JP2002515071A5 - - Google Patents

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Publication number
JP2002515071A5
JP2002515071A5 JP1999507430A JP50743099A JP2002515071A5 JP 2002515071 A5 JP2002515071 A5 JP 2002515071A5 JP 1999507430 A JP1999507430 A JP 1999507430A JP 50743099 A JP50743099 A JP 50743099A JP 2002515071 A5 JP2002515071 A5 JP 2002515071A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP1999507430A
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English (en)
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JP2002515071A (ja
JP4371179B2 (ja
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Priority claimed from US08/909,435 external-priority patent/US6734015B1/en
Application filed filed Critical
Priority claimed from PCT/US1998/013875 external-priority patent/WO1999001159A1/en
Publication of JP2002515071A publication Critical patent/JP2002515071A/ja
Publication of JP2002515071A5 publication Critical patent/JP2002515071A5/ja
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Publication of JP4371179B2 publication Critical patent/JP4371179B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Figure 2002515071
Figure 2002515071
Figure 2002515071
Figure 2002515071
JP50743099A 1997-07-04 1998-07-03 系列限定ニューロン前駆体 Expired - Fee Related JP4371179B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/909,435 US6734015B1 (en) 1997-07-04 1997-07-04 Isolation of lineage-restricted neuronal precursors
US08/909,435 1997-07-04
US09/109,858 1998-07-02
US09/109,858 US6787353B1 (en) 1997-07-04 1998-07-02 Lineage-restricted neuronal precursors and methods of isolation
PCT/US1998/013875 WO1999001159A1 (en) 1997-07-04 1998-07-03 Lineage-restricted neuronal precursors

Publications (3)

Publication Number Publication Date
JP2002515071A JP2002515071A (ja) 2002-05-21
JP2002515071A5 true JP2002515071A5 (ja) 2006-01-05
JP4371179B2 JP4371179B2 (ja) 2009-11-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP50743099A Expired - Fee Related JP4371179B2 (ja) 1997-07-04 1998-07-03 系列限定ニューロン前駆体

Country Status (8)

Country Link
US (1) US20050003531A1 (ja)
EP (1) EP1011732A4 (ja)
JP (1) JP4371179B2 (ja)
KR (1) KR20060002033A (ja)
AU (1) AU755657B2 (ja)
CA (1) CA2294737A1 (ja)
IL (1) IL133799A0 (ja)
WO (1) WO1999001159A1 (ja)

