JP2002506970A - キャピラリー電気泳動装置 - Google Patents

キャピラリー電気泳動装置

Info

Publication number
JP2002506970A
JP2002506970A JP2000535921A JP2000535921A JP2002506970A JP 2002506970 A JP2002506970 A JP 2002506970A JP 2000535921 A JP2000535921 A JP 2000535921A JP 2000535921 A JP2000535921 A JP 2000535921A JP 2002506970 A JP2002506970 A JP 2002506970A
Authority
JP
Japan
Prior art keywords
channel
analyzer
substrate
radiation detector
array
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000535921A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002506970A5 (enExample
Inventor
ジョン ドクター ハサード,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial College of London
Original Assignee
Imperial College of London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial College of London filed Critical Imperial College of London
Publication of JP2002506970A publication Critical patent/JP2002506970A/ja
Publication of JP2002506970A5 publication Critical patent/JP2002506970A5/ja
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44791Microapparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44782Apparatus specially adapted therefor of a plurality of samples

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2000535921A 1998-03-12 1999-03-12 キャピラリー電気泳動装置 Pending JP2002506970A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9805301.0A GB9805301D0 (en) 1998-03-12 1998-03-12 Detector
GB9805301.0 1998-03-12
PCT/GB1999/000742 WO1999046590A1 (en) 1998-03-12 1999-03-12 Capillary electrophoresis device

Publications (2)

Publication Number Publication Date
JP2002506970A true JP2002506970A (ja) 2002-03-05
JP2002506970A5 JP2002506970A5 (enExample) 2006-04-20

Family

ID=10828454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000535921A Pending JP2002506970A (ja) 1998-03-12 1999-03-12 キャピラリー電気泳動装置

Country Status (7)

Country Link
US (1) US6752914B1 (enExample)
EP (1) EP1066512B1 (enExample)
JP (1) JP2002506970A (enExample)
AU (1) AU2740399A (enExample)
DE (1) DE69940425D1 (enExample)
GB (1) GB9805301D0 (enExample)
WO (1) WO1999046590A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005013905A (ja) * 2003-06-27 2005-01-20 Sumitomo Electric Ind Ltd 化学反応用マイクロチップおよびその製造方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2348864A1 (en) * 1998-11-12 2000-05-18 Mark A. Hayes Practical device for controlling ultrasmall volume flow
US7309409B2 (en) * 2001-01-26 2007-12-18 Biocal Technology, Inc. Multi-channel bio-separation cartridge
GB0125436D0 (en) 2001-10-23 2001-12-12 Deltadot Ltd Analysis of temperature-dependent molecular configurations
WO2003062815A1 (en) * 2002-01-18 2003-07-31 Biocal Technology, Inc. Multi-segment cartridge for bio-separation with multiplexed fluorescence detection
US20050238506A1 (en) * 2002-06-21 2005-10-27 The Charles Stark Draper Laboratory, Inc. Electromagnetically-actuated microfluidic flow regulators and related applications
US7867194B2 (en) 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
WO2005072793A1 (en) * 2004-01-29 2005-08-11 The Charles Stark Draper Laboratory, Inc. Implantable drug delivery apparatus
US9046192B2 (en) 2007-01-31 2015-06-02 The Charles Stark Draper Laboratory, Inc. Membrane-based fluid control in microfluidic devices
WO2009020682A2 (en) 2007-05-08 2009-02-12 The Trustees Of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
CA2808576A1 (en) 2009-09-30 2011-04-07 Quantapore, Inc. Ultrafast sequencing of biological polymers using a labeled nanopore
JP6162047B2 (ja) 2011-02-02 2017-07-12 ザ チャールズ スターク ドレイパー ラボラトリー インク 薬物送達装置
US9651539B2 (en) 2012-10-28 2017-05-16 Quantapore, Inc. Reducing background fluorescence in MEMS materials by low energy ion beam treatment
AU2014268322B2 (en) 2013-05-24 2019-01-24 Quantapore, Inc. Nanopore-based nucleic acid analysis with mixed FRET detection
WO2016057829A1 (en) 2014-10-10 2016-04-14 Quantapore, Inc. Nanopore-based polymer analysis with mutually-quenching fluorescent labels
WO2016065339A1 (en) 2014-10-24 2016-04-28 Quantapore, Inc. Efficient optical analysis of polymers using arrays of nanostructures
US10823721B2 (en) 2016-07-05 2020-11-03 Quantapore, Inc. Optically based nanopore sequencing

