JP2002502611A - ヒトヘパラナーゼポリペプチドおよびｃＤＮＡ - Google Patents
ヒトヘパラナーゼポリペプチドおよびｃＤＮＡInfo
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- JP2002502611A JP2002502611A JP2000530619A JP2000530619A JP2002502611A JP 2002502611 A JP2002502611 A JP 2002502611A JP 2000530619 A JP2000530619 A JP 2000530619A JP 2000530619 A JP2000530619 A JP 2000530619A JP 2002502611 A JP2002502611 A JP 2002502611A
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- C12Y—ENZYMES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9802725.3A GB9802725D0 (en) | 1998-02-09 | 1998-02-09 | Organic compounds |
| GB9802725.3 | 1998-02-09 | ||
| PCT/EP1999/000777 WO1999040207A1 (en) | 1998-02-09 | 1999-02-05 | HUMAN HEPARANASE POLYPEPTIDE AND cDNA |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002502611A true JP2002502611A (ja) | 2002-01-29 |
| JP2002502611A5 JP2002502611A5 (https=) | 2006-03-30 |
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Family Applications (1)
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| JP2000530619A Pending JP2002502611A (ja) | 1998-02-09 | 1999-02-05 | ヒトヘパラナーゼポリペプチドおよびｃＤＮＡ |
Country Status (6)
| Country | Link |
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| US (2) | US6461848B1 (https=) |
| EP (1) | EP1054980A1 (https=) |
| JP (1) | JP2002502611A (https=) |
| AU (1) | AU2831999A (https=) |
| GB (1) | GB9802725D0 (https=) |
| WO (1) | WO1999040207A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6348344B1 (en) * | 1997-09-02 | 2002-02-19 | Insight Strategy & Marketing Ltd. | Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same |
| US5968822A (en) | 1997-09-02 | 1999-10-19 | Pecker; Iris | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells |
| US6562950B2 (en) * | 1997-09-02 | 2003-05-13 | Insight Strategy & Marketing Ltd. | Heparanase activity neutralizing anti-heparanase monoclonal antibody |
| AU2759199A (en) * | 1998-02-24 | 1999-09-15 | Pharmacia & Upjohn Company | Human platelet heparanase polypeptides, polynucleotide molecules that encode them, and methods for the identification of compounds that alter heparanase activity |
| US20020068054A1 (en) * | 2000-09-11 | 2002-06-06 | Insight Strategy & Marketing Ltd. And Hadasit Medical Research Services And Development Ltd. | Therapeutic and cosmetic uses of heparanases |
| JP2003510053A (ja) * | 1999-09-23 | 2003-03-18 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | ヘパラナーゼ蛋白質ファミリーの１種、ヘパラナーゼ−２ |
| WO2001046392A2 (en) | 1999-12-22 | 2001-06-28 | Oxford Glycosciences (Uk) Ltd. | Homologues of human heparanase and splice variants thereof |
| EP1356083A2 (en) | 2000-09-15 | 2003-10-29 | Reddy US Therapeutics, Inc. | Methods and compositions for glycosidase assays |
| FR2818131B1 (fr) * | 2000-12-14 | 2005-02-11 | Oreal | Composition cosmetique comprenant de l'heparanase |
| CH696701A5 (de) | 2001-12-18 | 2007-10-15 | Hoffmann La Roche | Verfahren zum Testen eines Mittels auf dessen Fähigkeit, die Heparanaseaktivität zu hemmen. |
| EP1479764A1 (en) | 2003-05-19 | 2004-11-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Heparanase-derived peptides for vaccination of tumor patients |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362641A (en) * | 1989-08-23 | 1994-11-08 | Hadassah Medical Organization Kiryat Hadassah | Heparanase derived from human Sk-Hep-1 cell line |
| WO1995004158A1 (en) * | 1993-07-29 | 1995-02-09 | The Upjohn Company | Use of heparanase to identify and isolate anti-heparanase compound |
| AUPN261895A0 (en) | 1995-04-28 | 1995-05-18 | Australian National University, The | Preparation and use of sulfated oligosaccharides |
| US5968822A (en) * | 1997-09-02 | 1999-10-19 | Pecker; Iris | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells |
| US20040213789A1 (en) * | 1997-09-02 | 2004-10-28 | Oron Yacoby-Zeevi | Heparanase activity neutralizing anti-heparanase monoclonal antibody and other anti-heparanase antibodies |
| JP2002510462A (ja) * | 1997-10-28 | 2002-04-09 | ジ・オーストラリアン・ナショナル・ユニバーシティー | 哺乳類のエンドグルクロニダーゼをコードする単離された核酸分子およびその使用 |
-
1998
- 1998-02-09 GB GBGB9802725.3A patent/GB9802725D0/en not_active Ceased
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1999
- 1999-02-05 EP EP99908854A patent/EP1054980A1/en not_active Withdrawn
- 1999-02-05 WO PCT/EP1999/000777 patent/WO1999040207A1/en not_active Ceased
- 1999-02-05 US US09/601,777 patent/US6461848B1/en not_active Expired - Fee Related
- 1999-02-05 AU AU28319/99A patent/AU2831999A/en not_active Abandoned
- 1999-02-05 JP JP2000530619A patent/JP2002502611A/ja active Pending
-
2002
- 2002-03-27 US US10/107,859 patent/US20020115183A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6461848B1 (en) | 2002-10-08 |
| WO1999040207A1 (en) | 1999-08-12 |
| GB9802725D0 (en) | 1998-04-08 |
| AU2831999A (en) | 1999-08-23 |
| EP1054980A1 (en) | 2000-11-29 |
| US20020115183A1 (en) | 2002-08-22 |
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