WO1999051282A1 (en) * | 1998-04-06 | 1999-10-14 | Cornell Research Foundation, Inc. | Composition for tissue welding and method of use |
-
1998
- 1998-06-18 AU AUPP4214A patent/AUPP421498A0/en not_active Abandoned
-
1999
- 1999-06-18 CA CA002335323A patent/CA2335323A1/en not_active Abandoned
- 1999-06-18 NZ NZ50909999A patent/NZ509099A/xx unknown
- 1999-06-18 HK HK02101911.2A patent/HK1040939B/zh not_active IP Right Cessation
- 1999-06-18 US US09/719,889 patent/US7078378B1/en not_active Expired - Fee Related
- 1999-06-18 WO PCT/AU1999/000495 patent/WO1999065536A1/en not_active Ceased
- 1999-06-18 JP JP2000554413A patent/JP2002518102A/ja active Pending
- 1999-06-18 EP EP99927596A patent/EP1087795A4/en not_active Withdrawn
- 1999-06-18 IL IL14036899A patent/IL140368A0/xx not_active IP Right Cessation
- 1999-06-18 CN CNA2005100916076A patent/CN1935269A/zh active Pending
- 1999-06-18 MX MXPA00012716A patent/MXPA00012716A/es unknown
- 1999-06-18 CN CNB998097748A patent/CN1221291C/zh not_active Expired - Fee Related
-
2000
- 2000-12-18 IL IL140368A patent/IL140368A/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996022054A1 (en) * | 1995-01-20 | 1996-07-25 | The Microsearch Foundation Of Australia | Method of tissue repair |
| WO1998016165A1 (en) * | 1996-10-16 | 1998-04-23 | Fusion Medical Technologies, Inc. | Films having improved characteristics and methods for their preparation and use |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009099253A1 (ja) * | 2008-02-07 | 2009-08-13 | Riken | 可視光硬化型接着剤 |
| JP2015061604A (ja) * | 2009-03-10 | 2015-04-02 | ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ | 生物学的組織結合及び修復装置及びその使用方法 |
| JP2013510186A (ja) * | 2009-11-09 | 2013-03-21 | クルアスパンヌ | 金ナノ粒子と血清アルブミンおよび／またはコラーゲンとを含有するレーザー組織接合のための水性組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1087795A4 (en) | 2006-01-11 |
| HK1040939B (zh) | 2006-02-03 |
| NZ509099A (en) | 2004-12-24 |
| IL140368A (en) | 2006-10-31 |
| CN1221291C (zh) | 2005-10-05 |
| MXPA00012716A (es) | 2002-05-08 |
| CN1935269A (zh) | 2007-03-28 |
| CN1312727A (zh) | 2001-09-12 |
| HK1040939A1 (en) | 2002-06-28 |
| US7078378B1 (en) | 2006-07-18 |
| WO1999065536A1 (en) | 1999-12-23 |
| AUPP421498A0 (en) | 1998-07-09 |
| CA2335323A1 (en) | 1999-12-23 |
| IL140368A0 (en) | 2002-02-10 |
| EP1087795A1 (en) | 2001-04-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002518102A (ja) | 組織修復方法ｉｉ | |
| CA2340251C (en) | Insertable stent and methods of making and using same | |
| US6583117B2 (en) | Method of tissue repair | |
| CN1142749C (zh) | 弹性蛋白、基于弹性蛋白的生物材料及其制备方法 | |
| US20020052572A1 (en) | Resorbable anastomosis stents and plugs and their use in patients | |
| JP2003521326A (ja) | 外科手術に起因する穿刺を閉塞するための装置 | |
| Lauto et al. | Sutureless nerve repair with laser-activated chitosan adhesive: a pilot in vivo study | |
| AU768533B2 (en) | Method of tissue repair II | |
| WO2007030892A1 (en) | Method of tissue repair iii | |
| Wright et al. | Laser‐assisted end‐to‐end bioweld® anastomosis in an ovine model | |
| AU711199B2 (en) | Method of tissue repair | |
| Xie et al. | Sutureless end-to-end ureteral anastomosis using a new albumin stent and diode laser | |
| Werker | Alternative approaches to vascular anastomosis surgery | |
| HK1003613B (en) | Tissue repair solder |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050712 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060522 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100126 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20100622 |