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571410A (en) * 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
US5757482A (en) * 1995-04-20 1998-05-26 Perseptive Biosystems, Inc. Module for optical detection in microscale fluidic analyses
GB9509410D0 (en) * 1995-05-10 1995-07-05 Imperial College Molecular imaging
GB9517930D0 (en) * 1995-09-01 1995-11-01 Imperial College Electronically gated microstructure
GB9517927D0 (en) * 1995-09-01 1995-11-01 Imperial College Optoelectrically gated microstructure
US5867266A (en) * 1996-04-17 1999-02-02 Cornell Research Foundation, Inc. Multiple optical channels for chemical analysis
WO1998010122A1 (en) * 1996-09-03 1998-03-12 Northeastern University Microfabricated hybrid capillary array and multichannel detection assembly

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005013905A (ja) * 2003-06-27 2005-01-20 Sumitomo Electric Ind Ltd 化学反応用マイクロチップおよびその製造方法

Also Published As

Publication number Publication date
EP1066512B1 (en) 2009-02-18
EP1066512A1 (en) 2001-01-10
WO1999046590A1 (en) 1999-09-16
US6752914B1 (en) 2004-06-22
AU2740399A (en) 1999-09-27
DE69940425D1 (de) 2009-04-02
GB9805301D0 (en) 1998-05-06

Similar Documents

Publication Publication Date Title
JP2002506970A (ja) キャピラリー電気泳動装置
US6613210B1 (en) Molecular imaging
JP3626956B2 (ja) 多毛管蛍光検出システム
US6344325B1 (en) Methods for analysis and sorting of polynucleotides
JP4034351B2 (ja) 粒子近接表面の光制御した動電学的アッセンブリ
US20020126276A1 (en) Method, apparatus and flow cell for high sensitivity detection of fluorescent molecules
JP3613032B2 (ja) キャピラリーアレイ電気泳動装置
JPH07209251A (ja) 電気泳動装置
JPH07503322A (ja) 細管列共焦蛍光スキャナー及び方法
DE102006058575B4 (de) Multiplex-CE-Fluoreszenzsystem
JP5342031B2 (ja) 微細加工チャネルデバイス上の試料成分の高分解能分離装置および方法
CN1119275A (zh) 电泳多试样组分采集器
US6942773B1 (en) Particle sizer and DNA sequencer
WO2001068225A1 (en) Micropreparative isoelectric focussing
US6800438B2 (en) Imager for DNA sequencer
KR20030079577A (ko) 레이저 유발 표면형광 검출 장치
EP0616212B1 (en) Apparatus and method for reading a gel electrophoresis pattern
JP2000019114A (ja) 微弱蛍光検出方法および微弱蛍光検出装置
JP2003526096A (ja) 核酸、dna、rna、pna及び蛋白質などの分子化合物のハイブリダイゼーションを同時かつ多角的に検出し定量化するための方法及びシステム
JPH0552810A (ja) 電気泳動装置
JP2004144532A (ja) キャピラリー泳動分取システム及び分取方法
JP3570425B2 (ja) キャピラリー電気泳動装置
Kamahori et al. Capillary array electrophoresis analyzer
Sauer et al. Single-Molecule Detection in Biology with Multiplex Dyes and Pulsed Semiconductor Lasers
Castro et al. Single-molecule electrophoresis: applications to biomolecular detection

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20040423

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20040423

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060227

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060227

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20081031

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090127

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090203

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20090625