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US7544511B2 (en) 1996-09-25 2009-06-09 Neuralstem Biopharmaceuticals Ltd. Stable neural stem cell line methods
WO2000068359A1 (en) * 1999-05-07 2000-11-16 University Of Utah Research Foundation Lineage-restricted precursor cells isolated from mouse neural tube and mouse embryonic stem cells
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
EP1144671B1 (en) * 1999-02-12 2007-11-07 StemCells, Inc. Enriched central nervous system cell populations
DE19928210B4 (de) * 1999-06-19 2005-08-18 Neuroprogen Gmbh Leipzig Neuronales Zellmaterial und Verfahren zu dessen Herstellung
EP1762244A1 (en) * 1999-09-08 2007-03-14 Genetics Institute, LLC Bmp-9 compositions for inducing differentiation of cholinergic neurons
AU7355500A (en) * 1999-09-08 2001-04-10 Genetics Institute Inc. Bmp-9 compositions and methods for inducing differentiation of cholinergic neurons
US20050042749A1 (en) 2001-05-16 2005-02-24 Carpenter Melissa K. Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease
JP5943533B2 (ja) * 2000-05-17 2016-07-06 アステリアス バイオセラピューティクス インコーポレイテッド 神経前駆細胞の集団
US7250294B2 (en) * 2000-05-17 2007-07-31 Geron Corporation Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
US7211434B2 (en) 2000-09-29 2007-05-01 Van Der Kooy Derek Primitive neural stem cells and method for differentiation of stem cells to neural cells
CN101029302B (zh) * 2001-06-21 2011-03-30 杰龙公司 用于治疗帕金森病的多巴胺能神经元和具有增殖能力的前体细胞
US7285415B2 (en) 2002-07-11 2007-10-23 The Regents Of The University Of California Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US20050101014A1 (en) 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US20040185429A1 (en) 2002-12-09 2004-09-23 Judith Kelleher-Andersson Method for discovering neurogenic agents
US8293488B2 (en) 2002-12-09 2012-10-23 Neuralstem, Inc. Method for screening neurogenic agents
ES2537004T3 (es) 2004-11-17 2015-06-01 Neuralstem, Inc. Trasplante de células neurales humanas para el tratamiento de afecciones neurodegenerativas
JP2010500047A (ja) 2006-08-15 2010-01-07 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 間葉系幹細胞馴化培地
CN101679951B (zh) * 2007-04-17 2013-09-11 罗切斯特大学 端脑胶质限制性细胞群和相关组合物及方法
EP2014768A1 (en) * 2007-07-10 2009-01-14 Innovalor AG Neurons and methods for preparing them
EP2240536B1 (en) 2008-01-30 2019-09-04 Asterias Biotherapeutics, Inc. Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
US8716018B2 (en) 2008-03-17 2014-05-06 Agency For Science, Technology And Research Microcarriers for stem cell culture
WO2010008486A2 (en) 2008-06-24 2010-01-21 Parkinsons Institute Pluripotent cell lines and methods of use thereof
JP6243119B2 (ja) 2009-07-21 2017-12-06 エイビーティー ホールディング カンパニー 白血球溢出を低下させる幹細胞の使用
ES2690199T3 (es) 2009-07-21 2018-11-19 Abt Holding Company Uso de células madre para reducir la extravasación de leucocitos
EP2539436B1 (en) 2010-02-25 2021-09-22 ABT Holding Company Modulation of macrophage activation
CA2806904C (en) 2010-07-28 2018-11-27 Neuralstem, Inc. Methods for treating and/or reversing neurodegenerative diseases and/or disorders
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
KR102073530B1 (ko) 2011-06-06 2020-02-04 리제네시스 비브이비에이 중공 섬유 생물 반응기에서의 줄기 세포의 확장
EP2970877B1 (en) 2013-03-15 2018-07-25 Wake Forest University Health Sciences Neural progenitor cell differentiation
SG11201508403XA (en) 2013-04-12 2015-11-27 Saverio Lafrancesca Improving organs for transplantation
US20140322135A1 (en) 2013-04-30 2014-10-30 Katholieke Universiteit Leuven Cell therapy for myelodysplastic syndromes
CN105793411B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
CA2964927C (en) 2014-10-20 2019-07-30 Neuralstem, Inc. Stable neural stem cells comprising an exogenous polynucleotide coding for a growth factor and methods of use thereof
EP3266040A1 (en) * 2015-03-03 2018-01-10 Lutz Rebstock Inspection system

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US5087570A (en) * 1988-05-10 1992-02-11 Weissman Irving L Homogeneous mammalian hematopoietic stem cell composition
US5411883A (en) * 1989-12-26 1995-05-02 Somatix Therapy Corporation Proliferated neuron progenitor cell product and process
ATE240389T1 (de) * 1991-07-08 2003-05-15 Neurospheres Holdings Ltd Auf wachstumsfaktoren reagierende neurale vorläuferzellen, die in vitro vermehrt werden können.
US5175103A (en) * 1991-10-21 1992-12-29 Trustees Of University Of Pennsylvania Preparation of pure cultures of post-mitotic human neurons
US5589376A (en) * 1992-07-27 1996-12-31 California Institute Of Technology Mammalian neural crest stem cells
CA2148138C (en) * 1992-10-28 2002-01-08 Samuel Weiss Biological factors and neural stem cells
US5753505A (en) * 1995-07-06 1998-05-19 Emory University Neuronal progenitor cells and uses thereof

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